Guest guest Posted July 10, 2006 Report Share Posted July 10, 2006 my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 10, 2006 Report Share Posted July 10, 2006 my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 12, 2006 Report Share Posted July 12, 2006 My son just started transdermal Actos this week. It was also prescribed for brain inflammation. We also tried LDN with bad results. So far, so good on the Actos. We are starting out at a low dose and working our way up. Trudy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of vickila1@...Sent: Monday, July 10, 2006 11:47 PMmb12 valtrex Subject: Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 12, 2006 Report Share Posted July 12, 2006 My son just started transdermal Actos this week. It was also prescribed for brain inflammation. We also tried LDN with bad results. So far, so good on the Actos. We are starting out at a low dose and working our way up. Trudy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of vickila1@...Sent: Monday, July 10, 2006 11:47 PMmb12 valtrex Subject: Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 In a message dated 7/13/2006 7:11:04 AM Pacific Daylight Time, elfischer@... writes: Vicki: Is the risperdal working and if so, what symptoms is it helping, or is it just a global improvement? Curious… laura, tx for asking. the risperdal is okay. just okay at this time. my son has only been on the med for 3 wks. doc says it takes at least 4-6 wks to tell. we had a bump in the beginning of this road as the pharmacy put the incorrect dosage on the bottle and so my son was getting twice the dose he should of. when i caught the error, a wk already passed. so, that had to be corrected. now, my son is on 1 tab in am and 1 at night. ideally, the doc wants one tab 3x day. we are building up. as for improvements, the main reason he is on risperdal is because after 6 yrs of bio medical treatments, many improvements have been seen which im blessed. however, the hyperness, impulsivity and pica have NEVER gotten better. my son is 9 now. well, he is still hyper but not as much. meaning, instead of bouncing off the walls like a ball in a pin ball machine, he just walks around the house a lot. he's a busy body. he used to run thru the house constantly. now, it's walking around. room to room to room... at school they report he is more focused and is able to complete his work more than before. he is a little more cooperative. so, it appears the improvements are seen more at school than home cause school is more structured. what i have noticed which is interesting is that my son, who is apraxic (babbles constantly and some word approximations and only about 5 intelligible words) is using "speech" more appropriately. i have also noticed an increase in a few words to. for instance, he wanted to go outside. so, he grabbed me by the hand and said "go". when he wants go to the back yard, he will say "back" for back yard. before, he would just babble and grab my hand and lead me to the location desired. i dont think risperdal is known for increasing language, but, it is certainly doing something along those lines in my tough nut. vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 In a message dated 7/13/2006 7:11:04 AM Pacific Daylight Time, elfischer@... writes: Vicki: Is the risperdal working and if so, what symptoms is it helping, or is it just a global improvement? Curious… laura, tx for asking. the risperdal is okay. just okay at this time. my son has only been on the med for 3 wks. doc says it takes at least 4-6 wks to tell. we had a bump in the beginning of this road as the pharmacy put the incorrect dosage on the bottle and so my son was getting twice the dose he should of. when i caught the error, a wk already passed. so, that had to be corrected. now, my son is on 1 tab in am and 1 at night. ideally, the doc wants one tab 3x day. we are building up. as for improvements, the main reason he is on risperdal is because after 6 yrs of bio medical treatments, many improvements have been seen which im blessed. however, the hyperness, impulsivity and pica have NEVER gotten better. my son is 9 now. well, he is still hyper but not as much. meaning, instead of bouncing off the walls like a ball in a pin ball machine, he just walks around the house a lot. he's a busy body. he used to run thru the house constantly. now, it's walking around. room to room to room... at school they report he is more focused and is able to complete his work more than before. he is a little more cooperative. so, it appears the improvements are seen more at school than home cause school is more structured. what i have noticed which is interesting is that my son, who is apraxic (babbles constantly and some word approximations and only about 5 intelligible words) is using "speech" more appropriately. i have also noticed an increase in a few words to. for instance, he wanted to go outside. so, he grabbed me by the hand and said "go". when he wants go to the back yard, he will say "back" for back yard. before, he would just babble and grab my hand and lead me to the location desired. i dont think risperdal is known for increasing language, but, it is certainly doing something along those lines in my tough nut. vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 Vicki: Is the risperdal working and if so, what symptoms is it helping, or is it just a global improvement? Curious… Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 Vicki: Is the risperdal working and if so, what symptoms is it helping, or is it just a global improvement? Curious… Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 OK, just my philosophy here... I think it's OK to use meds for brian inflamation, but I like to say, " Why is the child's brain inflamed? " I can tell you one reason. Viruses. Herpes virus can cause inflamation on the brain and can cause autism all by itself. So trying Actos or even steroids to calm the inflamation for a period of time is fine, IMO, but I would strongly consider a trial of Valtrex with an antifungal and see if that works on the cause of the inflamation. Here are a few journal articles to support the discussion. ----- Pubmed peer reviewed articles that support herpes virus and/or viral encephalitis in autism. #1. Eur Child Adolesc Psychiatry. 2002 Jun;11(3):142-6. Related Articles, Links Autistic symptoms following herpes encephalitis. Ghaziuddin M, Al-Khouri I, Ghaziuddin N. Division of Child and Adolescent Psychiatry, University of Michigan Medical Center, Ann Arbor 48109-0390, USA. mghaziud@... Autism is a childhood onset neurodevelopmental disorder characterized by reciprocal social deficits, communication impairment, and rigid ritualistic interests, with the onset almost always before three years of age. Although the etiology of the disorder is strongly influenced by genes, environmental factors are also important. In this context, several reports have described its association with known medical conditions, including infections affecting the central nervous system. In this report, we describe an 11-year-old Asian youngster who developed the symptoms of autism following an episode of herpes encephalitis. In contrast to previous similar reports, imaging studies suggested a predominant involvement of the frontal lobes. At follow-up after three years, he continued to show the core deficits of autism. This case further supports the role of environmental factors, such as infections, in the etiology of autism, and suggests that in a minority of cases, autistic symptoms can develop in later childhood. PMID: 12369775 [PubMed - indexed for MEDLINE] ------ #2 J Neurovirol. 2005 Feb;11(1):1-10. Autistic disorder and viral infections. Libbey JE, Sweeten TL, McMahon WM, Fujinami RS. Department of Neurology, University of Utah, Salt Lake City, Utah 84132-2305, USA. Autistic disorder (autism) is a behaviorally defined developmental disorder with a wide range of behaviors. Although the etiology of autism is unknown, data suggest that autism results from multiple etiologies with both genetic and environmental contributions, which may explain the spectrum of behaviors seen in this disorder. One proposed etiology for autism is viral infection very early in development. The mechanism, by which viral infection may lead to autism, be it through direct infection of the central nervous system (CNS), through infection elsewhere in the body acting as a trigger for disease in the CNS, through alteration of the immune response of the mother or offspring, or through a combination of these, is not yet known. Animal models in which early viral infection results in behavioral changes later in life include the influenza virus model in pregnant mice and the Borna disease virus model in newborn rats. Many studies over the years have presented evidence both for and against the association of autism with various viral infections. The best association to date has been made between congenital rubella and autism; however, members of the herpes virus family may also have a role in autism. Recently, controversy has arisen as to the involvement of measles virus and/or the measles, mumps, rubella (MMR) vaccine in the development of autism. Biological assays lend support to the association between measles virus or MMR and autism whereas epidemiologic studies show no association between MMR and autism. Further research is needed to clarify both the mechanisms whereby viral infection early in development may lead to autism and the possible involvement of the MMR vaccine in the development of autism. PMID: 15804954 [PubMed - indexed for MEDLINE] ----- #3 Med Hypotheses. 2001 Dec;57(6):714-7. Related Articles, Links Anterior insular cortex: linking intestinal pathology and brain function in autism-spectrum subgroups. Binstock T. Institute for Molecular Introspections, Estes Park, Colorado 80517, USA. aspergerian@... Autism includes deficits in communications skills and is associated with intestinal pathology. Numerous parents and some physicians report that an autistic child's attention and language improve in response to treatments which eliminate certain dietary antigens and/or which improve intestinal health. For at least some autism-spectrum children, the link between intestinal pathology, attention, and language may derive from shared neuroanatomic pathways within the anterior insular cortex (aIC); from a neurotrophic virus such as herpes simplex (HSV) migrating within afferents to the insular cortex; and/or from synaptic exhaustion in the aIC as induced by chronically inappropriate neuronal activity in the enteric nervous system and/or its vagal efferents. PMID: 11918432 [PubMed - indexed for MEDLINE] ------------ #4 J Autism Dev Disord. 1992 Mar;22(1):107-13. Related Articles, Links Brief report: autism and herpes simplex encephalitis. Ghaziuddin M, Tsai LY, Eilers L, Ghaziuddin N. Department of Child and Adolescent Psychiatry, University of Michigan Hospital, Ann Arbor 48109-0390. Publication Types: Case Reports PMID: 1592760 [PubMed - indexed for MEDLINE] ---------------- #5 Can J Psychiatry. 1991 Nov;36(9):686-92. Related Articles, Links Autism: its primary psychological and neurological deficit. Fotheringham JB. Department of Psychiatry, Queen's University, Kingston, Ontario. Autism is a perplexing condition because of its unique presenting signs and high degree of variability. Evidence is presented that the basic underlying information processing disorder is a dysfunction of the appreciation of the emotional significance of incoming stimuli and attaching motivational value to the stimuli. It is proposed that this dysfunction occurs when the amygdaloid nucleus and/or its connections are disrupted, resulting in the variability of the presentation of this syndrome among individuals. Herpes simplex encephalitis sometimes results in signs of autism. The virus has a predilection to attack specific areas of the brain, which provides information on the probable underlying neurological dysfunction in autism. Publication Types: Review Review, Tutorial ---------------- #6 Dev Med Child Neurol. 1991 Oct;33(10):920-4 Autistic syndrome with onset at age 31 years: herpes encephalitis as a possible model for childhood autism. Gillberg IC. Department of Pediatrics and Child Psychiatry, University of Goteborg, Sweden. The author describes a previously healthy man who contracted herpes encephalitis at the age of 31 years, and over the following months developed all the symptoms considered diagnostic of autism. This case report casts doubt on the notion of autism as an exclusively developmental disorder. It is suggested that temporal lobe damage may cause autism in some cases. PMID: 1743418 [PubMed - indexed for MEDLINE] ------------------ #7 J Autism Dev Disord. 1986 Sep;16(3):369-75. Onset at age 14 of a typical autistic syndrome. A case report of a girl with herpes simplex encephalitis. Gillberg C. Publication Types: Case Reports PMID: 3558293 [PubMed - indexed for MEDLINE] ------------------- #8 Acta Psychiatr Scand. 1982 Jul;66(1):42-9. Herpes simplex virus (HSV) antibodies in child psychiatric patients and normal children. Sylvester nsen O, Vejlsgaard Goldschmidt V, Faber Vestergaard B. The prevalence of herpes simplex virus (HSV) antibodies has been investigated in 123 child psychiatric patients and 86 normal children. HSV antibodies were measured by ELISA technique. The prevalence of HSV antibodies in different diagnostic groups (conduct disorder, emotional disorder, hyperkinetic syndrome, anorexia nervosa, infantile autism and borderline schizophrenia in childhood) was compared with age-matched normal children, but no significant differences were found. PMID: 6289609 [PubMed - indexed for MEDLINE] -------------------- #9 Arch Neurol. 1981 Mar;38(3):191-4. Related Articles, Links Acquired reversible autistic syndrome in acute encephalopathic illness in children. DeLong GR, Bean SC, Brown FR 3rd. In seeking the neurologic substrate of the autistic syndrome of childhood, previous studies have implicated the medial temporal lobe or the ring of mesolimbic cortex located in the mesial frontal and temporal lobes. During an acute encephalopathic illness, a clinical picture developed in three children that was consistent with infantile autism. This development was reversible. It was differentiated from acquired epileptic aphasia, and the language disorder was differentiated aphasia. One child has rises in serum herpes simplex titers, and a computerized tomographic (CT) scan revealed an extensive lesion of the temporal lobes, predominantly on the left. The other two, with similar clinical syndromes, had normal CT scans, and no etiologic agent was defined. These cases are examples of an acquired and reversible autistic syndrome in childhood, emphasizing the clinical similarities to bilateral medial temporal lobe disease as described in man, including the Kluver-Bucy syndrome seen in postencephalitic as well as postsurgical states. Publication Types: Case Reports PMID: 6162440 [PubMed - indexed for MEDLINE] -------------------------- > > my son's doc wanted him to try actos to help bring down brain inflammation, > not to treat viruses. my son's brain is way off balance and is high in > excitotoxins. i also tried LDN two separate times with horrible results (i tell > you, i have a tough nut!). from what i have read about ldn, i just KNEW this > would be a good match for him. oh well... > > my son has the actos but was only on it for a few days very low dose. i > stopped cause we started the risperdal and my son cannot tolerate many rx meds > at the same time. i needed my son to be on as less stuff as possible to see > if this risperdal thing would work. > > i believe i read on another list that some parents are using tumeric to work > on the inflammation... > > vicki > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 OK, just my philosophy here... I think it's OK to use meds for brian inflamation, but I like to say, " Why is the child's brain inflamed? " I can tell you one reason. Viruses. Herpes virus can cause inflamation on the brain and can cause autism all by itself. So trying Actos or even steroids to calm the inflamation for a period of time is fine, IMO, but I would strongly consider a trial of Valtrex with an antifungal and see if that works on the cause of the inflamation. Here are a few journal articles to support the discussion. ----- Pubmed peer reviewed articles that support herpes virus and/or viral encephalitis in autism. #1. Eur Child Adolesc Psychiatry. 2002 Jun;11(3):142-6. Related Articles, Links Autistic symptoms following herpes encephalitis. Ghaziuddin M, Al-Khouri I, Ghaziuddin N. Division of Child and Adolescent Psychiatry, University of Michigan Medical Center, Ann Arbor 48109-0390, USA. mghaziud@... Autism is a childhood onset neurodevelopmental disorder characterized by reciprocal social deficits, communication impairment, and rigid ritualistic interests, with the onset almost always before three years of age. Although the etiology of the disorder is strongly influenced by genes, environmental factors are also important. In this context, several reports have described its association with known medical conditions, including infections affecting the central nervous system. In this report, we describe an 11-year-old Asian youngster who developed the symptoms of autism following an episode of herpes encephalitis. In contrast to previous similar reports, imaging studies suggested a predominant involvement of the frontal lobes. At follow-up after three years, he continued to show the core deficits of autism. This case further supports the role of environmental factors, such as infections, in the etiology of autism, and suggests that in a minority of cases, autistic symptoms can develop in later childhood. PMID: 12369775 [PubMed - indexed for MEDLINE] ------ #2 J Neurovirol. 2005 Feb;11(1):1-10. Autistic disorder and viral infections. Libbey JE, Sweeten TL, McMahon WM, Fujinami RS. Department of Neurology, University of Utah, Salt Lake City, Utah 84132-2305, USA. Autistic disorder (autism) is a behaviorally defined developmental disorder with a wide range of behaviors. Although the etiology of autism is unknown, data suggest that autism results from multiple etiologies with both genetic and environmental contributions, which may explain the spectrum of behaviors seen in this disorder. One proposed etiology for autism is viral infection very early in development. The mechanism, by which viral infection may lead to autism, be it through direct infection of the central nervous system (CNS), through infection elsewhere in the body acting as a trigger for disease in the CNS, through alteration of the immune response of the mother or offspring, or through a combination of these, is not yet known. Animal models in which early viral infection results in behavioral changes later in life include the influenza virus model in pregnant mice and the Borna disease virus model in newborn rats. Many studies over the years have presented evidence both for and against the association of autism with various viral infections. The best association to date has been made between congenital rubella and autism; however, members of the herpes virus family may also have a role in autism. Recently, controversy has arisen as to the involvement of measles virus and/or the measles, mumps, rubella (MMR) vaccine in the development of autism. Biological assays lend support to the association between measles virus or MMR and autism whereas epidemiologic studies show no association between MMR and autism. Further research is needed to clarify both the mechanisms whereby viral infection early in development may lead to autism and the possible involvement of the MMR vaccine in the development of autism. PMID: 15804954 [PubMed - indexed for MEDLINE] ----- #3 Med Hypotheses. 2001 Dec;57(6):714-7. Related Articles, Links Anterior insular cortex: linking intestinal pathology and brain function in autism-spectrum subgroups. Binstock T. Institute for Molecular Introspections, Estes Park, Colorado 80517, USA. aspergerian@... Autism includes deficits in communications skills and is associated with intestinal pathology. Numerous parents and some physicians report that an autistic child's attention and language improve in response to treatments which eliminate certain dietary antigens and/or which improve intestinal health. For at least some autism-spectrum children, the link between intestinal pathology, attention, and language may derive from shared neuroanatomic pathways within the anterior insular cortex (aIC); from a neurotrophic virus such as herpes simplex (HSV) migrating within afferents to the insular cortex; and/or from synaptic exhaustion in the aIC as induced by chronically inappropriate neuronal activity in the enteric nervous system and/or its vagal efferents. PMID: 11918432 [PubMed - indexed for MEDLINE] ------------ #4 J Autism Dev Disord. 1992 Mar;22(1):107-13. Related Articles, Links Brief report: autism and herpes simplex encephalitis. Ghaziuddin M, Tsai LY, Eilers L, Ghaziuddin N. Department of Child and Adolescent Psychiatry, University of Michigan Hospital, Ann Arbor 48109-0390. Publication Types: Case Reports PMID: 1592760 [PubMed - indexed for MEDLINE] ---------------- #5 Can J Psychiatry. 1991 Nov;36(9):686-92. Related Articles, Links Autism: its primary psychological and neurological deficit. Fotheringham JB. Department of Psychiatry, Queen's University, Kingston, Ontario. Autism is a perplexing condition because of its unique presenting signs and high degree of variability. Evidence is presented that the basic underlying information processing disorder is a dysfunction of the appreciation of the emotional significance of incoming stimuli and attaching motivational value to the stimuli. It is proposed that this dysfunction occurs when the amygdaloid nucleus and/or its connections are disrupted, resulting in the variability of the presentation of this syndrome among individuals. Herpes simplex encephalitis sometimes results in signs of autism. The virus has a predilection to attack specific areas of the brain, which provides information on the probable underlying neurological dysfunction in autism. Publication Types: Review Review, Tutorial ---------------- #6 Dev Med Child Neurol. 1991 Oct;33(10):920-4 Autistic syndrome with onset at age 31 years: herpes encephalitis as a possible model for childhood autism. Gillberg IC. Department of Pediatrics and Child Psychiatry, University of Goteborg, Sweden. The author describes a previously healthy man who contracted herpes encephalitis at the age of 31 years, and over the following months developed all the symptoms considered diagnostic of autism. This case report casts doubt on the notion of autism as an exclusively developmental disorder. It is suggested that temporal lobe damage may cause autism in some cases. PMID: 1743418 [PubMed - indexed for MEDLINE] ------------------ #7 J Autism Dev Disord. 1986 Sep;16(3):369-75. Onset at age 14 of a typical autistic syndrome. A case report of a girl with herpes simplex encephalitis. Gillberg C. Publication Types: Case Reports PMID: 3558293 [PubMed - indexed for MEDLINE] ------------------- #8 Acta Psychiatr Scand. 1982 Jul;66(1):42-9. Herpes simplex virus (HSV) antibodies in child psychiatric patients and normal children. Sylvester nsen O, Vejlsgaard Goldschmidt V, Faber Vestergaard B. The prevalence of herpes simplex virus (HSV) antibodies has been investigated in 123 child psychiatric patients and 86 normal children. HSV antibodies were measured by ELISA technique. The prevalence of HSV antibodies in different diagnostic groups (conduct disorder, emotional disorder, hyperkinetic syndrome, anorexia nervosa, infantile autism and borderline schizophrenia in childhood) was compared with age-matched normal children, but no significant differences were found. PMID: 6289609 [PubMed - indexed for MEDLINE] -------------------- #9 Arch Neurol. 1981 Mar;38(3):191-4. Related Articles, Links Acquired reversible autistic syndrome in acute encephalopathic illness in children. DeLong GR, Bean SC, Brown FR 3rd. In seeking the neurologic substrate of the autistic syndrome of childhood, previous studies have implicated the medial temporal lobe or the ring of mesolimbic cortex located in the mesial frontal and temporal lobes. During an acute encephalopathic illness, a clinical picture developed in three children that was consistent with infantile autism. This development was reversible. It was differentiated from acquired epileptic aphasia, and the language disorder was differentiated aphasia. One child has rises in serum herpes simplex titers, and a computerized tomographic (CT) scan revealed an extensive lesion of the temporal lobes, predominantly on the left. The other two, with similar clinical syndromes, had normal CT scans, and no etiologic agent was defined. These cases are examples of an acquired and reversible autistic syndrome in childhood, emphasizing the clinical similarities to bilateral medial temporal lobe disease as described in man, including the Kluver-Bucy syndrome seen in postencephalitic as well as postsurgical states. Publication Types: Case Reports PMID: 6162440 [PubMed - indexed for MEDLINE] -------------------------- > > my son's doc wanted him to try actos to help bring down brain inflammation, > not to treat viruses. my son's brain is way off balance and is high in > excitotoxins. i also tried LDN two separate times with horrible results (i tell > you, i have a tough nut!). from what i have read about ldn, i just KNEW this > would be a good match for him. oh well... > > my son has the actos but was only on it for a few days very low dose. i > stopped cause we started the risperdal and my son cannot tolerate many rx meds > at the same time. i needed my son to be on as less stuff as possible to see > if this risperdal thing would work. > > i believe i read on another list that some parents are using tumeric to work > on the inflammation... > > vicki > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 where did you purchase your transdermal actos? thanks, RE: Actose - carole My son just started transdermal Actos this week. It was also prescribed for brain inflammation. We also tried LDN with bad results. So far, so good on the Actos. We are starting out at a low dose and working our way up. Trudy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of vickila1@...Sent: Monday, July 10, 2006 11:47 PMmb12 valtrex Subject: Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2006 Report Share Posted July 13, 2006 where did you purchase your transdermal actos? thanks, RE: Actose - carole My son just started transdermal Actos this week. It was also prescribed for brain inflammation. We also tried LDN with bad results. So far, so good on the Actos. We are starting out at a low dose and working our way up. Trudy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of vickila1@...Sent: Monday, July 10, 2006 11:47 PMmb12 valtrex Subject: Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 14, 2006 Report Share Posted July 14, 2006 Silsby Pharmacy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of Dr. Graham-GarzaSent: Friday, July 14, 2006 1:03 AMmb12 valtrex Subject: Re: Actose - carole where did you purchase your transdermal actos? thanks, RE: Actose - carole My son just started transdermal Actos this week. It was also prescribed for brain inflammation. We also tried LDN with bad results. So far, so good on the Actos. We are starting out at a low dose and working our way up. Trudy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of vickila1@...Sent: Monday, July 10, 2006 11:47 PMmb12 valtrex Subject: Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 14, 2006 Report Share Posted July 14, 2006 Silsby Pharmacy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of Dr. Graham-GarzaSent: Friday, July 14, 2006 1:03 AMmb12 valtrex Subject: Re: Actose - carole where did you purchase your transdermal actos? thanks, RE: Actose - carole My son just started transdermal Actos this week. It was also prescribed for brain inflammation. We also tried LDN with bad results. So far, so good on the Actos. We are starting out at a low dose and working our way up. Trudy -----Original Message-----From: mb12 valtrex [mailto:mb12 valtrex ]On Behalf Of vickila1@...Sent: Monday, July 10, 2006 11:47 PMmb12 valtrex Subject: Re: Actose - carole my son's doc wanted him to try actos to help bring down brain inflammation, not to treat viruses. my son's brain is way off balance and is high in excitotoxins. i also tried LDN two separate times with horrible results (i tell you, i have a tough nut!). from what i have read about ldn, i just KNEW this would be a good match for him. oh well... my son has the actos but was only on it for a few days very low dose. i stopped cause we started the risperdal and my son cannot tolerate many rx meds at the same time. i needed my son to be on as less stuff as possible to see if this risperdal thing would work. i believe i read on another list that some parents are using tumeric to work on the inflammation... vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2006 Report Share Posted July 19, 2006 > > > > my son's doc wanted him to try actos to help bring down brain inflammation, > > not to treat viruses. my son's brain is way off balance and is high in > > excitotoxins. i also tried LDN two separate times with horrible results (i tell > > you, i have a tough nut!). from what i have read about ldn, i just KNEW this > > would be a good match for him. oh well... > > > > my son has the actos but was only on it for a few days very low dose. i > > stopped cause we started the risperdal and my son cannot tolerate many rx meds > > at the same time. i needed my son to be on as less stuff as possible to see > > if this risperdal thing would work. > > > > i believe i read on another list that some parents are using tumeric to work > > on the inflammation... > > > > vicki > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2006 Report Share Posted July 19, 2006 > > > > my son's doc wanted him to try actos to help bring down brain inflammation, > > not to treat viruses. my son's brain is way off balance and is high in > > excitotoxins. i also tried LDN two separate times with horrible results (i tell > > you, i have a tough nut!). from what i have read about ldn, i just KNEW this > > would be a good match for him. oh well... > > > > my son has the actos but was only on it for a few days very low dose. i > > stopped cause we started the risperdal and my son cannot tolerate many rx meds > > at the same time. i needed my son to be on as less stuff as possible to see > > if this risperdal thing would work. > > > > i believe i read on another list that some parents are using tumeric to work > > on the inflammation... > > > > vicki > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2006 Report Share Posted July 19, 2006 > > > > my son's doc wanted him to try actos to help bring down brain inflammation, > > not to treat viruses. my son's brain is way off balance and is high in > > excitotoxins. i also tried LDN two separate times with horrible results (i tell > > you, i have a tough nut!). from what i have read about ldn, i just KNEW this > > would be a good match for him. oh well... > > > > my son has the actos but was only on it for a few days very low dose. i > > stopped cause we started the risperdal and my son cannot tolerate many rx meds > > at the same time. i needed my son to be on as less stuff as possible to see > > if this risperdal thing would work. > > > > i believe i read on another list that some parents are using tumeric to work > > on the inflammation... > > > > vicki > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2006 Report Share Posted July 19, 2006 > > > > my son's doc wanted him to try actos to help bring down brain inflammation, > > not to treat viruses. my son's brain is way off balance and is high in > > excitotoxins. i also tried LDN two separate times with horrible results (i tell > > you, i have a tough nut!). from what i have read about ldn, i just KNEW this > > would be a good match for him. oh well... > > > > my son has the actos but was only on it for a few days very low dose. i > > stopped cause we started the risperdal and my son cannot tolerate many rx meds > > at the same time. i needed my son to be on as less stuff as possible to see > > if this risperdal thing would work. > > > > i believe i read on another list that some parents are using tumeric to work > > on the inflammation... > > > > vicki > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2006 Report Share Posted July 20, 2006 In a message dated 7/19/2006 9:57:41 PM Pacific Daylight Time, leeandpaul@... writes: I think it's OK to use meds for brian inflamation, but I like to say, "Why is the child's brain > inflamed?"> > I can tell you one reason. Viruses. Herpes virus can cause inflamation on the brain and > can cause autism all by itself. So trying Actos or even steroids to calm the inflamation for > a period of time is fine, IMO, but I would strongly consider a trial of Valtrex with an > antifungal and see if that works on the cause of the inflamation VALTREX WORKED FOR MY SON WELL AND INCREASED HIS COGNITIVE ABILITIES. HOWEVER, ACCORDING TO THE TESTS DONE, MY SON'S BRAIN IS FULL OF EXCITOTOXINS. H IS DOC BELIEVES IT IS CAUSING BRAIN INFLAMMATION. THIS IS AFTER BEING ON VALTREX FOR SOME YEARS. HIS HHV6 LEVELS HAVE COME DOWN TREMENDOUSLY. MY SON HAS ALSO BEEN ON ANTI FUNGALS, BOTH RX AND NATURAL FOR MANY YEARS TOO. HOWEVER, THERE IS STILL A BELIEF THAT THERE IS INFLAMMATION IN THE BRAIN BECAUSE OF THE EXCITOTOXINS. IN THIS CASE, ACTOS WAS RECOMMENDED. WE'LL SEE. HAVENT GIVEN IT A TRY YET. VICKI VICKI Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2006 Report Share Posted July 20, 2006 In a message dated 7/19/2006 9:57:41 PM Pacific Daylight Time, leeandpaul@... writes: I think it's OK to use meds for brian inflamation, but I like to say, "Why is the child's brain > inflamed?"> > I can tell you one reason. Viruses. Herpes virus can cause inflamation on the brain and > can cause autism all by itself. So trying Actos or even steroids to calm the inflamation for > a period of time is fine, IMO, but I would strongly consider a trial of Valtrex with an > antifungal and see if that works on the cause of the inflamation VALTREX WORKED FOR MY SON WELL AND INCREASED HIS COGNITIVE ABILITIES. HOWEVER, ACCORDING TO THE TESTS DONE, MY SON'S BRAIN IS FULL OF EXCITOTOXINS. H IS DOC BELIEVES IT IS CAUSING BRAIN INFLAMMATION. THIS IS AFTER BEING ON VALTREX FOR SOME YEARS. HIS HHV6 LEVELS HAVE COME DOWN TREMENDOUSLY. MY SON HAS ALSO BEEN ON ANTI FUNGALS, BOTH RX AND NATURAL FOR MANY YEARS TOO. HOWEVER, THERE IS STILL A BELIEF THAT THERE IS INFLAMMATION IN THE BRAIN BECAUSE OF THE EXCITOTOXINS. IN THIS CASE, ACTOS WAS RECOMMENDED. WE'LL SEE. HAVENT GIVEN IT A TRY YET. VICKI VICKI Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2006 Report Share Posted July 20, 2006 > > > In a message dated 7/19/2006 9:57:41 PM Pacific Daylight Time, > leeandpaul@... writes: > > I think it's OK to use meds for brian inflamation, but I like to > say, " Why is the child's brain > > inflamed? " > > > > I can tell you one reason. Viruses. Herpes virus can cause > inflamation on the brain and > > can cause autism all by itself. So trying Actos or even steroids > to calm the inflamation for > > a period of time is fine, IMO, but I would strongly consider a > trial of Valtrex with an > > antifungal and see if that works on the cause of the inflamation > > > VALTREX WORKED FOR MY SON WELL AND INCREASED HIS COGNITIVE ABILITIES. > HOWEVER, ACCORDING TO THE TESTS DONE, MY SON'S BRAIN IS FULL OF EXCITOTOXINS. H IS > DOC BELIEVES IT IS CAUSING BRAIN INFLAMMATION. > > THIS IS AFTER BEING ON VALTREX FOR SOME YEARS. HIS HHV6 LEVELS HAVE COME > DOWN TREMENDOUSLY. MY SON HAS ALSO BEEN ON ANTI FUNGALS, BOTH RX AND NATURAL > FOR MANY YEARS TOO. HOWEVER, THERE IS STILL A BELIEF THAT THERE IS > INFLAMMATION IN THE BRAIN BECAUSE OF THE EXCITOTOXINS. > > IN THIS CASE, ACTOS WAS RECOMMENDED. WE'LL SEE. HAVENT GIVEN IT A TRY YET. > > VICKI > > VICKI >What test were given to see this and is excitoxins( found in the food we eat?) What is HHV6 levels? Our Dr. has never mentioned this. Carole Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2006 Report Share Posted July 20, 2006 > > > In a message dated 7/19/2006 9:57:41 PM Pacific Daylight Time, > leeandpaul@... writes: > > I think it's OK to use meds for brian inflamation, but I like to > say, " Why is the child's brain > > inflamed? " > > > > I can tell you one reason. Viruses. Herpes virus can cause > inflamation on the brain and > > can cause autism all by itself. So trying Actos or even steroids > to calm the inflamation for > > a period of time is fine, IMO, but I would strongly consider a > trial of Valtrex with an > > antifungal and see if that works on the cause of the inflamation > > > VALTREX WORKED FOR MY SON WELL AND INCREASED HIS COGNITIVE ABILITIES. > HOWEVER, ACCORDING TO THE TESTS DONE, MY SON'S BRAIN IS FULL OF EXCITOTOXINS. H IS > DOC BELIEVES IT IS CAUSING BRAIN INFLAMMATION. > > THIS IS AFTER BEING ON VALTREX FOR SOME YEARS. HIS HHV6 LEVELS HAVE COME > DOWN TREMENDOUSLY. MY SON HAS ALSO BEEN ON ANTI FUNGALS, BOTH RX AND NATURAL > FOR MANY YEARS TOO. HOWEVER, THERE IS STILL A BELIEF THAT THERE IS > INFLAMMATION IN THE BRAIN BECAUSE OF THE EXCITOTOXINS. > > IN THIS CASE, ACTOS WAS RECOMMENDED. WE'LL SEE. HAVENT GIVEN IT A TRY YET. > > VICKI > > VICKI >What test were given to see this and is excitoxins( found in the food we eat?) What is HHV6 levels? Our Dr. has never mentioned this. Carole Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 21, 2006 Report Share Posted July 21, 2006 Vicki: I too would like to know what tests the doctor relied upon to state that your son’s brain has excess exitotoxins, was it blood, urine, amino acids? I am really curious because my son’s neurologist said that there was really know way to accurately test this as blood and urine does not necessarily represent what levels are in the CNS, but if there are other biological markers that show a likelihood that this is the case, I would love to know what they are….I have always assumed this was the case with my son as well…. Re: Actose - carole > > > In a message dated 7/19/2006 9:57:41 PM Pacific Daylight Time, > leeandpaul@... writes: > > I think it's OK to use meds for brian inflamation, but I like to > say, " Why is the child's brain > > inflamed? " > > > > I can tell you one reason. Viruses. Herpes virus can cause > inflamation on the brain and > > can cause autism all by itself. So trying Actos or even steroids > to calm the inflamation for > > a period of time is fine, IMO, but I would strongly consider a > trial of Valtrex with an > > antifungal and see if that works on the cause of the inflamation > > > VALTREX WORKED FOR MY SON WELL AND INCREASED HIS COGNITIVE ABILITIES. > HOWEVER, ACCORDING TO THE TESTS DONE, MY SON'S BRAIN IS FULL OF EXCITOTOXINS. H IS > DOC BELIEVES IT IS CAUSING BRAIN INFLAMMATION. > > THIS IS AFTER BEING ON VALTREX FOR SOME YEARS. HIS HHV6 LEVELS HAVE COME > DOWN TREMENDOUSLY. MY SON HAS ALSO BEEN ON ANTI FUNGALS, BOTH RX AND NATURAL > FOR MANY YEARS TOO. HOWEVER, THERE IS STILL A BELIEF THAT THERE IS > INFLAMMATION IN THE BRAIN BECAUSE OF THE EXCITOTOXINS. > > IN THIS CASE, ACTOS WAS RECOMMENDED. WE'LL SEE. HAVENT GIVEN IT A TRY YET. > > VICKI > > VICKI >What test were given to see this and is excitoxins( found in the food we eat?) What is HHV6 levels? Our Dr. has never mentioned this. Carole Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 21, 2006 Report Share Posted July 21, 2006 Vicki: I too would like to know what tests the doctor relied upon to state that your son’s brain has excess exitotoxins, was it blood, urine, amino acids? I am really curious because my son’s neurologist said that there was really know way to accurately test this as blood and urine does not necessarily represent what levels are in the CNS, but if there are other biological markers that show a likelihood that this is the case, I would love to know what they are….I have always assumed this was the case with my son as well…. Re: Actose - carole > > > In a message dated 7/19/2006 9:57:41 PM Pacific Daylight Time, > leeandpaul@... writes: > > I think it's OK to use meds for brian inflamation, but I like to > say, " Why is the child's brain > > inflamed? " > > > > I can tell you one reason. Viruses. Herpes virus can cause > inflamation on the brain and > > can cause autism all by itself. So trying Actos or even steroids > to calm the inflamation for > > a period of time is fine, IMO, but I would strongly consider a > trial of Valtrex with an > > antifungal and see if that works on the cause of the inflamation > > > VALTREX WORKED FOR MY SON WELL AND INCREASED HIS COGNITIVE ABILITIES. > HOWEVER, ACCORDING TO THE TESTS DONE, MY SON'S BRAIN IS FULL OF EXCITOTOXINS. H IS > DOC BELIEVES IT IS CAUSING BRAIN INFLAMMATION. > > THIS IS AFTER BEING ON VALTREX FOR SOME YEARS. HIS HHV6 LEVELS HAVE COME > DOWN TREMENDOUSLY. MY SON HAS ALSO BEEN ON ANTI FUNGALS, BOTH RX AND NATURAL > FOR MANY YEARS TOO. HOWEVER, THERE IS STILL A BELIEF THAT THERE IS > INFLAMMATION IN THE BRAIN BECAUSE OF THE EXCITOTOXINS. > > IN THIS CASE, ACTOS WAS RECOMMENDED. WE'LL SEE. HAVENT GIVEN IT A TRY YET. > > VICKI > > VICKI >What test were given to see this and is excitoxins( found in the food we eat?) What is HHV6 levels? Our Dr. has never mentioned this. Carole Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2006 Report Share Posted July 25, 2006 because my son is such a "tough nut" i have always done lots of research and testing. trying to find answers here. his HHV6 levels were out of control some yrs ago. but, with valtrex for a while, they are looking pretty good. right now, im concentrating on the metals and other viruses. most other tests look decent. vicki Quote Link to comment Share on other sites More sharing options...
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