Re: Ursodeoxycholic Acid Helpful in Biliary Cirrhosis

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What is this substance and what things is it found in? Is it a singular substance? Sharonelizabethnv1 <elizabethnv1@...> wrote: Ursodeoxycholic Acid Helpful in Biliary CirrhosisNEW YORK (Reuters Health) Aug 14 - A meta-analysis of studies involving more than a thousand subjects indicates that long-term treatment with ursodeoxycholic acid is beneficial in patients with primary biliary cirrhosis and may reduce the need for liver transplantation, according to Chinese researchers.

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From what I have read is that Ursodeoxcholic acid is a naturally made chemical in the bile . Here is some more information about it .. Ursodeoxcholic acid is also chemiclly made

Ursodeoxycholic Acid

Background and Pharmacology Ursodeoxycholic acid is a highly hydrophilic, nontoxic bile acid (Figure 1). Ursodeoxycholic acid has been shown to protect cell membranes (in vitro) and therefore may

Ursodeoxycholic Acid

Background and Pharmacology Ursodeoxycholic acid is a highly hydrophilic, nontoxic bile acid (Figure 1). Ursodeoxycholic acid has been shown to protect cell membranes (in vitro) and therefore may prevent hepatocyte damage. Further, UDCA may have immunomodulatory effects. The agent is extensively used for the treatment of gallstones and, more recently, for the treatment of primary biliary cirrhosis. Although UDCA treatment improves serum aminotransferase levels in autoimmune hepatitis and in the hepatic dysfunction associated with total parenteral nutrition, it does not alter the natural history of these conditions. The results of studies employing UDCA monotherapy and UDCA in combination with alpha interferon as therapy for hepatitis C are summarized in Table 2.[18-23] Ursodeoxycholic Acid Monotherapy In chronic hepatitis C patients treated with UDCA, gamma-glutamyl transpeptidase [GGT] and ALT liver enzymes were improved.[24-26] However, in a case-control study of 15 hepatitis C patients treated with UDCA (600 mg daily for 6 months), no biochemical or virologic responses were observed.[27] Additionally, in a multicenter study conducted by Takano et al,[18] 57 alpha interferon-naive patients with chronic hepatitis C were randomized to one of three daily UDCA regimens: 150 mg, 600 mg, or 900 mg. In Weeks 12 and 16 of therapy, patients administered 600-mg and 900-mg doses exhibited significant reductions in ALT (up to 26% and 25.5% of patients, respectively) and in GGT (40.5% and 45.6% of patients, respectively), but no virologic response was noted during the study. The fraction of UDCA in total bile acid increased in a dose-dependent manner. prevent hepatocyte damage. Further, UDCA may have immunomodulatory effects. The agent is extensively used for the treatment of gallstones and, more recently, for the treatment of primary biliary cirrhosis. Although UDCA treatment improves serum aminotransferase levels in autoimmune hepatitis and in the hepatic dysfunction associated with total parenteral nutrition, it does not alter the natural history of these conditions. The results of studies employing UDCA monotherapy and UDCA in combination with alpha interferon as therapy for hepatitis C are summarized in Table 2.[18-23]

Ursodeoxycholic Acid Monotherapy In chronic hepatitis C patients treated with UDCA, gamma-glutamyl transpeptidase [GGT] and ALT liver enzymes were improved.[24-26] However, in a case-control study of 15 hepatitis C patients treated with UDCA (600 mg daily for 6 months), no biochemical or virologic responses were observed.[27] Additionally, in a multicenter study conducted by Takano et al,[18] 57 alpha interferon-naive patients with chronic hepatitis C were randomized to one of three daily UDCA regimens: 150 mg, 600 mg, or 900 mg. In Weeks 12 and 16 of therapy, patients administered 600-mg and 900-mg doses exhibited significant reductions in ALT (up to 26% and 25.5% of patients, respectively) and in GGT (40.5% and 45.6% of patients, respectively), but no virologic response was noted during the study. The fraction of UDCA in total bile acid increased in a dose-dependent manner.

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URSODEOXYCHOLIC ACID IS A SYNTHETIC BILE ACID, (URSO) NORMALLY PRODUCED BY THE GALLBLADER. CHECK MEDICAL ENCYCLOPIDIA OR RX .COM FOR MORE INFO. THE CHINESE HAVE BEEN USING THIS FOR LIVER HEALTH FOR MANY YEARS .(BLACK BEAR GALLBLADDERS AND LIVERS) ARE AN IMPORTANT PART OF SOME OF THEIR CULTURES HOLISTIC MEDICINE.

> Ursodeoxycholic Acid Helpful in Biliary Cirrhosis> > > > > NEW YORK (Reuters Health) Aug 14 - A meta-analysis of studies > involving more than a thousand subjects indicates that long-term > treatment with ursodeoxycholic acid is beneficial in patients with > primary biliary cirrhosis and may reduce the need for liver > transplantation, according to Chinese researchers.> > > > ---------------------------------> All-new - Fire up a more powerful email and get things done faster.>