Re: [Hepatitis C}basic info on drugs in the pipeline

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Last updated 11 APRIL 2006 Drugs specific for Hepatitis C Company Drug Type Development Pre Clinical Clinical Phase I Clinical Phase II Clinical Phase III NDA Idenix NM283 Polymerase inhibitor xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Vertex Protease Inhibitor VX950 xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Schering Protease InhibitorSCH503034 xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Intercell Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx AVI BioPharma Antisense xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx VGX Pharma VGX-410C IRES inhib. xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Innogenetics Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Chiron / CSL Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx XTL XTL-6865 (Ab68 & Ab65)Monoclonal antibody xxxxxxxxxxx xxxxxxxx xxxx Viro Pharma / Wyeth HCV-796 Polymerase inhibitor xxxxxxxxxxx xxxxxxxx xxxx Gilead / Achillion Protease Inhibitor ACH806 GS9132 xxxxxxxxxxx xxxxxxxx xxxx GlobeImmune GI

5005 Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxx Aethlon Medical Hemopurifier xxxxxxxxxxx xxxxxxxx xxxx Sirna Therapeutics RNAi (RNA interfence) xxxxxxxxxxx xxxxxxxx mid 2006 Tripep / Inovio TherapeuticVaccine xxxxxxxxxxx xxxxxxxx late 2006 Benitec RNA interference xxxxxxxxxxx xxxxxxxx late 2006 Roche / Pharmasset PSI-6130 nucleoside polymerase inhibitor xxxxxxxxxxx xxxxxxxx 2006 XTL XTL2125 polymerase

inhibitor xxxxxxxxxxx xxxxxxxx Intermune / Array Biopharma Protease inhibitor xxxxxxxxxxx xxxx Arrow Therapeutics A-831 NS5aInhibitor xxxxxxxxxxx xxxx Biocryst Polymerase inhibitor xxxxxxxxxxx xxxx Genelabs GL59728 & GL60667 Non-nucleoside & nucleosidepolymerase inhib. xxxxxxxxxxx xxxx ViRex Medical Hepavaxx CTheraputicVaccine xxxxxxxxxxx xxxx Idera 2125 xxxxxxxxxxx xxxx GenPhar Vaccine xxxxxxxxxxx xxxx Rigel Pharm new drug xxxxxx Migenix non-nucleoside xxxxxx Merk /

Metabasis small molecule xxxxxx Isis / Merk ???? xxxx?? PTC / Schering IRES inhib xxxxxx Vertex Helicase inhibitor xxxxxx Trimeris Fusion inhibitor xxxxxx Gilead Protease, polymerase inhib xxxxxx Medivir / Tibotec Protease inhibitor xxxxxx Medivir / Roch Polymerase inhibor xxxxxx Chiron / Enanta Protease inhib xxxxxx Cetek small molecule xxxxxx Glaxo Wellcome ???? xx?? Immusol / Novartis Target disc. xxxx?? Argos Theraputics Therapeutic vaccine xx? Tibotec polymerase inhib. xxxx Alnylam RNAi xx Existing drugs and drugs not specific to the HCV being tested for Hepatitis C & Drugs for related conditions Migenix MX3235 Celgosivir alpha-glucosidase I inhibitor xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Human Genome Sciences Albuferon (interferon

/albuminfusion) xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Coley Pharm. ActilonTLR9 agonist xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Intarcia Omega Interferon xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx NABI Polyclonal antibody Civacir xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Anadys / Novartis ANA975 prodrugof TLR7 antagonist xxxxxxxxxxx xxxxxxxx xxxx Peregrine Pharm Tarvacin xxxxxxxxxxx xxxxxxxx xxxx Enzo Biochem Immune

Regulator xxxxxxxxxxx xxxxxxxx xxxx Enzo Biochem Broad spectrum antigen immune regulation xxxxxxxxxxx xxxxxxxx xxxx Immunomedics IMMU 105 xxxxxxxxxxx xxxxxxxx xxxx Novelos NOV-205 xxxxxxxxxxx xxxxxxxx 2006 Anadys AN 025-1 xxxxxxxx

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thanks tim,, excellent info!Hillbilly Tim <knoxweb1@...> wrote: Last updated 11 APRIL 2006 Drugs specific for Hepatitis C Company Drug Type Development Pre Clinical Clinical Phase I Clinical Phase II Clinical Phase III NDA Idenix NM283 Polymerase inhibitor xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Vertex Protease Inhibitor VX950 xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Schering Protease InhibitorSCH503034 xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Intercell Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx AVI BioPharma Antisense xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx VGX Pharma VGX-410C IRES

inhib. xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Innogenetics Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx Chiron / CSL Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxxxxx xxxx XTL XTL-6865

(Ab68 & Ab65)Monoclonal antibody xxxxxxxxxxx xxxxxxxx xxxx Viro Pharma / Wyeth HCV-796 Polymerase inhibitor xxxxxxxxxxx xxxxxxxx xxxx Gilead / Achillion Protease Inhibitor ACH806 GS9132 xxxxxxxxxxx xxxxxxxx xxxx GlobeImmune GI 5005 Therapeutic vaccine xxxxxxxxxxx xxxxxxxx xxxx Aethlon Medical Hemopurifier xxxxxxxxxxx xxxxxxxx xxxx Sirna Therapeutics RNAi (RNA interfence) xxxxxxxxxxx xxxxxxxx mid 2006 Tripep / Inovio TherapeuticVaccine xxxxxxxxxxx xxxxxxxx late 2006 Benitec RNA interference xxxxxxxxxxx xxxxxxxx late 2006 Roche / Pharmasset PSI-6130 nucleoside polymerase inhibitor xxxxxxxxxxx xxxxxxxx 2006 XTL XTL2125 polymerase inhibitor xxxxxxxxxxx xxxxxxxx Intermune / Array Biopharma Protease inhibitor xxxxxxxxxxx xxxx Arrow Therapeutics A-831 NS5aInhibitor xxxxxxxxxxx xxxx Biocryst Polymerase inhibitor xxxxxxxxxxx xxxx Genelabs GL59728 & GL60667 Non-nucleoside & nucleosidepolymerase inhib. xxxxxxxxxxx xxxx ViRex Medical Hepavaxx CTheraputicVaccine xxxxxxxxxxx xxxx Idera 2125 xxxxxxxxxxx xxxx GenPhar Vaccine xxxxxxxxxxx xxxx Rigel

Pharm new drug xxxxxx Migenix non-nucleoside xxxxxx Merk / Metabasis small molecule xxxxxx Isis / Merk ???? xxxx?? PTC / Schering

IRES inhib xxxxxx Vertex Helicase inhibitor xxxxxx Trimeris Fusion inhibitor xxxxxx Gilead Protease, polymerase inhib xxxxxx Medivir / Tibotec Protease inhibitor xxxxxx Medivir / Roch Polymerase inhibor xxxxxx Chiron / Enanta Protease inhib xxxxxx Cetek small molecule xxxxxx Glaxo Wellcome ???? xx?? Immusol / Novartis Target disc. xxxx?? Argos Theraputics Therapeutic vaccine xx? Tibotec polymerase inhib. xxxx Alnylam RNAi xx Existing drugs and drugs not specific to the HCV being tested for Hepatitis C & Drugs for related conditions Migenix MX3235 Celgosivir alpha-glucosidase

I inhibitor xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Human Genome Sciences Albuferon (interferon

/albuminfusion) xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Coley Pharm. ActilonTLR9 agonist xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Intarcia Omega Interferon xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx NABI Polyclonal antibody Civacir xxxxxxxxxxx xxxxxxxx xxxxxxx xxxxx Anadys / Novartis ANA975 prodrugof TLR7 antagonist xxxxxxxxxxx xxxxxxxx xxxx Peregrine Pharm Tarvacin xxxxxxxxxxx xxxxxxxx xxxx Enzo Biochem Immune

Regulator xxxxxxxxxxx xxxxxxxx xxxx Enzo Biochem Broad spectrum antigen immune regulation xxxxxxxxxxx xxxxxxxx xxxx Immunomedics IMMU 105 xxxxxxxxxxx xxxxxxxx xxxx Novelos NOV-205 xxxxxxxxxxx xxxxxxxx 2006 Anadys AN 025-1 xxxxxxxx New Messenger with Voice. Call regular phones from your PC and save big. Jackie