Re: OLE/ Virastop trial ( and Stan)

April 19, 2006

> One other thing to note, my kids' supplementation schedule changed

> entirely after the healing regression. Their bodies were

> different. The very things that used to calm them down agitated

> them. I do not know if others have experienced this, but it was

> weird. It was almost like starting over on supplementation for us.

>

Hi (remember me Stan?),

The same things seem to have happened after we did 3 months of

Valtrex at a reduced dose for our son. He could no longer tolearte

folinic acid and TMG while taking TD-MB12 after having taken them for

apprx 9 months. We switched to nasal MB-12 and had to do it WITHOUT

the folinic acid and then take away the TMG and Folinic Acid as

well. He is a normally active little guy, never hyper with minor

stims that come and go, but this combo was making him bounce off the

walls and had him super-duper stimmy!

We are getting ready to start another " round " of Valtrex, but because

he is highly sensitive to some supplements/meds (i.e. Valtrex) after

having done the standard protocol 2x per day for several weeks, we

had to bring it down to 1/4 of the dose 1x per day and slowly build

up to the 1x per day dose which was where he was more manageable. Oh,

and yes, he was on Diflucan most of the time, since I realized some

of those signs were due to yeast. While he was on the standard

dosing protocol, he was pretty UNBEREABLE (and believe me, I am super

patient and can take anything...). He had major stims, defiance, was

very hyper, would hit anyone, not follow directions, was very

sensory, visual stims, and OCD behaviors that kept increasing and

increasing, etc. Now, to make this very clear, this was not his

normal behavior pre-Valtrex, but when he takes something he seemingly

cannot tolerate, he usually reacts by becoming stimmy and hyper. So

after " riding it out " while taking the 2x per day dose for 5-6 weeks,

we took him down to the reduced dosage and things were better, well

at least more manageable... Things were getting complicated at home,

but mostly at school, so after finishing the initial Valtrex we had

in Nov. 05, we decided to wait a few months until re-starting. We

are now getting ready to start in a matter of a few days and I am

dreading the effects, (mostly because of school), but I guess, I will

start slow and get him to the 1x per day dose and keep him there for

a while before I increase it. I figured, better get some Valtrex in

at a slower rate than none. He should still benefit from it--it just

may take longer to see the desired results. He was a definite

responder to Valtrex and is unvaccinated but yet has ASD and Apraxia

of Speech. The Apraxia is the most problematic for him. After

Valtrex, he is now clearer, can speak in full sentences, and even

started asking WH questions, although not often but still, he did it

spontenously. He had a major fine-motor regression as well, but

seems to finally have overcome 75% of it by now. So, in re-starting

Valtrex in a few days (we started Diflucan 3 days ago), I am hoping

to see more gains in these areas because he is so, so close to

becoming " recovered " , but we feel we have not found that missing

piece to get him over this " obstacle " . Expressive speech and fine

motor are big ones for him, areas that need major " clean up " , ASD is

more secondary. In fact, I am currently taking OLE (which I knew

about over a yar and a half ago but never did until I would get sick,

if at all, and would take it temporarily and then forget about it).

So now, I have been taking it for close to a week, and I can say I

don't feel too great: tired/sluggish (unusual for me), a sore throat

too. This all started after taking OLE for 1 day at 2 caps 2x per

day. I was taking 2 caps 2x per day but decided to reduce it (as I

was feeling worse) to 1 cap 2x per day and see how it goes and adjust

as needed. Although I have been pretty healthy most of my life, I

know I must have a big viral issue, hence my son developing ASD, so

we'll see what happens.

Mari

April 19, 2006