Re: family history of breast cancer and spiro?

[Guest guest]

Can you give the source of this information? Some here would agree with this.

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> Are there any articles or has any had an experience with spiro creating

conditions to promote breast cancer. have read articles that patients with

family history of breast cancer should avoid spiro, but patient was not being

treated for PA.

>

[Guest guest]

http://www.ncbi.nlm.nih.gov/pubmed/2357784

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> > Are there any articles or has any had an experience with spiro creating

conditions to promote breast cancer. have read articles that patients with

family history of breast cancer should avoid spiro, but patient was not being

treated for PA.

> >

>

[Guest guest]

here are a few other links noted from research i have done:

http://www.ncbi.nlm.nih.gov/pubmed/15108046

http://www.ncbi.nlm.nih.gov/pubmed/2197584

http://www.ncbi.nlm.nih.gov/pubmed/7114041

copied from a forum disscussion

http://community.breastcancer.org/ : (NOT my expeerience)

" I was on spironolactone for many years, and I too wondered if my being on it

had any impact on my developing breast cancer. To me, it seems like the

spironolactone definitely wouldn't help, at least in theory. If it's going to

block the adrogens, then in my logical mind, it seems like more of the estrogen

would be unopposed, and my tumor was highly ER+. I have no family history, at

least that I know, with breast cancer, so while I can't say for sure that

spironolactone caused it, I would think that it definitely didn't help. Just my

two cents....

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> > > Are there any articles or has any had an experience with spiro creating

conditions to promote breast cancer. have read articles that patients with

family history of breast cancer should avoid spiro, but patient was not being

treated for PA.

> > >

> >

>

[Guest guest]

I have a very strong concern, as my maternal aunt has battled breast cancer two

times ( and is a survivor), as well as my mother( a one-time survivor)

I am a female, 43yrsold. possible dx of hyperaldosteronism...

> > > >

> > > > Are there any articles or has any had an experience with spiro creating

conditions to promote breast cancer. have read articles that patients with

family history of breast cancer should avoid spiro, but patient was not being

treated for PA.

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> > >

> >

>

[Guest guest]

do a pub med to get best info.Not aware of any good studies. CE Grim MDOn Jul 31, 2012, at 8:15 AM, martyd3811 wrote:

Are there any articles or has any had an experience with spiro creating conditions to promote breast cancer. have read articles that patients with family history of breast cancer should avoid spiro, but patient was not being treated for PA.

[Guest guest]

seems that a recently published article at pub med

sites a study of women over 55- no increased risk in patients with no family

history... not sure what the conclusion is for women that do have a family

history? since conclusion is so specific...

http://www.ncbi.nlm.nih.gov/pubmed/22797844

>

> > Are there any articles or has any had an experience with spiro creating

conditions to promote breast cancer. have read articles that patients with

family history of breast cancer should avoid spiro, but patient was not being

treated for PA.

> >

> >

>

[Guest guest]

And we are not treating excess hair. They use up to 200 mg a day.CE Grim MDOn Jul 31, 2012, at 8:32 AM, martyd3811 wrote:

http://www.ncbi.nlm.nih.gov/pubmed/2357784

> >

> > Are there any articles or has any had an experience with spiro creating conditions to promote breast cancer. have read articles that patients with family history of breast cancer should avoid spiro, but patient was not being treated for PA.

> >

>

[Guest guest]

These are useful references and should be put in a folder in our files re: breast cancer and sprio.The first is s single case report.The second is interesting but may be confounded by an incidental Dx of Ca breast detected due to breast tenderness due to spiro. The 3rd is from 1982 and should be repeated with the much larger data bases available now. As I recall another followup study from Boston looked at the reserpine association and found no significant one. This made the news back then as reserpine was a commonly used BP med and a good cheap one.In none of these do we know the denominator ie folks taking spiro but no breast problems.Thanks,CE Grim MDOn Jul 31, 2012, at 8:50 AM, martyd3811 wrote:

here are a few other links noted from research i have done:

http://www.ncbi.nlm.nih.gov/pubmed/15108046

http://www.ncbi.nlm.nih.gov/pubmed/2197584

http://www.ncbi.nlm.nih.gov/pubmed/7114041

copied from a forum disscussion

http://community.breastcancer.org/ : (NOT my expeerience)

"I was on spironolactone for many years, and I too wondered if my being on it had any impact on my developing breast cancer. To me, it seems like the spironolactone definitely wouldn't help, at least in theory. If it's going to block the adrogens, then in my logical mind, it seems like more of the estrogen would be unopposed, and my tumor was highly ER+. I have no family history, at least that I know, with breast cancer, so while I can't say for sure that spironolactone caused it, I would think that it definitely didn't help. Just my two cents....

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> > > Are there any articles or has any had an experience with spiro creating conditions to promote breast cancer. have read articles that patients with family history of breast cancer should avoid spiro, but patient was not being treated for PA.

> > >

> >

>

[Guest guest]

So I would DASH to the max (and document with spot urine Na, K, creatinine) before trying any drugs for BP/low K ever linked to breast cancer. May want to see if there are any places nearby who are doing gene testing for familial Breast CA risk. CE Grim MDOn Jul 31, 2012, at 8:53 AM, martyd3811 wrote:

I have a very strong concern, as my maternal aunt has battled breast cancer two times ( and is a survivor), as well as my mother( a one-time survivor)

I am a female, 43yrsold. possible dx of hyperaldosteronism...

> > > >

> > > > Are there any articles or has any had an experience with spiro creating conditions to promote breast cancer. have read articles that patients with family history of breast cancer should avoid spiro, but patient was not being treated for PA.

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[Guest guest]

This is an excellent new article and the complete article can be downloaded for free thru pubmed. Recommend you do this and then upload it to our files re spiro and breast CAGood job!CE Grim MDOn Jul 31, 2012, at 9:48 AM, martyd3811 wrote:

seems that a recently published article at pub med

sites a study of women over 55- no increased risk in patients with no family history... not sure what the conclusion is for women that do have a family history? since conclusion is so specific...

http://www.ncbi.nlm.nih.gov/pubmed/22797844

>

> > Are there any articles or has any had an experience with spiro creating conditions to promote breast cancer. have read articles that patients with family history of breast cancer should avoid spiro, but patient was not being treated for PA.

> >

> >

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[Guest guest]

I did a quick review of the articles and didn't see any positive conclusions

(many were older articles). I would suspect if there were any current issues

they would look at it like they did in that 1.25M PTN over 55 study. Now with

that said, I wouldn't hesitate to discuss your concerns with your doctor and

investigte using Eplerenone, it's working well for me!

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> > > Are there any articles or has any had an experience with spiro creating

conditions to promote breast cancer. have read articles that patients with

family history of breast cancer should avoid spiro, but patient was not being

treated for PA.

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[Guest guest]

i am not sure how to create a folder ... if someone knows how to make the folder

and add to the files that would be great. thanks.

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> > > > > Are there any articles or has any had an experience with spiro

creating conditions to promote breast cancer. have read articles that patients

with family history of breast cancer should avoid spiro, but patient was not

being treated for PA.

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