Re: Re: Blood Pressure lower off of Spiro? Why?

[Guest guest]

http://www.livestrong.com/article/410475-vitamin-d-interaction-with-prescrip

tion-drugs/

| Blood Pressure lower off of Spiro? Why?

|> |

|> |I have been off Spiro for 1 week now leading up to an AVS procedure.

|> |My blood pressure went up for the first couple of days, but now it

|> |has settled

|> at an

|> |average of 118/78! I ate high salt on Saturday due to my daughter's

B-day.

|> No

|> |budge on the blood pressure on Sunday or today. This morning my

|> |readings were 118/78, 108/76, and 112/79.

|> |

|> |It seems that my BP has been lower off of Spiro vs when I took 50mg

|> |per

|> day.

|> |Is there an explanation for this? My diet has been almost exactly

|> |the

|> same. In

|> |addition to not taking Spiro, I discontinued 1000 IU Vitamin D each day.

|> |

|> |I am now wondering why BP is normal. I am wondering if I even have

|> |PA at

|> all.

|> |Do I still need an AVS? If I have PA, why would my BP be lower off

|> |of

|> Spiro?

|> |

|> |When I e-mailed my doctor, he shrugged it off and just told me to be

|> thankful

|> |that my BP is controlled off of Spiro. He told me to go through with

|> |the

|> AVS to

|> |determine if surgery would be a cure.

|> |

|> |I am confused and expected BP to skyrocket off of the meds.

|> |

|> |

|> |35 male. Diagnosed 04/2011. AVS scheduled 08/23. Tested for GRA -

|> |Negative.

|> |

|> |

|> |

|> |------------------------------------

|> |

|> |

[Guest guest]

Note article from Saudi Arabia most impressive "results" were in women who are always "covered". As far as I know there is no proper trial that clearly demonstrates that people live longer or healthier when taking Vit D than when not given Vit D.Some ongoing. Institue of Medicine has made similar conclusions as I recall.CE Grim MDOn Jul 30, 2012, at 2:46 PM, wrote:

JW, they tested my Vit D at NIH And Dxed me Hypovitaminosis D when it came back at 18, range 20-50. They explained a couple of things. When the decision to supplement foods they underestimated the requirement. We also tend to spend less time I the sun as a society and many of us are not in an area where sun shines abundantly! When we are in the sun we often use sunscreen, which he encouraged, but that and darker skin color tends to reduce the absorption.As I understand it, the body stores Vit D so they RXed 50,000UNIT of ergocaliferol (vit d2) weekly for 8 weeks and retest. When level gets to 40 they suggested a maintenance dose of 50,000 every other week or a daily dose to be determined to keep in mid range. I just tested after 8 weeks and it was 23.7 so I have a ways to go! (The wife suggested I take my shirt off and go mow the lawn but with my "Spiro Boobs" I'd probably get arrested!) Here is a recent article that sheds some light on the subject:

http://www.cardiab.com/content/pdf/1475-2840-11-85.pdfHope that helps, I demanded my wife's PCP test her and guess what - she is low too and she loves her flower gardens! (Do I have to teach these doctors everything?) …Jhn.> > |>> > |> I found that vit-D interferes with calcium channels of kidneys> > |> blocking the effects of some medications like amlodipine...or perhaps> > |> to some degree Spiro...If you wait another 3 weeks you will know if bp> > |> is shooting up without Spiro or not...but lucky you, 118/78 was when I> > was> > |20 !> > |>> > |> Max, 62M> > |>> > |> | Blood Pressure lower off of Spiro? Why?>

[Guest guest]

Can someone do a pubmed search on the Vit D interactions say with CCBs?No sure of the site you sent us to.CE Grim MDOn Jul 30, 2012, at 11:53 AM, MedStat wrote:

http://www.livestrong.com/article/410475-vitamin-d-interaction-with-prescrip

tion-drugs/

| Blood Pressure lower off of Spiro? Why?

|> |

|> |I have been off Spiro for 1 week now leading up to an AVS procedure.

|> |My blood pressure went up for the first couple of days, but now it

|> |has settled

|> at an

|> |average of 118/78! I ate high salt on Saturday due to my daughter's

B-day.

|> No

|> |budge on the blood pressure on Sunday or today. This morning my

|> |readings were 118/78, 108/76, and 112/79.

|> |

|> |It seems that my BP has been lower off of Spiro vs when I took 50mg

|> |per

|> day.

|> |Is there an explanation for this? My diet has been almost exactly

|> |the

|> same. In

|> |addition to not taking Spiro, I discontinued 1000 IU Vitamin D each day.

|> |

|> |I am now wondering why BP is normal. I am wondering if I even have

|> |PA at

|> all.

|> |Do I still need an AVS? If I have PA, why would my BP be lower off

|> |of

|> Spiro?

|> |

|> |When I e-mailed my doctor, he shrugged it off and just told me to be

|> thankful

|> |that my BP is controlled off of Spiro. He told me to go through with

|> |the

|> AVS to

|> |determine if surgery would be a cure.

|> |

|> |I am confused and expected BP to skyrocket off of the meds.

|> |

|> |

|> |35 male. Diagnosed 04/2011. AVS scheduled 08/23. Tested for GRA -

|> |Negative.

|> |

|> |

|> |

|> |------------------------------------

|> |

|> |

[Guest guest]

Do you have BP tracking as far back as you can go with meds. I attach an excel sheet for this if you want to try.See lab data sheet.CE Grim MD

On Jul 30, 2012, at 1:33 PM, crzylnebkr wrote:

I am eating almost the exact same menu. I have been eating pretty well even on Sprio and keeping Sodium fairly low. I had a lot of salt Saturday and had no movement in BP. On the Sprio when I had a bad salt day my BP would suffer for 1 to 2 days after.

>

> > I have been off Spiro for 1 week now leading up to an AVS procedure. My blood pressure went up for the first couple of days, but now it has settled at an average of 118/78! I ate high salt on Saturday due to my daughter's B-day. No budge on the blood pressure on Sunday or today. This morning my readings were 118/78, 108/76, and 112/79.

> >

> > It seems that my BP has been lower off of Spiro vs when I took 50mg per day. Is there an explanation for this? My diet has been almost exactly the same. In addition to not taking Spiro, I discontinued 1000 IU Vitamin D each day.

> >

> > I am now wondering why BP is normal. I am wondering if I even have PA at all. Do I still need an AVS? If I have PA, why would my BP be lower off of Spiro?

> >

> > When I e-mailed my doctor, he shrugged it off and just told me to be thankful that my BP is controlled off of Spiro. He told me to go through with the AVS to determine if surgery would be a cure.

> >

> > I am confused and expected BP to skyrocket off of the meds.

> >

> >

> > 35 male. Diagnosed 04/2011. AVS scheduled 08/23. Tested for GRA - Negative.

> >

> >

>

1 of 1 File(s)

Master Data File 120728.0.xlsx

[Guest guest]

Only if you wear you white fur coat when you come to see me.Or wear you hair in Dreds if you want to be treated as a hydra.CE Grim MDOn Jul 30, 2012, at 7:42 PM, wrote:

Since you don't trust the info from the Saudi's , is a Rat better? Here is wht you requested:

Results: 3

1.

The localization of PGE2 receptor subtypes in rat retinal cultures and the neuroprotective effect of the EP2 agonist butaprost.

Andrade da Costa BL, Kang KD, Rittenhouse KD, Osborne NN.Neurochem Int. 2009 Sep;55(4):199-207. Epub 2009 Mar 5.

PMID:

19524109

[PubMed - indexed for MEDLINE] Related citations

2.

Vascular calcification and osteoporosis--from clinical observation towards molecular understanding.

Hofbauer LC, Brueck CC, Shanahan CM, Schoppet M, Dobnig H.Osteoporos Int. 2007 Mar;18(3):251-9. Epub 2006 Dec 7. Review.

PMID:

17151836

[PubMed - indexed for MEDLINE] Related citations

3.

Hormonal factors from the mammalian pineal gland interfere with cell development in Hydra.

Müller WA, Bartsch C, Bartsch H, Maidonis I, Bayer E.Int J Dev Biol. 1998 Sep;42(6):821-4.

PMID:

9727839

[PubMed - indexed for MEDLINE] Free ArticleRelated citations > > |>> > |> I found that vit-D interferes with calcium channels of kidneys> > |> blocking the effects of some medications like amlodipine...or perhaps> > |> to some degree Spiro...If you wait another 3 weeks you will know if bp> > |> is shooting up without Spiro or not...but lucky you, 118/78 was when I> > was> > |20 !> > |>> > |> Max, 62M> > |>> > |> | Blood Pressure lower off of Spiro? Why?> > |> |> > |> |I have been off Spiro for 1 week now leading up to an AVS procedure.> > |> |My blood pressure went up for the first couple of days, but now it> > |> |has settled> > |> at an> > |> |average of 118/78! I ate high salt on Saturday due to my daughter's> > B-day.> > |> No> > |> |budge on the blood pressure on Sunday or today. This morning my> > |> |readings were 118/78, 108/76, and 112/79.> > |> |> > |> |It seems that my BP has been lower off of Spiro vs when I took 50mg> > |> |per> > |> day.> > |> |Is there an explanation for this? My diet has been almost exactly> > |> |the> > |> same. In> > |> |addition to not taking Spiro, I discontinued 1000 IU Vitamin D each day.> > |> |> > |> |I am now wondering why BP is normal. I am wondering if I even have> > |> |PA at> > |> all.> > |> |Do I still need an AVS? If I have PA, why would my BP be lower off> > |> |of> > |> Spiro?> > |> |> > |> |When I e-mailed my doctor, he shrugged it off and just told me to be> > |> thankful> > |> |that my BP is controlled off of Spiro. He told me to go through with> > |> |the> > |> AVS to> > |> |determine if surgery would be a cure.> > |> |> > |> |I am confused and expected BP to skyrocket off of the meds.> > |> |> > |> |> > |> |35 male. Diagnosed 04/2011. AVS scheduled 08/23. Tested for GRA -> > |> |Negative.> > |> |> > |> |> > |> |> > |> |------------------------------------> > |> |> > |> |

[Guest guest]

The state this is a randomized study which it is but only observational. What they need and I would hope are working on as the Saudi's have extraordinarly wealth is a trial to show that adding Vit D helps levels get better and the health of the children get better.Observational studies are what we call hypothesis generating. The testing of the Ho is the harder but more important part of the next step.Trust they have such studies ongoing in SAUDI AND THRU NIH.CE Grim MD On Jul 30, 2012, at 9:07 PM, wrote:

Dr. Grim, I did not spend a lot of time validating that article since I recognized one of the authors. You may not be aware of it because it hadn't been foun "in your day"! It appears to be relative new if I remember my conversation with Dr. Moriatis and looking t some of the dates. Here is that author and a summry of a follow on that I found when I went to get his info:

Dr. Chrousos

Bethesda Endocrinology, Diabetes, & Metabolism

¡¡

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Advertisement

Dr. Chrousos, MD, practices Endocrinology, Diabetes, & Metabolism in Bethesda, MD at National Intitutes Of Health. Dr. Chrousos received his medical degree from Univ Athens, Fac Med, Sch Of Hlth Sci, Nat'L & Kapodistrian, Athens.

Specialty: Endocrinology, Diabetes, & Metabolism #View doctors who practice Endocrinology, Diabetes, & Metabolism in BethesdaGender: MaleYears of Experience: 37¡¡¡¡¡¡Journal Article Vitamin D deficiency and calcium intake in reference to increased body mass index in children and adolescents.bySara Al-Musharaf, Abdulaziz Al-Othman, Nasser M Al-Daghri, Soundararajan Krishnaswamy, Deqa S Yusuf, Khalid M Alkharfy, Yousef Al-Saleh, S Al-Attas, Majed S Alokail, Osama Moharram, Sobhy Yakout, Shaun Sabico, P Chrousos College of Science, King Saud University Women's Section, Riyadh, Kingdom of Saudi Arabia.

European Journal of Pediatrics (impact factor: 1.28). 02/2012; DOI:10.1007/s00431-012-1686-8

0 Votes ¡¤

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0 Requests AbstractVitamin D deficiency has been linked to several chronic diseases in adults. Studies focusing on children and adolescents, however, are limited. In this randomized cross-sectional study, we aimed to determine the prevalence of vitamin D deficiency and its relationship with childhood obesity and dietary calcium intake among a population of healthy urban Saudi children and adolescents. To achieve this, 331 randomly selected Saudi children (53.8% females and 46.2% males) aged 6-17 years were included. Demographic, medical, and dietary information were collected; anthropometrics were measured. Levels of serum fasting glucose, lipid profile, 25(OH) D, and for albumin corrected calcium were analyzed. Vitamin D deficiency was noted in all subjects, with girls having significantly lower vitamin D levels than boys. Mean calcium intake was found to be 60% of the required dietary allowance (RDA), while the mean vitamin D intake was 23% of RDA. Vitamin D status and calcium intake were comparable in both normal and overweight/obese children and adolescents. Vitamin D status was highest among children who had calcium intake >800 mg/day. In adolescents there was insignificant but decreasing trend in BMI, which was observed to be highest among those whose calcium intake was <250 mg/day and lowest among those taking >800 mg/day. Conclusion: results from this study suggest the importance of vitamin D fortification and increased dietary calcium in the Saudi diet to meet RDA requirements and avoid onset of vitamin D deficiency-related diseases in Saudi children and adolescents. Source: PubMed.... > > > > |>> > > > |> I found that vit-D interferes with calcium channels of kidneys> > > > |> blocking the effects of some medications like amlodipine...or perhaps> > > > |> to some degree Spiro...If you wait another 3 weeks you will know if bp> > > > |> is shooting up without Spiro or not...but lucky you, 118/78 was when I> > > > was> > > > |20 !> > > > |>> > > > |> Max, 62M> > > > |>> > > > |> | Blood Pressure lower off of Spiro? Why?> > >> > > >>

[Guest guest]

Prof. Nasr, a UCLA researcher is specialist in vit-D but he advises that the best vit-D is sun during noon hours through the skin….etc. Max. The state this is a randomized study which it is but only observational. What they need and I would hope are working on as the Saudi's have extraordinarly wealth is a trial to show that adding Vit D helps levels get better and the health of the children get better. Observational studies are what we call hypothesis generating. The testing of the Ho is the harder but more important part of the next step. Trust they have such studies ongoing in SAUDI AND THRU NIH. CE Grim MD On Jul 30, 2012, at 9:07 PM, wrote:

[Guest guest]

http://www.facebook.com/pages/Farhad-Nasr-Chimeh-MD/192884460787135?sk=info

| Re: Blood Pressure lower off of Spiro? Why?

|

|He (or his sister) isn't by any chance an oncologists are they?

|

|

|>

|

|

|

|

|------------------------------------

|

|

[Guest guest]

Cancer effects of mid-day sun can be easily eliminated with all the medical

knowledge available...but vit-D and all other benefits of mid-day sun can

reach the body. I love to bike during hot summer mid-day sun since childhood

and have no signs of cancer yet!

Max, 62M

| Re: Blood Pressure lower off of Spiro? Why?

|

|Max, I wasn't questioning his qualifications to make such a statement, I

was

|questioning if it was the best way to get the Vit D when you factored in

the risk

|of cancer. Dr. Moriatis specifically included that in his discussion with

me.

|

|

|>

|> http://www.facebook.com/pages/Farhad-Nasr-Chimeh-

|MD/192884460787135?sk

|> =info

|>

|>

[Guest guest]

Trust you wear a helmet as not wearing one is prob greatest risk of biking. ;-)CE Grim MDOn Jul 31, 2012, at 10:22 AM, MedStat wrote:

Cancer effects of mid-day sun can be easily eliminated with all the medical

knowledge available...but vit-D and all other benefits of mid-day sun can

reach the body. I love to bike during hot summer mid-day sun since childhood

and have no signs of cancer yet!

Max, 62M

| Re: Blood Pressure lower off of Spiro? Why?

|

|Max, I wasn't questioning his qualifications to make such a statement, I

was

|questioning if it was the best way to get the Vit D when you factored in

the risk

|of cancer. Dr. Moriatis specifically included that in his discussion with

me.

|

|

|>

|> http://www.facebook.com/pages/Farhad-Nasr-Chimeh-

|MD/192884460787135?sk

|> =info

|>

|>

[Guest guest]

good fact checking. CE Grim MDOn Jul 31, 2012, at 11:14 AM, wrote:

And I hope your luck continues! As you get further north, you are in

Canada right, the effects are less than if let's say the southern

states. If "all this medical knowledge" includes sunscreens that

reduces the absorbption proces!

BTW, I checked you doctor source and I take back my endorsement. He has

nothing on Pubmed. His facebook site is mostly in a foriegn language.

It looks like he has a radio or tv show. Not sure what his credentials

are.

> |>

> |> http://www.facebook.com/pages/Farhad-Nasr-Chimeh-

> |MD/192884460787135?sk

> |> =info

> |>

> |>

>

[Guest guest]

Better you stick with vit-D pills…. no sunshine for you! ||And I hope your luck continues! As you get further north, you are in Canada|right, the effects are less than if let's say the southern states. If " all this|medical knowledge " includes sunscreens that reduces the absorbption proces!||BTW, I checked you doctor source and I take back my endorsement. He has|nothing on Pubmed. His facebook site is mostly in a foriegn language.|It looks like he has a radio or tv show. Not sure what his credentials are.||