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Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

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There is absolutely no doubt in my mind that Karac's autism was caused

by thimerosal. Pat K

Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites



thats what happened to JJ. I have the bad lot numbers to prove it. Lois

No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respected researchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous model systemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects of Thimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System, Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department of Biologyand Environmental Science, University of Cardinal Stefan Wyszynski, Warsaw,Poland funded by grants from the European Commission, the Foundation forPolish Science, and the Ministry of Science and Higher Education of Poland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in HippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, has beenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising in viewof the fact that all mercurials are highly toxic, particularly to developingorganisms. In the past decade concerns emerged about the possibility thatTHIM from vaccines might contribute to certain neurodevelopmental disordersin children...Unfortunately, it is still added to pediatric vaccines in lessdeveloped countries, including Poland, potentially damaging the health ofchildren."These investigators then reported [emphasis added], "THIM is metabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics and toxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effects ofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. We examined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to 10min) exposure to thimerosal at concentrations up to 100 ìM, there was nosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was a significantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents (p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion of neuronsafter 60-90 min exposure; recordings were always conducted in the healthiestlooking neurons."These investigators concluded [emphasis added], "The results reveal complexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABA responses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likely involvebinding to these macromolecules."Sincerely, Geier

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Share on other sites

How is your wrist? Pat K

Re: Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues



thats what happened to JJ. I have the bad lot numbers to prove it. Lois

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites



Hanging in there Pat. It doesan't hurt that much. Mostley hard to deal with not being able to do what I normely do. Lois(:

No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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Share on other sites

How is J doing? Karac had one of his sweet days yesterday. It is

sounding like you are going to get by without the surgery. hugs, Pat K

Re: Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues



Hanging in there Pat. It doesan't hurt that much. Mostley hard to deal

with not being able to do what I normely do. Lois(:

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites



I am worried about how weak my wrist will be when they take the cast off. J was ok today.......yesterday he had some agression and hit me. Jake had to get him. what a mess! Lois

No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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Share on other sites

I agree with you there. The same for my son on.

From: Pat <pkuenstler@...>autism Sent: Fri, January 14, 2011 5:48:51 PMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

There is absolutely no doubt in my mind that Karac's autism was caused by thimerosal. Pat K Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking

Thimerosal (Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respected researchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous model systemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects of Thimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology

of the Nervous System, Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department of Biologyand Environmental Science, University of Cardinal Stefan Wyszynski, Warsaw,Poland funded by grants from the European Commission, the Foundation forPolish Science, and the Ministry of Science and Higher Education of Poland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in HippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, has beenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising in viewof the fact that all mercurials are highly toxic, particularly to

developingorganisms. In the past decade concerns emerged about the possibility thatTHIM from vaccines might contribute to certain neurodevelopmental disordersin children...Unfortunately, it is still added to pediatric vaccines in lessdeveloped countries, including Poland, potentially damaging the health ofchildren."These investigators then reported [emphasis added], "THIM is metabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics and toxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effects ofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. We

examined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to 10min) exposure to thimerosal at concentrations up to 100 ìM, there was nosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was a significantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents (p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion of neuronsafter 60-90 min exposure; recordings were always conducted in the healthiestlooking neurons."These investigators concluded [emphasis added], "The results reveal complexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABA responses.The neurotoxic effects of both

mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likely involvebinding to these macromolecules."Sincerely, Geier

Link to comment
Share on other sites

Lana, I would love to hear more about on. Pat K

Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites

When he was very little, he started making the usual sounds and then he got his vaccines. He is nonverbal and 17 years old. Has classic autism. I strongly believe that vaccines do harm autistic children. How about your child?

lana

From: Pat <pkuenstler@...>autism Sent: Sun, January 16, 2011 7:50:43 AMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

Lana, I would love to hear more about on. Pat K Fw: [MercuryFreeland] FW: No One's PayingAttention...But The Endless Stream of Studies Linking Thimerosal(Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in

yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and

Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the

healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure

for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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We thought Karac was brilliant. He was singing the ABC song and

Twinkle Twinkle Little Star and could read and count the numbers until

20 before he was two years old. After the shot he lost language and

eye contact; he would not respond to his name. I did ABA with him and

he regained some until he started to school. He has made no progress

since and has lost some. He is 18 and I think a tetanus shot that he

had when he was about 8 caused a regression. He is in the 12 grade now

and finally has a teacher who realizes that he can learn. I am hoping

he makes some progress this semester. Pat K

Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites

Good Morning Everyone!

I am usually a silent observer of the group...I take to heart everyone's trials and triumphs and ask God what it all means. This strange thing...this Autism...in all its tragic, miraculous, amazing, hurtful, inspiring forms. What journey is this that some of us have been chosen to take? I ask for Grace to accept the answers to these questions as they unfold.

Our Josiah is 3 and 8 mos. now. His ABA is working beautifully with him and he is due for his year re-evaluation on March 2. I have often wondered about the source of his Autisms and have concluded that he was born so. I do believe that in MANY cases, and perhapse his as well, too many or the wrong vaccines can exacerbate autistic symptoms and behaviors. I do think they may release predispositions that are already genetically there. The singular cause...perhaps not. But a very potential factor in some cases. What are your thoughts?

P.

From: Pat <pkuenstler@...>autism Sent: Mon, January 17, 2011 8:55:18 AMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

We thought Karac was brilliant. He was singing the ABC song and Twinkle Twinkle Little Star and could read and count the numbers until 20 before he was two years old. After the shot he lost language and eye contact; he would not respond to his name. I did ABA with him and he regained some until he started to school. He has made no progress since and has lost some. He is 18 and I think a tetanus shot that he had when he was about 8 caused a regression. He is in the 12 grade now and finally has a teacher who realizes that he can learn. I am hoping he makes some progress this semester. Pat K Fw: [MercuryFreeland] FW: No One's PayingAttention...But The Endless Stream of Studies Linking Thimerosal(Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear

Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal

Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin

children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to

thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier[Non-text

portions of this message have been removed]------------------------------------

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Share on other sites



JJ was the same way. He had great eye contact when he was little. Lois

No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

Link to comment
Share on other sites

Is he in a special needs school? Do you remember me? Lana

From: Pat <pkuenstler@...>autism Sent: Mon, January 17, 2011 7:55:18 AMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

We thought Karac was brilliant. He was singing the ABC song and Twinkle Twinkle Little Star and could read and count the numbers until 20 before he was two years old. After the shot he lost language and eye contact; he would not respond to his name. I did ABA with him and he regained some until he started to school. He has made no progress since and has lost some. He is 18 and I think a tetanus shot that he had when he was about 8 caused a regression. He is in the 12 grade now and finally has a teacher who realizes that he can learn. I am hoping he makes some progress this semester. Pat K Fw: [MercuryFreeland] FW: No One's PayingAttention...But The Endless Stream of Studies Linking Thimerosal(Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear

Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal

Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin

children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to

thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier[Non-text

portions of this message have been removed]------------------------------------

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Share on other sites

I think it would have been easier on us if Karac had appeared autistic

in the beginning. Pat K

Re: Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues



JJ was the same way. He had great eye contact when he was little. Lois

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites

No, Karac is in a special needs class; at one time he was mainstreamed,

but he regressed way too much for that. Tell me more about yourself

and your child to refresh my memory. Pat K

Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites

and others

I am usually silent on this debate had it so many times in my head it hurts. I totally agree with , now that I look back at and his birth. He never wanted to be held unless it was skin to skin and he would scream unmercifully almost all day. We did find that he had Gastro problems couldnt' digest my breast milk, although the screaming did not stop when he was on formula.

He never crawled - well maybe a week and then he was crusing at 6 months of age and walking at 7 - I truly believe he wanted to get away from me and it was not a game he did not want to be touched, lightly or with pressure if anything it would be with deep deep pressure.

I gave him the shots on time until he was diagnosed at 20 mnths with PDD/NOS. He no longer gets most vaccines - had to vaccinate with tetanus for Boy Scouts which my son adores but other than that nothing. He is now a bright brillant boy who is being a teen and no longer wants me around - but he has a side of empathy that I never new an Autie can have.

Yes I believe the vaccines did something, what I don't know, my child never really talked, never grunted, never pointed just wanted to be by himself. We got him in my own form of ABA therapy everyday from someone OT, PT, ST, DT, nothing more than an hour a day - he couldn't take more - make that I couldn't take more of the crying and the screaming.

But he is one of the lucky ones once we got the Verbal Apraxia going the right direction he became over verbal and now uses it as a stim. I wished he would talk and now he does.

So that is just my 2 cents yes vaccines did something to my son what I don't know - but he did have it at birth you can just go back over his life until the 20 months until he was diagnosed and see all the markers.

Autism sucks and it will continue to suck until we find a cure or something. Would I take it away from my son - not at this point, because it is who he is. It is not a cancer that is killing him so I don't fight it anymore I just work with it and make him work as hard as he can in school and in therapy and we just live day by day.

Love to all of you who are struggling.

Sharon - mom to - PDD/NOS, Aspergers, Hyperlexia, Global Apraxia, Hypotonia and all around good kidI did not chose to have Autism in my life, God did

From: <npcox649@...>Subject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continuesautism Date: Monday, January 17, 2011, 9:16 AM

Good Morning Everyone!

I am usually a silent observer of the group...I take to heart everyone's trials and triumphs and ask God what it all means. This strange thing...this Autism...in all its tragic, miraculous, amazing, hurtful, inspiring forms. What journey is this that some of us have been chosen to take? I ask for Grace to accept the answers to these questions as they unfold.

Our Josiah is 3 and 8 mos. now. His ABA is working beautifully with him and he is due for his year re-evaluation on March 2. I have often wondered about the source of his Autisms and have concluded that he was born so. I do believe that in MANY cases, and perhapse his as well, too many or the wrong vaccines can exacerbate autistic symptoms and behaviors. I do think they may release predispositions that are already genetically there. The singular cause...perhaps not. But a very potential factor in some cases. What are your thoughts?

P.

From: Pat <pkuenstler@...>autism Sent: Mon, January 17, 2011 8:55:18 AMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

We thought Karac was brilliant. He was singing the ABC song and Twinkle Twinkle Little Star and could read and count the numbers until 20 before he was two years old. After the shot he lost language and eye contact; he would not respond to his name. I did ABA with him and he regained some until he started to school. He has made no progress since and has lost some. He is 18 and I think a tetanus shot that he had when he was about 8 caused a regression. He is in the 12 grade now and finally has a teacher who realizes that he can learn. I am hoping he makes some progress this semester. Pat K Fw: [MercuryFreeland] FW: No One's PayingAttention...But The Endless Stream of Studies Linking Thimerosal(Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study,

"Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new

study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the

existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure;

recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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Two boys: on and Robbie. on nonverbal and is now 17. Robbie 18.

Lana

From: Pat <pkuenstler@...>autism Sent: Mon, January 17, 2011 12:33:52 PMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

No, Karac is in a special needs class; at one time he was mainstreamed, but he regressed way too much for that. Tell me more about yourself and your child to refresh my memory. Pat K Fw: [MercuryFreeland] FW: No One's PayingAttention...But The Endless Stream of Studies Linking Thimerosal(Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study,

"Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new

study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the

existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure;

recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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to show you the difference.....JJ loved to be touched!!!!!! He played good with his toys and at his 18 month check-up he was given his shots and over the next 6 months you could see the change in him and then i got the "hot shot list" which showed the bad lot numbers J had. Now at 23 life is hard for him.

Sheron- be glad that your son can understand boy scouts and can do well in school. J cannot funtion that high. he has to go to a day program while I work. I love JJ BUT hate autism!!!!!!! Lois

No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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Lana, is it helpful having the two boys so close in age? Pat K

Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites

It was nice when they were growing up. Robbie is presently in a foster home. We bring him home every two weeks. The boys do not really play with each other much but I am glad that they are close in age.

From: Pat <pkuenstler@...>autism Sent: Mon, January 17, 2011 9:30:33 PMSubject: Re: Fw: [MercuryFreeland] FW: No One's Paying Attention...But The Endless Stream of Studies Linking Thimerosal (Mercury) with Autism Continues

Lana, is it helpful having the two boys so close in age? Pat K Fw: [MercuryFreeland] FW: No One's

PayingAttention...But The Endless Stream of Studies Linking Thimerosal(Mercury) with Autism Continues No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs

Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are

highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter

systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects

of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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Share on other sites

Karac has a sister that is 4 years older than he is. She loves him and

is good to him, but I thought it would have been nice if he had an

older brother. I have a young male special needs teacher who comes on

the weekends and acts as teacher and friend. They ride bikes, shoot

baskets and eat out together.

Does on go to school? Are you able to work? Pat K

Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
Share on other sites

Oh, Lois, I am so sorry. I'll pray harder. hugs, Pat K

Re: Fw: [MercuryFreeland] FW: No One's Paying

Attention...But The Endless Stream of Studies Linking Thimerosal

(Mercury) with Autism Continues



I am worried about how weak my wrist will be when they take the cast

off. J was ok today.......yesterday he had some agression and hit me.

Jake had to get him. what a mess! Lois

No One's Paying Attention...But The Endless Stream of Studies

Linking Thimerosal (Mercury) with Autism Continues

Dear Everyone,

In yet another study by more well-established and well-respected

researchers

directly links Thimerosal (mercury) exposure with autism in yet another

model system. This new study continues to build upon previous model

systems

linking Thimerosal (mercury) with brain pathology found in subjects

diagnosed with an autism spectrum disorder.

The new study, " Intermingled Modulatory and Neurotoxic Effects of

Thimerosal

and Meruric Ions on Electrophysiological Responses to GABA and NMDA in

Hippocampal Neurons " was published in the peer-reviewed Journal of

Physiology and Pharmacology by investigators from the Wroclaw Medical

University, Wroclaw, Poland, the Marie Curie Chairs Programme at the

Department of Pharmacology and Physiology of the Nervous System,

Institute

of Psychiatry and Neurology, Warsaw, Poland, and the Department of

Biology

and Environmental Science, University of Cardinal Stefan Wyszynski,

Warsaw,

Poland funded by grants from the European Commission, the Foundation

for

Polish Science, and the Ministry of Science and Higher Education of

Poland.

Please, find a copy of the study attached to this email saved as

Modulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA in

Hippocampal

Neurons1.pdf in Adobe Acrobat Format.

This new study described [emphasis added], " Thimerosal (THIM), an

organomercurial containing approximately 49% of mercury by weight, has

been

added for decades to medicinal products, including pediatric vaccines,

without being sufficiently tested for its safety. This is surprising in

view

of the fact that all mercurials are highly toxic, particularly to

developing

organisms. In the past decade concerns emerged about the possibility

that

THIM from vaccines might contribute to certain neurodevelopmental

disorders

in children...Unfortunately, it is still added to pediatric vaccines in

less

developed countries, including Poland, potentially damaging the health

of

children. "

These investigators then reported [emphasis added], " THIM is

metabolized in

the body to ethyl mercury (EtHg) and subsequently to inorganic mercury

forms, which accumulate in tissues of vital organs, including the

brain...the existing data indicate that in pharmacodynamics and

toxicity

THIM/EtHg does not differ significantly from methyl mercury (MeHg)... "

These investigators stated [emphasis added], " Many neurotoxic effects

of

thimerosal have been described, but its interaction with principal

excitatory and inhibitory neurotransmiter systems is not known. We

examined,

using electrophysiological recordings, thimerosal effects on GABA and

NMDA-evoked currents in cultured hippocampal neurons. After brief (3 to

10

min) exposure to thimerosal at concentrations up to 100 ìM, there was

no

significant effect on GABA or NMDA-evoked currents. However, following

exposure for 60-90 min to 1 or 10 ìM thimerosal, there was a

significant

decrease in NMDA-induced currents (p<0.05) and GABAergic currents

(p<0.05).

Thimerosal was also neurotoxic, damaging a significant proportion of

neurons

after 60-90 min exposure; recordings were always conducted in the

healthiest

looking neurons. "

These investigators concluded [emphasis added], " The results reveal

complex

interactions of thimerosal and mercuric ions with the GABAA and NMDA

receptors...thimerosal works slowly, reducing both NMDA and GABA

responses.

The neurotoxic effects of both mercurials are interwoven with their

modulatory actions on GABAA and NMDA receptors, which most likely

involve

binding to these macromolecules. "

Sincerely,

Geier

Link to comment
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thanks Pat! (((hugs))) Lois

No One's Paying Attention...But The Endless Stream of StudiesLinking Thimerosal (Mercury) with Autism ContinuesDear Everyone,In yet another study by more well-established and well-respectedresearchersdirectly links Thimerosal (mercury) exposure with autism in yet anothermodel system. This new study continues to build upon previous modelsystemslinking Thimerosal (mercury) with brain pathology found in subjectsdiagnosed with an autism spectrum disorder.The new study, "Intermingled Modulatory and Neurotoxic Effects ofThimerosaland Meruric Ions on Electrophysiological Responses to GABA and NMDA inHippocampal Neurons" was published in the peer-reviewed Journal ofPhysiology and Pharmacology by investigators from the Wroclaw MedicalUniversity, Wroclaw, Poland, the Marie Curie Chairs Programme at theDepartment of Pharmacology and Physiology of the Nervous System,Instituteof Psychiatry and Neurology, Warsaw, Poland, and the Department ofBiologyand Environmental Science, University of Cardinal Stefan Wyszynski,Warsaw,Poland funded by grants from the European Commission, the FoundationforPolish Science, and the Ministry of Science and Higher Education ofPoland.Please, find a copy of the study attached to this email saved asModulatory-Neurotoxic Effects of Thimerosal on GABA & NMDA inHippocampalNeurons1.pdf in Adobe Acrobat Format.This new study described [emphasis added], "Thimerosal (THIM), anorganomercurial containing approximately 49% of mercury by weight, hasbeenadded for decades to medicinal products, including pediatric vaccines,without being sufficiently tested for its safety. This is surprising inviewof the fact that all mercurials are highly toxic, particularly todevelopingorganisms. In the past decade concerns emerged about the possibilitythatTHIM from vaccines might contribute to certain neurodevelopmentaldisordersin children...Unfortunately, it is still added to pediatric vaccines inlessdeveloped countries, including Poland, potentially damaging the healthofchildren."These investigators then reported [emphasis added], "THIM ismetabolized inthe body to ethyl mercury (EtHg) and subsequently to inorganic mercuryforms, which accumulate in tissues of vital organs, including thebrain...the existing data indicate that in pharmacodynamics andtoxicityTHIM/EtHg does not differ significantly from methyl mercury (MeHg)..."These investigators stated [emphasis added], "Many neurotoxic effectsofthimerosal have been described, but its interaction with principalexcitatory and inhibitory neurotransmiter systems is not known. Weexamined,using electrophysiological recordings, thimerosal effects on GABA andNMDA-evoked currents in cultured hippocampal neurons. After brief (3 to10min) exposure to thimerosal at concentrations up to 100 ìM, there wasnosignificant effect on GABA or NMDA-evoked currents. However, followingexposure for 60-90 min to 1 or 10 ìM thimerosal, there was asignificantdecrease in NMDA-induced currents (p<0.05) and GABAergic currents(p<0.05).Thimerosal was also neurotoxic, damaging a significant proportion ofneuronsafter 60-90 min exposure; recordings were always conducted in thehealthiestlooking neurons."These investigators concluded [emphasis added], "The results revealcomplexinteractions of thimerosal and mercuric ions with the GABAA and NMDAreceptors...thimerosal works slowly, reducing both NMDA and GABAresponses.The neurotoxic effects of both mercurials are interwoven with theirmodulatory actions on GABAA and NMDA receptors, which most likelyinvolvebinding to these macromolecules."Sincerely, Geier

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