Guest guest Posted October 18, 2000 Report Share Posted October 18, 2000 no, your body needs N-acetylcysteine, L glutamine and glycine to make glutathione according to an old post I had from Andy. He said that giving glutathione by itself is not absorbed well, it's digested in the gut. I am confused why it it listed in the new protocol to be given that way that it is, doesn't make much sense, Val Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2000 Report Share Posted October 18, 2000 The only thing is know about cysteine is that sometimes it builds up and supplimenting it makes things worse. It is an excitory amimo. Why it builds up in certain cases I don't know . someone else may know and could tell both of us. kelly << no, your body needs N-acetylcysteine, L glutamine and glycine to make glutathione according to an old post I had from Andy. He said that giving glutathione by itself is not absorbed well, it's digested in the gut. I am confused why it it listed in the new protocol to be given that way that it is, doesn't make much sense, Val >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2000 Report Share Posted October 18, 2000 In a message dated 10/17/2000 11:47:33 PM Eastern Daylight Time, happymomto4@... writes: << Does anyone know--is glutathione the same thing as L-glutamine? Thanks. M >> No wendy it is different. gluthathione is a peptide that rids the body of unwanted stuff . so technical I can't stand it. L-glutamime is an amino acid that is a component of gluthatione as is glycine and cysteine. kelly Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2000 Report Share Posted October 18, 2000 In a message dated 10/18/00 7:51:19 AM Central Daylight Time, scromb@... writes: << no, your body needs N-acetylcysteine, L glutamine and glycine to make glutathione according to an old post I had from Andy. He said that giving glutathione by itself is not absorbed well, it's digested in the gut. I am confused why it it listed in the new protocol to be given that way that it is, doesn't make much sense, Val >> They're probably talking about Reduced L-Glutathione which is a mixture of the ingredients you listed above that are used by the body to make l-glutathione. Gaylen Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2000 Report Share Posted October 18, 2000 In a message dated 10/18/2000 10:43:33 AM Eastern Daylight Time, Nomoremetals@... writes: << hey're probably talking about Reduced L-Glutathione which is a mixture of the ingredients you listed above that are used by the body to make l-glutathione. Gaylen >> t hat what was asked How to make L-gluthatione. glycine, cysteine and glutamine makes gluthathione. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2008 Report Share Posted October 17, 2008 HI, I'm not familiar with Nutrical (when I Googled it, it came up as an animal product) But as far as glutathione, my naturopath recommended I take 600mg pills 3X daily of NAC, N-acetylCysteine, instead. She said that the human body uses the NAC to make its own glutathione, whereas if you buy glutathione itself, it is prone to easy oxidation, which negates its affect as an anti-oxidant. (I do know someone who was sicke nough, however, to get glutathione IV for two weeks straight, but it was obviously under a doctor's care. The reason I take it is that I have MCS, and that the glutathione levels in the liver of someone with MCS are low, and can't help get toxins out of there well enough. I would love to hear others' comments on this. Deb On Fri, Oct 17, 2008 at 1:39 AM, healthyhayashis <amhayashi@...>wrote: > Have any of you heard of Nutrical? I may be WAY behind, I just found > it online and was wondering what you thought of it? Does it work? > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2008 Report Share Posted October 17, 2008 Gosh, I am such a spaz!! I don't know where the heck the name nutrical came from!!!! The product I meant to inquire about is called immunocal!!!!! Sorry for the mix up!!! Adrean > > HI, > > I'm not familiar with Nutrical (when I Googled it, it came up as an animal > product) > > But as far as glutathione, my naturopath recommended I take 600mg pills 3X > daily of NAC, N-acetylCysteine, instead. She said that the human body uses > the NAC to make its own glutathione, whereas if you buy glutathione itself, > it is prone to easy oxidation, which negates its affect as an anti- oxidant. > (I do know someone who was sicke nough, however, to get glutathione IV for > two weeks straight, but it was obviously under a doctor's care. > > The reason I take it is that I have MCS, and that the glutathione levels in > the liver of someone with MCS are low, and can't help get toxins out of > there well enough. > > I would love to hear others' comments on this. > > Deb > > > On Fri, Oct 17, 2008 at 1:39 AM, healthyhayashis <amhayashi@...>wrote: > > > Have any of you heard of Nutrical? I may be WAY behind, I just found > > it online and was wondering what you thought of it? Does it work? > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2008 Report Share Posted October 17, 2008 Deb, You might want to check this paper out. I am sure that NAC is very useful to people recovering from sick buildings.. It has been for me.. A few months ago I saw ths paper which describes a very interesting aspect of NAC in toxicology.. Its very technical but you might want to check it out.. Chemically Diverse Toxicants Converge on Fyn and c-Cbl to Disrupt Precursor Cell Function http://biology.plosjournals.org/perlserv/?request=get-document & doi=10.1371/journ\ al.pbio.0050035 Zaibo Li, Tiefei Dong, Pröschel, Mark Noble*<http://biology.plosjournals.org/perlserv/?request=get-document & doi=10.137\ 1/journal.pbio.0050035#cor1> *1* Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, United States of America Identification of common mechanistic principles that shed light on the action of the many chemically diverse toxicants to which we are exposed is of central importance in understanding how toxicants disrupt normal cellular function and in developing more effective means of protecting against such effects. Of particular importance is identifying mechanisms operative at environmentally relevant toxicant exposure levels. Chemically diverse toxicants exhibit striking convergence, at environmentally relevant exposure levels, on pathway-specific disruption of receptor tyrosine kinase (RTK) signaling required for cell division in central nervous system (CNS) progenitor cells. Relatively small toxicant-induced increases in oxidative status are associated with Fyn kinase activation, leading to secondary activation of the c-Cbl ubiquitin ligase. Fyn/c-Cbl pathway activation by these pro-oxidative changes causes specific reductions, in vitro and in vivo, in levels of the c-Cbl target platelet-derived growth factor receptor-α and other c-Cbl targets, but not of the TrkC RTK (which is not a c-Cbl target). Sequential Fyn and c-Cbl activation, with consequent pathway-specific suppression of RTK signaling, is induced by levels of methylmercury and lead that affect large segments of the population, as well as by paraquat, an organic herbicide. Our results identify a novel regulatory pathway of oxidant-mediated Fyn/c-Cbl activation as a shared mechanism of action of chemically diverse toxicants at environmentally relevant levels, and as a means by which increased oxidative status may disrupt mitogenic signaling. These results provide one of a small number of general mechanistic principles in toxicology, and the only such principle integrating toxicology, precursor cell biology, redox biology, and signaling pathway analysis in a predictive framework of broad potential relevance to the understanding of pro-oxidant–mediated disruption of normal development. Quote Link to comment Share on other sites More sharing options...
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