Guest guest Posted October 1, 2000 Report Share Posted October 1, 2000 THIS SHOWS THERE IS MORE THAN ONE WAY TO SKIN A CAT. WHAT I DID WAS USE Chemet DMSA Succimer ON A CONSTANT BASIS. I CHANGED THE PROTOCOLS COMPLETLY, I THINK IT HAS WORKED WONDERFULLY. ps WHAT is stimming??????????????????? > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > Autism and Mercury Detoxification > P. Kane, Ph.D. and J. Mercola, D.O. > > Recently, it has been proposed that autism may be the aftermath of > exposure > to mercury such as ethyl mercury used as a preservative, thimerosal, > in > pediatric vaccinations. The article in this newsletter issue reviews > > this > evidence. > > Currently Recommend Pediatric Mercury Protocol > > The protocol is always being improved. Drs. Klinghardt, Kane and > Mercola > revised this in September 2000 and the most current recommendation > can > be > found by clicking here. Small changes are likely to be regularly > posted > but > we will likely revise the protocol in December when we all are > presenters at > the Healing Your Brain 2000 Seminar. > > We currently are planning hold a one day workshop at the American > Academy of > Environmental Medicine to invite some of the top clinicians in > mercury > detoxification to further improve the program. Additionally, Wayne > Obie, of > TalkInternational.com is planning on facilitating an international > collaboration on a revised mercury detoxification program. > > What is DMSA and Why Don't We Recommend It? > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > which > each > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > forming > water soluble chelates which increases the urinary excretion of > lead. > > There are a number of physicians who have started to use DMSA to > remove > the > mercury from children with autism. The dose used for mercury > detoxification > is much lower than that for lead and many children seem to have > received > benefit from this approach. > > A time released DMSA is being used for 7 days on, 7 days off or 3 > days > on, 4 > days off for an extended period of time (up to 6 months). > > However, some natural medicine clinicians have some serious concerns > > about > the use of DMSA. There have been cases of: > > > seizures > > increased self-stimming > > and compromised central nervous system function in some children. > > > DMSA and Mercury Redistribution To The Brain > > It appears that DMSA and lipoic acid can create tissue > redistribution > of > mercury as decreasing Hg levels in the kidney (the organ > accumulating > Hg most > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > heart, > muscle and liver (Gregus et al). > > Natural medical physicians throughout the US have reported MS > symptoms > in > adults and intractable seizures in pediatric patients with high dose > > and > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > Succimer. > > Other Problems With DMSA > > Extended use of DMSA can cause mild to moderate neutropenia with > increased > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > Blood > Urea > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > convulsions, > rash, > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > neuropathy, > decreased urination, arrhythmia, infection. Zinc excretion doubles > during the > administration of DMSA. Patients must be kept hydrated as renal > function can > be compromised. > > For the above described reasons in all good conscious we can not > recommend > the use of DMSA for the treatment of mercury toxic pediatric > patients. > > Approaching the fragile brain architecture of young children with > autism, PDD > and seizure disorders brings about tremendous responsibility in > protecting > the children from invasive interventions that risk alteration in > brain > function. > > Hair Analysis For Diagnosis and Treatment > > First, a determination must be made if, in fact, there is a heavy > metal > burden and if so specifically which heavy metals are involved such > as > aluminum, mercury, lead or others. > > This is the reason why hair analysis is a recommended initial > screen. > At this > time we only advise two labs for this determination. Trace Elements > in > Austin, Texas and Analytical Research in Arizona. > > Both of these labs do not wash the hair samples prior to analysis. > This > is a > key factor to proper interpretation of the other nontoxic minerals. > > Other labs would likely give proper heavy metal results, but the > interpretation of the other minerals is key to an effective > supplementation > program. Chelation removes other minerals aside from mercury and > these > must > be replaced properly if one wished to avoid complications. > > Establishing Metabolic Stability Prior To Detoxification > > One must be relatively healthy to sustain the process of > detoxification. Once > metabolic stability is established physicians often find that gentle > > biological interventions clear heavy metal burdens without the need > for > medication that holds the potential risk of negative side effects or > > merely > redistribution of heavy metals. > > Clearing heavy metals may be approached by first reestablishing the > mineral > base, supporting biliary function/ digestion, insuring the patient > is > properly hydrated (children with autism are frequently dehydrated), > and > most > importantly supporting hepatic function and metabolism > > Adults with heavy metal toxicity generally have significant > suppression > of > omega 6 arachidonic acid and a significant elevation of very long > chain > fatty > acids (Kane) as the cellular impact of heavy metals burdens block > receptor > sites such as G proteins and ultimately suppress the beta oxidation > of > lipids > and cellular respiration. > > Children with autism consistently present with an elevation of > VLCFAs > However, red cell lipid levels of arachidonic are variable, elevated > in > some > patients while deeply suppressed in others. > > Dietary Fat Intervention Must Be Considered > > Administration of fish oils suppresses omega 6 and structural lipids > > and this > will suppress the production of arachidonic acid. To balance fat > metabolism > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > before > introducing omega 3 lipids. > > Patient outcomes may be compromised if one uses fish oils prior to > omega 6 > fatty acids. The omega 6 fatty acid of choice would be evening > primrose > oil. > Additionally, supporting the digestion of fats with bile salts and > lipase is > frequently required to maximize fat absorption and digestion. > > Japan and Mercury Exposure Example > > The impact of Hg upon human health was brought to light in the > mid-50s > with > the Minamata disaster in Japan. As noted in the documentary 'Message > to > Minamata to the World' the impact of Hg is devastating, most > prominently to > the CNS. Interestingly, autistic behavior can observed in the > documentary of > Minamata children in original footage after the disaster. > > In 1993 Kane found an interesting correlation in the literature > between > autism and Hg with the occurrence of autism presenting in adulthood > occurring > in Japan. The presentation of autism in these individuals was linked > to > ornithine transcarbamylase deficiency, the most common urea cycle > defect. > Damage to this enzyme can occur with exposure to mercury. > > Low levels of ornithine transcarbamylase (OTC) leads to states of > hyperammonemia, seizures and stroke. The enzyme OTC controls > ammonia, > critical issues in states of epilepsy and autism. The often spacy, > confused > behavior 'brain fog' that is frequently observed in these disorders > may > be > attributed states of hyperammonemia as ammonia reaches the brain. > > Suggested treatment of mildly suppressed levels of OTC includes > sodium > benzoate and phenylacetate. However, Kane and other clinicians have > observed > positive clinical usefulness of Ca/Mg butyrate, digestive > intervention > targeted to biliary flow, appropriate buffers, and stabilization of > electrolytes and the trace mineral base. > --- End forwarded message --- > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 1, 2000 Report Share Posted October 1, 2000 Quit being a * & $# !!! This is a list to help people. Andy has been doing this quite well. At least he doesnot tell us to give outrageous doses to our children because it worked for adults. I know you say you are knew to the computer so a bit of advice: please don't use all caps. This is computer for yelling. We try to keep things under control. Haven't you noticed that you are the only one doing this? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 1, 2000 Report Share Posted October 1, 2000 Most of us in this group are not too fond of the Federal Government, and this is putting it litely. They got us into this mess and are not doing too much to get our kids out of it. I am an adult who will be getting amalgams removed and chelating. At least I dont require an IEP for myself or speech therapy or OT or ABA. And on top of that be told that the programs are short funded. No, that has been reserved for my 2 yearold. So, yes adults are affected but in a totally different way. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Hopefully the spamming and slandering will come to an end soon. I have contacted the originators of this board and it is being investigated as disruptive. Then maybe we can go back to helping each other. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Okay, . Got it figured out. I wasn't making the connection. I think you are 100% right on. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 I was also shot down when I attempted to obtain info on FGF. There becomes a time when I line is crossed with certain individuals who make personal attacks and continue to shove info down our throats. That is why I am investigating this as being counter-productive to the group. I love hearing different opinions but do not wish to be attacked for making them. All kids are different, thats what we have to remember. My fear is that some desperate individual will use some unfounded advice on their child and end up with disasterous results. I like opinions and personal accounts. Medical Advice? That is what I pay my DAN Dr. for: who also is not a big fan of our government and FDA. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 If you are having difficulties in your insurance covering tests or treatments, may I make a suggestion. Find a DAN Dr. who is affiliated with a large clinic/hospital. Dr. Jane El-Dahr in New orleans is. And I must admit that because of the clinic setting, you will not get much time on a visit, but they can code everything so insurance pays. Also, they usually work closely with other specialists within the clinic and have a good chance of getting Secretin and other treatments for you. Call around and see if one accepts your insurance. It may not be personal attention but you will get a lot done for your small co-pay. WendiD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 ps WHAT isstimming??????????????????? , Stimming is slang for self-stimulation. It is one of THE primary symptoms of autism. Most people "stim" to some degree or another, (for example, chewing on the end of a pencil, constantly stroking a beard, running your hands through your hair) but in children with autism, sometimes the "stimming" can actually interfere with everything else they are supposed to be doing, such as learning. Examples of "stims" that my son has are tapping incessantly on everything, jumping up and down in front of the TV, chewing on all the woodwork in our house, shrieking loudly for no apparent reason, spitting, slurping, tapping on his fingernail or on other people ... the list goes on and on. It is an abnormal behavior that interferes with "normal" behavior. We use ABA (Applied Behavior Analysis) techniques to keep the stims under control. However, when he is on DMSA, it is very difficult to keep him calm and directed. The moment I turn my head away, he is at it again. (During the "off" weeks this is not the case.) This is ONE of the reasons that is is not a good idea for children with autism stay in a permanent "ON" cycle. We use the "OFF" weeks to make up for some of the control that is lost in the "ON" weeks. (Cary, NC)persistentC@... > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm> > > > Autism and Mercury Detoxification > P. Kane, Ph.D. and J. Mercola, D.O. > > Recently, it has been proposed that autism may be the aftermath of > exposure > to mercury such as ethyl mercury used as a preservative, thimerosal,> in > pediatric vaccinations. The article in this newsletter issue reviews > > this > evidence. > > Currently Recommend Pediatric Mercury Protocol> > The protocol is always being improved. Drs. Klinghardt, Kane and > Mercola > revised this in September 2000 and the most current recommendation> can > be > found by clicking here. Small changes are likely to be regularly> posted > but > we will likely revise the protocol in December when we all are > presenters at > the Healing Your Brain 2000 Seminar. > > We currently are planning hold a one day workshop at the American > Academy of > Environmental Medicine to invite some of the top clinicians in> mercury > detoxification to further improve the program. Additionally, Wayne > Obie, of > TalkInternational.com is planning on facilitating an international > collaboration on a revised mercury detoxification program.> > What is DMSA and Why Don't We Recommend It?> > DMSA is a FDA currently approved drug. It is a mixed disulfide in> which > each > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > forming > water soluble chelates which increases the urinary excretion of > lead.> > There are a number of physicians who have started to use DMSA to> remove > the > mercury from children with autism. The dose used for mercury > detoxification > is much lower than that for lead and many children seem to have > received > benefit from this approach.> > A time released DMSA is being used for 7 days on, 7 days off or 3> days > on, 4 > days off for an extended period of time (up to 6 months).> > However, some natural medicine clinicians have some serious concerns > > about > the use of DMSA. There have been cases of:> > > seizures > > increased self-stimming > > and compromised central nervous system function in some children. > > > DMSA and Mercury Redistribution To The Brain> > It appears that DMSA and lipoic acid can create tissue > redistribution > of > mercury as decreasing Hg levels in the kidney (the organ > accumulating > Hg most > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > heart, > muscle and liver (Gregus et al). > > Natural medical physicians throughout the US have reported MS> symptoms > in > adults and intractable seizures in pediatric patients with high dose > > and > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > Succimer. > > Other Problems With DMSA> > Extended use of DMSA can cause mild to moderate neutropenia with > increased > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and> Blood > Urea > Nitrogen (BUN). Adverse reactions to DMSA include ataxia,> convulsions, > rash, > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > neuropathy, > decreased urination, arrhythmia, infection. Zinc excretion doubles > during the > administration of DMSA. Patients must be kept hydrated as renal > function can > be compromised. > > For the above described reasons in all good conscious we can not > recommend > the use of DMSA for the treatment of mercury toxic pediatric > patients.> > Approaching the fragile brain architecture of young children with > autism, PDD > and seizure disorders brings about tremendous responsibility in > protecting > the children from invasive interventions that risk alteration in> brain > function. > > Hair Analysis For Diagnosis and Treatment> > First, a determination must be made if, in fact, there is a heavy> metal > burden and if so specifically which heavy metals are involved such > as > aluminum, mercury, lead or others.> > This is the reason why hair analysis is a recommended initial > screen. > At this > time we only advise two labs for this determination. Trace Elements> in > Austin, Texas and Analytical Research in Arizona. > > Both of these labs do not wash the hair samples prior to analysis.> This > is a > key factor to proper interpretation of the other nontoxic minerals.> > Other labs would likely give proper heavy metal results, but the > interpretation of the other minerals is key to an effective > supplementation > program. Chelation removes other minerals aside from mercury and> these > must > be replaced properly if one wished to avoid complications.> > Establishing Metabolic Stability Prior To Detoxification> > One must be relatively healthy to sustain the process of > detoxification. Once > metabolic stability is established physicians often find that gentle > > biological interventions clear heavy metal burdens without the need> for > medication that holds the potential risk of negative side effects or > > merely > redistribution of heavy metals. > > Clearing heavy metals may be approached by first reestablishing the > mineral > base, supporting biliary function/ digestion, insuring the patient > is > properly hydrated (children with autism are frequently dehydrated),> and > most > importantly supporting hepatic function and metabolism> > Adults with heavy metal toxicity generally have significant> suppression > of > omega 6 arachidonic acid and a significant elevation of very long> chain > fatty > acids (Kane) as the cellular impact of heavy metals burdens block > receptor > sites such as G proteins and ultimately suppress the beta oxidation> of > lipids > and cellular respiration. > > Children with autism consistently present with an elevation of > VLCFAs > However, red cell lipid levels of arachidonic are variable, elevated> in > some > patients while deeply suppressed in others. > > Dietary Fat Intervention Must Be Considered> > Administration of fish oils suppresses omega 6 and structural lipids > > and this > will suppress the production of arachidonic acid. To balance fat > metabolism > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > before > introducing omega 3 lipids. > > Patient outcomes may be compromised if one uses fish oils prior to > omega 6 > fatty acids. The omega 6 fatty acid of choice would be evening> primrose > oil. > Additionally, supporting the digestion of fats with bile salts and > lipase is > frequently required to maximize fat absorption and digestion.> > Japan and Mercury Exposure Example> > The impact of Hg upon human health was brought to light in the> mid-50s > with > the Minamata disaster in Japan. As noted in the documentary 'Message> to > Minamata to the World' the impact of Hg is devastating, most > prominently to > the CNS. Interestingly, autistic behavior can observed in the > documentary of > Minamata children in original footage after the disaster. > > In 1993 Kane found an interesting correlation in the literature> between > autism and Hg with the occurrence of autism presenting in adulthood > occurring > in Japan. The presentation of autism in these individuals was linked> to > ornithine transcarbamylase deficiency, the most common urea cycle > defect. > Damage to this enzyme can occur with exposure to mercury. > > Low levels of ornithine transcarbamylase (OTC) leads to states of > hyperammonemia, seizures and stroke. The enzyme OTC controls > ammonia, > critical issues in states of epilepsy and autism. The often spacy, > confused > behavior 'brain fog' that is frequently observed in these disorders> may > be > attributed states of hyperammonemia as ammonia reaches the brain. > > Suggested treatment of mildly suppressed levels of OTC includes> sodium > benzoate and phenylacetate. However, Kane and other clinicians have > observed > positive clinical usefulness of Ca/Mg butyrate, digestive> intervention > targeted to biliary flow, appropriate buffers, and stabilization of > electrolytes and the trace mineral base.> --- End forwarded message ---> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Dear , We see the same things while on chelation. He also used to be extrmely moody and tantrum easily. This seems to be better. We are now using DMSA/ALA every 4 hours on Friday, Saturday, and Sunday. It definitely affects his therapy on Friday and Monday. Tuesday through Thursday he doing fantastic. I am hoping that over time he becomes less reactive to the chelation so we can have a good week Monday through Friday. Ken Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Oh no, not this again!! Folks, DMPS has not been approved for use in children! And Andy has posted quite a lot about the dangers of DMPS. Hey, even our pediatrician feels VERY comfortable about us using DMSA under our chelating doctor's direction, and the ped. is a VERY CONSERVATIVE man. Some of the statements made below have been taken out of context, and some are just NOT TRUE. The post below makes DMSA chelation sound very dangerous. In fact, DMSA is VERY SAFE. When I asked the doctor who is treating Kenny about this " seizure risk " this doctor said that there is absolutely no evidence of this. In point of fact, the risks of using DMPS are MUCH HIGHER. The post below states: " Natural medical physicians throughout the US have reported MS symptoms in adults and intractable seizures in pediatric patients with high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or Succimer. " However, the chelation protocol being used by reputable doctors is NOT a high dose of DMSA. Even aspirin can be dangerous if taken in high doses for a long period of time. Which all points up the fact that BEFORE you do anything with your child, make sure you have thoroughly RESEARCHED the approach your doctor suggests you take with your child. Ask lots of questions, and make sure your doctor KNOWS what s/he is doing! (Cary, NC) persistentC@... [ ] DMSA/LA:Another View Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm Autism and Mercury Detoxification P. Kane, Ph.D. and J. Mercola, D.O. Recently, it has been proposed that autism may be the aftermath of exposure to mercury such as ethyl mercury used as a preservative, thimerosal, in pediatric vaccinations. The article in this newsletter issue reviews this evidence. Currently Recommend Pediatric Mercury Protocol The protocol is always being improved. Drs. Klinghardt, Kane and Mercola revised this in September 2000 and the most current recommendation can be found by clicking here. Small changes are likely to be regularly posted but we will likely revise the protocol in December when we all are presenters at the Healing Your Brain 2000 Seminar. We currently are planning hold a one day workshop at the American Academy of Environmental Medicine to invite some of the top clinicians in mercury detoxification to further improve the program. Additionally, Wayne Obie, of TalkInternational.com is planning on facilitating an international collaboration on a revised mercury detoxification program. What is DMSA and Why Don't We Recommend It? DMSA is a FDA currently approved drug. It is a mixed disulfide in which each of the sulfur atoms is in disulfide linkage with a cysteine molecule forming water soluble chelates which increases the urinary excretion of lead. There are a number of physicians who have started to use DMSA to remove the mercury from children with autism. The dose used for mercury detoxification is much lower than that for lead and many children seem to have received benefit from this approach. A time released DMSA is being used for 7 days on, 7 days off or 3 days on, 4 days off for an extended period of time (up to 6 months). However, some natural medicine clinicians have some serious concerns about the use of DMSA. There have been cases of: seizures increased self-stimming and compromised central nervous system function in some children. DMSA and Mercury Redistribution To The Brain It appears that DMSA and lipoic acid can create tissue redistribution of mercury as decreasing Hg levels in the kidney (the organ accumulating Hg most abundantly) increases Hg concentrations of Hg in blood, brain, lung, heart, muscle and liver (Gregus et al). Natural medical physicians throughout the US have reported MS symptoms in adults and intractable seizures in pediatric patients with high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or Succimer. Other Problems With DMSA Extended use of DMSA can cause mild to moderate neutropenia with increased SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and Blood Urea Nitrogen (BUN). Adverse reactions to DMSA include ataxia, convulsions, rash, nausea, diarrhea, anorexia, headache, dizziness, sensorimotor neuropathy, decreased urination, arrhythmia, infection. Zinc excretion doubles during the administration of DMSA. Patients must be kept hydrated as renal function can be compromised. For the above described reasons in all good conscious we can not recommend the use of DMSA for the treatment of mercury toxic pediatric patients. Approaching the fragile brain architecture of young children with autism, PDD and seizure disorders brings about tremendous responsibility in protecting the children from invasive interventions that risk alteration in brain function. Hair Analysis For Diagnosis and Treatment First, a determination must be made if, in fact, there is a heavy metal burden and if so specifically which heavy metals are involved such as aluminum, mercury, lead or others. This is the reason why hair analysis is a recommended initial screen. At this time we only advise two labs for this determination. Trace Elements in Austin, Texas and Analytical Research in Arizona. Both of these labs do not wash the hair samples prior to analysis. This is a key factor to proper interpretation of the other nontoxic minerals. Other labs would likely give proper heavy metal results, but the interpretation of the other minerals is key to an effective supplementation program. Chelation removes other minerals aside from mercury and these must be replaced properly if one wished to avoid complications. Establishing Metabolic Stability Prior To Detoxification One must be relatively healthy to sustain the process of detoxification. Once metabolic stability is established physicians often find that gentle biological interventions clear heavy metal burdens without the need for medication that holds the potential risk of negative side effects or merely redistribution of heavy metals. Clearing heavy metals may be approached by first reestablishing the mineral base, supporting biliary function/ digestion, insuring the patient is properly hydrated (children with autism are frequently dehydrated), and most importantly supporting hepatic function and metabolism Adults with heavy metal toxicity generally have significant suppression of omega 6 arachidonic acid and a significant elevation of very long chain fatty acids (Kane) as the cellular impact of heavy metals burdens block receptor sites such as G proteins and ultimately suppress the beta oxidation of lipids and cellular respiration. Children with autism consistently present with an elevation of VLCFAs However, red cell lipid levels of arachidonic are variable, elevated in some patients while deeply suppressed in others. Dietary Fat Intervention Must Be Considered Administration of fish oils suppresses omega 6 and structural lipids and this will suppress the production of arachidonic acid. To balance fat metabolism it is crucial to stabilize omega 6 fatty acids and arachidonic acid before introducing omega 3 lipids. Patient outcomes may be compromised if one uses fish oils prior to omega 6 fatty acids. The omega 6 fatty acid of choice would be evening primrose oil. Additionally, supporting the digestion of fats with bile salts and lipase is frequently required to maximize fat absorption and digestion. Japan and Mercury Exposure Example The impact of Hg upon human health was brought to light in the mid-50s with the Minamata disaster in Japan. As noted in the documentary 'Message to Minamata to the World' the impact of Hg is devastating, most prominently to the CNS. Interestingly, autistic behavior can observed in the documentary of Minamata children in original footage after the disaster. In 1993 Kane found an interesting correlation in the literature between autism and Hg with the occurrence of autism presenting in adulthood occurring in Japan. The presentation of autism in these individuals was linked to ornithine transcarbamylase deficiency, the most common urea cycle defect. Damage to this enzyme can occur with exposure to mercury. Low levels of ornithine transcarbamylase (OTC) leads to states of hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia, critical issues in states of epilepsy and autism. The often spacy, confused behavior 'brain fog' that is frequently observed in these disorders may be attributed states of hyperammonemia as ammonia reaches the brain. Suggested treatment of mildly suppressed levels of OTC includes sodium benzoate and phenylacetate. However, Kane and other clinicians have observed positive clinical usefulness of Ca/Mg butyrate, digestive intervention targeted to biliary flow, appropriate buffers, and stabilization of electrolytes and the trace mineral base. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 I also don't want to start a new war going on, but in recent times (though I can't remember if it was on this list) there has been a great deal of discussion about the credentials of one of these authors. I think this needs to be looked at with caution. There are many new members on this list that may not be aware of those discussions. Judy -----Original Message-----From: jcsinmd@... [mailto:jcsinmd@...]Sent: Sunday, October 01, 2000 3:52 PM egroupsSubject: [ ] DMSA/LA:Another ViewTaken from: http://www.mercola.com/2000/oct/1/mercury_autism.htmAutism and Mercury Detoxification P. Kane, Ph.D. and J. Mercola, D.O. Recently, it has been proposed that autism may be the aftermath of exposure to mercury such as ethyl mercury used as a preservative, thimerosal,in pediatric vaccinations. The article in this newsletter issue reviews this evidence. Currently Recommend Pediatric Mercury ProtocolThe protocol is always being improved. Drs. Klinghardt, Kane and Mercola revised this in September 2000 and the most current recommendationcan be found by clicking here. Small changes are likely to be regularlyposted but we will likely revise the protocol in December when we all are presenters at the Healing Your Brain 2000 Seminar. We currently are planning hold a one day workshop at the American Academy of Environmental Medicine to invite some of the top clinicians inmercury detoxification to further improve the program. Additionally, Wayne Obie, of TalkInternational.com is planning on facilitating an international collaboration on a revised mercury detoxification program.What is DMSA and Why Don't We Recommend It?DMSA is a FDA currently approved drug. It is a mixed disulfide inwhich each of the sulfur atoms is in disulfide linkage with a cysteine molecule forming water soluble chelates which increases the urinary excretion of lead.There are a number of physicians who have started to use DMSA toremove the mercury from children with autism. The dose used for mercury detoxification is much lower than that for lead and many children seem to have received benefit from this approach.A time released DMSA is being used for 7 days on, 7 days off or 3days on, 4 days off for an extended period of time (up to 6 months).However, some natural medicine clinicians have some serious concerns about the use of DMSA. There have been cases of:seizures increased self-stimming and compromised central nervous system function in some children. DMSA and Mercury Redistribution To The BrainIt appears that DMSA and lipoic acid can create tissue redistribution of mercury as decreasing Hg levels in the kidney (the organ accumulating Hg most abundantly) increases Hg concentrations of Hg in blood, brain, lung, heart, muscle and liver (Gregus et al). Natural medical physicians throughout the US have reported MSsymptoms in adults and intractable seizures in pediatric patients with high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or Succimer. Other Problems With DMSAExtended use of DMSA can cause mild to moderate neutropenia with increased SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase andBlood Urea Nitrogen (BUN). Adverse reactions to DMSA include ataxia,convulsions, rash, nausea, diarrhea, anorexia, headache, dizziness, sensorimotor neuropathy, decreased urination, arrhythmia, infection. Zinc excretion doubles during the administration of DMSA. Patients must be kept hydrated as renal function can be compromised. For the above described reasons in all good conscious we can not recommend the use of DMSA for the treatment of mercury toxic pediatric patients.Approaching the fragile brain architecture of young children with autism, PDD and seizure disorders brings about tremendous responsibility in protecting the children from invasive interventions that risk alteration inbrain function. Hair Analysis For Diagnosis and TreatmentFirst, a determination must be made if, in fact, there is a heavymetal burden and if so specifically which heavy metals are involved such as aluminum, mercury, lead or others.This is the reason why hair analysis is a recommended initial screen. At this time we only advise two labs for this determination. Trace Elementsin Austin, Texas and Analytical Research in Arizona. Both of these labs do not wash the hair samples prior to analysis.This is a key factor to proper interpretation of the other nontoxic minerals.Other labs would likely give proper heavy metal results, but the interpretation of the other minerals is key to an effective supplementation program. Chelation removes other minerals aside from mercury andthese must be replaced properly if one wished to avoid complications.Establishing Metabolic Stability Prior To DetoxificationOne must be relatively healthy to sustain the process of detoxification. Once metabolic stability is established physicians often find that gentle biological interventions clear heavy metal burdens without the needfor medication that holds the potential risk of negative side effects or merely redistribution of heavy metals. Clearing heavy metals may be approached by first reestablishing the mineral base, supporting biliary function/ digestion, insuring the patient is properly hydrated (children with autism are frequently dehydrated),and most importantly supporting hepatic function and metabolismAdults with heavy metal toxicity generally have significantsuppression of omega 6 arachidonic acid and a significant elevation of very longchain fatty acids (Kane) as the cellular impact of heavy metals burdens block receptor sites such as G proteins and ultimately suppress the beta oxidationof lipids and cellular respiration. Children with autism consistently present with an elevation of VLCFAs However, red cell lipid levels of arachidonic are variable, elevatedin some patients while deeply suppressed in others. Dietary Fat Intervention Must Be ConsideredAdministration of fish oils suppresses omega 6 and structural lipids and this will suppress the production of arachidonic acid. To balance fat metabolism it is crucial to stabilize omega 6 fatty acids and arachidonic acid before introducing omega 3 lipids. Patient outcomes may be compromised if one uses fish oils prior to omega 6 fatty acids. The omega 6 fatty acid of choice would be eveningprimrose oil. Additionally, supporting the digestion of fats with bile salts and lipase is frequently required to maximize fat absorption and digestion.Japan and Mercury Exposure ExampleThe impact of Hg upon human health was brought to light in themid-50s with the Minamata disaster in Japan. As noted in the documentary 'Messageto Minamata to the World' the impact of Hg is devastating, most prominently to the CNS. Interestingly, autistic behavior can observed in the documentary of Minamata children in original footage after the disaster. In 1993 Kane found an interesting correlation in the literaturebetween autism and Hg with the occurrence of autism presenting in adulthood occurring in Japan. The presentation of autism in these individuals was linkedto ornithine transcarbamylase deficiency, the most common urea cycle defect. Damage to this enzyme can occur with exposure to mercury. Low levels of ornithine transcarbamylase (OTC) leads to states of hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia, critical issues in states of epilepsy and autism. The often spacy, confused behavior 'brain fog' that is frequently observed in these disordersmay be attributed states of hyperammonemia as ammonia reaches the brain. Suggested treatment of mildly suppressed levels of OTC includessodium benzoate and phenylacetate. However, Kane and other clinicians have observed positive clinical usefulness of Ca/Mg butyrate, digestiveintervention targeted to biliary flow, appropriate buffers, and stabilization of electrolytes and the trace mineral base. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 ala FDA, I have to wonder if they don't invest in DMPS. Notice the first potential side effect to DMSA they list is "seizures". Sounds like a scare tactic. RE: [ ] DMSA/LA:Another View I also don't want to start a new war going on, but in recent times (though I can't remember if it was on this list) there has been a great deal of discussion about the credentials of one of these authors. I think this needs to be looked at with caution. There are many new members on this list that may not be aware of those discussions. Judy -----Original Message-----From: jcsinmd@... [mailto:jcsinmd@...]Sent: Sunday, October 01, 2000 3:52 PM egroupsSubject: [ ] DMSA/LA:Another ViewTaken from: http://www.mercola.com/2000/oct/1/mercury_autism.htmAutism and Mercury Detoxification P. Kane, Ph.D. and J. Mercola, D.O. Recently, it has been proposed that autism may be the aftermath of exposure to mercury such as ethyl mercury used as a preservative, thimerosal,in pediatric vaccinations. The article in this newsletter issue reviews this evidence. Currently Recommend Pediatric Mercury ProtocolThe protocol is always being improved. Drs. Klinghardt, Kane and Mercola revised this in September 2000 and the most current recommendationcan be found by clicking here. Small changes are likely to be regularlyposted but we will likely revise the protocol in December when we all are presenters at the Healing Your Brain 2000 Seminar. We currently are planning hold a one day workshop at the American Academy of Environmental Medicine to invite some of the top clinicians inmercury detoxification to further improve the program. Additionally, Wayne Obie, of TalkInternational.com is planning on facilitating an international collaboration on a revised mercury detoxification program.What is DMSA and Why Don't We Recommend It?DMSA is a FDA currently approved drug. It is a mixed disulfide inwhich each of the sulfur atoms is in disulfide linkage with a cysteine molecule forming water soluble chelates which increases the urinary excretion of lead.There are a number of physicians who have started to use DMSA toremove the mercury from children with autism. The dose used for mercury detoxification is much lower than that for lead and many children seem to have received benefit from this approach.A time released DMSA is being used for 7 days on, 7 days off or 3days on, 4 days off for an extended period of time (up to 6 months).However, some natural medicine clinicians have some serious concerns about the use of DMSA. There have been cases of:seizures increased self-stimming and compromised central nervous system function in some children. DMSA and Mercury Redistribution To The BrainIt appears that DMSA and lipoic acid can create tissue redistribution of mercury as decreasing Hg levels in the kidney (the organ accumulating Hg most abundantly) increases Hg concentrations of Hg in blood, brain, lung, heart, muscle and liver (Gregus et al). Natural medical physicians throughout the US have reported MSsymptoms in adults and intractable seizures in pediatric patients with high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or Succimer. Other Problems With DMSAExtended use of DMSA can cause mild to moderate neutropenia with increased SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase andBlood Urea Nitrogen (BUN). Adverse reactions to DMSA include ataxia,convulsions, rash, nausea, diarrhea, anorexia, headache, dizziness, sensorimotor neuropathy, decreased urination, arrhythmia, infection. Zinc excretion doubles during the administration of DMSA. Patients must be kept hydrated as renal function can be compromised. For the above described reasons in all good conscious we can not recommend the use of DMSA for the treatment of mercury toxic pediatric patients.Approaching the fragile brain architecture of young children with autism, PDD and seizure disorders brings about tremendous responsibility in protecting the children from invasive interventions that risk alteration inbrain function. Hair Analysis For Diagnosis and TreatmentFirst, a determination must be made if, in fact, there is a heavymetal burden and if so specifically which heavy metals are involved such as aluminum, mercury, lead or others.This is the reason why hair analysis is a recommended initial screen. At this time we only advise two labs for this determination. Trace Elementsin Austin, Texas and Analytical Research in Arizona. Both of these labs do not wash the hair samples prior to analysis.This is a key factor to proper interpretation of the other nontoxic minerals.Other labs would likely give proper heavy metal results, but the interpretation of the other minerals is key to an effective supplementation program. Chelation removes other minerals aside from mercury andthese must be replaced properly if one wished to avoid complications.Establishing Metabolic Stability Prior To DetoxificationOne must be relatively healthy to sustain the process of detoxification. Once metabolic stability is established physicians often find that gentle biological interventions clear heavy metal burdens without the needfor medication that holds the potential risk of negative side effects or merely redistribution of heavy metals. Clearing heavy metals may be approached by first reestablishing the mineral base, supporting biliary function/ digestion, insuring the patient is properly hydrated (children with autism are frequently dehydrated),and most importantly supporting hepatic function and metabolismAdults with heavy metal toxicity generally have significantsuppression of omega 6 arachidonic acid and a significant elevation of very longchain fatty acids (Kane) as the cellular impact of heavy metals burdens block receptor sites such as G proteins and ultimately suppress the beta oxidationof lipids and cellular respiration. Children with autism consistently present with an elevation of VLCFAs However, red cell lipid levels of arachidonic are variable, elevatedin some patients while deeply suppressed in others. Dietary Fat Intervention Must Be ConsideredAdministration of fish oils suppresses omega 6 and structural lipids and this will suppress the production of arachidonic acid. To balance fat metabolism it is crucial to stabilize omega 6 fatty acids and arachidonic acid before introducing omega 3 lipids. Patient outcomes may be compromised if one uses fish oils prior to omega 6 fatty acids. The omega 6 fatty acid of choice would be eveningprimrose oil. Additionally, supporting the digestion of fats with bile salts and lipase is frequently required to maximize fat absorption and digestion.Japan and Mercury Exposure ExampleThe impact of Hg upon human health was brought to light in themid-50s with the Minamata disaster in Japan. As noted in the documentary 'Messageto Minamata to the World' the impact of Hg is devastating, most prominently to the CNS. Interestingly, autistic behavior can observed in the documentary of Minamata children in original footage after the disaster. In 1993 Kane found an interesting correlation in the literaturebetween autism and Hg with the occurrence of autism presenting in adulthood occurring in Japan. The presentation of autism in these individuals was linkedto ornithine transcarbamylase deficiency, the most common urea cycle defect. Damage to this enzyme can occur with exposure to mercury. Low levels of ornithine transcarbamylase (OTC) leads to states of hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia, critical issues in states of epilepsy and autism. The often spacy, confused behavior 'brain fog' that is frequently observed in these disordersmay be attributed states of hyperammonemia as ammonia reaches the brain. Suggested treatment of mildly suppressed levels of OTC includessodium benzoate and phenylacetate. However, Kane and other clinicians have observed positive clinical usefulness of Ca/Mg butyrate, digestiveintervention targeted to biliary flow, appropriate buffers, and stabilization of electrolytes and the trace mineral base. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 OH NO NOT THIS AGAIN? I POSTED THIS BELOW FOR INFORMATION ONLY. I AM SO GLAD THAT ANDY HAS POSTED ABOUT THE DANGERS OF DMPS. THAT WILL MAKE THE FEDERAL GOVERNMENT SO MUCH MORE CONFIDENT IN THEIR POSITION AGAINST DMPS. PLEASE TAKE WHAT ANDY SAYS TO YOUR DOCTOR. DO NOT TAKE THE FEDERAL INFORMATION, BECAUSE I AM SURE THAT YOUR DOCTOR WILL BE MUCH MORE INTERESTED IN WHAT ANDY SAYS THAN WHAT THE FEDERAL GOVERNMENT SAYS. > Oh no, not this again!! > > Folks, DMPS has not been approved for use in children! And Andy has > posted quite a lot about the dangers of DMPS. > > Hey, even our pediatrician feels VERY comfortable about us using DMSA > under our chelating doctor's direction, and the ped. is a VERY > CONSERVATIVE man. > > Some of the statements made below have been taken out of context, and > some are just NOT TRUE. > > The post below makes DMSA chelation sound very dangerous. In fact, > DMSA is VERY SAFE. When I asked the doctor who is treating Kenny > about this " seizure risk " this doctor said that there is absolutely no > evidence of this. In point of fact, the risks of using DMPS are MUCH > HIGHER. > > The post below states: > > " Natural medical physicians throughout the US have reported MS > symptoms in adults and intractable seizures in pediatric patients with > high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), > Chemet or Succimer. " > > However, the chelation protocol being used by reputable doctors is NOT > a high dose of DMSA. Even aspirin can be dangerous if taken in high > doses for a long period of time. > > Which all points up the fact that BEFORE you do anything with your > child, make sure you have thoroughly RESEARCHED the approach your > doctor suggests you take with your child. Ask lots of questions, and > make sure your doctor KNOWS what s/he is doing! > > (Cary, NC) > persistentC@b... > > [ ] DMSA/LA:Another View > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > Autism and Mercury Detoxification > P. Kane, Ph.D. and J. Mercola, D.O. > > Recently, it has been proposed that autism may be the aftermath of > exposure > to mercury such as ethyl mercury used as a preservative, thimerosal, > in > pediatric vaccinations. The article in this newsletter issue reviews > this > evidence. > > Currently Recommend Pediatric Mercury Protocol > > The protocol is always being improved. Drs. Klinghardt, Kane and > Mercola > revised this in September 2000 and the most current recommendation > can > be > found by clicking here. Small changes are likely to be regularly > posted > but > we will likely revise the protocol in December when we all are > presenters at > the Healing Your Brain 2000 Seminar. > > We currently are planning hold a one day workshop at the American > Academy of > Environmental Medicine to invite some of the top clinicians in > mercury > detoxification to further improve the program. Additionally, Wayne > Obie, of > TalkInternational.com is planning on facilitating an international > collaboration on a revised mercury detoxification program. > > What is DMSA and Why Don't We Recommend It? > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > which > each > of the sulfur atoms is in disulfide linkage with a cysteine molecule > forming > water soluble chelates which increases the urinary excretion of lead. > > There are a number of physicians who have started to use DMSA to > remove > the > mercury from children with autism. The dose used for mercury > detoxification > is much lower than that for lead and many children seem to have > received > benefit from this approach. > > A time released DMSA is being used for 7 days on, 7 days off or 3 > days > on, 4 > days off for an extended period of time (up to 6 months). > > However, some natural medicine clinicians have some serious concerns > about > the use of DMSA. There have been cases of: > > > seizures > > increased self-stimming > > and compromised central nervous system function in some children. > > > DMSA and Mercury Redistribution To The Brain > > It appears that DMSA and lipoic acid can create tissue redistribution > of > mercury as decreasing Hg levels in the kidney (the organ accumulating > Hg most > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > heart, > muscle and liver (Gregus et al). > > Natural medical physicians throughout the US have reported MS > symptoms > in > adults and intractable seizures in pediatric patients with high dose > and > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > Succimer. > > Other Problems With DMSA > > Extended use of DMSA can cause mild to moderate neutropenia with > increased > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > Blood > Urea > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > convulsions, > rash, > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > neuropathy, > decreased urination, arrhythmia, infection. Zinc excretion doubles > during the > administration of DMSA. Patients must be kept hydrated as renal > function can > be compromised. > > For the above described reasons in all good conscious we can not > recommend > the use of DMSA for the treatment of mercury toxic pediatric patients. > > Approaching the fragile brain architecture of young children with > autism, PDD > and seizure disorders brings about tremendous responsibility in > protecting > the children from invasive interventions that risk alteration in > brain > function. > > Hair Analysis For Diagnosis and Treatment > > First, a determination must be made if, in fact, there is a heavy > metal > burden and if so specifically which heavy metals are involved such as > aluminum, mercury, lead or others. > > This is the reason why hair analysis is a recommended initial screen. > At this > time we only advise two labs for this determination. Trace Elements > in > Austin, Texas and Analytical Research in Arizona. > > Both of these labs do not wash the hair samples prior to analysis. > This > is a > key factor to proper interpretation of the other nontoxic minerals. > > Other labs would likely give proper heavy metal results, but the > interpretation of the other minerals is key to an effective > supplementation > program. Chelation removes other minerals aside from mercury and > these > must > be replaced properly if one wished to avoid complications. > > Establishing Metabolic Stability Prior To Detoxification > > One must be relatively healthy to sustain the process of > detoxification. Once > metabolic stability is established physicians often find that gentle > biological interventions clear heavy metal burdens without the need > for > medication that holds the potential risk of negative side effects or > merely > redistribution of heavy metals. > > Clearing heavy metals may be approached by first reestablishing the > mineral > base, supporting biliary function/ digestion, insuring the patient is > properly hydrated (children with autism are frequently dehydrated), > and > most > importantly supporting hepatic function and metabolism > > Adults with heavy metal toxicity generally have significant > suppression > of > omega 6 arachidonic acid and a significant elevation of very long > chain > fatty > acids (Kane) as the cellular impact of heavy metals burdens block > receptor > sites such as G proteins and ultimately suppress the beta oxidation > of > lipids > and cellular respiration. > > Children with autism consistently present with an elevation of VLCFAs > However, red cell lipid levels of arachidonic are variable, elevated > in > some > patients while deeply suppressed in others. > > Dietary Fat Intervention Must Be Considered > > Administration of fish oils suppresses omega 6 and structural lipids > and this > will suppress the production of arachidonic acid. To balance fat > metabolism > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > before > introducing omega 3 lipids. > > Patient outcomes may be compromised if one uses fish oils prior to > omega 6 > fatty acids. The omega 6 fatty acid of choice would be evening > primrose > oil. > Additionally, supporting the digestion of fats with bile salts and > lipase is > frequently required to maximize fat absorption and digestion. > > Japan and Mercury Exposure Example > > The impact of Hg upon human health was brought to light in the > mid-50s > with > the Minamata disaster in Japan. As noted in the documentary 'Message > to > Minamata to the World' the impact of Hg is devastating, most > prominently to > the CNS. Interestingly, autistic behavior can observed in the > documentary of > Minamata children in original footage after the disaster. > > In 1993 Kane found an interesting correlation in the literature > between > autism and Hg with the occurrence of autism presenting in adulthood > occurring > in Japan. The presentation of autism in these individuals was linked > to > ornithine transcarbamylase deficiency, the most common urea cycle > defect. > Damage to this enzyme can occur with exposure to mercury. > > Low levels of ornithine transcarbamylase (OTC) leads to states of > hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia, > critical issues in states of epilepsy and autism. The often spacy, > confused > behavior 'brain fog' that is frequently observed in these disorders > may > be > attributed states of hyperammonemia as ammonia reaches the brain. > > Suggested treatment of mildly suppressed levels of OTC includes > sodium > benzoate and phenylacetate. However, Kane and other clinicians have > observed > positive clinical usefulness of Ca/Mg butyrate, digestive > intervention > targeted to biliary flow, appropriate buffers, and stabilization of > electrolytes and the trace mineral base. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Good advice, . I would like to add that you probably also want to make sure your " doctor " is really a doctor. Ricci <persistentC@b...> wrote: > Which all points up the fact that BEFORE you do anything with your > child, make sure you have thoroughly RESEARCHED the approach your > doctor suggests you take with your child. Ask lots of questions, and > make sure your doctor KNOWS what s/he is doing! > > (Cary, NC) > persistentC@b... > > [ ] DMSA/LA:Another View > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > Autism and Mercury Detoxification > P. Kane, Ph.D. and J. Mercola, D.O. > > Recently, it has been proposed that autism may be the aftermath of > exposure > to mercury such as ethyl mercury used as a preservative, thimerosal, > in > pediatric vaccinations. The article in this newsletter issue reviews > this > evidence. > > Currently Recommend Pediatric Mercury Protocol > > The protocol is always being improved. Drs. Klinghardt, Kane and > Mercola > revised this in September 2000 and the most current recommendation > can > be > found by clicking here. Small changes are likely to be regularly > posted > but > we will likely revise the protocol in December when we all are > presenters at > the Healing Your Brain 2000 Seminar. > > We currently are planning hold a one day workshop at the American > Academy of > Environmental Medicine to invite some of the top clinicians in > mercury > detoxification to further improve the program. Additionally, Wayne > Obie, of > TalkInternational.com is planning on facilitating an international > collaboration on a revised mercury detoxification program. > > What is DMSA and Why Don't We Recommend It? > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > which > each > of the sulfur atoms is in disulfide linkage with a cysteine molecule > forming > water soluble chelates which increases the urinary excretion of lead. > > There are a number of physicians who have started to use DMSA to > remove > the > mercury from children with autism. The dose used for mercury > detoxification > is much lower than that for lead and many children seem to have > received > benefit from this approach. > > A time released DMSA is being used for 7 days on, 7 days off or 3 > days > on, 4 > days off for an extended period of time (up to 6 months). > > However, some natural medicine clinicians have some serious concerns > about > the use of DMSA. There have been cases of: > > > seizures > > increased self-stimming > > and compromised central nervous system function in some children. > > > DMSA and Mercury Redistribution To The Brain > > It appears that DMSA and lipoic acid can create tissue redistribution > of > mercury as decreasing Hg levels in the kidney (the organ accumulating > Hg most > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > heart, > muscle and liver (Gregus et al). > > Natural medical physicians throughout the US have reported MS > symptoms > in > adults and intractable seizures in pediatric patients with high dose > and > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > Succimer. > > Other Problems With DMSA > > Extended use of DMSA can cause mild to moderate neutropenia with > increased > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > Blood > Urea > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > convulsions, > rash, > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > neuropathy, > decreased urination, arrhythmia, infection. Zinc excretion doubles > during the > administration of DMSA. Patients must be kept hydrated as renal > function can > be compromised. > > For the above described reasons in all good conscious we can not > recommend > the use of DMSA for the treatment of mercury toxic pediatric patients. > > Approaching the fragile brain architecture of young children with > autism, PDD > and seizure disorders brings about tremendous responsibility in > protecting > the children from invasive interventions that risk alteration in > brain > function. > > Hair Analysis For Diagnosis and Treatment > > First, a determination must be made if, in fact, there is a heavy > metal > burden and if so specifically which heavy metals are involved such as > aluminum, mercury, lead or others. > > This is the reason why hair analysis is a recommended initial screen. > At this > time we only advise two labs for this determination. Trace Elements > in > Austin, Texas and Analytical Research in Arizona. > > Both of these labs do not wash the hair samples prior to analysis. > This > is a > key factor to proper interpretation of the other nontoxic minerals. > > Other labs would likely give proper heavy metal results, but the > interpretation of the other minerals is key to an effective > supplementation > program. Chelation removes other minerals aside from mercury and > these > must > be replaced properly if one wished to avoid complications. > > Establishing Metabolic Stability Prior To Detoxification > > One must be relatively healthy to sustain the process of > detoxification. Once > metabolic stability is established physicians often find that gentle > biological interventions clear heavy metal burdens without the need > for > medication that holds the potential risk of negative side effects or > merely > redistribution of heavy metals. > > Clearing heavy metals may be approached by first reestablishing the > mineral > base, supporting biliary function/ digestion, insuring the patient is > properly hydrated (children with autism are frequently dehydrated), > and > most > importantly supporting hepatic function and metabolism > > Adults with heavy metal toxicity generally have significant > suppression > of > omega 6 arachidonic acid and a significant elevation of very long > chain > fatty > acids (Kane) as the cellular impact of heavy metals burdens block > receptor > sites such as G proteins and ultimately suppress the beta oxidation > of > lipids > and cellular respiration. > > Children with autism consistently present with an elevation of VLCFAs > However, red cell lipid levels of arachidonic are variable, elevated > in > some > patients while deeply suppressed in others. > > Dietary Fat Intervention Must Be Considered > > Administration of fish oils suppresses omega 6 and structural lipids > and this > will suppress the production of arachidonic acid. To balance fat > metabolism > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > before > introducing omega 3 lipids. > > Patient outcomes may be compromised if one uses fish oils prior to > omega 6 > fatty acids. The omega 6 fatty acid of choice would be evening > primrose > oil. > Additionally, supporting the digestion of fats with bile salts and > lipase is > frequently required to maximize fat absorption and digestion. > > Japan and Mercury Exposure Example > > The impact of Hg upon human health was brought to light in the > mid-50s > with > the Minamata disaster in Japan. As noted in the documentary 'Message > to > Minamata to the World' the impact of Hg is devastating, most > prominently to > the CNS. Interestingly, autistic behavior can observed in the > documentary of > Minamata children in original footage after the disaster. > > In 1993 Kane found an interesting correlation in the literature > between > autism and Hg with the occurrence of autism presenting in adulthood > occurring > in Japan. The presentation of autism in these individuals was linked > to > ornithine transcarbamylase deficiency, the most common urea cycle > defect. > Damage to this enzyme can occur with exposure to mercury. > > Low levels of ornithine transcarbamylase (OTC) leads to states of > hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia, > critical issues in states of epilepsy and autism. The often spacy, > confused > behavior 'brain fog' that is frequently observed in these disorders > may > be > attributed states of hyperammonemia as ammonia reaches the brain. > > Suggested treatment of mildly suppressed levels of OTC includes > sodium > benzoate and phenylacetate. However, Kane and other clinicians have > observed > positive clinical usefulness of Ca/Mg butyrate, digestive > intervention > targeted to biliary flow, appropriate buffers, and stabilization of > electrolytes and the trace mineral base. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 , What is the source of all this animosity towards Andy? Actually, it's none of my business. But it's very ugly and I think everyone else would agree with me when I tell you that reading your jabs and snide remarks is disturbing and uncomfortable. Please do keep them to yourself. Otherwise, we are all interested in what you have to say. Okay? Thanks, [ ] DMSA/LA:Another View > > > > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > > > > > Autism and Mercury Detoxification > > P. Kane, Ph.D. and J. Mercola, D.O. > > > > Recently, it has been proposed that autism may be the aftermath of > > exposure > > to mercury such as ethyl mercury used as a preservative, thimerosal, > > in > > pediatric vaccinations. The article in this newsletter issue reviews > > this > > evidence. > > > > Currently Recommend Pediatric Mercury Protocol > > > > The protocol is always being improved. Drs. Klinghardt, Kane and > > Mercola > > revised this in September 2000 and the most current recommendation > > can > > be > > found by clicking here. Small changes are likely to be regularly > > posted > > but > > we will likely revise the protocol in December when we all are > > presenters at > > the Healing Your Brain 2000 Seminar. > > > > We currently are planning hold a one day workshop at the American > > Academy of > > Environmental Medicine to invite some of the top clinicians in > > mercury > > detoxification to further improve the program. Additionally, Wayne > > Obie, of > > TalkInternational.com is planning on facilitating an international > > collaboration on a revised mercury detoxification program. > > > > What is DMSA and Why Don't We Recommend It? > > > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > > which > > each > > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > forming > > water soluble chelates which increases the urinary excretion of > lead. > > > > There are a number of physicians who have started to use DMSA to > > remove > > the > > mercury from children with autism. The dose used for mercury > > detoxification > > is much lower than that for lead and many children seem to have > > received > > benefit from this approach. > > > > A time released DMSA is being used for 7 days on, 7 days off or 3 > > days > > on, 4 > > days off for an extended period of time (up to 6 months). > > > > However, some natural medicine clinicians have some serious concerns > > about > > the use of DMSA. There have been cases of: > > > > > > seizures > > > > increased self-stimming > > > > and compromised central nervous system function in some children. > > > > > > DMSA and Mercury Redistribution To The Brain > > > > It appears that DMSA and lipoic acid can create tissue > redistribution > > of > > mercury as decreasing Hg levels in the kidney (the organ > accumulating > > Hg most > > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > heart, > > muscle and liver (Gregus et al). > > > > Natural medical physicians throughout the US have reported MS > > symptoms > > in > > adults and intractable seizures in pediatric patients with high dose > > and > > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > > Succimer. > > > > Other Problems With DMSA > > > > Extended use of DMSA can cause mild to moderate neutropenia with > > increased > > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > > Blood > > Urea > > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > > convulsions, > > rash, > > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > > neuropathy, > > decreased urination, arrhythmia, infection. Zinc excretion doubles > > during the > > administration of DMSA. Patients must be kept hydrated as renal > > function can > > be compromised. > > > > For the above described reasons in all good conscious we can not > > recommend > > the use of DMSA for the treatment of mercury toxic pediatric > patients. > > > > Approaching the fragile brain architecture of young children with > > autism, PDD > > and seizure disorders brings about tremendous responsibility in > > protecting > > the children from invasive interventions that risk alteration in > > brain > > function. > > > > Hair Analysis For Diagnosis and Treatment > > > > First, a determination must be made if, in fact, there is a heavy > > metal > > burden and if so specifically which heavy metals are involved such > as > > aluminum, mercury, lead or others. > > > > This is the reason why hair analysis is a recommended initial > screen. > > At this > > time we only advise two labs for this determination. Trace Elements > > in > > Austin, Texas and Analytical Research in Arizona. > > > > Both of these labs do not wash the hair samples prior to analysis. > > This > > is a > > key factor to proper interpretation of the other nontoxic minerals. > > > > Other labs would likely give proper heavy metal results, but the > > interpretation of the other minerals is key to an effective > > supplementation > > program. Chelation removes other minerals aside from mercury and > > these > > must > > be replaced properly if one wished to avoid complications. > > > > Establishing Metabolic Stability Prior To Detoxification > > > > One must be relatively healthy to sustain the process of > > detoxification. Once > > metabolic stability is established physicians often find that gentle > > biological interventions clear heavy metal burdens without the need > > for > > medication that holds the potential risk of negative side effects or > > merely > > redistribution of heavy metals. > > > > Clearing heavy metals may be approached by first reestablishing the > > mineral > > base, supporting biliary function/ digestion, insuring the patient > is > > properly hydrated (children with autism are frequently dehydrated), > > and > > most > > importantly supporting hepatic function and metabolism > > > > Adults with heavy metal toxicity generally have significant > > suppression > > of > > omega 6 arachidonic acid and a significant elevation of very long > > chain > > fatty > > acids (Kane) as the cellular impact of heavy metals burdens block > > receptor > > sites such as G proteins and ultimately suppress the beta oxidation > > of > > lipids > > and cellular respiration. > > > > Children with autism consistently present with an elevation of > VLCFAs > > However, red cell lipid levels of arachidonic are variable, elevated > > in > > some > > patients while deeply suppressed in others. > > > > Dietary Fat Intervention Must Be Considered > > > > Administration of fish oils suppresses omega 6 and structural lipids > > and this > > will suppress the production of arachidonic acid. To balance fat > > metabolism > > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > > before > > introducing omega 3 lipids. > > > > Patient outcomes may be compromised if one uses fish oils prior to > > omega 6 > > fatty acids. The omega 6 fatty acid of choice would be evening > > primrose > > oil. > > Additionally, supporting the digestion of fats with bile salts and > > lipase is > > frequently required to maximize fat absorption and digestion. > > > > Japan and Mercury Exposure Example > > > > The impact of Hg upon human health was brought to light in the > > mid-50s > > with > > the Minamata disaster in Japan. As noted in the documentary 'Message > > to > > Minamata to the World' the impact of Hg is devastating, most > > prominently to > > the CNS. Interestingly, autistic behavior can observed in the > > documentary of > > Minamata children in original footage after the disaster. > > > > In 1993 Kane found an interesting correlation in the literature > > between > > autism and Hg with the occurrence of autism presenting in adulthood > > occurring > > in Japan. The presentation of autism in these individuals was linked > > to > > ornithine transcarbamylase deficiency, the most common urea cycle > > defect. > > Damage to this enzyme can occur with exposure to mercury. > > > > Low levels of ornithine transcarbamylase (OTC) leads to states of > > hyperammonemia, seizures and stroke. The enzyme OTC controls > ammonia, > > critical issues in states of epilepsy and autism. The often spacy, > > confused > > behavior 'brain fog' that is frequently observed in these disorders > > may > > be > > attributed states of hyperammonemia as ammonia reaches the brain. > > > > Suggested treatment of mildly suppressed levels of OTC includes > > sodium > > benzoate and phenylacetate. However, Kane and other clinicians have > > observed > > positive clinical usefulness of Ca/Mg butyrate, digestive > > intervention > > targeted to biliary flow, appropriate buffers, and stabilization of > > electrolytes and the trace mineral base. > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 , No matter what you say, DMPS is NOT APPROVED for use in children. I would hope that anybody who is starting chelation would find the expert doctors who know what they are doing and have them talk to their own doctors. Dr. Holmes will speak to any doctor who wishes to get information. I'm sure there are some other docs "in the know" who would do likewise. , one of the "experts" of that other post has masqueraded on this list as a doctor, and a father of an autistic child, and I suspect that that person is now on this list with yet another identity. (See if you can figure it out.) This person has a "high-level degree" which took only a few months to earn from a "University" that has been shut down by the government. (Cary, NC)persistentC@... [ ] DMSA/LA:Another View> > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm> > > > Autism and Mercury Detoxification> P. Kane, Ph.D. and J. Mercola, D.O.> > Recently, it has been proposed that autism may be the aftermath of> exposure> to mercury such as ethyl mercury used as a preservative, thimerosal,> in> pediatric vaccinations. The article in this newsletter issue reviews> this> evidence.> > Currently Recommend Pediatric Mercury Protocol> > The protocol is always being improved. Drs. Klinghardt, Kane and> Mercola> revised this in September 2000 and the most current recommendation> can> be> found by clicking here. Small changes are likely to be regularly> posted> but> we will likely revise the protocol in December when we all are> presenters at> the Healing Your Brain 2000 Seminar.> > We currently are planning hold a one day workshop at the American> Academy of> Environmental Medicine to invite some of the top clinicians in> mercury> detoxification to further improve the program. Additionally, Wayne> Obie, of> TalkInternational.com is planning on facilitating an international> collaboration on a revised mercury detoxification program.> > What is DMSA and Why Don't We Recommend It?> > DMSA is a FDA currently approved drug. It is a mixed disulfide in> which> each> of the sulfur atoms is in disulfide linkage with a cysteine molecule> forming> water soluble chelates which increases the urinary excretion of lead.> > There are a number of physicians who have started to use DMSA to> remove> the> mercury from children with autism. The dose used for mercury> detoxification> is much lower than that for lead and many children seem to have> received> benefit from this approach.> > A time released DMSA is being used for 7 days on, 7 days off or 3> days> on, 4> days off for an extended period of time (up to 6 months).> > However, some natural medicine clinicians have some serious concerns> about> the use of DMSA. There have been cases of:> > > seizures> > increased self-stimming> > and compromised central nervous system function in some children.> > > DMSA and Mercury Redistribution To The Brain> > It appears that DMSA and lipoic acid can create tissue redistribution> of> mercury as decreasing Hg levels in the kidney (the organ accumulating> Hg most> abundantly) increases Hg concentrations of Hg in blood, brain, lung,> heart,> muscle and liver (Gregus et al).> > Natural medical physicians throughout the US have reported MS> symptoms> in> adults and intractable seizures in pediatric patients with high dose> and> extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or> Succimer.> > Other Problems With DMSA> > Extended use of DMSA can cause mild to moderate neutropenia with> increased> SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and> Blood> Urea> Nitrogen (BUN). Adverse reactions to DMSA include ataxia,> convulsions,> rash,> nausea, diarrhea, anorexia, headache, dizziness, sensorimotor> neuropathy,> decreased urination, arrhythmia, infection. Zinc excretion doubles> during the> administration of DMSA. Patients must be kept hydrated as renal> function can> be compromised.> > For the above described reasons in all good conscious we can not> recommend> the use of DMSA for the treatment of mercury toxic pediatric patients.> > Approaching the fragile brain architecture of young children with> autism, PDD> and seizure disorders brings about tremendous responsibility in> protecting> the children from invasive interventions that risk alteration in> brain> function.> > Hair Analysis For Diagnosis and Treatment> > First, a determination must be made if, in fact, there is a heavy> metal> burden and if so specifically which heavy metals are involved such as> aluminum, mercury, lead or others.> > This is the reason why hair analysis is a recommended initial screen.> At this> time we only advise two labs for this determination. Trace Elements> in> Austin, Texas and Analytical Research in Arizona.> > Both of these labs do not wash the hair samples prior to analysis.> This> is a> key factor to proper interpretation of the other nontoxic minerals.> > Other labs would likely give proper heavy metal results, but the> interpretation of the other minerals is key to an effective> supplementation> program. Chelation removes other minerals aside from mercury and> these> must> be replaced properly if one wished to avoid complications.> > Establishing Metabolic Stability Prior To Detoxification> > One must be relatively healthy to sustain the process of> detoxification. Once> metabolic stability is established physicians often find that gentle> biological interventions clear heavy metal burdens without the need> for> medication that holds the potential risk of negative side effects or> merely> redistribution of heavy metals.> > Clearing heavy metals may be approached by first reestablishing the> mineral> base, supporting biliary function/ digestion, insuring the patient is> properly hydrated (children with autism are frequently dehydrated),> and> most> importantly supporting hepatic function and metabolism> > Adults with heavy metal toxicity generally have significant> suppression> of> omega 6 arachidonic acid and a significant elevation of very long> chain> fatty> acids (Kane) as the cellular impact of heavy metals burdens block> receptor> sites such as G proteins and ultimately suppress the beta oxidation> of> lipids> and cellular respiration.> > Children with autism consistently present with an elevation of VLCFAs> However, red cell lipid levels of arachidonic are variable, elevated> in> some> patients while deeply suppressed in others.> > Dietary Fat Intervention Must Be Considered> > Administration of fish oils suppresses omega 6 and structural lipids> and this> will suppress the production of arachidonic acid. To balance fat> metabolism> it is crucial to stabilize omega 6 fatty acids and arachidonic acid> before> introducing omega 3 lipids.> > Patient outcomes may be compromised if one uses fish oils prior to> omega 6> fatty acids. The omega 6 fatty acid of choice would be evening> primrose> oil.> Additionally, supporting the digestion of fats with bile salts and> lipase is> frequently required to maximize fat absorption and digestion.> > Japan and Mercury Exposure Example> > The impact of Hg upon human health was brought to light in the> mid-50s> with> the Minamata disaster in Japan. As noted in the documentary 'Message> to> Minamata to the World' the impact of Hg is devastating, most> prominently to> the CNS. Interestingly, autistic behavior can observed in the> documentary of> Minamata children in original footage after the disaster.> > In 1993 Kane found an interesting correlation in the literature> between> autism and Hg with the occurrence of autism presenting in adulthood> occurring> in Japan. The presentation of autism in these individuals was linked> to> ornithine transcarbamylase deficiency, the most common urea cycle> defect.> Damage to this enzyme can occur with exposure to mercury.> > Low levels of ornithine transcarbamylase (OTC) leads to states of> hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia,> critical issues in states of epilepsy and autism. The often spacy,> confused> behavior 'brain fog' that is frequently observed in these disorders> may> be> attributed states of hyperammonemia as ammonia reaches the brain.> > Suggested treatment of mildly suppressed levels of OTC includes> sodium> benzoate and phenylacetate. However, Kane and other clinicians have> observed> positive clinical usefulness of Ca/Mg butyrate, digestive> intervention> targeted to biliary flow, appropriate buffers, and stabilization of> electrolytes and the trace mineral base.> > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 I don't know if there IS such a thing as the perfect doctor for us and our children. I'm talking with three doctors about this right now - an M.D., a D.O., and a psychiatrist and what do I look for? Someone who will go along with me. We parents look into these issues SO much more extensively than the doctors - they have tunnel vision. We look at ALL the possibilities with an open mind. [ ] DMSA/LA:Another View > > > > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > > > > > Autism and Mercury Detoxification > > P. Kane, Ph.D. and J. Mercola, D.O. > > > > Recently, it has been proposed that autism may be the aftermath of > > exposure > > to mercury such as ethyl mercury used as a preservative, thimerosal, > > in > > pediatric vaccinations. The article in this newsletter issue reviews > > this > > evidence. > > > > Currently Recommend Pediatric Mercury Protocol > > > > The protocol is always being improved. Drs. Klinghardt, Kane and > > Mercola > > revised this in September 2000 and the most current recommendation > > can > > be > > found by clicking here. Small changes are likely to be regularly > > posted > > but > > we will likely revise the protocol in December when we all are > > presenters at > > the Healing Your Brain 2000 Seminar. > > > > We currently are planning hold a one day workshop at the American > > Academy of > > Environmental Medicine to invite some of the top clinicians in > > mercury > > detoxification to further improve the program. Additionally, Wayne > > Obie, of > > TalkInternational.com is planning on facilitating an international > > collaboration on a revised mercury detoxification program. > > > > What is DMSA and Why Don't We Recommend It? > > > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > > which > > each > > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > forming > > water soluble chelates which increases the urinary excretion of > lead. > > > > There are a number of physicians who have started to use DMSA to > > remove > > the > > mercury from children with autism. The dose used for mercury > > detoxification > > is much lower than that for lead and many children seem to have > > received > > benefit from this approach. > > > > A time released DMSA is being used for 7 days on, 7 days off or 3 > > days > > on, 4 > > days off for an extended period of time (up to 6 months). > > > > However, some natural medicine clinicians have some serious concerns > > about > > the use of DMSA. There have been cases of: > > > > > > seizures > > > > increased self-stimming > > > > and compromised central nervous system function in some children. > > > > > > DMSA and Mercury Redistribution To The Brain > > > > It appears that DMSA and lipoic acid can create tissue > redistribution > > of > > mercury as decreasing Hg levels in the kidney (the organ > accumulating > > Hg most > > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > heart, > > muscle and liver (Gregus et al). > > > > Natural medical physicians throughout the US have reported MS > > symptoms > > in > > adults and intractable seizures in pediatric patients with high dose > > and > > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > > Succimer. > > > > Other Problems With DMSA > > > > Extended use of DMSA can cause mild to moderate neutropenia with > > increased > > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > > Blood > > Urea > > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > > convulsions, > > rash, > > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > > neuropathy, > > decreased urination, arrhythmia, infection. Zinc excretion doubles > > during the > > administration of DMSA. Patients must be kept hydrated as renal > > function can > > be compromised. > > > > For the above described reasons in all good conscious we can not > > recommend > > the use of DMSA for the treatment of mercury toxic pediatric > patients. > > > > Approaching the fragile brain architecture of young children with > > autism, PDD > > and seizure disorders brings about tremendous responsibility in > > protecting > > the children from invasive interventions that risk alteration in > > brain > > function. > > > > Hair Analysis For Diagnosis and Treatment > > > > First, a determination must be made if, in fact, there is a heavy > > metal > > burden and if so specifically which heavy metals are involved such > as > > aluminum, mercury, lead or others. > > > > This is the reason why hair analysis is a recommended initial > screen. > > At this > > time we only advise two labs for this determination. Trace Elements > > in > > Austin, Texas and Analytical Research in Arizona. > > > > Both of these labs do not wash the hair samples prior to analysis. > > This > > is a > > key factor to proper interpretation of the other nontoxic minerals. > > > > Other labs would likely give proper heavy metal results, but the > > interpretation of the other minerals is key to an effective > > supplementation > > program. Chelation removes other minerals aside from mercury and > > these > > must > > be replaced properly if one wished to avoid complications. > > > > Establishing Metabolic Stability Prior To Detoxification > > > > One must be relatively healthy to sustain the process of > > detoxification. Once > > metabolic stability is established physicians often find that gentle > > biological interventions clear heavy metal burdens without the need > > for > > medication that holds the potential risk of negative side effects or > > merely > > redistribution of heavy metals. > > > > Clearing heavy metals may be approached by first reestablishing the > > mineral > > base, supporting biliary function/ digestion, insuring the patient > is > > properly hydrated (children with autism are frequently dehydrated), > > and > > most > > importantly supporting hepatic function and metabolism > > > > Adults with heavy metal toxicity generally have significant > > suppression > > of > > omega 6 arachidonic acid and a significant elevation of very long > > chain > > fatty > > acids (Kane) as the cellular impact of heavy metals burdens block > > receptor > > sites such as G proteins and ultimately suppress the beta oxidation > > of > > lipids > > and cellular respiration. > > > > Children with autism consistently present with an elevation of > VLCFAs > > However, red cell lipid levels of arachidonic are variable, elevated > > in > > some > > patients while deeply suppressed in others. > > > > Dietary Fat Intervention Must Be Considered > > > > Administration of fish oils suppresses omega 6 and structural lipids > > and this > > will suppress the production of arachidonic acid. To balance fat > > metabolism > > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > > before > > introducing omega 3 lipids. > > > > Patient outcomes may be compromised if one uses fish oils prior to > > omega 6 > > fatty acids. The omega 6 fatty acid of choice would be evening > > primrose > > oil. > > Additionally, supporting the digestion of fats with bile salts and > > lipase is > > frequently required to maximize fat absorption and digestion. > > > > Japan and Mercury Exposure Example > > > > The impact of Hg upon human health was brought to light in the > > mid-50s > > with > > the Minamata disaster in Japan. As noted in the documentary 'Message > > to > > Minamata to the World' the impact of Hg is devastating, most > > prominently to > > the CNS. Interestingly, autistic behavior can observed in the > > documentary of > > Minamata children in original footage after the disaster. > > > > In 1993 Kane found an interesting correlation in the literature > > between > > autism and Hg with the occurrence of autism presenting in adulthood > > occurring > > in Japan. The presentation of autism in these individuals was linked > > to > > ornithine transcarbamylase deficiency, the most common urea cycle > > defect. > > Damage to this enzyme can occur with exposure to mercury. > > > > Low levels of ornithine transcarbamylase (OTC) leads to states of > > hyperammonemia, seizures and stroke. The enzyme OTC controls > ammonia, > > critical issues in states of epilepsy and autism. The often spacy, > > confused > > behavior 'brain fog' that is frequently observed in these disorders > > may > > be > > attributed states of hyperammonemia as ammonia reaches the brain. > > > > Suggested treatment of mildly suppressed levels of OTC includes > > sodium > > benzoate and phenylacetate. However, Kane and other clinicians have > > observed > > positive clinical usefulness of Ca/Mg butyrate, digestive > > intervention > > targeted to biliary flow, appropriate buffers, and stabilization of > > electrolytes and the trace mineral base. > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Well, I didn't make the connection - WHO are you talking about? Re: [ ] Re: DMSA/LA:Another View > Okay, . Got it figured out. I wasn't making the connection. I think > you are 100% right on. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 , I don't think this letter was in anyway an attempt to scare anyone away from detoxing their child. Clearly it seems that some children will stand to benefit, but how that is done is important, and we should strive to have as many opinions as possible, so that somewhere a safe protocol can be delivered. It is funny how some people can crucify someone for using a " pen name " when they themselves do this when they feel the need. Kane Ph.D. was driven away from posting publicly, thanks to others that felt like they had right to do this to another person. If anyone wants to know about Dr.Kane's credentials, well they can e-mail or call AAEM, I will give them the number and address if they would like. There are others on this list, that have already contacted them, and even though they know, still they persist like they don't already know. In the DMSA article it says: Any detoxification regimen requires the bowels to be fully functioning. If a patient is constipated, normal bowel function should be restored prior to DMSA chelation. http://www.thorne.com/altmedrev/.fulltext/5/3/264.html Now my child did not have normal bowel function until we started the Bodybio treatment, but when I tried to talk about this treatment on the lists. I was shot down, and now I don't even want to talk about it any longer. These others drove me away, and that is too bad... too bad for us all. I am fed up with the bashing and slandering, and I was shocked about what was said about Amy, but how do you stop it? Best, Forrest's Mom Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Amen to that... well said!! Maranie Re: [ ] Re: DMSA/LA:Another ViewI was also shot down when I attempted to obtain info on FGF. There becomes a time when I line is crossed with certain individuals who make personal attacks and continue to shove info down our throats. That is why I am investigating this as being counter-productive to the group. I love hearing different opinions but do not wish to be attacked for making them. All kids are different, thats what we have to remember. My fear is that some desperate individual will use some unfounded advice on their child and end up with disasterous results. I like opinions and personal accounts. Medical Advice? That is what I pay my DAN Dr. for: who also is not a big fan of our government and FDA. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Every person is different and all drugs must be used with caution. Any negative reaction cannot be dismissed but understood. We have used both DMSA and DMPS without any problems. The only bad reaction came when we tried the ala with dmsa. WOW! Do not think ALA is just a supplement when if you use it with chelators. It is a drug, one with little to no clinical testing. At least we can read the PDR or Insert for Chemet/DMSA/Captomer for risks and side effects. DMPS has been around for a while and has been tested. It is described as therapy for arsnic tox. by the EPA. I think DMSA may be problematic for some and as such we need to work with a doctor an monitor closely for reactions. Caution and care are the key words. Beverly > > Oh no, not this again!! > > > > Folks, DMPS has not been approved for use in children! And Andy has > > posted quite a lot about the dangers of DMPS. > > > > Hey, even our pediatrician feels VERY comfortable about us using > DMSA > > under our chelating doctor's direction, and the ped. is a VERY > > CONSERVATIVE man. > > > > Some of the statements made below have been taken out of context, > and > > some are just NOT TRUE. > > > > The post below makes DMSA chelation sound very dangerous. In fact, > > DMSA is VERY SAFE. When I asked the doctor who is treating Kenny > > about this " seizure risk " this doctor said that there is absolutely > no > > evidence of this. In point of fact, the risks of using DMPS are > MUCH > > HIGHER. > > > > The post below states: > > > > " Natural medical physicians throughout the US have reported MS > > symptoms in adults and intractable seizures in pediatric patients > with > > high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), > > Chemet or Succimer. " > > > > However, the chelation protocol being used by reputable doctors is > NOT > > a high dose of DMSA. Even aspirin can be dangerous if taken in high > > doses for a long period of time. > > > > Which all points up the fact that BEFORE you do anything with your > > child, make sure you have thoroughly RESEARCHED the approach your > > doctor suggests you take with your child. Ask lots of questions, > and > > make sure your doctor KNOWS what s/he is doing! > > > > (Cary, NC) > > persistentC@b... > > > > [ ] DMSA/LA:Another View > > > > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > > > > > Autism and Mercury Detoxification > > P. Kane, Ph.D. and J. Mercola, D.O. > > > > Recently, it has been proposed that autism may be the aftermath of > > exposure > > to mercury such as ethyl mercury used as a preservative, thimerosal, > > in > > pediatric vaccinations. The article in this newsletter issue reviews > > this > > evidence. > > > > Currently Recommend Pediatric Mercury Protocol > > > > The protocol is always being improved. Drs. Klinghardt, Kane and > > Mercola > > revised this in September 2000 and the most current recommendation > > can > > be > > found by clicking here. Small changes are likely to be regularly > > posted > > but > > we will likely revise the protocol in December when we all are > > presenters at > > the Healing Your Brain 2000 Seminar. > > > > We currently are planning hold a one day workshop at the American > > Academy of > > Environmental Medicine to invite some of the top clinicians in > > mercury > > detoxification to further improve the program. Additionally, Wayne > > Obie, of > > TalkInternational.com is planning on facilitating an international > > collaboration on a revised mercury detoxification program. > > > > What is DMSA and Why Don't We Recommend It? > > > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > > which > > each > > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > forming > > water soluble chelates which increases the urinary excretion of > lead. > > > > There are a number of physicians who have started to use DMSA to > > remove > > the > > mercury from children with autism. The dose used for mercury > > detoxification > > is much lower than that for lead and many children seem to have > > received > > benefit from this approach. > > > > A time released DMSA is being used for 7 days on, 7 days off or 3 > > days > > on, 4 > > days off for an extended period of time (up to 6 months). > > > > However, some natural medicine clinicians have some serious concerns > > about > > the use of DMSA. There have been cases of: > > > > > > seizures > > > > increased self-stimming > > > > and compromised central nervous system function in some children. > > > > > > DMSA and Mercury Redistribution To The Brain > > > > It appears that DMSA and lipoic acid can create tissue > redistribution > > of > > mercury as decreasing Hg levels in the kidney (the organ > accumulating > > Hg most > > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > heart, > > muscle and liver (Gregus et al). > > > > Natural medical physicians throughout the US have reported MS > > symptoms > > in > > adults and intractable seizures in pediatric patients with high dose > > and > > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > > Succimer. > > > > Other Problems With DMSA > > > > Extended use of DMSA can cause mild to moderate neutropenia with > > increased > > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > > Blood > > Urea > > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > > convulsions, > > rash, > > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > > neuropathy, > > decreased urination, arrhythmia, infection. Zinc excretion doubles > > during the > > administration of DMSA. Patients must be kept hydrated as renal > > function can > > be compromised. > > > > For the above described reasons in all good conscious we can not > > recommend > > the use of DMSA for the treatment of mercury toxic pediatric > patients. > > > > Approaching the fragile brain architecture of young children with > > autism, PDD > > and seizure disorders brings about tremendous responsibility in > > protecting > > the children from invasive interventions that risk alteration in > > brain > > function. > > > > Hair Analysis For Diagnosis and Treatment > > > > First, a determination must be made if, in fact, there is a heavy > > metal > > burden and if so specifically which heavy metals are involved such > as > > aluminum, mercury, lead or others. > > > > This is the reason why hair analysis is a recommended initial > screen. > > At this > > time we only advise two labs for this determination. Trace Elements > > in > > Austin, Texas and Analytical Research in Arizona. > > > > Both of these labs do not wash the hair samples prior to analysis. > > This > > is a > > key factor to proper interpretation of the other nontoxic minerals. > > > > Other labs would likely give proper heavy metal results, but the > > interpretation of the other minerals is key to an effective > > supplementation > > program. Chelation removes other minerals aside from mercury and > > these > > must > > be replaced properly if one wished to avoid complications. > > > > Establishing Metabolic Stability Prior To Detoxification > > > > One must be relatively healthy to sustain the process of > > detoxification. Once > > metabolic stability is established physicians often find that gentle > > biological interventions clear heavy metal burdens without the need > > for > > medication that holds the potential risk of negative side effects or > > merely > > redistribution of heavy metals. > > > > Clearing heavy metals may be approached by first reestablishing the > > mineral > > base, supporting biliary function/ digestion, insuring the patient > is > > properly hydrated (children with autism are frequently dehydrated), > > and > > most > > importantly supporting hepatic function and metabolism > > > > Adults with heavy metal toxicity generally have significant > > suppression > > of > > omega 6 arachidonic acid and a significant elevation of very long > > chain > > fatty > > acids (Kane) as the cellular impact of heavy metals burdens block > > receptor > > sites such as G proteins and ultimately suppress the beta oxidation > > of > > lipids > > and cellular respiration. > > > > Children with autism consistently present with an elevation of > VLCFAs > > However, red cell lipid levels of arachidonic are variable, elevated > > in > > some > > patients while deeply suppressed in others. > > > > Dietary Fat Intervention Must Be Considered > > > > Administration of fish oils suppresses omega 6 and structural lipids > > and this > > will suppress the production of arachidonic acid. To balance fat > > metabolism > > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > > before > > introducing omega 3 lipids. > > > > Patient outcomes may be compromised if one uses fish oils prior to > > omega 6 > > fatty acids. The omega 6 fatty acid of choice would be evening > > primrose > > oil. > > Additionally, supporting the digestion of fats with bile salts and > > lipase is > > frequently required to maximize fat absorption and digestion. > > > > Japan and Mercury Exposure Example > > > > The impact of Hg upon human health was brought to light in the > > mid-50s > > with > > the Minamata disaster in Japan. As noted in the documentary 'Message > > to > > Minamata to the World' the impact of Hg is devastating, most > > prominently to > > the CNS. Interestingly, autistic behavior can observed in the > > documentary of > > Minamata children in original footage after the disaster. > > > > In 1993 Kane found an interesting correlation in the literature > > between > > autism and Hg with the occurrence of autism presenting in adulthood > > occurring > > in Japan. The presentation of autism in these individuals was linked > > to > > ornithine transcarbamylase deficiency, the most common urea cycle > > defect. > > Damage to this enzyme can occur with exposure to mercury. > > > > Low levels of ornithine transcarbamylase (OTC) leads to states of > > hyperammonemia, seizures and stroke. The enzyme OTC controls > ammonia, > > critical issues in states of epilepsy and autism. The often spacy, > > confused > > behavior 'brain fog' that is frequently observed in these disorders > > may > > be > > attributed states of hyperammonemia as ammonia reaches the brain. > > > > Suggested treatment of mildly suppressed levels of OTC includes > > sodium > > benzoate and phenylacetate. However, Kane and other clinicians have > > observed > > positive clinical usefulness of Ca/Mg butyrate, digestive > > intervention > > targeted to biliary flow, appropriate buffers, and stabilization of > > electrolytes and the trace mineral base. > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Chelation of children for low levels of toxicity is not an approved form of treatment. It isn't widely known and there are no ultimate experts and there is no one protocal that is right for every kid or for that matter autistic kids. We can only hope to find a Dr on " the path " or interested in learning and trying things we have to research out. Sort of a health care partnership. Some may chose to wait until some studies are done which no doubt will not be conclusive any way. I believe in trying things that are reasonably safe. Chelation is one of those things I researched and tried with great results. We are not done but I cannot wait for the world to catch up. This kid chelating for autism is cutting edge and there will be alot of different approaches. No one is THE expert yet. Do what works and do not do any thing that is harming in any way. It is an awesome task, but that is a parents job. Beverly > > > Which all points up the fact that BEFORE you do anything with your > > > child, make sure you have thoroughly RESEARCHED the approach your > > > doctor suggests you take with your child. Ask lots of questions, > > and > > > make sure your doctor KNOWS what s/he is doing! > > > > > > (Cary, NC) > > > persistentC@b... > > > > > > [ ] DMSA/LA:Another View > > > > > > > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > > > > > > > > > Autism and Mercury Detoxification > > > P. Kane, Ph.D. and J. Mercola, D.O. > > > > > > Recently, it has been proposed that autism may be the aftermath of > > > exposure > > > to mercury such as ethyl mercury used as a preservative, thimerosal, > > > in > > > pediatric vaccinations. The article in this newsletter issue reviews > > > this > > > evidence. > > > > > > Currently Recommend Pediatric Mercury Protocol > > > > > > The protocol is always being improved. Drs. Klinghardt, Kane and > > > Mercola > > > revised this in September 2000 and the most current recommendation > > > can > > > be > > > found by clicking here. Small changes are likely to be regularly > > > posted > > > but > > > we will likely revise the protocol in December when we all are > > > presenters at > > > the Healing Your Brain 2000 Seminar. > > > > > > We currently are planning hold a one day workshop at the American > > > Academy of > > > Environmental Medicine to invite some of the top clinicians in > > > mercury > > > detoxification to further improve the program. Additionally, Wayne > > > Obie, of > > > TalkInternational.com is planning on facilitating an international > > > collaboration on a revised mercury detoxification program. > > > > > > What is DMSA and Why Don't We Recommend It? > > > > > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > > > which > > > each > > > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > > forming > > > water soluble chelates which increases the urinary excretion of > > lead. > > > > > > There are a number of physicians who have started to use DMSA to > > > remove > > > the > > > mercury from children with autism. The dose used for mercury > > > detoxification > > > is much lower than that for lead and many children seem to have > > > received > > > benefit from this approach. > > > > > > A time released DMSA is being used for 7 days on, 7 days off or 3 > > > days > > > on, 4 > > > days off for an extended period of time (up to 6 months). > > > > > > However, some natural medicine clinicians have some serious concerns > > > about > > > the use of DMSA. There have been cases of: > > > > > > > > > seizures > > > > > > increased self-stimming > > > > > > and compromised central nervous system function in some children. > > > > > > > > > DMSA and Mercury Redistribution To The Brain > > > > > > It appears that DMSA and lipoic acid can create tissue > > redistribution > > > of > > > mercury as decreasing Hg levels in the kidney (the organ > > accumulating > > > Hg most > > > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > > heart, > > > muscle and liver (Gregus et al). > > > > > > Natural medical physicians throughout the US have reported MS > > > symptoms > > > in > > > adults and intractable seizures in pediatric patients with high dose > > > and > > > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > > > Succimer. > > > > > > Other Problems With DMSA > > > > > > Extended use of DMSA can cause mild to moderate neutropenia with > > > increased > > > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > > > Blood > > > Urea > > > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > > > convulsions, > > > rash, > > > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > > > neuropathy, > > > decreased urination, arrhythmia, infection. Zinc excretion doubles > > > during the > > > administration of DMSA. Patients must be kept hydrated as renal > > > function can > > > be compromised. > > > > > > For the above described reasons in all good conscious we can not > > > recommend > > > the use of DMSA for the treatment of mercury toxic pediatric > > patients. > > > > > > Approaching the fragile brain architecture of young children with > > > autism, PDD > > > and seizure disorders brings about tremendous responsibility in > > > protecting > > > the children from invasive interventions that risk alteration in > > > brain > > > function. > > > > > > Hair Analysis For Diagnosis and Treatment > > > > > > First, a determination must be made if, in fact, there is a heavy > > > metal > > > burden and if so specifically which heavy metals are involved such > > as > > > aluminum, mercury, lead or others. > > > > > > This is the reason why hair analysis is a recommended initial > > screen. > > > At this > > > time we only advise two labs for this determination. Trace Elements > > > in > > > Austin, Texas and Analytical Research in Arizona. > > > > > > Both of these labs do not wash the hair samples prior to analysis. > > > This > > > is a > > > key factor to proper interpretation of the other nontoxic minerals. > > > > > > Other labs would likely give proper heavy metal results, but the > > > interpretation of the other minerals is key to an effective > > > supplementation > > > program. Chelation removes other minerals aside from mercury and > > > these > > > must > > > be replaced properly if one wished to avoid complications. > > > > > > Establishing Metabolic Stability Prior To Detoxification > > > > > > One must be relatively healthy to sustain the process of > > > detoxification. Once > > > metabolic stability is established physicians often find that gentle > > > biological interventions clear heavy metal burdens without the need > > > for > > > medication that holds the potential risk of negative side effects or > > > merely > > > redistribution of heavy metals. > > > > > > Clearing heavy metals may be approached by first reestablishing the > > > mineral > > > base, supporting biliary function/ digestion, insuring the patient > > is > > > properly hydrated (children with autism are frequently dehydrated), > > > and > > > most > > > importantly supporting hepatic function and metabolism > > > > > > Adults with heavy metal toxicity generally have significant > > > suppression > > > of > > > omega 6 arachidonic acid and a significant elevation of very long > > > chain > > > fatty > > > acids (Kane) as the cellular impact of heavy metals burdens block > > > receptor > > > sites such as G proteins and ultimately suppress the beta oxidation > > > of > > > lipids > > > and cellular respiration. > > > > > > Children with autism consistently present with an elevation of > > VLCFAs > > > However, red cell lipid levels of arachidonic are variable, elevated > > > in > > > some > > > patients while deeply suppressed in others. > > > > > > Dietary Fat Intervention Must Be Considered > > > > > > Administration of fish oils suppresses omega 6 and structural lipids > > > and this > > > will suppress the production of arachidonic acid. To balance fat > > > metabolism > > > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > > > before > > > introducing omega 3 lipids. > > > > > > Patient outcomes may be compromised if one uses fish oils prior to > > > omega 6 > > > fatty acids. The omega 6 fatty acid of choice would be evening > > > primrose > > > oil. > > > Additionally, supporting the digestion of fats with bile salts and > > > lipase is > > > frequently required to maximize fat absorption and digestion. > > > > > > Japan and Mercury Exposure Example > > > > > > The impact of Hg upon human health was brought to light in the > > > mid-50s > > > with > > > the Minamata disaster in Japan. As noted in the documentary 'Message > > > to > > > Minamata to the World' the impact of Hg is devastating, most > > > prominently to > > > the CNS. Interestingly, autistic behavior can observed in the > > > documentary of > > > Minamata children in original footage after the disaster. > > > > > > In 1993 Kane found an interesting correlation in the literature > > > between > > > autism and Hg with the occurrence of autism presenting in adulthood > > > occurring > > > in Japan. The presentation of autism in these individuals was linked > > > to > > > ornithine transcarbamylase deficiency, the most common urea cycle > > > defect. > > > Damage to this enzyme can occur with exposure to mercury. > > > > > > Low levels of ornithine transcarbamylase (OTC) leads to states of > > > hyperammonemia, seizures and stroke. The enzyme OTC controls > > ammonia, > > > critical issues in states of epilepsy and autism. The often spacy, > > > confused > > > behavior 'brain fog' that is frequently observed in these disorders > > > may > > > be > > > attributed states of hyperammonemia as ammonia reaches the brain. > > > > > > Suggested treatment of mildly suppressed levels of OTC includes > > > sodium > > > benzoate and phenylacetate. However, Kane and other clinicians have > > > observed > > > positive clinical usefulness of Ca/Mg butyrate, digestive > > > intervention > > > targeted to biliary flow, appropriate buffers, and stabilization of > > > electrolytes and the trace mineral base. > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 I think we need to " let it all air out " . I want to read everything. Even if I do not agree or someone else disagrees, it is important to keep the dialoge open. It is clear that some people are crusaders or may be selling something, others looking for an audience and yet others sharing experiences and seeking information. I lost thin skin some where along the way. I too got severly bashed a few times too and know some over reacted to a post or two, and I almost picked up my marbles and left. I am glad I didn't. I did not read anything that offensive in this last mini war of sorts. You may disagree, but I feel like I am missing out on sharing experiences, some dirty on line gossip, when there are posts filled with half messages, insiders only can figure out. Well if you must chatter, than chatter, but I hope no one feels unwanted or intimidated into returning to lurking. We need to evaluate everyones research and experiences. Beverly > Let's let civil discussion be just that. I remember articles from Dr. > Holmes considering DMPS for her son in late March 2000. Obviously she > found DMSA was a better route. Even that, she has modified > (in days on and off). I also heard Dr. Holmes state at the DAN > that she has used FGF for her son, also. She even did CLO and > still, during chelation, I believe she said she does occasional > Bethanacol , 5 mg. I WANT to hear people's experiences. > It helps me identify if my son is in a certain category of > responders...and to what. Aly > > Re: [ ] Re: DMSA/LA:Another View > > > I was also shot down when I attempted to obtain info on FGF. There becomes > a > time when I line is crossed with certain individuals who make personal > attacks and continue to shove info down our throats. That is why I am > investigating this as being counter-productive to the group. I love hearing > different opinions but do not wish to be attacked for making them. All kids > are different, thats what we have to remember. My fear is that some > desperate individual will use some unfounded advice on their child and end > up > with disasterous results. I like opinions and personal accounts. Medical > Advice? That is what I pay my DAN Dr. for: who also is not a big fan of our > government and FDA. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 I feel the same way, . I don't even know the type of doctor I'm looking for.....I have seen the words " enviornmental doctors " used by Kirkman's president and I have also seen the category: Neurotoxicologist used on internet web sites. I called Kaiser my HMO, and asked health services if they had a doctor in such a category .....well, that was a waste of time. I now am awaiting a call from my son's Kaiser neurologist in regards to his recent urine and blood tests. I hate to sound pessimistic, but they'll be normal and I'll have a patient discussion with them about Mercury's action in the body. With Secretin, the gastroenterologist said: I refuse to even discuss it with you. I may be accomplished in my area of expertise, but over there, I believe they think I'm really stupid. Aly Re: [ ] Re: DMSA/LA:Another View I don't know if there IS such a thing as the perfect doctor for us and our children. I'm talking with three doctors about this right now - an M.D., a D.O., and a psychiatrist and what do I look for? Someone who will go along with me. We parents look into these issues SO much more extensively than the doctors - they have tunnel vision. We look at ALL the possibilities with an open mind. [ ] DMSA/LA:Another View > > > > > > Taken from: http://www.mercola.com/2000/oct/1/mercury_autism.htm > > > > > > > > Autism and Mercury Detoxification > > P. Kane, Ph.D. and J. Mercola, D.O. > > > > Recently, it has been proposed that autism may be the aftermath of > > exposure > > to mercury such as ethyl mercury used as a preservative, thimerosal, > > in > > pediatric vaccinations. The article in this newsletter issue reviews > > this > > evidence. > > > > Currently Recommend Pediatric Mercury Protocol > > > > The protocol is always being improved. Drs. Klinghardt, Kane and > > Mercola > > revised this in September 2000 and the most current recommendation > > can > > be > > found by clicking here. Small changes are likely to be regularly > > posted > > but > > we will likely revise the protocol in December when we all are > > presenters at > > the Healing Your Brain 2000 Seminar. > > > > We currently are planning hold a one day workshop at the American > > Academy of > > Environmental Medicine to invite some of the top clinicians in > > mercury > > detoxification to further improve the program. Additionally, Wayne > > Obie, of > > TalkInternational.com is planning on facilitating an international > > collaboration on a revised mercury detoxification program. > > > > What is DMSA and Why Don't We Recommend It? > > > > DMSA is a FDA currently approved drug. It is a mixed disulfide in > > which > > each > > of the sulfur atoms is in disulfide linkage with a cysteine molecule > > forming > > water soluble chelates which increases the urinary excretion of > lead. > > > > There are a number of physicians who have started to use DMSA to > > remove > > the > > mercury from children with autism. The dose used for mercury > > detoxification > > is much lower than that for lead and many children seem to have > > received > > benefit from this approach. > > > > A time released DMSA is being used for 7 days on, 7 days off or 3 > > days > > on, 4 > > days off for an extended period of time (up to 6 months). > > > > However, some natural medicine clinicians have some serious concerns > > about > > the use of DMSA. There have been cases of: > > > > > > seizures > > > > increased self-stimming > > > > and compromised central nervous system function in some children. > > > > > > DMSA and Mercury Redistribution To The Brain > > > > It appears that DMSA and lipoic acid can create tissue > redistribution > > of > > mercury as decreasing Hg levels in the kidney (the organ > accumulating > > Hg most > > abundantly) increases Hg concentrations of Hg in blood, brain, lung, > > heart, > > muscle and liver (Gregus et al). > > > > Natural medical physicians throughout the US have reported MS > > symptoms > > in > > adults and intractable seizures in pediatric patients with high dose > > and > > extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or > > Succimer. > > > > Other Problems With DMSA > > > > Extended use of DMSA can cause mild to moderate neutropenia with > > increased > > SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and > > Blood > > Urea > > Nitrogen (BUN). Adverse reactions to DMSA include ataxia, > > convulsions, > > rash, > > nausea, diarrhea, anorexia, headache, dizziness, sensorimotor > > neuropathy, > > decreased urination, arrhythmia, infection. Zinc excretion doubles > > during the > > administration of DMSA. Patients must be kept hydrated as renal > > function can > > be compromised. > > > > For the above described reasons in all good conscious we can not > > recommend > > the use of DMSA for the treatment of mercury toxic pediatric > patients. > > > > Approaching the fragile brain architecture of young children with > > autism, PDD > > and seizure disorders brings about tremendous responsibility in > > protecting > > the children from invasive interventions that risk alteration in > > brain > > function. > > > > Hair Analysis For Diagnosis and Treatment > > > > First, a determination must be made if, in fact, there is a heavy > > metal > > burden and if so specifically which heavy metals are involved such > as > > aluminum, mercury, lead or others. > > > > This is the reason why hair analysis is a recommended initial > screen. > > At this > > time we only advise two labs for this determination. Trace Elements > > in > > Austin, Texas and Analytical Research in Arizona. > > > > Both of these labs do not wash the hair samples prior to analysis. > > This > > is a > > key factor to proper interpretation of the other nontoxic minerals. > > > > Other labs would likely give proper heavy metal results, but the > > interpretation of the other minerals is key to an effective > > supplementation > > program. Chelation removes other minerals aside from mercury and > > these > > must > > be replaced properly if one wished to avoid complications. > > > > Establishing Metabolic Stability Prior To Detoxification > > > > One must be relatively healthy to sustain the process of > > detoxification. Once > > metabolic stability is established physicians often find that gentle > > biological interventions clear heavy metal burdens without the need > > for > > medication that holds the potential risk of negative side effects or > > merely > > redistribution of heavy metals. > > > > Clearing heavy metals may be approached by first reestablishing the > > mineral > > base, supporting biliary function/ digestion, insuring the patient > is > > properly hydrated (children with autism are frequently dehydrated), > > and > > most > > importantly supporting hepatic function and metabolism > > > > Adults with heavy metal toxicity generally have significant > > suppression > > of > > omega 6 arachidonic acid and a significant elevation of very long > > chain > > fatty > > acids (Kane) as the cellular impact of heavy metals burdens block > > receptor > > sites such as G proteins and ultimately suppress the beta oxidation > > of > > lipids > > and cellular respiration. > > > > Children with autism consistently present with an elevation of > VLCFAs > > However, red cell lipid levels of arachidonic are variable, elevated > > in > > some > > patients while deeply suppressed in others. > > > > Dietary Fat Intervention Must Be Considered > > > > Administration of fish oils suppresses omega 6 and structural lipids > > and this > > will suppress the production of arachidonic acid. To balance fat > > metabolism > > it is crucial to stabilize omega 6 fatty acids and arachidonic acid > > before > > introducing omega 3 lipids. > > > > Patient outcomes may be compromised if one uses fish oils prior to > > omega 6 > > fatty acids. The omega 6 fatty acid of choice would be evening > > primrose > > oil. > > Additionally, supporting the digestion of fats with bile salts and > > lipase is > > frequently required to maximize fat absorption and digestion. > > > > Japan and Mercury Exposure Example > > > > The impact of Hg upon human health was brought to light in the > > mid-50s > > with > > the Minamata disaster in Japan. As noted in the documentary 'Message > > to > > Minamata to the World' the impact of Hg is devastating, most > > prominently to > > the CNS. Interestingly, autistic behavior can observed in the > > documentary of > > Minamata children in original footage after the disaster. > > > > In 1993 Kane found an interesting correlation in the literature > > between > > autism and Hg with the occurrence of autism presenting in adulthood > > occurring > > in Japan. The presentation of autism in these individuals was linked > > to > > ornithine transcarbamylase deficiency, the most common urea cycle > > defect. > > Damage to this enzyme can occur with exposure to mercury. > > > > Low levels of ornithine transcarbamylase (OTC) leads to states of > > hyperammonemia, seizures and stroke. The enzyme OTC controls > ammonia, > > critical issues in states of epilepsy and autism. The often spacy, > > confused > > behavior 'brain fog' that is frequently observed in these disorders > > may > > be > > attributed states of hyperammonemia as ammonia reaches the brain. > > > > Suggested treatment of mildly suppressed levels of OTC includes > > sodium > > benzoate and phenylacetate. However, Kane and other clinicians have > > observed > > positive clinical usefulness of Ca/Mg butyrate, digestive > > intervention > > targeted to biliary flow, appropriate buffers, and stabilization of > > electrolytes and the trace mineral base. > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2000 Report Share Posted October 2, 2000 Let's let civil discussion be just that. I remember articles from Dr. Holmes considering DMPS for her son in late March 2000. Obviously she found DMSA was a better route. Even that, she has modified (in days on and off). I also heard Dr. Holmes state at the DAN that she has used FGF for her son, also. She even did CLO and still, during chelation, I believe she said she does occasional Bethanacol , 5 mg. I WANT to hear people's experiences. It helps me identify if my son is in a certain category of responders...and to what. Aly Re: [ ] Re: DMSA/LA:Another View I was also shot down when I attempted to obtain info on FGF. There becomes a time when I line is crossed with certain individuals who make personal attacks and continue to shove info down our throats. That is why I am investigating this as being counter-productive to the group. I love hearing different opinions but do not wish to be attacked for making them. All kids are different, thats what we have to remember. My fear is that some desperate individual will use some unfounded advice on their child and end up with disasterous results. I like opinions and personal accounts. Medical Advice? That is what I pay my DAN Dr. for: who also is not a big fan of our government and FDA. Quote Link to comment Share on other sites More sharing options...
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