Fw: [] Phosphytidyl Choline

[Guest guest]

This is a forward and is worth reading, tho it sounds disjointed in the

beginning. Sorry I have no link for the original source.

Donna

http://www.excellentthings.com

<<I don't know the fellow who wrote this or anything about him. I do know that

our Illinois Dr. B. is using this protocol--

IV phosphytidyl choline with glutathione.

Also has oral PhosChol with Cat's claw and Ox bile protocol supplements.

Jeanette

I promised some more information and yet I have been looking at this cursed

computer screen from across the room for two days now. Many have seen my

name on these message boards for nearly two years now. Many also are aware

of the intensity with which I searched and learned. For over a year at 16-18

hours per day and then most of one more year at 8-12 hours even while

working. First learning all I could of borrelia and then the other

spirochetes and then broadening into all of the other neurodegenerative

diseases. Then the search was refined into building a mental map of the

neuroimmune cascade that has gone askew. This coupled with my experiments,

led down into the cytokines. led the way further into MMP-9. I was

able to manipulate each, sometimes only crudely, but still enough to see

that it was a dead end. How many months ago did I post that we have to start

looking beyond the cytokines? I did this. Desperately searching for the holy

grail, a place in the immune system where the cascade is initiated. Hoping

to slow or maybe even stop the degeneration and wasting of the body and

mind. I never hoped for more then this thou. Sitting at the meetings and

also seeing on the boards that each and every treatment helped but did not

stop it. I have seen many die, some by thier own hands and I have seen

others driven into madness, leaving all reason behind. One of those is a

very dear friend who was a mentor in the science and who also I shared

moments of private levity with. I still desperately hope that that friend

finds the way back out. I myself have been locked into some of these places

of utter darkness and I was terrified; terrified that one day I would not

escape. We have all seen that one of the possible outcomes is schizophrenia

and this always weighed on my mind. I made a pact with myself that if it was

getting too bad that I would leave to die with some dignity instead of

draining every last penny from my wife and child, who would end up with just

an empty shell of a father anyway. Others have stated the same to me. So

again, the most that I had ever hoped for was a slowing or a halt. Reversal

of the neural damage never crossed my mind, I never dared dream of such a

possibilty.

The impossible has happened thou and yet I find myself so greedy for the

life that is rapidly returning to me that I find it difficult to spend even

five minutes here at this computer. A tool which saved my life but removed

me from my daughter and wife. There were no longer any friends, except in

some vast worldwide, etheral flow of electrons. So for one last time I will

spend all night on this computer fullfilling a promise. I have always said

that if I found an answer that I would write detailed instructions, post it

widely and then leave to return to the world of the living.

This fullfills that contract,

Whitehead

So many experiments, the first by accident and it was just an undeniable

hunger for stupid ginger snap cookies. Over time the experiments were

refined and simple chemicals were used, some were helpful, some did nothing

and some caused harm. Actaully the harmful ones were the ones that I learned

the most from. Arginine was extremely painful and induced demyelination and

I lost a nerve in only six hours. But it showed me the involvement of iNOs

and peroxynitrite. This led to the work that showed that dextromethorphan

would be helpful as an NMDA receptor antagonist and it was, at times

remarkably so. At other times it still didn't stop the damage from other

chemical pathways. It also showed that I needed to go up in the immune

system, instead of down to TNF, IL-6 etc. This eventually led to leptin,

ghrelin and orexin A & B. These are the adipose hormones and they control

simply everything; energy regulation, metabolism, immunity, insulin/glucose

and the HPA axis (hypothalamus, pituitary and adrenal glands).

I searched and found how to control leptin with vitamin D and a simple

cation; zinc. They worked wonderfully and the experiments clearly showed the

different cycles we go through on a daily, monthly and annual basis.

Unfortunately there was one abstract that was published too late showing

that zinc downregulates calprotectin and calprotectin is the one part of the

immune system that keeps borrelia in check:

Infect Immun. 2003 Aug;71(8):4711-6.

Calprotectin, an abundant cytosolic protein from human polymorphonuclear

leukocytes, inhibits the growth of Borrelia burgdorferi.

Lusitani D, Malawista SE, Montgomery RR.

Department of Internal Medicine, Yale University School of Medicine, New

Haven, Connecticut 06520, USA.

We previously showed that numerous polymorphonuclear leukocyte (PMN) granule

components efficiently kill Borrelia burgdorferi, the agent of Lyme disease.

In addition, motile, granule-poor cytoplasts (U-Cyt) from human blood PMN

can exert anti-Borrelia activity against opsonized B. burgdorferi

independently of oxidative mechanisms. Here we show that lysates of U-Cyt

also possess anti-Borrelia activity, a portion of which comes from the

abundant cytosolic protein calprotectin. The anti-Borrelia activity of U-Cyt

lysates and recombinant calprotectin was partially or completely reversed by

specific antibody to calprotectin and by Zn(2+), a cation essential for the

growth of B. burgdorferi and known to inhibit the antimicrobial activity of

calprotectin. Quantitative microscopic and regrowth assays revealed that

calprotectin acted in a bacteriostatic fashion against B. burgdorferi. We

conclude that calprotectin, a potent bacteriostatic agent from a cell

primarily recognized for its oxidative and granular antibacterial

mechanisms, may play a modulatory role in infection by the Lyme spirochete,

particularly at sites of acute inflammation.

As I pointed out, this abstract came out too late. I had already been using

zinc for a month and the encephalitis had just started when I read this. The

encephalitis lasted for a month and nearly took my life at least 3 times. On

those occasions I had to send my wife and daughter to her sisters house. I

did not want anyone to see me or how bad it got and I also didn't want any

pointless, fruitless intervention if the worst came. This finally ended but

I immediately went into encephalopathy with full blown dementia and this

lasted for over a week. I will always thank god for these five weeks. It was

during this period that I realised that leptin and it's friends still

weren't what I was searching for. I then knew that it was in the adipose

tissue itself. Adipose tissue contains lipids which are also known as fats

or fatty acids. Within 2 days of coming to this conclusion, Nellie posted a

paper by Patrica Kane PhD on Eurolyme. It is available @:

http://www.mercola.com/2003/aug/9/detoxification_biotoxins.htm

I knew immediately upon seeing this that it was what I had been looking for,

for so long, yet there was never even one comment ever posted in reply to

it. No one else understood it's significance. I told my wife when I read it

that if there was just one thing I could do in this life it would be to do

this protocol. During the encephalitis, my wife had very little to do with

me and never noticed how bad I was. When the encephalopathy with dementia

hit, even my daughter noticed that something was seriously wrong. There was

only one thing anybody could see if they really, really looked into my eyes

at this point and that was death.

On Friday, Sept. 26 I woke my wife up at 7AM and MADE her look at me and in

my eyes. She did finally see and it scared the sh*t out of her. I told her

that I was going to have to call my dad or someone but that I needed the

money to go up to see Dr. Kane now. She gave me her credit card. I called

Dr. Kane's office and explained to the receptionist who I was and the

research I had been doing and that I needed to get in to start treatment on

an emergency basis. I also mentioned the name of a mutual friend that Dr.

Kane knew that could vouch for what I had been doing. They let me come up on

Tuesday. I spent an hour with a Dr. Bracchia MD who authorised the treatment

and within 10 minutes of receiving the first phospatidyl choline and

glutahione IVs my head was crystal clear. Two hours I spent in the IV lounge

and was just blown away, CFS, MS, FMS & lymie patients and everyone was

doing great. In fact everyone looked not just good but healthy. While I was

there I saw my very first ALS case. It was a woman and her first visit, she

was just a rigid zombie and could no longer speak. Her husband said that

they had tried everything and nothing had worked but that they finally met

two people that had been through the treatments, one had been recovered for

6 months and the other a year. I then went in and spent two hours talking

with . She was the first person, including doctors that I had ever

met that knew all of the interactions of the chemical pathways like I did.

She was even able to fill in a couple of blanks.

I started the high fat, high protein and low carb diet, oils and liquid

phosphatidyl choline that day. On the third day some of the previous

symptoms did return but each day after that there was more and more

progress. This last Wednesday I went back for more IV's and met Joe. Joe has

ALS/lyme and had lost the use of everything below his neck. He had been to

32 doctors and nothing helped. When he first arrived he had already started

gasping for air at times which means his diaphram was starting to be

paralysed. He had very little time left in this world. He showed me how he

could raise his arms over his head and his hand/claws were starting to

straighten. His face was no longer a rigid mask and he delighted in sticking

his tongue out at people because HE COULD! The following day he was able to

use his feet to raised and lower the wheelchair footrests and he had perfect

control over his feet. Joe had only been in treatment for 3 weeks.

This last Wednesday night I came back and wrote the Joe message and posted

it. While I was sitting at the computer I all of a suddent just knew, not

felt, BUT KNEW that I was going to be alright. All of the way back to normal

including, barring an accident, seeing my 7 yr old daughter turn into a lady

one day. All of this is being done without targeting any kind of infectious

organism, no ABx or AVx and the very worst neurological cases are

recovering. Dr. Perlmutter is one of the top neurologists in the world. He

is the one that other neurologists send their difficult cases to. Dr.

Perlmutter is now sending people to the Haverford clinic and he is adopting

's protocol.

It does greatly speed up the recovery if you do the PhosChol and Glutathione

IVs but you will still recover doing just the oral PhosChol. In this way

everything can be done under the medical review radar like in England and

everything could be purchased on the internet.

The easiest thing to do would be to go to:

http://www.detoxxbook.com/main/products/sdetoxxbook.htm

Get the Physicians book which costs $29.95

This one shows how you could do it at home and also explains the science

behind it. It is phospholipid exchange and detoxification. The detox is

important because it stops more damage but the phospholipid exchange

rebuilds the membrane and restores homeostasis and all of the functions

including normal immunity and normal neurotransmitter levels. It actually

rebuilds each and every cell in your body.

Here is one clue of just part of what is happens:

Extracellular phospholipase A2 inhibitors suppress central nervous

system inflammation

Florence Pinto 1, Talma Brenner 1 *, Phyllis Dan 2, Miron Krimsky 2,

Saul Yedgar 2

1Laboratory of Neuroimmunology, Department of Neurology, Hadassah

University Hospital and Hebrew University Medical School, Jerusalem, Israel

2Department of Biochemistry, Hebrew University-Hadassah Medical

School, Jerusalem, Israel

email: Talma Brenner (brenner@...)

*Correspondence to Talma Brenner, Laboratory of Neuroimmunology, Department

of Neurology, Hadassah University Hospital, P.O. Box 12000, Jerusalem 91120,

Israel

Funded by:

Israel Ministry of Health's Chief-Scientist fund

Hilda Katz Blaustein Fund

Keywords

experimental autoimmune encephalomyelitis . glial cells .

membrane-anchored PLA2 inhibitors . nitric oxide . PGE2

Abstract

Phospholipase A2 (PLA2) plays a key role in the production of

proinflammatory mediators, namely the arachidonic acid-derived eicosanoids,

lysophospholipids, and platelet-activating factor, and indirectly influences

the generation of cytokines, nitric oxide (NO), and free radicals.

Accordingly, regulation of its activity is important in the treatment of

inflammation. Since the main site of PLA2 action in inflammatory processes

is the cell membrane, we synthesized extracellular PLA2 inhibitors (ExPLIs)

composed of N-derivatized phosphatidyl-ethanolamine linked to polymeric

carriers. These membrane-anchored lipid conjugates do not penetrate the cell

and interfere with vital phospholipid metabolism or cell viability. The

ExPLIs markedly inhibited central nervous system inflammation. This was

reflected by the suppressed production and secretion of

lipopolysaccharide-induced sPLA2, prostaglandin E2, and NO by glial cells

and by the amelioration of experimental autoimmune encephalomyelitis in rats

and mice. © 2003 Wiley-Liss, Inc.

But again, that is just what happens if you inhibit the PLA2. WIth what I am

doing though you are completely rebuilding the membrane and this eliminates

this problem and much more.

I am posting this to Spinlyme, Eurolyme, Neuroborreliosis and LymeAid. It

will probably provoke a huge amount of discussion on some sites and fights

in other. Everybody fights about the least little thing anymore but I don't

really give a damn. There are enough on each site that do know my work and

they will be interested. This is all it is going to take. A few will do it

and then they will tell others and they will try it. " Build it and they will

come "

I have done what I set out to do and now I am going to start learning about

my daughter. I had just formed the group Neuroborreliosis. I will keep it up

for a couple more weeks but won't be on there. If anyone want's ownership of

it then let me know. I won't be at the November meeting of NatCapLyme but

will at the December meeting. By this time no one will be able to refute

what they see when I walk throguh the door. Both my wife and Kaye have

already seen that I am growing younger looking. All anyone will really have

to do to know for sure is come up and look into my eyes. That will be my

last meeting and I will resign from the board there.

For those interested in starting the formal protocol you can call 888 320

8338 to get the phone numbers for:

Haverford Wellness Center in Haverford, PA or The Center for Wellness in

Charlotte, NC

Unfortunately at Haverford, an appointment with Dr. Kane is virtually

impossible now. She simply has no time anymore except for seeing the gravely

ill cases such as ALS that are coming in. But Dr. Bracchia initiates the

treatment anyway. But no matter who, all cases are still reviewed and

monitored by Dr. Kane.

I know that Dr. Perlmutter is just starting to do it in Naples, FL but there

is no telling how expensive it is going to be there.

Outside Munich, Germany there is a husband and wife team that are also doing

the phospholipid exchange; Dr. Meinrad Milz & Dr. Katrin Bieber. It

shouldn't take too much digging for anyone to get thier contact info.

I have enjoyed the company of so many of you. I wish everyone the best of

luck.