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Hi ,

Regarding the SSRI increasing OC's at first, might work, etc., that

is something I read here when I first joined years ago. I assume

it's knowledge picked up from reading, from doctor's

comments/observations repeated, experience, etc. I have read this

comment in posts in another group that doctors comment in. The

only " written " thing on it that I have (that I can find today!) is

at a website Q & A that I have saved. A part of which is:

" sbg1124: Is it possible for some SSRI's to make OCD worse?

Dr. Jenike: Yes. I think that, sometimes, worsening OCD symptoms

(not side effects) actually predicts a good response. That is if the

patient can stay on the drug long enough. It is a rare OCD patient

who continues to have worsening OCD on these drugs, but I have seen

it. Sometimes, the drugs help, but other times, they can make things

worse. "

http://www.healthyplace.com/Communities/Anxiety/site/transcripts/obse

ssions_ocd.asp

The same for where " sometimes people do better on a lower dose... "

is where I've read doctor responses to Q & A's/groups, etc. I've read

that several times, it seems like since I've been reading

these/other things over the years. I guess key words on things like

this are " some people. "

Now - I have to read up on extinction bursts, as you've mentioned

that here before and my mind is blank!

Later,

> I'm a little puzzled by the occasional mention that if a

medication initially increases OCD behaviors, that means it might be

the right med because what you're seeing is an " extinction burst. "

My daughter experienced extreme worsening of symptoms when put on

Zoloft, and neither psychiatrist who has seen her indicated that it

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Hi , I'm not sure the term " extinction burst " is quite right for the

phenomenon of initial worsening symptoms while taking SSRI that may predict

a good outcome. As you say, I *have* read that term to mean initial

worsening of OCD when starting behavior therapy.

However I can't recall any certain term that means initially worsening

symptoms when starting an SSRI. Like some of the others, I know I have read

of this possibility, and that some doctors believe it, including my child's

pdoc. I wonder if it may be a clinical observation rather than something

that has been proved by a controlled study.

There is a Herxheimer reaction (sp?) which has to do with initial worsening

symptoms when people take antiviral or maybe antibiotic therapy, but I don't

think that applies to SSRI medications. And I searched +ssri +paradoxical

which returned articles mostly having to do with the recent warnings re:

suicide ideation and so on.

Sorry not more help.

Kathy R. in Indiana

----- Original Message -----

From: " Price " <firecooklmp@...>

> I'm a little puzzled by the occasional mention that if a medication

> initially increases OCD behaviors, that means it might be the right med

> because what you're seeing is an " extinction burst. " My daughter

> experienced extreme worsening of symptoms when put on Zoloft, and neither

> psychiatrist who has seen her indicated that it might mean we were on the

> right track. The first decreased the dose (which was already very low),

> the second changed her to Prozac -- with which we saw improvement within a

> few days.

>

> Since I am a librarian in a med school library and have access to medical

> databases, I decided to check this out. I searched Medline, PsychInfo and

> some Evidence Based Medicine databases. Found things related to extinction

> of behavior, but they all seemed to relate to CBT/ERP and not meds or

> reaction to meds.

>

> Can anyone provide any kind of citation or other documents to support the

> " extinction burst " theory regarding meds? Just trying to get this clear in

> my own mind.

>

> Thanks,

> P. in NJ

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Hi,

When I tried to open the site it gave me this comment:

( Microsoft OLE DB Provider for ODBC Drivers error '80040e21'

Multiple-step OLE DB operation generated errors. Check each OLE DB status

value, if available. No work was done.

/site/error404.asp, line 115

In this case can I have any advice to how can I manage to open this site. Or

if somebody on this list is able to open it to copy & paste it & send it to

me please.

Thanks

Huda

>From: " " <@...>

>Reply-

>

>Subject: Re: extinction bursts

>Date: Wed, 04 May 2005 17:14:46 -0000

>

>Hi ,

>Regarding the SSRI increasing OC's at first, might work, etc., that

>is something I read here when I first joined years ago. I assume

>it's knowledge picked up from reading, from doctor's

>comments/observations repeated, experience, etc. I have read this

>comment in posts in another group that doctors comment in. The

>only " written " thing on it that I have (that I can find today!) is

>at a website Q & A that I have saved. A part of which is:

>

> " sbg1124: Is it possible for some SSRI's to make OCD worse?

>

>Dr. Jenike: Yes. I think that, sometimes, worsening OCD symptoms

>(not side effects) actually predicts a good response. That is if the

>patient can stay on the drug long enough. It is a rare OCD patient

>who continues to have worsening OCD on these drugs, but I have seen

>it. Sometimes, the drugs help, but other times, they can make things

>worse. "

>http://www.healthyplace.com/Communities/Anxiety/site/transcripts/obse

>ssions_ocd.asp

>

>The same for where " sometimes people do better on a lower dose... "

>is where I've read doctor responses to Q & A's/groups, etc. I've read

>that several times, it seems like since I've been reading

>these/other things over the years. I guess key words on things like

>this are " some people. "

>

>Now - I have to read up on extinction bursts, as you've mentioned

>that here before and my mind is blank!

>

>Later,

>

>

>

>

> > I'm a little puzzled by the occasional mention that if a

>medication initially increases OCD behaviors, that means it might be

>the right med because what you're seeing is an " extinction burst. "

>My daughter experienced extreme worsening of symptoms when put on

>Zoloft, and neither psychiatrist who has seen her indicated that it

>

>

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Guest guest

The psychiatrist who first diagnosed and prescribed medication for my

youngest daughter used this term. When first went on Paxil, her behavior

became more OCD than it had ever been at that time. It lasted about two weeks

after she started taking medication. She did not act impulsively or dangerously

as some children do when they are on the wrong medication. She cried more, had

more " Seeing Things " and was much more fearful than she had been before.

Immediately after that, she became quite well. She showed very few symptoms.

That lasted about a week. Two years later, my second daughter experienced the

same ups and downs when put on Zoloft. After the initial worsening and then

sudden improvement of symptoms, both girls leveled out to where they are now:

better but not symptom free. The doctor explained it to me by saying the when

the chemicals in the brain are messed with, they react. The chemicals in the

brain want to " right " themselves when they are disrupted and the OCD chemical

levels are all it knows. It wants to get back to what it is used to. He said

that it was perfectly normal and that many people experience it. My youngest

daughter has a crossing eye and when she was very young, her glasses broke

and her other eye started to cross. I called the doctor who was replacing the

glasses and he told me that her brain was just trying to get the vision it had

lost with the glasses broken back. I though of that when the doctor talked

about the brain chemicals. Once the glasses were fixed, the other eye stopped

crossing. I am still looking through the books I have to see if any of the

authors have written about extinction bursts due to meds but haven't found any

yet. I do trust this doctor and what he said to me made sense. I'll keep

looking! Kelley in NV

p.s. This is not to say that every bad reaction is a good indication that

the meds are working. Sometimes a med is just wrong for a child and if they are

showing dangerous behavior the doctor should be called! I'm talking about an

increase in symptoms my children already had.

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Guest guest

Hi, Huda

I initially had the same problem. The URL breaks onto a second line, so you have

to copy and paste it in two pieces.

P.

Huda Abi Rafeh <hudaarafeh@...> wrote:

Hi,

When I tried to open the site it gave me this comment:

( Microsoft OLE DB Provider for ODBC Drivers error '80040e21'

Multiple-step OLE DB operation generated errors. Check each OLE DB status

value, if available. No work was done.

/site/error404.asp, line 115

In this case can I have any advice to how can I manage to open this site. Or

if somebody on this list is able to open it to copy & paste it & send it to

me please.

Thanks

Huda

>From: " " <@...>

>Reply-

>

>Subject: Re: extinction bursts

>Date: Wed, 04 May 2005 17:14:46 -0000

>

>Hi ,

>Regarding the SSRI increasing OC's at first, might work, etc., that

>is something I read here when I first joined years ago. I assume

>it's knowledge picked up from reading, from doctor's

>comments/observations repeated, experience, etc. I have read this

>comment in posts in another group that doctors comment in. The

>only " written " thing on it that I have (that I can find today!) is

>at a website Q & A that I have saved. A part of which is:

>

> " sbg1124: Is it possible for some SSRI's to make OCD worse?

>

>Dr. Jenike: Yes. I think that, sometimes, worsening OCD symptoms

>(not side effects) actually predicts a good response. That is if the

>patient can stay on the drug long enough. It is a rare OCD patient

>who continues to have worsening OCD on these drugs, but I have seen

>it. Sometimes, the drugs help, but other times, they can make things

>worse. "

>http://www.healthyplace.com/Communities/Anxiety/site/transcripts/obse

>ssions_ocd.asp

>

>The same for where " sometimes people do better on a lower dose... "

>is where I've read doctor responses to Q & A's/groups, etc. I've read

>that several times, it seems like since I've been reading

>these/other things over the years. I guess key words on things like

>this are " some people. "

>

>Now - I have to read up on extinction bursts, as you've mentioned

>that here before and my mind is blank!

>

>Later,

>

>

>

>

> > I'm a little puzzled by the occasional mention that if a

>medication initially increases OCD behaviors, that means it might be

>the right med because what you're seeing is an " extinction burst. "

>My daughter experienced extreme worsening of symptoms when put on

>Zoloft, and neither psychiatrist who has seen her indicated that it

>

>

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http://www.worrywisekids.org ), Dan Geller, M.D.,Aureen Pinto Wagner, Ph.D., (

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Guest guest

Thanks, Kelley. I'll be looking forward to seeing what you find. In my

daughter's case, too, it was an increase in existing symptoms. But since she was

nearly non-functional to begin with, a severe increase was pretty hard to deal

with.

P.

kelleydinkins@... wrote:

The psychiatrist who first diagnosed and prescribed medication for my

youngest daughter used this term. When first went on Paxil, her behavior

became more OCD than it had ever been at that time. It lasted about two weeks

after she started taking medication. She did not act impulsively or dangerously

as some children do when they are on the wrong medication. She cried more, had

more " Seeing Things " and was much more fearful than she had been before.

Immediately after that, she became quite well. She showed very few symptoms.

That lasted about a week. Two years later, my second daughter experienced the

same ups and downs when put on Zoloft. After the initial worsening and then

sudden improvement of symptoms, both girls leveled out to where they are now:

better but not symptom free. The doctor explained it to me by saying the when

the chemicals in the brain are messed with, they react. The chemicals in the

brain want to " right " themselves when they are disrupted and the OCD chemical

levels are all it knows. It wants to get back to what it is used to. He said

that it was perfectly normal and that many people experience it. My youngest

daughter has a crossing eye and when she was very young, her glasses broke

and her other eye started to cross. I called the doctor who was replacing the

glasses and he told me that her brain was just trying to get the vision it had

lost with the glasses broken back. I though of that when the doctor talked

about the brain chemicals. Once the glasses were fixed, the other eye stopped

crossing. I am still looking through the books I have to see if any of the

authors have written about extinction bursts due to meds but haven't found any

yet. I do trust this doctor and what he said to me made sense. I'll keep

looking! Kelley in NV

p.s. This is not to say that every bad reaction is a good indication that

the meds are working. Sometimes a med is just wrong for a child and if they are

showing dangerous behavior the doctor should be called! I'm talking about an

increase in symptoms my children already had.

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