Re: Re: Metabolic Syndrome and Testosterone

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After testing more than once.CE Grim MDOn Jun 24, 2012, at 8:49 AM, wrote: And how is your level? > > > > > > > > > From: jclark24p@ > > > Subject: Metabolic Syndrome and Testosterone > > > hyperaldosteronism > > > Date: Saturday, June 23, 2012, 1:11 PM > > > > > > > > > > > >  > > > > > > > > > > > > > > > I was researching testosterone this morning as I continue to validate my decision of surgery instead of meds. (With my co-morbid conditions I do have a slightly elevated risk!) I came across this new study (March 2012) which sheds light on the issue (MAYBE) and may even be relevant to the Gordon, Stowasser, etal study I posted earlier. > > > I ask that you carefully read both with this question in mind: ¡°Is the medicines being used to treat IHA altering the outcome of the study? And maybe QOL?¡± In other words, I bet they are using Spironolactone and also hypothesize the outcome would be different if they used Eplerenone and didn¡¯t antagonize androgen! Dr. Grim, what do you think? Do you want to ¡°burst their bubble¡± or should I? (Probably more effective coming from you!) Also, are you ready to join me in recommending Eplerenone as the first (and only) choice and to hell with cost! > > > Ladies: Please note this paragraph: TESTOSTERONE AND METABOLIC SYNDROME - > > > ¡°There are a number of epidemiological studies linking T and MetS. Although there are a number of publications showing the association of T and MetS in females,[45¨C56] in this review we will restrict to the association in males.¡± I did not try to analyze ¡°the fairer sex¡± but the titles look like you could interpret and apply. (Momma told me a long time ago that I would never figure out a woman!) > > > ¡¡ > > > ¡°We found in our previous study higher occurrence of metabolic disturbances in patients with idiopathic hyperaldosteronism (IHA) compared to subjects with aldosterone-producing adenoma (APA).¡± > > > http://www.biomed.cas.cz/physiolres/pdf/prepress/932335.pdf > > > Testosterone and metabolic syndrome: The link ¡°Serum testosterone (T) has been shown to be associated with MetS. Several studies have shown a higher prevalence of MetS in subjects with low testosterone.¡± > > > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354945/?report=printable > > > Have you had your testosterone checked? I finally convinced my PCP to check mine in March, 2012, as near as I can tell the first time in 65 years! It was 1.26, range 1.95 - 11.36. I had been off Spironolactone for 3 months but it sure would be nice to know what it was before I started.  Might be worth checking a few that are on Spiro now and see if we can reduce MetS! Who does all the surveys? > > > > > >