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Increase in Inspra from 200 mg/day to 300 mg/day has decreased blood pressure

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After 3 weeks of increasing Inspra 50% from 100 mg AM and 100 mg PM to 150 mg AM and 150 mg PM my blood pressure has decreased from 140/90 to 127/85. It is a decrease of 9% on the systolic and 5 1/2% on the diastolic?Is this significant?> > > > >> > > > > > I am currently taking 100 mg of Inspra (eplerenone) in the> > > > morning and 100 mg of Inspra (eplerenone) at night with 5 mg of> > > > Norvasc (amlodipine) at night. I am also on the DASH diet. I am 30> > > > pounds overweight BMI 30, 5'6" and 191 pounds.> > > > > >> > > > > >> > > > > > My recent test results as of April 2012 on Inspra without salt> > > > loading are Renin 0.29 and Aldosterone 93. My blood potassium is > > 3.9> > > > and my urine potassium is 24.2> > > > > >> > > > > > My blood pressure is still an average of 140/90.> > > > > >> > > > > > Do you think it would lower my blood pressure if I took more> > > > Inspra such as 150 in the AM and 150 in the PM increasing my dose> > > > from 200 mg to 300 mg per day?> > > > > >> > > > > > Do you think it would be helpful and not dangerous to add> > > > Amiloride to the Inspra?> > > > > >> > > > > > Of course all this dosage changing would be under my doctor's> > > > advice and supervision.> > > > > >> > > > > > I just want to know if a larger dose of Inspra would be > > helpful> > > > in reducing my blood pressure to normal.> > > > > >> > > > > > If you have any experience with this or suggestions,> > > > recommendations or feedback, please reply.> > > > > >> > > > > > Thanks.> > > > > >> > > > >> > > >> > > >> > >> >> >>

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