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JC at NIH - PA/SCS

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This is the first report of a study of PA and Cortisol coexisting that I have found, it is from Japan. (There are others but I I don't have full access to them. Will have to get NIH to pay for that if they keep fooling around!)

"Clinicopathological features of primary aldosteronism associated with subclinical Cushingfs syndrome"

Source: https://www.jstage.jst.go.jp/article/endocrj/advpub/0/advpub_K10E-402/_pdf

Is 21% too many to miss by trial & error?

@

The prevalence of PA/SCS was 8 of 38 PA patients (21%) studied. These 8 PA/SCS patients were significantly older and had larger tumor, higher serum potassium levels, lower basal plasma levels of aldosterone, ACTH and DHEA-S as well as lower response of aldosterone after ACTH stimulation than those in 12 patients with aldosterone-producing adenoma without hypercortisolism.

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