Re: Polycythemia with PA? Spiro causing low sodium?

[Guest guest]

Salt is dangerous to you so who's to say that your Conn's isn't triggering and leading to the other diseases or making them worse? Maybe it's a cascade and maybe it is on you. So...You actually have the magic bullet, but as you say you don't want to do it. I guess that seems odd to me. I bet there are areas of your life you are very disciplined - like I bet you take your medicine on schedule, or you drink the same soda, or watch certain shows with some discipline. But when it comes to your life, and just cutting ONE single solitary thing like salt - DOWN - no one has to stop it completely, your excuse is you just won't do it, but you're also upset that your not getting better? Confusing.

I am incredibly aloof and hardly stick to anything, but I want to be there for my kids as they matter and so does my wife, so I decided to DASH. Not perfectly, and not fanatically, but enough I could get off the medicine for now. And I went years misdiagnosed and ignored by hundreds of medical professionals, my professional life has been completely ruined because of it, our finances are destroyed, and everyone has suffered because of it. But if I would have been more astute and realized something as simple as DASH in my past may have led me down a different path, I would have been there. But I didn't know. Not sure what is so appealing about a little salt anwyay. I don't miss one grain of it.

I don't know your tagline, so maybe your single and it isn't a big deal if you go or stay, I don't know, maybe we can't compare that way, but stop looking for the magic bullet as You might be holding it in your hands, like the sunglasses on top of our head we can't find.

From: Spalding <medgerly@...>Subject: Polycythemia with PA? Spiro causing low sodium?"hyperaldosteronism " <hyperaldosteronism >Date: Friday, May 18, 2012, 2:48 PM

Hello, Dr. Grim.

I have not written in some time. I was diagnosed with PA due to hyperplasia of both adrenals. I have my BP under control with 200 mg of Spironolactone per day plus 10 mg of lisinopril. No, I do not DASH, I'm sorry to say, because I have very poor self-discipline. However, my blood tests for the past six months or so are showing low or borderline sodium levels as well as chloride levels.

Other abnormalities are high hematocrit and high hemoglobin. I've been tested for polycythemia vera, but that has pretty much been ruled out. I see that early research linked Conn's syndrome to polycythemia, but I don't see much about it in the later literature. (I'm a medical librarian, so I do know how to search for these things.)

Do you think the polycythemia could be secondary to the PA?

Another possibility suggested by my ENT after seeing nasal destruction, low kidney GFR rate, and other symptoms is that I have an autoimmune inflammatory disorder such as Wegener's Granulomatosis. I will be seen at s Hopkins in July for that.

Just wondering whether any of these symptoms ring any bells for you. Could something like Wegener's have caused the hyperplasia of my adrenals? Supposedly it can attack any organ.

I just would like to get to the bottom of it all, as I'm suffering from severe fatigue. I also have hepatitis C, which I know has recently been associated with cryoglobulimia, so perhaps I should stop looking for a magic bullet. Still I'd be interested in your thoughts.

Thanks,

Frostburg, land

PA, adrenal hyperplasia

[Guest guest]

BTW, your blood sodium is not reflective of the salt intake and how it is affecting you. That in the big picture is nothing really as it relates to the salt that might be killing you slowly.

From: Spalding <medgerly@...>Subject: Polycythemia with PA? Spiro causing low sodium?"hyperaldosteronism " <hyperaldosteronism >Date: Friday, May 18, 2012, 2:48 PM

Hello, Dr. Grim.

I have not written in some time. I was diagnosed with PA due to hyperplasia of both adrenals. I have my BP under control with 200 mg of Spironolactone per day plus 10 mg of lisinopril. No, I do not DASH, I'm sorry to say, because I have very poor self-discipline. However, my blood tests for the past six months or so are showing low or borderline sodium levels as well as chloride levels.

Other abnormalities are high hematocrit and high hemoglobin. I've been tested for polycythemia vera, but that has pretty much been ruled out. I see that early research linked Conn's syndrome to polycythemia, but I don't see much about it in the later literature. (I'm a medical librarian, so I do know how to search for these things.)

Do you think the polycythemia could be secondary to the PA?

Another possibility suggested by my ENT after seeing nasal destruction, low kidney GFR rate, and other symptoms is that I have an autoimmune inflammatory disorder such as Wegener's Granulomatosis. I will be seen at s Hopkins in July for that.

Just wondering whether any of these symptoms ring any bells for you. Could something like Wegener's have caused the hyperplasia of my adrenals? Supposedly it can attack any organ.

I just would like to get to the bottom of it all, as I'm suffering from severe fatigue. I also have hepatitis C, which I know has recently been associated with cryoglobulimia, so perhaps I should stop looking for a magic bullet. Still I'd be interested in your thoughts.

Thanks,

Frostburg, land

PA, adrenal hyperplasia

[Guest guest]

Without numbers can't help. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn May 18, 2012, at 20:29, Bingham <jlkbbk2003@...> wrote:

BTW, your blood sodium is not reflective of the salt intake and how it is affecting you. That in the big picture is nothing really as it relates to the salt that might be killing you slowly.

From: Spalding <medgerly@...>Subject: Polycythemia with PA? Spiro causing low sodium?"hyperaldosteronism " <hyperaldosteronism >Date: Friday, May 18, 2012, 2:48 PM

Hello, Dr. Grim.

I have not written in some time. I was diagnosed with PA due to hyperplasia of both adrenals. I have my BP under control with 200 mg of Spironolactone per day plus 10 mg of lisinopril. No, I do not DASH, I'm sorry to say, because I have very poor self-discipline. However, my blood tests for the past six months or so are showing low or borderline sodium levels as well as chloride levels.

Other abnormalities are high hematocrit and high hemoglobin. I've been tested for polycythemia vera, but that has pretty much been ruled out. I see that early research linked Conn's syndrome to polycythemia, but I don't see much about it in the later literature. (I'm a medical librarian, so I do know how to search for these things.)

Do you think the polycythemia could be secondary to the PA?

Another possibility suggested by my ENT after seeing nasal destruction, low kidney GFR rate, and other symptoms is that I have an autoimmune inflammatory disorder such as Wegener's Granulomatosis. I will be seen at s Hopkins in July for that.

Just wondering whether any of these symptoms ring any bells for you. Could something like Wegener's have caused the hyperplasia of my adrenals? Supposedly it can attack any organ.

I just would like to get to the bottom of it all, as I'm suffering from severe fatigue. I also have hepatitis C, which I know has recently been associated with cryoglobulimia, so perhaps I should stop looking for a magic bullet. Still I'd be interested in your thoughts.

Thanks,

Frostburg, land

PA, adrenal hyperplasia

[Guest guest]

Lisinopril will not have much effect with PA. NOT aware of high Hct due to Conn's. Trust u. Ever smoked. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn May 18, 2012, at 20:26, Bingham <jlkbbk2003@...> wrote:

Salt is dangerous to you so who's to say that your Conn's isn't triggering and leading to the other diseases or making them worse? Maybe it's a cascade and maybe it is on you. So...You actually have the magic bullet, but as you say you don't want to do it. I guess that seems odd to me. I bet there are areas of your life you are very disciplined - like I bet you take your medicine on schedule, or you drink the same soda, or watch certain shows with some discipline. But when it comes to your life, and just cutting ONE single solitary thing like salt - DOWN - no one has to stop it completely, your excuse is you just won't do it, but you're also upset that your not getting better? Confusing.

I am incredibly aloof and hardly stick to anything, but I want to be there for my kids as they matter and so does my wife, so I decided to DASH. Not perfectly, and not fanatically, but enough I could get off the medicine for now. And I went years misdiagnosed and ignored by hundreds of medical professionals, my professional life has been completely ruined because of it, our finances are destroyed, and everyone has suffered because of it. But if I would have been more astute and realized something as simple as DASH in my past may have led me down a different path, I would have been there. But I didn't know. Not sure what is so appealing about a little salt anwyay. I don't miss one grain of it.

I don't know your tagline, so maybe your single and it isn't a big deal if you go or stay, I don't know, maybe we can't compare that way, but stop looking for the magic bullet as You might be holding it in your hands, like the sunglasses on top of our head we can't find.

From: Spalding <medgerly@...>Subject: Polycythemia with PA? Spiro causing low sodium?"hyperaldosteronism " <hyperaldosteronism >Date: Friday, May 18, 2012, 2:48 PM

Hello, Dr. Grim.

I have not written in some time. I was diagnosed with PA due to hyperplasia of both adrenals. I have my BP under control with 200 mg of Spironolactone per day plus 10 mg of lisinopril. No, I do not DASH, I'm sorry to say, because I have very poor self-discipline. However, my blood tests for the past six months or so are showing low or borderline sodium levels as well as chloride levels.

Other abnormalities are high hematocrit and high hemoglobin. I've been tested for polycythemia vera, but that has pretty much been ruled out. I see that early research linked Conn's syndrome to polycythemia, but I don't see much about it in the later literature. (I'm a medical librarian, so I do know how to search for these things.)

Do you think the polycythemia could be secondary to the PA?

Another possibility suggested by my ENT after seeing nasal destruction, low kidney GFR rate, and other symptoms is that I have an autoimmune inflammatory disorder such as Wegener's Granulomatosis. I will be seen at s Hopkins in July for that.

Just wondering whether any of these symptoms ring any bells for you. Could something like Wegener's have caused the hyperplasia of my adrenals? Supposedly it can attack any organ.

I just would like to get to the bottom of it all, as I'm suffering from severe fatigue. I also have hepatitis C, which I know has recently been associated with cryoglobulimia, so perhaps I should stop looking for a magic bullet. Still I'd be interested in your thoughts.

Thanks,

Frostburg, land

PA, adrenal hyperplasia