Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 yea but not much.Worry about the big thinks salt and potassium intake.CE Grim MDOn May 14, 2012, at 7:59 AM, Francis Bill SUSPECTED PA wrote: Doesn't CA effect how K moves in and out of blood? > > > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like 190 > > over > > > > 115. > > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it was > > > > below acceptable > > > > > > > > > > range. PP put me on K and Magn and those seem in range > > > > now ! She > > > > > > > > > > wanted me to eat more calcium so I tried cottage > > cheese > > > > etc and this > > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is > > what I > > > > have . > > > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical lab > > > > tests so I can > > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 I was once told by a doctor that I had CKD3. This was the doctor that argued with me that I had uncontrolled HTN for 50 minutes and tried to put me on an ACE inhibitor. (We all know how well that would work when my renin is .1, right! I DID NOT HAVE MUCH FAITH IN THAT " DOCTOR " !) I have since been told by 3 doctors that I respect, Drs. Webster, Nice and Moraitis, that my kidney function is fine. In fact, Dr. Webster removed the reference to CKD3 from my record! To put your mind at ease I ran the numbers this morning, 10 samples back to 12/29/2010. Averages with nothing ever being out of range: CREATININE (0.5-1.5) = .943 eGFR ( >60) = 82 BUN (7-25) = 23 (7 samples while on Spironolactone) = 13 (3 samples while off Spironolactone) (You did remember that Spironolactone affected BUN, right) While I was at it I ran POTASSIUM (3.5-5.0) 7 samples while on Spironolactone average = 4.71 3 samples while off Spironolactone average = 4.13 Thank-you for your concern, can we end this " witch hunt " now? ..... > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like 190 over 115. > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it was below acceptable > > > > > > > > range. PP put me on K and Magn and those seem in range now ! She > > > > > > > > wanted me to eat more calcium so I tried cottage cheese etc and this > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is what I have . > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical lab tests so I can > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 Does that include 24 hr urine for Na, K and creatinine and aldosterone on same day?CE Grim MDOn May 14, 2012, at 9:52 AM, Francis Bill SUSPECTED PA wrote: Last time I checked Mayo lab was charging about $200 to do ARP. > > > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like 190 > > over > > > > 115. > > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it was > > > > below acceptable > > > > > > > > > > range. PP put me on K and Magn and those seem in range > > > > now ! She > > > > > > > > > > wanted me to eat more calcium so I tried cottage > > cheese > > > > etc and this > > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is > > what I > > > > have . > > > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical lab > > > > tests so I can > > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 Dr. Grim, I only referenced those articles because they addressed the potassium issue in more detail. > > > > > > > > > From: Bingham <jlkbbk2003@> > > > Subject: Re: Re: Blood pressure has been > > spiking the past month Looks like sodium sensitivity > > > hyperaldosteronism > > > Date: Monday, May 14, 2012, 1:30 AM > > > > > > > > > > > >  > > > > > > > > > > > > > > > > > > > > > > > > What  are the thoughts on why they not low K? What was the > > theory behind those with normal K , yet have Conn's? because we > > must be identifying the Conn's based on chronic HTN resistant to > > meds other than MCB's, and then high aldosterone levels and the > > aldo/ renin ratio. Something had to bring to the identifying table. > > Was it the resistant HTN only? > > > > > > --- > > > > > > > > > > > >  > > > > > > > > > > > > > > >  > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 At one time I recall you were on other meds that will lower eGFR (ACE,ARBS): as do most drugs when BP is first lowered after being high for a long time. In most the K function improves as the kidney heals one the BP is controlled and aldo blocked and diet Na lowered.I recommend that folks keep a running plot of 1/CR of 1 over eGFR to follow trend over time.Other insults can bump down eGFR such as CT or MRI scans, antibiotics, NSAIDs to mention a few. CE Grim MDOn May 14, 2012, at 10:08 AM, wrote: I was once told by a doctor that I had CKD3. This was the doctor that argued with me that I had uncontrolled HTN for 50 minutes and tried to put me on an ACE inhibitor. (We all know how well that would work when my renin is .1, right! I DID NOT HAVE MUCH FAITH IN THAT "DOCTOR"!) I have since been told by 3 doctors that I respect, Drs. Webster, Nice and Moraitis, that my kidney function is fine. In fact, Dr. Webster removed the reference to CKD3 from my record! To put your mind at ease I ran the numbers this morning, 10 samples back to 12/29/2010. Averages with nothing ever being out of range: CREATININE (0.5-1.5) = .943 eGFR ( >60) = 82 BUN (7-25) = 23 (7 samples while on Spironolactone) = 13 (3 samples while off Spironolactone) (You did remember that Spironolactone affected BUN, right) While I was at it I ran POTASSIUM (3.5-5.0) 7 samples while on Spironolactone average = 4.71 3 samples while off Spironolactone average = 4.13 Thank-you for your concern, can we end this "witch hunt" now? .... > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like 190 over 115. > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it was below acceptable > > > > > > > > range. PP put me on K and Magn and those seem in range now ! She > > > > > > > > wanted me to eat more calcium so I tried cottage cheese etc and this > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is what I have . > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical lab tests so I can > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 Thanks. They are good short articles and one of the few that mention that low sodium diet may be all that is needed to control BP. I did send them a note recommending they refer their patients here if they are interested. But email may not be good. CE Grim MDOn May 14, 2012, at 10:17 AM, wrote: Dr. Grim, I only referenced those articles because they addressed the potassium issue in more detail. > > > > > > > > > From: Bingham <jlkbbk2003@> > > > Subject: Re: Re: Blood pressure has been > > spiking the past month Looks like sodium sensitivity > > > hyperaldosteronism > > > Date: Monday, May 14, 2012, 1:30 AM > > > > > > > > > > > >  > > > > > > > > > > > > > > > > > > > > > > > > What  are the thoughts on why they not low K? What was the > > theory behind those with normal K , yet have Conn's? because we > > must be identifying the Conn's based on chronic HTN resistant to > > meds other than MCB's, and then high aldosterone levels and the > > aldo/ renin ratio. Something had to bring to the identifying table. > > Was it the resistant HTN only? > > > > > > --- > > > > > > > > > > > >  > > > > > > > > > > > > > > >  > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 I do not look at this as a " witch hunt " but as a way to help others If by something you or others post helps someone else they that is a good thing. If you have no interest in doing this then I will no longer ask you questions. > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like 190 over 115. > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it was below acceptable > > > > > > > > > range. PP put me on K and Magn and those seem in range now ! She > > > > > > > > > wanted me to eat more calcium so I tried cottage cheese etc and this > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is what I have .. > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical lab tests so I can > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 Lets say one has real K of 3.3 and blood draw shows it 3.8 can this be do to CA blocking? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like > > 190 > > > > over > > > > > > 115. > > > > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it > > was > > > > > > below acceptable > > > > > > > > > > > > range. PP put me on K and Magn and those seem in > > range > > > > > > now ! She > > > > > > > > > > > > wanted me to eat more calcium so I tried cottage > > > > cheese > > > > > > etc and this > > > > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is > > > > what I > > > > > > have . > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical > > lab > > > > > > tests so I can > > > > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 Not likely. Never heard of it. But maybe someone else knows.CE Grim MDOn May 14, 2012, at 10:57 AM, Francis Bill SUSPECTED PA wrote: Lets say one has real K of 3.3 and blood draw shows it 3.8 can this be do to CA blocking? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like > > 190 > > > > over > > > > > > 115. > > > > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it > > was > > > > > > below acceptable > > > > > > > > > > > > range. PP put me on K and Magn and those seem in > > range > > > > > > now ! She > > > > > > > > > > > > wanted me to eat more calcium so I tried cottage > > > > cheese > > > > > > etc and this > > > > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is > > > > what I > > > > > > have . > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical > > lab > > > > > > tests so I can > > > > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 I don't mind you asking questions but we have been over this subject many times and the answer hasn't changed. If you ask Mom and the answer is NO and you ask Dad and the answer is NO you can assume the answer is NO! If I get a different answer from NIH or anybody else you can be sure I will report it. > > > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control like 190 over 115. > > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and it was below acceptable > > > > > > > > > > range. PP put me on K and Magn and those seem in range now ! She > > > > > > > > > > wanted me to eat more calcium so I tried cottage cheese etc and this > > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if this is what I have . > > > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of medical lab tests so I can > > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 , I also struggled with this question (my wrongly drawn K never below 3.7). Yet, almost every day I have muscle twitching and spasm which are not showing up in the labs. I BELIEVE (and I am NOT a doctor) that we ARE truly K depleted on the intracellular level but not on the extracellular (circulating blood K are low but more-or-less normal). A while back a member here Alison Rowe explained something which was very interesting to me: insulin can push K in and out of muscles hence intracellular-extracellular shifts can happen very rapidly if your pancreas releases insulin. So I think that after a low K crisis (like heart palpitations) the body will enter some panic mode re-distributing K (via intra-extra cellular shifts mediated by insulin) to the more important organs (like heart, lungs, etc) hence the BLOOD K concentration will always be " normal " yet the " less important " parts (legs, hands etc) will be K depleted. BTW from what I've read >90% of the potassium is stored intra-cellular and only <10% is in circulation. Please voice your opinion if you think I am wrong. PS. This seems to also explain why PA comes with insulin resistance. > Jeeze louise.....I swear Englsh is my native language. I don't know how I wrote that below, but I meant to say " what are the thoughts on why some with Conn's are not low K? " >  > What was the thinking on why some do and some don't? Just curious. >  Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2012 Report Share Posted May 14, 2012 Could also be a connection why so many with PA also report hypoglycemic episodes and the drops after meals or the swimmy heads after lunch etc. I think that this is usully due to their body releasing too much insulin, likely because we eat high carbs as youth and especially in our teens (but tend to much more active too), and once we change a little or try to change as adults and do less carbs, we still have a body that pumps out the insulin like it used to and depletes our blood sugars quickly. That makes some sense. Like you I know the now the hard way exactly what my low K feels like and I have had it normal lately, but knew it was low, and one time the tech argued with me about the "how it's the speed of the draw" and used the tourniquet anyway, and it came up normal, but I KNEW it was low. I took K, and symptoms went away. From: lvasiliu@... <lvasiliu@...>Subject: Re: Blood pressure has been spiking the past month Looks like sodium sensitivityhyperaldosteronism Date: Monday, May 14, 2012, 12:55 PM , I also struggled with this question (my wrongly drawn K never below 3.7).Yet, almost every day I have muscle twitching and spasm which are not showing up in the labs.I BELIEVE (and I am NOT a doctor) that we ARE truly K depleted on the intracellular level but not on the extracellular (circulating blood K are low but more-or-less normal). A while back a member here Alison Rowe explained something which was very interesting to me: insulin can push K in and out of muscles hence intracellular-extracellular shifts can happen very rapidly if your pancreas releases insulin.So I think that after a low K crisis (like heart palpitations) the body will enter some panic mode re-distributing K (via intra-extra cellular shifts mediated by insulin) to the more important organs (like heart, lungs, etc) hence the BLOOD K concentration will always be "normal" yet the "less important" parts (legs, hands etc) will be K depleted.BTW from what I've read >90% of the potassium is stored intra-cellular and only <10% is in circulation.Please voice your opinion if you think I am wrong.PS. This seems to also explain why PA comes with insulin resistance.> Jeeze louise.....I swear Englsh is my native language. I don't know how I wrote that below, but I meant to say "what are the thoughts on why some with Conn's are not low K?"> Â > What was the thinking on why some do and some don't? Just curious.> Â Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2012 Report Share Posted May 15, 2012 Hypokalemia decreases insulin release. Recommend reading some of Dr. Conn's works on diabetes and PA and hypocalemia.An excellent resource for doing this is Google Scholar. Many of the original references have been scanned in and can be read. Great resource.CE Grim MDOn May 14, 2012, at 2:33 PM, Bingham wrote: Could also be a connection why so many with PA also report hypoglycemic episodes and the drops after meals or the swimmy heads after lunch etc. I think that this is usully due to their body releasing too much insulin, likely because we eat high carbs as youth and especially in our teens (but tend to much more active too), and once we change a little or try to change as adults and do less carbs, we still have a body that pumps out the insulin like it used to and depletes our blood sugars quickly. That makes some sense. Like you I know the now the hard way exactly what my low K feels like and I have had it normal lately, but knew it was low, and one time the tech argued with me about the "how it's the speed of the draw" and used the tourniquet anyway, and it came up normal, but I KNEW it was low. I took K, and symptoms went away. From: lvasiliu@... <lvasiliu@...>Subject: Re: Blood pressure has been spiking the past month Looks like sodium sensitivityhyperaldosteronism Date: Monday, May 14, 2012, 12:55 PM , I also struggled with this question (my wrongly drawn K never below 3.7).Yet, almost every day I have muscle twitching and spasm which are not showing up in the labs.I BELIEVE (and I am NOT a doctor) that we ARE truly K depleted on the intracellular level but not on the extracellular (circulating blood K are low but more-or-less normal). A while back a member here Alison Rowe explained something which was very interesting to me: insulin can push K in and out of muscles hence intracellular-extracellular shifts can happen very rapidly if your pancreas releases insulin.So I think that after a low K crisis (like heart palpitations) the body will enter some panic mode re-distributing K (via intra-extra cellular shifts mediated by insulin) to the more important organs (like heart, lungs, etc) hence the BLOOD K concentration will always be "normal" yet the "less important" parts (legs, hands etc) will be K depleted.BTW from what I've read >90% of the potassium is stored intra-cellular and only <10% is in circulation.Please voice your opinion if you think I am wrong.PS. This seems to also explain why PA comes with insulin resistance.> Jeeze louise.....I swear Englsh is my native language. I don't know how I wrote that below, but I meant to say "what are the thoughts on why some with Conn's are not low K?"> Â > What was the thinking on why some do and some don't? Just curious.> Â Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2012 Report Share Posted May 15, 2012 Studies I have seen on are not real clear on this. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > The spikes have been hard to control > > like > > > > 190 > > > > > > over > > > > > > > > 115. > > > > > > > > > > > > > > Doubling and tripling meds ! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > In December I had Potassium tested and > > it > > > > was > > > > > > > > below acceptable > > > > > > > > > > > > > > range. PP put me on K and Magn and those > > seem in > > > > range > > > > > > > > now ! She > > > > > > > > > > > > > > wanted me to eat more calcium so I tried > > cottage > > > > > > cheese > > > > > > > > etc and this > > > > > > > > > > > > > > improved diet may be nearly killing me ! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Ran across this site again and .... > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Looks I need to be tested to see if > > this is > > > > > > what I > > > > > > > > have . > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Which file has the best outline of > > medical > > > > lab > > > > > > > > tests so I can > > > > > > > > > > > > > > communicate with my doctor? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thanks K > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2012 Report Share Posted May 15, 2012 All of these signs and symptoms just intermingle I think. I have insulin resistance- my insulin levels are very high. For years and years I have had hypoglycemia . I have not been officially dx as PA but only Inspra brings my BP done. Phyllis On 5/15/2012 11:38 AM, Clarence Grim wrote:  Hypokalemia decreases insulin release.  Recommend reading some of Dr. Conn's works on diabetes and PA and hypocalemia. An excellent resource for doing this is Google Scholar. Many of the original references have been scanned in and can be read.  Great resource. CE Grim MD On May 14, 2012, at 2:33 PM, Bingham wrote:  Could also be a connection why so many with PA also report hypoglycemic episodes and the drops after meals or the swimmy heads after lunch etc. I think that this is usully due to their body releasing too much insulin, likely because we eat high carbs as youth and especially in our teens (but tend to much more active too), and once we change a little or try to change as adults and do less carbs, we still have a body that pumps out the insulin like it used to and depletes our blood sugars quickly.  That makes some sense.  Like you I know the now the hard way exactly what my low K feels like and I have had it normal lately, but knew it was low, and one time the tech argued with me about the "how it's the speed of the draw" and used the tourniquet anyway, and it came up normal, but I KNEW it was low. I took K, and symptoms went away.   From: lvasiliu@... <lvasiliu@...> Subject: Re: Blood pressure has been spiking the past month Looks like sodium sensitivity hyperaldosteronism Date: Monday, May 14, 2012, 12:55 PM  , I also struggled with this question (my wrongly drawn K never below 3.7). Yet, almost every day I have muscle twitching and spasm which are not showing up in the labs. I BELIEVE (and I am NOT a doctor) that we ARE truly K depleted on the intracellular level but not on the extracellular (circulating blood K are low but more-or-less normal). A while back a member here Alison Rowe explained something which was very interesting to me: insulin can push K in and out of muscles hence intracellular-extracellular shifts can happen very rapidly if your pancreas releases insulin. So I think that after a low K crisis (like heart palpitations) the body will enter some panic mode re-distributing K (via intra-extra cellular shifts mediated by insulin) to the more important organs (like heart, lungs, etc) hence the BLOOD K concentration will always be "normal" yet the "less important" parts (legs, hands etc) will be K depleted. BTW from what I've read >90% of the potassium is stored intra-cellular and only <10% is in circulation. Please voice your opinion if you think I am wrong. PS. This seems to also explain why PA comes with insulin resistance. > Jeeze louise.....I swear Englsh is my native language. I don't know how I wrote that below, but I meant to say "what are the thoughts on why some with Conn's are not low K?" >  > What was the thinking on why some do and some don't? Just curious. >  Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2012 Report Share Posted May 15, 2012 Thank is diagnostic enough for me. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn May 15, 2012, at 13:03, Phyllis <phylisrn@...> wrote: All of these signs and symptoms just intermingle I think. I have insulin resistance- my insulin levels are very high. For years and years I have had hypoglycemia . I have not been officially dx as PA but only Inspra brings my BP done. Phyllis On 5/15/2012 11:38 AM, Clarence Grim wrote: Hypokalemia decreases insulin release. Recommend reading some of Dr. Conn's works on diabetes and PA and hypocalemia. An excellent resource for doing this is Google Scholar. Many of the original references have been scanned in and can be read. Great resource. CE Grim MD On May 14, 2012, at 2:33 PM, Bingham wrote: Could also be a connection why so many with PA also report hypoglycemic episodes and the drops after meals or the swimmy heads after lunch etc. I think that this is usully due to their body releasing too much insulin, likely because we eat high carbs as youth and especially in our teens (but tend to much more active too), and once we change a little or try to change as adults and do less carbs, we still have a body that pumps out the insulin like it used to and depletes our blood sugars quickly. That makes some sense. Like you I know the now the hard way exactly what my low K feels like and I have had it normal lately, but knew it was low, and one time the tech argued with me about the "how it's the speed of the draw" and used the tourniquet anyway, and it came up normal, but I KNEW it was low. I took K, and symptoms went away. From: lvasiliu@... <lvasiliu@...> Subject: Re: Blood pressure has been spiking the past month Looks like sodium sensitivity hyperaldosteronism Date: Monday, May 14, 2012, 12:55 PM , I also struggled with this question (my wrongly drawn K never below 3.7). Yet, almost every day I have muscle twitching and spasm which are not showing up in the labs. I BELIEVE (and I am NOT a doctor) that we ARE truly K depleted on the intracellular level but not on the extracellular (circulating blood K are low but more-or-less normal). A while back a member here Alison Rowe explained something which was very interesting to me: insulin can push K in and out of muscles hence intracellular-extracellular shifts can happen very rapidly if your pancreas releases insulin. So I think that after a low K crisis (like heart palpitations) the body will enter some panic mode re-distributing K (via intra-extra cellular shifts mediated by insulin) to the more important organs (like heart, lungs, etc) hence the BLOOD K concentration will always be "normal" yet the "less important" parts (legs, hands etc) will be K depleted. BTW from what I've read >90% of the potassium is stored intra-cellular and only <10% is in circulation. Please voice your opinion if you think I am wrong. PS. This seems to also explain why PA comes with insulin resistance. > Jeeze louise.....I swear Englsh is my native language. I don't know how I wrote that below, but I meant to say "what are the thoughts on why some with Conn's are not low K?" > Â > What was the thinking on why some do and some don't? Just curious. > Â Reply to sender | Reply to group | Reply via web post | Start a New Topic Messages in this topic (41) .. __, Quote Link to comment Share on other sites More sharing options...
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