Re: PA with Cosecretion of Cortisol

[Guest guest]

Good to hear good data does not go bad. Our Indiana group abandoned the PST AFTER A prospecFive study of maybe 30 pts. With PA. We did not have CT THEN OF course in most. About 1980 is MY recollection. We also tested a number using an over night dex suppression as a good screen for GRA. With GRA ALDO goes to very low levels. I still use this. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn Mar 30, 2012, at 18:46, <jclark24p@...> wrote:

We recently had a short discussion on this subject. I happened on another mention and here is the takeaway:

"Evidence of cosecretion of cortisol occurred in 14% of patients." and "A significant minority of patients with PA exhibit evidence of cortisol cosecretion, which may have implications for perioperative management."

I only have access to the abstract, here it is:

source: http://www.ncbi.nlm.nih.gov/pubmed/21895732

title: A prospective evaluation of postural stimulation testing, computed tomography and adrenal vein sampling in the differential diagnosis of primary aldosteronism.

Dr. Grim, this is a Feb. 2012 study. Is this a recent finding they are starting to find and document?