Interesting news on brain fog in PA.

[Guest guest]

Cleaning out my office and just reread Dr. Conn's original report again and a 3 month followup after surgery.J Clin Lab Med 45:661-664 1955 Progress Report: Primary Aldosteronism, Jerome W. Conn, Ann Arbor, Michp 663"c. Symptomatic changes: The patient is now entirely asymptomatic. The disturbing polydipsia, polyuria and nocturia are gone. Muscular weakness has disappeared completely, as has symptomatic tetany. ....The patient states that in retrospect she in now aware that her "thinking processes" were greatly impaired before her operation. No objective change, however, can be observed." I bolded the text. I have probably read this report 10 times in the past and never noted the comment on "thinking Processes" until now but it struck me like a bolt of lightning. Suspect this was what we now call "brain fog". My guess is that the objective testing was not detailed at that time. What we need is a series of detailed mental process testing before and after surgery or DASH/MCB. FMRI studies would also be on interest. Will contact the NIH team as when folks are there they have lots of hang around time for testing. I almost certainly would not have noted this on rereading again unless I had been sensitized to the issue by our group here.Thanks again to all discussants of the issue here and I will add this to my next update on the evolution of PA. So all out there you can report to your Internist, Cards, or Endo that you have noted that your "thinking processes" have been greatly impared, AKA brain fog. Just like the first PA patient reported. I will write to the Journal and request permission for us to post the entire series of articles by Dr. Conn that were in the J Lab and Clin Med.in 1955.More on an "old" article on adrenal pathology in an autopsy series from 1969.I want to thank you all again. Keep up the good work.CE Grim MD CE Grim MD

[Guest guest]

Don't think this is new to you as you have posted about some having problem

doing check book. It is the term brainfog that became a new term that has been

used to decribe both a feeling and thought process.

Now is it a SX or sign that you could have PA?

>

> Cleaning out my office and just reread Dr. Conn's original report

> again and a 3 month followup after surgery.

>

> J Clin Lab Med 45:661-664 1955

> Progress Report: Primary Aldosteronism, Jerome W. Conn, Ann Arbor, Mich

>

> p 663

>

> " c. Symptomatic changes: The patient is now entirely asymptomatic.

> The disturbing polydipsia, polyuria and nocturia are gone. Muscular

> weakness has disappeared completely, as has symptomatic

> tetany. ....The patient states that in retrospect she in now aware

> that her " thinking processes " were greatly impaired before her

> operation. No objective change, however, can be observed. "

>

> I bolded the text. I have probably read this report 10 times in the

> past and never noted the comment on " thinking Processes " until now but

> it struck me like a bolt of lightning.

>

> Suspect this was what we now call " brain fog " . My guess is that the

> objective testing was not detailed at that time. What we need is a

> series of detailed mental process testing before and after surgery or

> DASH/MCB. FMRI studies would also be on interest. Will contact the

> NIH team as when folks are there they have lots of hang around time

> for testing.

>

> I almost certainly would not have noted this on rereading again unless

> I had been sensitized to the issue by our group here.

>

> Thanks again to all discussants of the issue here and I will add this

> to my next update on the evolution of PA.

>

> So all out there you can report to your Internist, Cards, or Endo that

> you have noted that your " thinking processes " have been greatly

> impared, AKA brain fog. Just like the first PA patient reported.

>

> I will write to the Journal and request permission for us to post the

> entire series of articles by Dr. Conn that were in the J Lab and Clin

> Med.in 1955.

>

> More on an " old " article on adrenal pathology in an autopsy series

> from 1969.

>

> I want to thank you all again.

>

> Keep up the good work.

>

> CE Grim MD

>

> CE Grim MD

>

[Guest guest]

Before I always attributed the problems to the many meds people were on before surgery for RAS or PA. Anyway we need to add it to the list of advanced PA. With severe low K mostly I would think. CE Grim MDOn May 8, 2012, at 8:31 AM, Francis Bill SUSPECTED PA wrote: Don't think this is new to you as you have posted about some having problem doing check book. It is the term brainfog that became a new term that has been used to decribe both a feeling and thought process. Now is it a SX or sign that you could have PA? > > Cleaning out my office and just reread Dr. Conn's original report > again and a 3 month followup after surgery. > > J Clin Lab Med 45:661-664 1955 > Progress Report: Primary Aldosteronism, Jerome W. Conn, Ann Arbor, Mich > > p 663 > > "c. Symptomatic changes: The patient is now entirely asymptomatic. > The disturbing polydipsia, polyuria and nocturia are gone. Muscular > weakness has disappeared completely, as has symptomatic > tetany. ....The patient states that in retrospect she in now aware > that her "thinking processes" were greatly impaired before her > operation. No objective change, however, can be observed." > > I bolded the text. I have probably read this report 10 times in the > past and never noted the comment on "thinking Processes" until now but > it struck me like a bolt of lightning. > > Suspect this was what we now call "brain fog". My guess is that the > objective testing was not detailed at that time. What we need is a > series of detailed mental process testing before and after surgery or > DASH/MCB. FMRI studies would also be on interest. Will contact the > NIH team as when folks are there they have lots of hang around time > for testing. > > I almost certainly would not have noted this on rereading again unless > I had been sensitized to the issue by our group here. > > Thanks again to all discussants of the issue here and I will add this > to my next update on the evolution of PA. > > So all out there you can report to your Internist, Cards, or Endo that > you have noted that your "thinking processes" have been greatly > impared, AKA brain fog. Just like the first PA patient reported. > > I will write to the Journal and request permission for us to post the > entire series of articles by Dr. Conn that were in the J Lab and Clin > Med.in 1955. > > More on an "old" article on adrenal pathology in an autopsy series > from 1969. > > I want to thank you all again. > > Keep up the good work. > > CE Grim MD > > CE Grim MD >