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Phyto and environmental estrogens

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Jaideep Mukherjee wrote:

Different authors have different takes on this issue. Dr. Eugene Shippen

endorses the use of soy protein for its many benefits, including lowering

cancer rates. The Okinawan Diet Plan book also talks, with scientific

evidence, about the use and benefits of soy products, tofu, etc., and the

much lower age-related diseases in Okinawa, for both males and females,

along with high longevity. The important point is that soy isoflavones are

phytoestrogens " very similar in chemical structure to human estrogens but

far weaker. Typically such estrogens have only about 1/500 the active effect

of estradiol, the most active human estrogen (Shippen). " High levels of

(weaker) soy phytoestrogens compete with the female hormone for receptor

sites in your body (male and female).

Bottom line is that it is better to ingest a weaker form of phytoestrogen

such as in soy products to fill up these receptor sites <snip>

Casler writes:

Hi Jaideep,

What evidence is presented that the weaker phytoestrogen will (in fact) be

" preferred " and as you say " fill up these receptor sites " ?

Is there some explained physiological mechanism of preferential reception to

the weaker forms when placed in competition with stronger estrogens?

Regards,

Casler

TRI-VECTOR 3-D Force Systems

Century City, CA

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