[CoMeD] PR: Routine Testing Confirms Elevated Male Hormones in Autism

[Guest guest]

ALL,

The attached press release (PR) discusses a

newly published peer-reviewed study which

confirms the elevation of the levels of male

hormones in children with an ASD diagnosis.

For those who do not/cannot receive file

attachments, the test version of this PR

is as follows:

>

>Routine Testing Confirms Elevated Male

>Hormones in Autism

>

>Release Contacts:

>For Immediate Release CoMeD President

>November 28, 2007 [Rev. K. Sykes (Richmond, VA)

> 804-364-8426]

> CoMeD Sci. Advisor

> [Dr. King (Lake Hiawatha, NJ)

> 973-263-4843]

>

>WASHINGTON, DC - A new moderate-scale

>peer-reviewed scientific/medical study

>confirms many patients with an autistic

>spectrum disorder (ASD) suffer from

>significantly elevated levels of male

>hormones, and numerous treatments that

>lower male-hormone levels have significantly

>improved clinical outcomes in patients

>with an ASD.

>

>This study, " A Prospective Assessment of

>Androgen Levels in Patients with Autistic

>Spectrum Disorders: Biochemical Underpinnings

>and Suggested Therapies, " by Mr. A.

>Geier and Dr. Mark R. Geier, has been

>published in the most recent issue of

>Neuroendocrinology Letters (Volume 28,

>Issue 5, pgs. 565-573). A grant from the

>Brenen Hornstein Autism Research & Education

>(BHARE) Foundation (Elk Grove, IL) to the

>Institute of Chronic Illnesses, Inc. (Silver

>Spring, MD) funded this research.

>

>Previous studies by Tordjman et al. (1997)

>and Geier and Geier (2006) have suggested

>patients with an ASD have elevated levels

>of male hormones. The male hormones tested

>in the Geier and Geier (2007) study were:

>testosterone, dehydroepiandrosterone (DHEA),

>and androstenedione.

>

>This study utilized blood testing to assess

>the level of these male hormones in patients

>diagnosed with an ASD. The researchers examined

>70 patients diagnosed with an ASD who were

>subsequently found to have elevated male-hormone

>levels by the CLIA-approved US Laboratory

>Corporation of America (LabCorp).

>

>The findings by Geier and Geier demonstrate:

>· Patients with an ASD had significantly

> increased levels of serum testosterone,

> serum free testosterone, percent free

> testosterone, DHEA, and androstenedione

> relative to LabCorp's age- and sex-specific

> reference range means.

>· Female patients with an ASD diagnosis had

> significantly higher relative testosterone

> and free testosterone levels than the male

> patients.

>· Elevations in male hormone levels may result

> from environmental exposures, such as mercury,

> and increase the toxicity of the exposure.

>

>The results of the present study confirm and

>extend previous observations, establishing the

>clinical importance of elevated male-hormone

>levels in those diagnosed with an ASD. Also,

>this paper's findings are consistent with those

>observed by many others who treat similar

>patients.

>

>The researchers also found that administration

>of a male-hormone-reducing drug (leuprolide

>acetate, LUPRON®) to nearly 200 patients

>diagnosed with an ASD resulted in significantly

>lowered male-hormone levels and corresponding

>clinically significant reductions in

>hyperactivity/impulsivity, stereotypy,

>aggression, self injury, abnormal sexual

>behaviors, and/or irritability behaviors that

>frequently occur in patients with an ASD, with

>few non-responders and minimal adverse effects

>from the therapy.

>

>Thus, hormone testing is being successfully

>used to:

>· Demonstrate the role of elevated male

> hormones in populations with an ASD,

>· Clinically identify children and adults

> who have elevated male hormones, and

>· Track male hormone levels from affected

> patients undergoing treatment to lower

> male hormones.

>

>Today, any parent, physician, or healthcare

>provider can easily confirm whether a

>patient diagnosed with an ASD has elevated

>male hormones through testing done at LabCorp.

>

>Among other articles, the CoMeD's website,

>http://www.Mercury-freeDrugs.org, contains

>full copies of the 2006 and 2007 papers

>authored by A. Geier and Mark R. Geier.

>

Anyone wishing to post this draft to

their group or to others has my

permission to do so PROVIDED you

do not alter the document sent to you

in any manner.

Hopefully, this e-mail will alert you

to visit the CoMeD website:

http://www.mercury-freedrugs.org

after 3 Dec 2007 to view this document and

any others that have been posted since

the last time you visited.

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Respectfully,

Dr. King

http://www.dr-king.com

Founder of FAME Systems and Science Advisor

to CoMeD