A very short and sanitised summary of vaccine ingredients.

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Appendix ASummary of Contents ofVaccines Licensed in the U.S.In addition to identifying specific substances that contraindicate certain vaccines (shown under the category "Allergies" on the Symptom or Condition chart), the ACIP also makes the more general statement that a "serious allergic reaction [e.g., anaphylaxis] to a vaccine component" is a contraindication.The following table summarizes excipients (i.e., inert substances added as a vehicle) contained in vaccines licensed in the United States. While these substances, except as noted above, are not specified by the ACIP as contraindications to vaccination, providers should be aware of substances contained in vaccines should they encounter a

patient with a known anaphylactic allergy. Vaccine Contains Anthrax (BioThrax) Aluminum hydroxide, Benzethonium chloride, Formaldehyde or formalin, Sodium chloride BCG (Tice) Lactose, Sodium chloride DTaP (Daptacel) Aluminum phosphate, Formaldehyde or formalin, Sodium chloride, 2-phenoxyethanol DTaP (Infanrix) Formaldehyde or formalin, 2-phenoxyethanol, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Polysorbate 80, Sodium chloride DTap (Tripedia) Aluminum potassium sulfate, Formaldehyde or formalin, Gelatin, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Polysorbate 80, Sodium chloride, Thimerosal* DTap (Most brands) Hydrochloric acid DTaP/Hib (TriHIbit) Aluminum potassium sulfate, Formaldehyde or formalin, Gelatin, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium

dihydrogen phosphate), Polysorbate 80, Sodium chloride, Thimerosal*, Ammonium sulfate, Sucrose DTaP/HepB/IPV (Pediarix) 2-phenoxyethanol, Sodium chloride, Aluminum, Formaldehyde, Polysorbate 80, Thimerosal*, Neomycin, Polymyxin B, Yeast protein DT (Aventis) Aluminum potassium sulfate, Formaldehyde or formalin, Sodium chloride, Thimerosal DT (Massachusetts) Aluminum hydroxide, Formaldehyde or formalin, Sodium chloride, Thimerosal DT (Some brands) Glycine, Hydrochloric acid, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Sodium acetate, Sodium hydroxide Hib (ACTHib) Ammonium sulfate, Formaldehyde or formalin, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Sodium chloride, Sucrose Hib (PedvaxHib) Aluminum hydroxide, Sodium chloride Hib (HibTITER) Yeast protein, Thimerosal (multi-dose) Hib (Some packages) Lactose Hib/HepB (Comvax) Aluminum hydroxide, Sodium borate, Sodium chloride, Yeast protein Hep A (Havrix) Aluminum hydroxide, Amino acids, Bovine albumin or serum, Formaldehyde or formalin, MRC-5 cellular protein, 2-phenoxyethanol, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Polysorbate 20, Sodium chloride Hep A (Vaqta) Aluminum hydroxide, Bovine albumin or serum, DNA, Formaldehyde or formalin, MRC-5 cellular protein, Sodium borate, Sodium chloride Hep

B (Engerix- Aluminum hydroxide, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Sodium chloride, Yeast protein, Thimerosal* Hep B (Recombivax) Aluminum hydroxide, Sodium chloride, Yeast protein HepA/HepB (Twinrix) Phosphate-buffer sodium chloride, Alunimum Phosphate, Aluminum hydroxide, 2-phenoxyethanol, Amino acids, Polysorbate 20, Formalin, Thimerosal*, Yeast protein, Neomycin sulfate Influenza (Fluvirin) Beta-propiolactone, Egg protein, Neomycin, Polymyxin B, Polyoxyethylene 9-10 nonyl

phenol (Triton N-101, octoxynol 9), Sodium chloride, Thimerosal Influenza (Fluzone) Egg protein, Formaldehyde or formalin, Gelatin, Polyethylene glycol p-isooctylphenyl ether (Triton X-100), Sodium chloride, Thimerosal Influenza (Flumist) Egg protein, Gentamicin, Monosodium glutamate, Sucrose, Potassium phosphate Influenza (Varies) Bactopeptone IPV (Ipol) Formaldehyde or formalin, Neomycin, 2-phenoxyethanol, Phosphate buffers (e.g., disodium,

monosodium, potassium, sodium dihydrogen phosphate), Polymyxin B, Sodium chloride, Streptomycin Japanese Encephalitis (JE-Vax) Formaldehyde or formalin, Gelatin, Mouse serum protein Measles (Attenuvax) Gelatin, Neomycin, Sorbitol Meningococcal (Menomune) Lactose, Thimerosal* Mumps (Mumpsvax) Gelatin, Neomycin, Sorbitol MMR (MMR-II) Gelatin, Neomycin, Sorbitol Pneumococcal (Pneumovax) Phenol, Sodium chloride Pneumococcal (Prevnar) Aluminum phosphate, Sodium chloride Rabies (BioRab) Aluminum phosphate, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Thimerosal Rabies (Imovax) Beta-propiolactone, Bovine albumin or serum, Human serum albumin, MRC-5 cellular protein, Neomycin, Phenol red (phenolsulfonphthalein), Sodium

chloride, Vitamins (unspecified) Rabies (RabAvert) Amphotericin B, Beta-propiolactone, Bovine albumin or serum, Chlortetracycline, Ethylenediamine-tetraacetic acid sodium (EDTA), Gelatin, MRC-5 cellular protein, Neomycin, Ovalbumin, Potassium glutamate, Sodium chloride Rubella (Meruvax II) Gelatin, Neomycin, Sorbitol Td (Aventis) Aluminum potassium sulfate, Formaldehyde or formalin, Sodium chloride, Thimerosal, (may contain Glycine, Sodium acetate, Sodium hydroxide) Td (Massachusetts) Aluminum hydroxide, Aluminum Phosphate, Formaldehyde or formalin, Sodium chloride, Thimerosal, (may contain Glycine, Sodium acetate, Sodium hydroxide) Typhoid (inactivated - Typhim Vi) Phenol, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Polydimethylsilozone, sodium chloride Typhoid (oral - TY21a) Amino acids, Ascorbic acid, Gelatin, Lactose, Magnesium stearate, Sucrose Vaccinia (DryVax) Bovine albumin or serum, Brilliant green, Chlortetracycline, Glycerin, Neomycin, Phenol, Polymyxin B,

Streptomycin Varicella (Varivax) Bovine albumin or serum, Ethylenediamine-tetraacetic acid sodium (EDTA), Gelatin, Monosodium glutamate, MRC-5 cellular protein, Neomycin, Phosphate buffers (e.g., disodium, monosodium, potassium, sodium dihydrogen phosphate), Sodium chloride, Sucrose Yellow Fever (YF-Vax) Egg protein, Gelatin, Sodium chloride, Sorbitol *Whenever "thimerosal" is marked with an asterisk (*) it indicates that the product should be considered equivalent to thimerosal-free products. This vaccine may contain trace amounts (<3 mcg) of mercury left after post-production thimerosal removal, but these amounts have no

biological effect. JAMA 1999;282(18) and JAMA 2000;283(16). All reasonable efforts have been made to assure the accuracy of this information, but manufacturers may change product contents. If in doubt, check the appropriate package insert. Information in this appendix was adapted primarily from:Grabenstein JD. ImmunoFacts: Vaccines & Immunologic Drugs. St. Louis:Facts and Comparisons, August 2002 http://www.cdc.gov/nip/recs/contraindications.htm "Our ideal is not the spirituality that withdraws from life but the

conquest of life by the power of the spirit." - Aurobindo.

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