Re: Old Man Displaces Refrigerator Mother Theory of Autism Etiology

[Guest guest]

Fragile X? No "twisty" Y.

"Old Man" Displaces "Refrigerator Mother" Theory of Autism Etiology

"The study "provides the first convincing evidence that advanced paternal age is a risk factor for autism spectrum disorder," said the authors from Mount Sinai School of Medicine, New York, and the Institute of Psychiatry, King's College London."http://www.theage.com.au/news/world/autism-risk-linked-to-older-fathers--study/2006/09/05/1157222077908.htmlAutism risk linked to older fathers - studyEmailPrintNormal fontLarge fontChicagoSeptember 5, 2006 - 12:50AMAdvertisementAdvertisementChildren fathered by men at age 40 and older have a higher risk of developing autism, possibly because of mutations or other genetic changes, according to new research.The study "provides the first convincing evidence that advanced paternal age is a risk factor for autism spectrum disorder," said the authors from Mount Sinai School of Medicine, New York, and the Institute of Psychiatry, King's College London.The findings were based on a look at thousands of children born in Israel during the 1980s. All males and three-fourths of the females born in the time period involved were checked by Israeli draft officials at age 17 and any psychiatric disorders were recorded."Offspring of men 40 years or older were 5.75 times more likely to have (autism disorders) compared with offspring of men younger than 30 years," said the study published in the Archives of General Psychiatry."Advancing maternal age showed no association," it added.Autism can cause symptoms ranging from social isolation to repetitive and damaging behaviours and sometimes mental retardation.The problem has become increasingly common, affecting 50 in every 10,000 children in the United States, in part due to greater awareness and changes in diagnoses, the study said.The report said several genetic mechanisms might be behind the paternal age association found, including spontaneous mutations in sperm-producing cells.

[Guest guest]

Crap. My dh was 38 when the last

kid was born. I guess my kid isn’t autistic after all!! woopie!

From: EOHarm [mailto:EOHarm ] On Behalf Of J. Krakow

Sent: Monday, September 04, 2006

3:17 PM

EOHarm

Subject: " Old

Man " Displaces " Refrigerator Mother " Theory of Autism Etiology

" The study " provides the first convincing evidence that

advanced paternal age is a risk factor for autism spectrum disorder, " said

the authors from Mount Sinai School of Medicine, New York, and the Institute of Psychiatry, King's College London. "

http://www.theage.com.au/news/world/autism-risk-linked-to-older-fathers--study/2006/09/05/1157222077908.html

Autism risk linked to older fathers - study

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Children fathered by men at age 40 and older have a

higher risk of developing autism, possibly because of mutations or other

genetic changes, according to new research.

The study " provides the first convincing evidence that advanced paternal

age is a risk factor for autism spectrum disorder, " said the authors from

Mount Sinai School of Medicine, New York, and the Institute of Psychiatry,

King's College London.

The findings were based on a look at thousands of children born in Israel during

the 1980s. All males and three-fourths of the females born in the time period

involved were checked by Israeli draft officials at age 17 and any psychiatric

disorders were recorded.

" Offspring of men 40 years or older were 5.75 times more likely to have

(autism disorders) compared with offspring of men younger than 30 years, "

said the study published in the Archives of General Psychiatry.

" Advancing maternal age showed no association, " it added.

Autism can cause symptoms ranging from social isolation to repetitive and damaging

behaviours and sometimes mental retardation.

The problem has become increasingly common, affecting 50 in every 10,000

children in the United

States, in part due to greater awareness and

changes in diagnoses, the study said.

The report said several genetic mechanisms might be behind the paternal age

association found, including spontaneous mutations in sperm-producing cells.

[Guest guest]

Not in our case....birthfather was 18 yrs.old.

--- " J. Krakow " <rkrakow@...> wrote:

> " The study " provides the first convincing evidence

> that advanced

> paternal age is a risk factor for autism spectrum

> disorder, " said the

> authors from Mount Sinai School of Medicine, New

> York, and the

> Institute of Psychiatry, King's College London. "

>

>

>

http://www.theage.com.au/news/world/autism-risk-linked-to-older-

>

> fathers--study/2006/09/05/1157222077908.html

> Autism risk linked to older fathers - study

> Email

> Print

> Normal font

> Large font

> Chicago

> September 5, 2006 - 12:50AM

> AdvertisementAdvertisement

>

>

> Children fathered by men at age 40 and older have a

> higher risk of

> developing autism, possibly because of mutations or

> other genetic

> changes, according to new research.

>

> The study " provides the first convincing evidence

> that advanced

> paternal age is a risk factor for autism spectrum

> disorder, " said the

> authors from Mount Sinai School of Medicine, New

> York, and the

> Institute of Psychiatry, King's College London.

>

> The findings were based on a look at thousands of

> children born in

> Israel during the 1980s. All males and three-fourths

> of the females

> born in the time period involved were checked by

> Israeli draft

> officials at age 17 and any psychiatric disorders

> were recorded.

>

> " Offspring of men 40 years or older were 5.75 times

> more likely to have

> (autism disorders) compared with offspring of men

> younger than 30

> years, " said the study published in the Archives of

> General Psychiatry.

>

> " Advancing maternal age showed no association, " it

> added.

>

> Autism can cause symptoms ranging from social

> isolation to repetitive

> and damaging behaviours and sometimes mental

> retardation.

>

> The problem has become increasingly common,

> affecting 50 in every

> 10,000 children in the United States, in part due to

> greater awareness

> and changes in diagnoses, the study said.

>

> The report said several genetic mechanisms might be

> behind the paternal

> age association found, including spontaneous

> mutations in

> sperm-producing cells.

>

__________________________________________________

[Guest guest]

here's a stupid question- do older men have more metals in them?

[Guest guest]

You may remember this study published last year in the American

Journal of Epidemiology.

Of particular importance -

" Analyses showed no statistically significant association between

risk of autism and weight for gestational age, parity, number of

antenatal visits, parental age, or socioeconomic status. "

________

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search & DB=pubmed

Abstract

Am J Epidemiol. 2005 May 15;161(10):916-25; discussion 926-8.

Risk factors for autism: perinatal factors, parental psychiatric

history, and socioeconomic status.Larsson HJ, Eaton WW, Madsen KM,

Vestergaard M, Olesen AV, Agerbo E, Schendel D, Thorsen P, Mortensen

PB.

North Atlantic Neuro-Epidemiology Alliances, Department of

Epidemiology and Social Medicine, University of Aarhus, Aarhus,

Denmark.

Research suggests that heredity and early fetal development play a

causal role in autism. This case-control study explored the

association between perinatal factors, parental psychiatric history,

socioeconomic status, and risk of autism. The study was nested

within a cohort of all children born in Denmark after 1972 and at

risk of being diagnosed with autism until December 1999.

Prospectively recorded data were obtained from nationwide registries

in Denmark. Cases totaled 698 children with a diagnosis of autism;

each case was individually matched by gender, birth year, and age to

25 controls. Analyses by conditional logistic regression produced

risk ratios and 95% confidence intervals. Adjusted analyses showed

that the risk of autism was associated with breech presentation

(risk ratio (RR) = 1.63, 95% confidence interval (CI): 1.18, 2.26),

low Apgar score at 5 minutes (RR = 1.89, 95% CI: 1.10, 3.27),

gestational age at birth <35 weeks (RR = 2.45, 95% CI: 1.55, 3.86),

and parental psychiatric history (schizophrenia-like psychosis: RR =

3.44, 95% CI: 1.48, 7.95; affective disorder: RR = 2.91, 95% CI:

1.65, 5.14). Analyses showed no statistically significant

association between risk of autism and weight for gestational age,

parity, number of antenatal visits, parental age, or socioeconomic

status. Results suggest that prenatal environmental factors and

parental psychopathology are associated with the risk of autism.

These factors seem to act independently

______

Related article -

Pregnancy factors, parental psychiatric history, and preterm

delivery may be associated with the risk of autism

New-Medical.Net

23-May-2005

" Pregnancy factors, parental psychiatric history, and preterm

delivery may be associated with the risk of autism, according to a

recent study supported in part by the Centers for Disease Control

and Prevention (CDC). The study, " Risk Factors for Autism: Perinatal

Factors, Parental Psychiatric History, and Socioeconomic Status, "

appears in the most recent issue of the American Journal of

Epidemiology. "

http://www.news-medical.net/?id=10305

______

>

> " The study " provides the first convincing evidence that advanced

> paternal age is a risk factor for autism spectrum disorder, " said

the authors from Mount Sinai School of Medicine, New York, and the

> Institute of Psychiatry, King's College London. "

>

>

> http://www.theage.com.au/news/world/autism-risk-linked-to-older-

> fathers--study/2006/09/05/1157222077908.html

> Autism risk linked to older fathers - study

[Guest guest]

as silly as this is-this study-we could take our own vote on EOH-bet we come up with something different-my grandson's father was 25 when Josh was born.ianpsmom <ianpsmom@...> wrote: You may remember this study published last year in the American Journal of Epidemiology.Of particular importance - "Analyses showed no statistically significant association between risk of autism and weight for gestational age, parity, number of antenatal visits, parental age, or socioeconomic

status."________http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search & DB=pubmedAbstractAm J Epidemiol. 2005 May 15;161(10):916-25; discussion 926-8. Risk factors for autism: perinatal factors, parental psychiatric history, and socioeconomic status.Larsson HJ, Eaton WW, Madsen KM, Vestergaard M, Olesen AV, Agerbo E, Schendel D, Thorsen P, Mortensen PB. North Atlantic Neuro-Epidemiology Alliances, Department of Epidemiology and Social Medicine, University of Aarhus, Aarhus, Denmark.Research suggests that heredity and early fetal development play a causal role in autism. This case-control study explored the association between perinatal factors, parental psychiatric history, socioeconomic status, and risk of autism. The study was nested within a cohort of all

children born in Denmark after 1972 and at risk of being diagnosed with autism until December 1999. Prospectively recorded data were obtained from nationwide registries in Denmark. Cases totaled 698 children with a diagnosis of autism; each case was individually matched by gender, birth year, and age to 25 controls. Analyses by conditional logistic regression produced risk ratios and 95% confidence intervals. Adjusted analyses showed that the risk of autism was associated with breech presentation (risk ratio (RR) = 1.63, 95% confidence interval (CI): 1.18, 2.26), low Apgar score at 5 minutes (RR = 1.89, 95% CI: 1.10, 3.27), gestational age at birth <35 weeks (RR = 2.45, 95% CI: 1.55, 3.86), and parental psychiatric history (schizophrenia-like psychosis: RR = 3.44, 95% CI: 1.48, 7.95; affective disorder: RR = 2.91, 95% CI: 1.65, 5.14). Analyses showed no statistically significant association between risk of

autism and weight for gestational age, parity, number of antenatal visits, parental age, or socioeconomic status. Results suggest that prenatal environmental factors and parental psychopathology are associated with the risk of autism. These factors seem to act independently______Related article -Pregnancy factors, parental psychiatric history, and preterm delivery may be associated with the risk of autism New-Medical.Net23-May-2005 "Pregnancy factors, parental psychiatric history, and preterm delivery may be associated with the risk of autism, according to a recent study supported in part by the Centers for Disease Control and Prevention (CDC). The study, "Risk Factors for Autism: Perinatal Factors, Parental Psychiatric History, and Socioeconomic Status," appears in the most recent issue of the American Journal of Epidemiology." http://www.news-medical.net/?id=10305______--- In EOHarm , " J. Krakow" <rkrakow@...> wrote:>> "The study "provides the first convincing evidence that advanced > paternal age is a risk factor for autism spectrum disorder," said the authors from Mount Sinai School of Medicine, New York, and the > Institute of Psychiatry, King's College London."> > > http://www.theage.com.au/news/world/autism-risk-linked-to-older- > fathers--study/2006/09/05/1157222077908.html> Autism risk linked to older fathers - study

Messenger with Voice. Make PC-to-Phone Calls to the US (and 30+ countries) for 2¢/min or less.

[Guest guest]

That is far from a stupid question - it is a very interesting one.

Research on brains (of Greenlanders and Danes) published in 1999 showed

that mercury accumulation is age dependent . The study found that the

mercury exposure was primarily methylmercury and slowly transformed to

inorganic mercury. The mercury accumulated primarily in glial cells.

Interesting in that ethylmercury has been shown to dealkylate or

demethylate more quickly into inorganic than methylmercury - also

suspected of accumulating in glia.

On Sep 4, 2006, at 7:20 PM, christine@... wrote:

> here's a stupid question- do older men have more metals in them?

>

>

>

>

J. Krakow

Attorney At Law

2001 Marcus Avenue, Suite N125

Lake Success, New York 11042

(516) 354-3300

(646) 349-1771 (fax)

(212) 227-0600 (NYC telephone)

[Guest guest]

I agree stupid studies are done when research money is thrown out like

candy. That said, studying the age of parents isn't necessarily a

stupid study. Aging is a factor in Down Syndrome, so it's not crazy to

consider age for other offspring issues. Could it be that the older

parents are, the less likely the offspring will be able to excrete

heavy metals or figh off immune system assaults, like with vaccines?

Debi

[Guest guest]

Could it also be, that older parents have more mercury and/or other heavy metal burdens to pass on to their children? I can't recall whose study I read a few months ago, but it was mentioned there that the heavier one's mercury burden, the harder it becomes for the body to excrete the mercury. AasaDebi <fightingautism@...> wrote: I agree stupid studies are done when research money is thrown out like candy. That said, studying the age of parents isn't necessarily a stupid

study. Aging is a factor in Down Syndrome, so it's not crazy to consider age for other offspring issues. Could it be that the older parents are, the less likely the offspring will be able to excrete heavy metals or figh off immune system assaults, like with vaccines?Debi

[Guest guest]

Could it also be, that older parents have more mercury and/or other heavy metal burdens to pass on to their children? I can't recall whose study I read a few months ago, but it was mentioned there that the heavier one's mercury burden, the harder it becomes for the body to excrete the mercury. AasaDebi <fightingautism@...> wrote: I agree stupid studies are done when research money is thrown out like candy. That said, studying the age of parents isn't necessarily a stupid

study. Aging is a factor in Down Syndrome, so it's not crazy to consider age for other offspring issues. Could it be that the older parents are, the less likely the offspring will be able to excrete heavy metals or figh off immune system assaults, like with vaccines?Debi

[Guest guest]

Older and bigger fish have more metals in them too, than younger and smaller fish do. That has been known for years... Aasa"christine@..." <christine@...> wrote: here's a stupid question- do older men have more metals in them?

[Guest guest]

Older and bigger fish have more metals in them too, than younger and smaller fish do. That has been known for years... Aasa"christine@..." <christine@...> wrote: here's a stupid question- do older men have more metals in them?

[Guest guest]

on 9/4/06 7:55 PM, Debi at fightingautism@... wrote:

I agree stupid studies are done when research money is thrown out like

candy. That said, studying the age of parents isn't necessarily a

stupid study. Aging is a factor in Down Syndrome, so it's not crazy to

consider age for other offspring issues. Could it be that the older

parents are, the less likely the offspring will be able to excrete

heavy metals or figh off immune system assaults, like with vaccines?

Debi

I guess what I meant about a " stupid question " is I was questioning this study. It's like " children with autism have bigger brains- so bigger brains MUST cause autism " .... well maybe they have mercury poisoning-which results in bigger brains. I just get so frustrated with the A+B=D crap. They aren't looking at the whole picture. The study may not be " stupid " , but making conclusions is irresponsible. I'm not a doctor or researcher, but I look at this stuff and think " is this what we need to be spending our money on? " . (i know- preaching to the choir here) And people wonder why we get annoyed at NAAR/AS sometimes. Also, it could mean that older parents may be more responsible and have more money- and vaccinate their children more. argh....

Happy Labor Day everyone-

[Guest guest]

on 9/4/06 7:55 PM, Debi at fightingautism@... wrote:

I agree stupid studies are done when research money is thrown out like

candy. That said, studying the age of parents isn't necessarily a

stupid study. Aging is a factor in Down Syndrome, so it's not crazy to

consider age for other offspring issues. Could it be that the older

parents are, the less likely the offspring will be able to excrete

heavy metals or figh off immune system assaults, like with vaccines?

Debi

I guess what I meant about a " stupid question " is I was questioning this study. It's like " children with autism have bigger brains- so bigger brains MUST cause autism " .... well maybe they have mercury poisoning-which results in bigger brains. I just get so frustrated with the A+B=D crap. They aren't looking at the whole picture. The study may not be " stupid " , but making conclusions is irresponsible. I'm not a doctor or researcher, but I look at this stuff and think " is this what we need to be spending our money on? " . (i know- preaching to the choir here) And people wonder why we get annoyed at NAAR/AS sometimes. Also, it could mean that older parents may be more responsible and have more money- and vaccinate their children more. argh....

Happy Labor Day everyone-

[Guest guest]

The " evidence " may show that older men tend to have better

insurance, so the child gets full, on time vaccinations.

Carolyn

>

> " The study " provides the first convincing evidence that advanced

> paternal age is a risk factor for autism spectrum disorder, " said

the

> authors from Mount Sinai School of Medicine, New York, and the

> Institute of Psychiatry, King's College London. "

>

>

> http://www.theage.com.au/news/world/autism-risk-linked-to-older-

> fathers--study/2006/09/05/1157222077908.html

> Autism risk linked to older fathers - study

> Email

> Print

> Normal font

> Large font

> Chicago

> September 5, 2006 - 12:50AM

> AdvertisementAdvertisement

>

>

> Children fathered by men at age 40 and older have a higher risk

of

> developing autism, possibly because of mutations or other genetic

> changes, according to new research.

>

> The study " provides the first convincing evidence that advanced

> paternal age is a risk factor for autism spectrum disorder, " said

the

> authors from Mount Sinai School of Medicine, New York, and the

> Institute of Psychiatry, King's College London.

>

> The findings were based on a look at thousands of children born

in

> Israel during the 1980s. All males and three-fourths of the

females

> born in the time period involved were checked by Israeli draft

> officials at age 17 and any psychiatric disorders were recorded.

>

> " Offspring of men 40 years or older were 5.75 times more likely to

have

> (autism disorders) compared with offspring of men younger than 30

> years, " said the study published in the Archives of General

Psychiatry.

>

> " Advancing maternal age showed no association, " it added.

>

> Autism can cause symptoms ranging from social isolation to

repetitive

> and damaging behaviours and sometimes mental retardation.

>

> The problem has become increasingly common, affecting 50 in every

> 10,000 children in the United States, in part due to greater

awareness

> and changes in diagnoses, the study said.

>

> The report said several genetic mechanisms might be behind the

paternal

> age association found, including spontaneous mutations in

> sperm-producing cells.

>

[Guest guest]



Mercury, as a bioaccumulator, would be expected in higher concentrations in older men. Just as older fish, and fish higher on the trophic order (carnivoves vs. plankton eaters) would also be expected to bioaccumulate mercury.

Re: "Old Man" Displaces "Refrigerator Mother" Theory of Autism Etiology

That is far from a stupid question - it is a very interesting one. Research on brains (of Greenlanders and Danes) published in 1999 showed that mercury accumulation is age dependent . The study found that the mercury exposure was primarily methylmercury and slowly transformed to inorganic mercury. The mercury accumulated primarily in glial cells.Interesting in that ethylmercury has been shown to dealkylate or demethylate more quickly into inorganic than methylmercury - also suspected of accumulating in glia.On Sep 4, 2006, at 7:20 PM, christine@... wrote:

here's a stupid question- do older men have more metals in them? J. KrakowAttorney At Law2001 Marcus Avenue, Suite N125Lake Success, New York 11042(516) 354-3300 (646) 349-1771 (fax)(212) 227-0600 (NYC telephone)

[Guest guest]

Far from a joke, we know that vaccinations cause autism. ]

So, any theory which posits a connection to vaccinations is on the table.

Your theory is actually more valid than what the government pays for- because your theory, even as a joke, is much closer to reality, than the Emperor's New Clothes research presently being done.

Re: "Old Man" Displaces "Refrigerator Mother" Theory of Autism Etiology

The "evidence" may show that older men tend to have better insurance, so the child gets full, on time vaccinations.Carolyn>> "The study "provides the first convincing evidence that advanced > paternal age is a risk factor for autism spectrum disorder," said the > authors from Mount Sinai School of Medicine, New York, and the > Institute of Psychiatry, King's College London."> > > http://www.theage.com.au/news/world/autism-risk-linked-to-older- > fathers--study/2006/09/05/1157222077908.html> Autism risk linked to older fathers - study> Email> Print> Normal font> Large font> Chicago> September 5, 2006 - 12:50AM> AdvertisementAdvertisement> > > Children fathered by men at age 40 and older have a higher risk of > developing autism, possibly because of mutations or other genetic > changes, according to new research.> > The study "provides the first convincing evidence that advanced > paternal age is a risk factor for autism spectrum disorder," said the > authors from Mount Sinai School of Medicine, New York, and the > Institute of Psychiatry, King's College London.> > The findings were based on a look at thousands of children born in > Israel during the 1980s. All males and three-fourths of the females > born in the time period involved were checked by Israeli draft > officials at age 17 and any psychiatric disorders were recorded.> > "Offspring of men 40 years or older were 5.75 times more likely to have > (autism disorders) compared with offspring of men younger than 30 > years," said the study published in the Archives of General Psychiatry.> > "Advancing maternal age showed no association," it added.> > Autism can cause symptoms ranging from social isolation to repetitive > and damaging behaviours and sometimes mental retardation.> > The problem has become increasingly common, affecting 50 in every > 10,000 children in the United States, in part due to greater awareness > and changes in diagnoses, the study said.> > The report said several genetic mechanisms might be behind the paternal > age association found, including spontaneous mutations in > sperm-producing cells.>

[Guest guest]

Who were the authors?HHF "Old Man" Displaces "Refrigerator Mother" Theory of Autism Etiology"The study "provides the first convincing evidence that advanced paternal age is a risk factor for autism spectrum disorder," said the authors from Mount Sinai School of Medicine, New York, and the Institute of Psychiatry, King's College London."http://www.theage.com.au/news/world/autism-risk-linked-to-older-fathers--study/2006/09/05/1157222077908.htmlAutism risk linked to older fathers - studyEmailPrintNormal fontLarge fontChicagoSeptember 5, 2006 - 12:50AMAdvertisementAdvertisementChildren fathered by men at age 40 and older have a higher risk of developing autism, possibly because of mutations or other genetic changes, according to new research.The study "provides the first convincing evidence that advanced paternal age is a risk factor for autism spectrum disorder," said the authors from Mount Sinai School of Medicine, New York, and the Institute of Psychiatry, King's College London.The findings were based on a look at thousands of children born in Israel during the 1980s. All males and three-fourths of the females born in the time period involved were checked by Israeli draft officials at age 17 and any psychiatric disorders were recorded."Offspring of men 40 years or older were 5.75 times more likely to have (autism disorders) compared with offspring of men younger than 30 years," said the study published in the Archives of General Psychiatry."Advancing maternal age showed no association," it added.Autism can cause symptoms ranging from social isolation to repetitive and damaging behaviours and sometimes mental retardation.The problem has become increasingly common, affecting 50 in every 10,000 children in the United States, in part due to greater awareness and changes in diagnoses, the study said.The report said several genetic mechanisms might be behind the paternal age association found, including spontaneous mutations in sperm-producing cells.

[Guest guest]

I wasn't joking. And, I do agree about the Emperor's new clothes.

C

> >

> > " The study " provides the first convincing evidence that

advanced

> > paternal age is a risk factor for autism spectrum disorder, "

said

> the

> > authors from Mount Sinai School of Medicine, New York, and the

> > Institute of Psychiatry, King's College London. "

> >

> >

> > http://www.theage.com.au/news/world/autism-risk-linked-to-

older-

> > fathers--study/2006/09/05/1157222077908.html

> > Autism risk linked to older fathers - study

> > Email

> > Print

> > Normal font

> > Large font

> > Chicago

> > September 5, 2006 - 12:50AM

> > AdvertisementAdvertisement

> >

> >

> > Children fathered by men at age 40 and older have a higher

risk

> of

> > developing autism, possibly because of mutations or other

genetic

> > changes, according to new research.

> >

> > The study " provides the first convincing evidence that

advanced

> > paternal age is a risk factor for autism spectrum disorder, "

said

> the

> > authors from Mount Sinai School of Medicine, New York, and the

> > Institute of Psychiatry, King's College London.

> >

> > The findings were based on a look at thousands of children

born

> in

> > Israel during the 1980s. All males and three-fourths of the

> females

> > born in the time period involved were checked by Israeli draft

> > officials at age 17 and any psychiatric disorders were

recorded.

> >

> > " Offspring of men 40 years or older were 5.75 times more

likely to

> have

> > (autism disorders) compared with offspring of men younger than

30

> > years, " said the study published in the Archives of General

> Psychiatry.

> >

> > " Advancing maternal age showed no association, " it added.

> >

> > Autism can cause symptoms ranging from social isolation to

> repetitive

> > and damaging behaviours and sometimes mental retardation.

> >

> > The problem has become increasingly common, affecting 50 in

every

> > 10,000 children in the United States, in part due to greater

> awareness

> > and changes in diagnoses, the study said.

> >

> > The report said several genetic mechanisms might be behind the

> paternal

> > age association found, including spontaneous mutations in

> > sperm-producing cells.

> >

>

[Guest guest]

Sorry about that. In retrospect, you're absolutely right.

Maybe they should hire you to do their research.

I don't know my history well and I may be mixing metaphors, but didn't someone say:

"The last refuge of a scoundrel is the autism gene."?

Re: "Old Man" Displaces "Refrigerator Mother" Theory of Autism Etiology

I wasn't joking. And, I do agree about the Emperor's new clothes.C> >> > "The study "provides the first convincing evidence that advanced > > paternal age is a risk factor for autism spectrum disorder," said > the > > authors from Mount Sinai School of Medicine, New York, and the > > Institute of Psychiatry, King's College London."> > > > > > http://www.theage.com.au/news/world/autism-risk-linked-to-older- > > fathers--study/2006/09/05/1157222077908.html> > Autism risk linked to older fathers - study> > Email> > Print> > Normal font> > Large font> > Chicago> > September 5, 2006 - 12:50AM> > AdvertisementAdvertisement> > > > > > Children fathered by men at age 40 and older have a higher risk > of > > developing autism, possibly because of mutations or other genetic > > changes, according to new research.> > > > The study "provides the first convincing evidence that advanced > > paternal age is a risk factor for autism spectrum disorder," said > the > > authors from Mount Sinai School of Medicine, New York, and the > > Institute of Psychiatry, King's College London.> > > > The findings were based on a look at thousands of children born > in > > Israel during the 1980s. All males and three-fourths of the > females > > born in the time period involved were checked by Israeli draft > > officials at age 17 and any psychiatric disorders were recorded.> > > > "Offspring of men 40 years or older were 5.75 times more likely to > have > > (autism disorders) compared with offspring of men younger than 30 > > years," said the study published in the Archives of General > Psychiatry.> > > > "Advancing maternal age showed no association," it added.> > > > Autism can cause symptoms ranging from social isolation to > repetitive > > and damaging behaviours and sometimes mental retardation.> > > > The problem has become increasingly common, affecting 50 in every > > 10,000 children in the United States, in part due to greater > awareness > > and changes in diagnoses, the study said.> > > > The report said several genetic mechanisms might be behind the > paternal > > age association found, including spontaneous mutations in > > sperm-producing cells.> >>