Guest guest Posted September 18, 2003 Report Share Posted September 18, 2003 If you see from the article Suze posted given in the first study that there was no dose-response between animal fat and cancer that random results can throw off results, especially if you decide how to define your groups after you collect the data (which of course you would do). Interestingly, if the study had split the " quintiles " up differently, or into different sized groups, the relationship could have disappeared. If you notice, the groups aren't equivalent in number of people, span of median fat intake, or span of total fat percentage intake. Giving the last " quintile " the folks with the very low incidence of cancer gives the opportunity to see more folks in the middle, which had a very low total span of fat intake, who perhaps by chance had more cancer. If the groups were spread out more, broken into more groups, or arranged in different ways, folks from the middle could have gotten included with folks or some folks from the end, and the linear increase that's seen in the middle would have disappeared. I have an anecdote about this. Last lab in my biology class we did an experiment to see if athletes have healthier hearts. Each of us formed a group of 3-4 people, two who were to be subjects, one who was to be designated an " athlete " and the other a " non-athlete. " All the subjects did a stepping exercise in rhythmic unison for 3 minutes. Pulses were measured before, after, and every minute after and recorded. The data was organized for starting pulse, pulse after exercise, and recovery time (when pulse returned to initial pulse. I was at first going to designate myself an athlete, becuase I borderline fit her definition (basically regular exercise or training of some kind, not necessarily organized.) But the guy I ended up with played organized basketball and trained regularly, so we put him in the athlete group and me in the non-athlete group. There ended up being a girl in each group for the final data (i.e. athlete and non-athlete), both of whom had tremendously lower pulse rates regardless athletic ability. In the final data, if you looked at the individual people (and there were only six subjects) there was NO correlation whatsoever between the athleticism of the person and the heart rate or recovery time. If you couldn't see this from looking at the chalk board you were blind as a bat (though only I seemed to notice or care). However, since my pulse alone was *way* higher than anyones at starting, finishing, and recovery time (my pulse never actually recovered until after I stopped measuring it) for reasons talked about in the heart rate thread (probably unrelated to heart health), and I was thrown in the non-athlete category, I threw the averages up tremendously. In each group, there were people with almost identical starting finishing pulses and recovery time (I wish I had the data but it's gone), and the only correlation with anything was sex. So did the teacher take note? No, because she " knew " that the study was " supposed " to find a correlation, so she said, " ok, now everyone calculate the averages. " I objected. 'But there's one person out of six whose data is off the charts and will throw the averages off.' But we averaged it anyway, to get a deliberately less accurate result. Notice also that if we had three categories instead of two, -athelte- -nonathlete (or sedentary)- and something in the middle to describe me (regular personal exercise), then what the study would have found would be no difference between athletes and sedentary people, but people who get regular exercise but aren't athletes have much higher pulses. So how you define your groups and get your averages makes the entire difference in what your study " finds. " And of course, you always analyze and organize the data *after* you collect it. Chris Quote Link to comment Share on other sites More sharing options...
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