/was: Re: Speech probs and calcium

[Guest guest]

Hey ,

It's slightly complex. They no longer administer vitamin K3 --

menadiol -- at birth (it is now banned in the US by the FDA). They

give K1 (phylloquinone, marketed as phytonadione) to newborns -- 0.5

to 1 mg IM to prevent hypoprothrombinemia and intracranial

hemorrhage from birth trauma. The problem is that the administration

of K1 has been associated with neonatal jaundice resulting in severe

hemolytic anemia and even death in some newborns with genetic G6PD

deficiency - http://fn.bmjjournals.com/cgi/reprint/88/6/F534 , so

there are still some question marks about Vitamin K1 use in patinets

with genetic G6PD deficiency.

I am very interested in this subject because Lulu was given Vitamin

K1 at birth along with a Hep B shot with Thimerosal in it. She then

developed neonatal jaundice several days later, and at the end had

severe macrocytic anemia, which points to the possibility of

hemolysis from Vitamin K and a G6PD deficiency. She does bruise

easily, has broken capilaries and has had some excessive bleeding.

However, she seemed to respond fabulously to the Super K with K2 by

LEF, and that has 9 mgs of K1 in it. So I keep wondering if some

metabolically-induced G6PD deficiency is part of her picture -- I

don't think she has a genetic G6PD deficiency or we may have seen

much worse happen. Anyway, G6PD deficiency is not associated with

neurological problems, unless you have brain damage due to severe

hemolysis, etc -- these things do happen.

G6PDH is essential for many bodily processes, but one of them is to

produce NADH which is then used for glutathione recycling. She

responded fabulously to NADH, and she has had very low reduced

glutathione. Anyway, it's one more piece of the puzzle to keep watch

on for Lulu.

Hope this clarifies a little bit.

Hugs,

Theresa

> >

> > Sue,

> >

> > I did research this, and found that K1 and K2 present no

toxicity

> issues. Whatever is not used, I read, is excreted daily from the

> body, remarkable for a fat soluble vitamin, unlike A and D, but

not

> unlike Vitamin E, which has no toxicity even in doses as high as

> 10,000 IU per day.

> >

> > The thing to watch out for, I read is the K3, a synthethic K,

as

> it is toxic at too high of a dose.

> >

> > The dosage in the article is high, we don't use that much, but

use

> 9 mg of K1 and 1 mg of K2. K2 is thought to be the more

biologically

> active and is the K that everyone is supposed to produce in

their

> gut. I have just ordered 5 mg gel caps of K2 from Carlson

> laboratories and am going to try that.

> >

> > If you google K, you should find what I told you, if you find

> anything different, I would appreciate your sharing it.

> >

> > Good luck,

> >

> >

> > Re: Speech probs and

calcium

> >

> >

> > ---

> > > I was very intrigued by the article, and wondered about

> overdose

> > potential. I had no luck finding anything to indicate optimum

> > levels/dosages/indications of overdose. Also, it seemed that

in

> Uk it

> > has to be prescribed, so could be a problem to obtain. Does

> anyone

> > know anything about dosages, and overdose potential?

> > Sue

> >

>