Re: Genetic Testing Now Available via Jean Muscroft

[Guest guest]

In a message dated 28/09/2006 14:50:30 GMT Daylight Time, joanne@... writes:

Cost of this panel is £368

Hi Jo,

Do you think a lot of people will take this up when the actual yasko full panel is only (only, I say!!) $750 which I think is around £400... You see if you go staright to the horses mouth so to speak you have all the backing of Yasko-philes too dont you??

If it was half the price I would consider this route but with such a small difference, mmm, with the Yasko stuff you do get a book and DVD too remember...

Just a thought

Lotsa Love Caroline

xxx

PS I just worked out at todays exchange rate (Jeans test is $691, thats a lot compared to the $750, dont you think), when I had the Yasko done a coupla months ago it was $750, that may have changed, of course, JMHO....

[Guest guest]

Jo

Does Jean's panel also include an interpretation of results? I think

you have to pay extra for Dr Yasko to interpret the results (someone

will correct me if I am wrong here please?) and was wondering if this

is the same via Jean?

Thanks

Zoe

>

>

> In a message dated 28/09/2006 14:50:30 GMT Daylight Time,

> joanne@... writes:

>

> Cost of this panel is £368

>

>

> Hi Jo,

>

> Do you think a lot of people will take this up when the actual yasko

full

> panel is only (only, I say!!) $750 which I think is around £400...

You see if

> you go staright to the horses mouth so to speak you have all the

backing of

> Yasko-philes too dont you??

>

> If it was half the price I would consider this route but with such a

small

> difference, mmm, with the Yasko stuff you do get a book and DVD too

remember...

>

> Just a thought

> Lotsa Love Caroline

> xxx

>

> PS I just worked out at todays exchange rate (Jeans test is $691,

thats a

> lot compared to the $750, dont you think), when I had the Yasko done

a coupla

> months ago it was $750, that may have changed, of course, JMHO....

>

[Guest guest]

Thanks very much for this! I would love to get the ApoE and GST

testing done, so this is a possibility for the future for us. Too

bad there's no OTC or SOD -- these are the ones I would really love

to get my hands on -- other than G6PDH, DHPR and DHFR -- (LOL - I'm

such a science geek now -- who'd ever have thunk it?).

Can anyone tell me 1) how many SNPs and/or which SNPs Dr. Musgrove

will check for each gene and 2) if there is published information

(online, in a book, in other media) concerning the nutritional

interventions that will be recommended for these SNPs? Who has

determined what the nutrtional interventions are for each of these

mutations?

Thanks!

Best,

Theresa

Below is Dr. Yasko's current panel:

Complete Basic SNP Panel I

By looking at diagrammatic representations of the methylation

pathway we are able to draw a personalized map for each individual.

The methylation cycle is the ideal pathway to focus on for

nutrigenomic analysis because the proper function of this pathway is

essential for a number of critical reactions in the body.

Nutrigenomics integrates concepts in molecular biology and genomics

to study the ability of foods and nutritional supplements and how

these may assist in maintaining overall health and wellness.

According to the National Center of Excellence in Nutritional

Genomics at UC , " The science of nutrigenomics seeks to provide

a molecular understanding of how common dietary chemicals (i.e.,

nutrition) affect health by altering the expression and/or structure

of an individual's genetic makeup... by understanding our

nutritional needs, our nutritional status and our genotype,

nutrigenomics should enable individuals to manage better their

health and well being by precisely matching their diets with their

unique genetic makeup. "

Description for Multiple SNPs From Same Gene

ACAT - 1 SNP

ACE - 1 SNP

AHCY - 3 SNPs

BHMT - 4 SNPs

CBS - 4 SNPs

COMT - 4 SNPs

MAO A - 1 SNP

MTHFR - 3 SNP

MTR - 1 SNP

MTRR - 8 SNPs

NOS - 1 SNP

SUOX -1 SNPs

VDR - 3 SNPs

The description above is to help you make an informed decision when

considering the purchase of this test. The service provided does not

include an analysis of the test results. Any reference to analysis,

analysis of SNPs or SNP patterns refers to a service which is not

included in the cost and processing of this test.

*These statements have not been evaluated by the FDA. This product

is not intended to diagnose, cure or prevent disease. Always consult

with your professional health care provider before changing any

medication.

Price: $700.00

>

> Hi to all

>

> has now set up a panel of Genetic testing.

>

> You can see more info and explanation on Jeans Website and click

to

> see sample reports.

>

> This is a summary but you can click on this link to get to testing

> info page

>

> http://www.Autism and Aspergers Treatment.co.uk/genovations.htm

>

>

>

>

> Genovations Background

>

> With the decoding of nearly 40,000 genes in the human body,

patients

> can now benefit from a truly personalised health care approach.

>

> Genovations predictive genomic profile evaluates a carefully

> selective group of genetic variants in each patient providing a

> previously unseen glimpse into his or her potential health future.

>

> For more details read the Genovations Overview.

>

> I am now offering testing for the following SNPs:

>

> Jean's ASD SNPs Panel:

>

> Below are some of the most commonly found genetic weaknesses/SNPs

> associated with ASD:

>

> MTHFR (C677T and A1298C). MTHFR is a key enzyme in folate

> metabolism, facilitating remethylation.

> COMT. COMT is a key enzyme in the deactivation of catechol

compounds

> such as adrenal hormones, oestrogens, various chemicals and

toxins.

> COMT is important for modulating the neurotransmitter functions of

> dopamine and noradrenaline

> GST. GST is responsible for Phase Two detoxification in the liver

of

> xenobiotics (chemical toxins), carcinogens, end products of

> oxidative stress. The need for high levels of glutathione will be

> highlighted.

> APOE: These multifunctional receptors, known to regulate

cholesterol

> transport, are becoming increasingly interesting to the

neuroscience

> community due to their ability to transduce a diversity of

> extracellular signals across the membrane in the adult CNS. In

> addition, genetic, biochemical and behavioral studies have

> implicated these signaling systems in a number of human

> neurodegenerative and neuropsychiatric disorders involving loss of

> cognitive ability, such as Alzheimer's disease, schizophrenia and

> autism. The presence of the two cysteines in APO-E2 are capable of

> mercury binding and therefore mercury removal from the central

> nervous system. APO-E4 differs from APO-E2 in that these two

> cysteines have been genetically replaced by arginines that have no

> mercury binding acitivity.

> VDR. VDR = Vitamin D Receptor; VDR is an intracellular hormone

> receptor that specifically binds the active form of Vitamin D and

> interacts with target-cell nuclei to produce effects. Interacts

with

> calciums levels, so important in ASD

> Cost of this panel is £368

>

>

>

>

>

> -------------------------------------------------------------------

--

> -----------

>

> Immunogenomic Panel:

>

> Chronic inflammation:

>

> IL-1 beta (interleukin-1 beta).

> IL-1RN

> TH-1 Cytokine:

>

> TNF-alpha (Tumour-Necrosis Factor-alpha)

> TH-2 Cytokines:

>

> IL-4.

> IL-6.

> IL-10.

> IL-13.

> Cost of this Panel £213

>

[Guest guest]

Zoe,

Yes, you're right. You can order a Genetic Analysis Review -- mine

was 82 pages with appendices and diagrams. Dr. Yasko will soon also

have a nutritinal chart of some kind telling you how much of a need

for various supplements the genetics indicates. I will order that,

too, once it comes out -- should be very cheap. Many people don't

order the GAR ($500), but instead choose to spend time on the Autism

Answer discussion forum site and get their answers for the genetics

there. I spend hours each day there, it seems (well, not as much

since I started the YaskoEurope group and we started having all

these interesting conversations over here - LOL), but I still opted

for the GAR given that we have seen so much progress with Lulu and

that this is our big " shot " at giving her a better chance in life.

It just seemed worth it to me and we do have a tiny bit of savings --

and of course all that is earmartked for Lulu and our future as a

family -- you all know the drill here. Plus I love getting the

science stuff from Yasko, then looking it all up on PubMed -- I've

turned into such a GEEK in my old age! I swear, this is my social

life these days! HA HA!

Hugs,

Theresa

> >

> >

> > In a message dated 28/09/2006 14:50:30 GMT Daylight Time,

> > joanne@ writes:

> >

> > Cost of this panel is £368

> >

> >

> > Hi Jo,

> >

> > Do you think a lot of people will take this up when the actual

yasko

> full

> > panel is only (only, I say!!) $750 which I think is around

£400...

> You see if

> > you go staright to the horses mouth so to speak you have all the

> backing of

> > Yasko-philes too dont you??

> >

> > If it was half the price I would consider this route but with

such a

> small

> > difference, mmm, with the Yasko stuff you do get a book and DVD

too

> remember...

> >

> > Just a thought

> > Lotsa Love Caroline

> > xxx

> >

> > PS I just worked out at todays exchange rate (Jeans test is $691,

> thats a

> > lot compared to the $750, dont you think), when I had the Yasko

done

> a coupla

> > months ago it was $750, that may have changed, of course,

JMHO....

> >

>