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Adrenal vein catheterization is the AVS test.

If your question is money, have your endo refer your case to NIH. It is free there.

Bindner

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From: MaxJasper <maxjasper@...>Subject: Posture Testhyperaldosteronism Date: Monday, December 28, 2009, 11:33 PM

Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:

In addition, the posture test is used as a dynamic test to differentiate between an aldosterone- producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is

Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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No, I am trying to avoid AVS for now unless I find it absolutely necessary and that there is no alternative for it. Then, I need to find an old British or German experienced radiologist with a minimum of 50 AVS under his belt PLUS he must be diagnosed with severe case of psychological OCD! I've found an experienced one with those attributes but he is a dermatologist!How about "Posture Test", what is it?Max.>> Adrenal vein catheterization is the AVS test.> > If your question is money, have your endo refer your case to NIH. It is free there.> > Bindner>

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We abandoned this test in about 1976 or so but you can try it if you want to spend the time and money and run the risk of having surgery that will not help your condition. How old is this reference?After over night fast you measure P aldo before getting out of bed and they after 4 hours of standing. In PA it tends to go down. What is the date of this test. Maybe if you are German it works better. CE Grim MD On Dec 28, 2009, at 10:33 PM, MaxJasper wrote:Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:In addition, the posture test is used as a dynamic test to differentiate between an aldosterone-producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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We abandoned this test in about 1976 or so but you can try it if you want to spend the time and money and run the risk of having surgery that will not help your condition. How old is this reference?After over night fast you measure P aldo before getting out of bed and they after 4 hours of standing. In PA it tends to go down. What is the date of this test. Maybe if you are German it works better. CE Grim MD On Dec 28, 2009, at 10:33 PM, MaxJasper wrote:Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:In addition, the posture test is used as a dynamic test to differentiate between an aldosterone-producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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Thanks for the info on Posture Test. It appears that Germans are still using it as part of their recommended diagnostic procedure in suspected PA as shown in page 2 of the following doc dated 2009:

The Diagnosis and Treatment of Primary Hyperaldosteronism in GermanyResults on 555 Patients From the German Conn RegistryCaroline Schirpenbach, Felix Segmiller, Sven Diederich, Stefanie Hahner, Reinhard Lorenz,Lars C. Rump, Jochen Seufert, Marcus Quinkler, Bidlingmaier, Felix Beuschlein, Stephan Endres, Reinckehttp://ukpmc.ac.uk/picrender.cgi?artid=1769079 & blobtype=pdf

I was hoping that based on this doc, Posture Test (PT) can directly take me to APA (20% chance) when PT indicates that PAC is lowered or stayed the same; but if PT indicates that PAC is raised (80% chance) then I move to AVS.

Max.

-----Original Message-----From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of Clarence GrimSent: Monday, December 28, 2009 23:11hyperaldosteronism Subject: Re: Posture TestWe abandoned this test in about 1976 or so but you can try it if you want to spend the time and money and run the risk of having surgery that will not help your condition.

How old is this reference?

After over night fast you measure P aldo before getting out of bed and they after 4 hours of standing. In PA it tends to go down.

What is the date of this test.

Maybe if you are German it works better.

CE Grim MD

On Dec 28, 2009, at 10:33 PM, MaxJasper wrote:

Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:

In addition, the posture test is used as a dynamic test to differentiate between an aldosterone-producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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Thanks for the info on Posture Test. It appears that Germans are still using it as part of their recommended diagnostic procedure in suspected PA as shown in page 2 of the following doc dated 2009:

The Diagnosis and Treatment of Primary Hyperaldosteronism in GermanyResults on 555 Patients From the German Conn RegistryCaroline Schirpenbach, Felix Segmiller, Sven Diederich, Stefanie Hahner, Reinhard Lorenz,Lars C. Rump, Jochen Seufert, Marcus Quinkler, Bidlingmaier, Felix Beuschlein, Stephan Endres, Reinckehttp://ukpmc.ac.uk/picrender.cgi?artid=1769079 & blobtype=pdf

I was hoping that based on this doc, Posture Test (PT) can directly take me to APA (20% chance) when PT indicates that PAC is lowered or stayed the same; but if PT indicates that PAC is raised (80% chance) then I move to AVS.

Max.

-----Original Message-----From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of Clarence GrimSent: Monday, December 28, 2009 23:11hyperaldosteronism Subject: Re: Posture TestWe abandoned this test in about 1976 or so but you can try it if you want to spend the time and money and run the risk of having surgery that will not help your condition.

How old is this reference?

After over night fast you measure P aldo before getting out of bed and they after 4 hours of standing. In PA it tends to go down.

What is the date of this test.

Maybe if you are German it works better.

CE Grim MD

On Dec 28, 2009, at 10:33 PM, MaxJasper wrote:

Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:

In addition, the posture test is used as a dynamic test to differentiate between an aldosterone-producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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I would see if they require an overnight stay in a hospital for this to proper time the supine and upright sampling. My guess is is most useful in advanced PA. If they do it is not likely that you can get insurance to pay for hospitalization-unless your are German.On Dec 29, 2009, at 12:55 AM, MaxJasper wrote:Thanks for the info on Posture Test. It appears that Germans are still using it as part of their recommended diagnostic procedure in suspected PA as shown in page 2 of the following doc dated 2009:The Diagnosis and Treatment of Primary Hyperaldosteronism in GermanyResults on 555 Patients From the German Conn RegistryCaroline Schirpenbach, Felix Segmiller, Sven Diederich, Stefanie Hahner, Reinhard Lorenz,Lars C. Rump, Jochen Seufert, Marcus Quinkler, Bidlingmaier, Felix Beuschlein, Stephan Endres, Reinckehttp://ukpmc.ac.uk/picrender.cgi?artid=1769079 & blobtype=pdf I was hoping that based on this doc, Posture Test (PT) can directly take me to APA (20% chance) when PT indicates that PAC is lowered or stayed the same; but if PT indicates that PAC is raised (80% chance) then I move to AVS. Max. Re: Posture TestWe abandoned this test in about 1976 or so but you can try it if you want to spend the time and money and run the risk of having surgery that will not help your condition. How old is this reference?After over night fast you measure P aldo before getting out of bed and they after 4 hours of standing. In PA it tends to go down. What is the date of this test. Maybe if you are German it works better. CE Grim MD On Dec 28, 2009, at 10:33 PM, MaxJasper wrote:Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:In addition, the posture test is used as a dynamic test to differentiate between an aldosterone-producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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I would see if they require an overnight stay in a hospital for this to proper time the supine and upright sampling. My guess is is most useful in advanced PA. If they do it is not likely that you can get insurance to pay for hospitalization-unless your are German.On Dec 29, 2009, at 12:55 AM, MaxJasper wrote:Thanks for the info on Posture Test. It appears that Germans are still using it as part of their recommended diagnostic procedure in suspected PA as shown in page 2 of the following doc dated 2009:The Diagnosis and Treatment of Primary Hyperaldosteronism in GermanyResults on 555 Patients From the German Conn RegistryCaroline Schirpenbach, Felix Segmiller, Sven Diederich, Stefanie Hahner, Reinhard Lorenz,Lars C. Rump, Jochen Seufert, Marcus Quinkler, Bidlingmaier, Felix Beuschlein, Stephan Endres, Reinckehttp://ukpmc.ac.uk/picrender.cgi?artid=1769079 & blobtype=pdf I was hoping that based on this doc, Posture Test (PT) can directly take me to APA (20% chance) when PT indicates that PAC is lowered or stayed the same; but if PT indicates that PAC is raised (80% chance) then I move to AVS. Max. Re: Posture TestWe abandoned this test in about 1976 or so but you can try it if you want to spend the time and money and run the risk of having surgery that will not help your condition. How old is this reference?After over night fast you measure P aldo before getting out of bed and they after 4 hours of standing. In PA it tends to go down. What is the date of this test. Maybe if you are German it works better. CE Grim MD On Dec 28, 2009, at 10:33 PM, MaxJasper wrote:Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:In addition, the posture test is used as a dynamic test to differentiate between an aldosterone-producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

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MaxI think it is just best to have an AVS - it is a straight forward procedure if done by experts. The real issue is to try and find people who are expert at doing AVS. I was in and out back at work within hours. Hi all,I found the following statement regarding Posture Test which indicates that there is 20% chance that I can skip AVS:In addition, the posture test is used as a dynamic test to differentiate between an aldosterone- producing adenoma and bilateral adrenal hyperplasia. If the posture test shows decreased aldosterone and imaging

demonstrates a circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If the findings of the function test and diagnostic imaging are incongruentâ€"as is the case in over 80% of patientsâ€"the next step is adrenal vein catheterization, the gold standard for differential diagnosis of the various subtypes (12, 14â€"16). [-The Diagnosis and Treatment of Primary Hyperaldosteronism in

Germany ]Question:What is Posture Test? Details or a link to detailed description is very much appreciated. Thanks.Max.

See what's on at the movies in your area. Find out now.

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Where did you go? It looks like MN or TX are the only places with experts from

what I see. Is it really worth flying there to have the test if you live

somewhere else? (I live in Ohio)

> Hi all,

>

> I found the following statement regarding Posture Test which indicates that

there is 20% chance that I can skip AVS:

>

> In addition, the posture test is used as a dynamic test to differentiate

between an aldosterone- producing adenoma and bilateral adrenal hyperplasia. If

the  posture test shows decreased aldosterone and imaging demonstrates a

circumscribed adrenal mass, an aldosterone producing adenoma can be assumed. If

the findings of the function test and diagnostic imaging are

incongruent†" as is the case in over 80% of patients†" the next step

is adrenal vein catheterization, the gold standard for differential diagnosis

of the various subtypes (12, 14†" 16). [-The Diagnosis and Treatment of

Primary Hyperaldosteronism in Germany ]

>

> Question:

>

> What is Posture Test? Details or a link to detailed description is very much

appreciated. Thanks.

>

> Max.

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

________________________________________________________________________________\

__

> See what's on at the movies in your area. Find out now:

http://au.movies./session-times/

>

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I'm about an hour east of Cleveland, so UofM would definitely be closer than MN

- about a 4 hour drive. thanks.

> > > Hi all,

> > >

> > > I found the following statement regarding Posture

> > Test which indicates that there is 20% chance that I can

> > skip AVS:

> > >

> > > In addition, the posture test is used as a

> > dynamic test to differentiate between an aldosterone-

> > producing adenoma and bilateral adrenal hyperplasia. If

> > the  posture test shows decreased aldosterone and

> > imaging demonstrates a circumscribed adrenal mass, an

> > aldosterone producing adenoma can be assumed. If the

> > findings of the function test and diagnostic imaging

> > are incongruent†" as is the case in

> > over 80% of patients†" the next step

> > is adrenal vein catheterization, the gold standard for

> > differential diagnosis of the various subtypes (12,

> > 14†" 16). [-The Diagnosis and Treatment of

> > Primary Hyperaldosteronism in Germany ]

> > >

> > > Question:

> > >

> > > What is Posture Test? Details or a link to detailed

> > description is very much appreciated. Thanks.

> > >

> > > Max.

> > >

> > >

> > >

> > >

> > >     

> > >     

> > >

> > >     

> > >     

> > >

> > >

> > > 

> > >

> > >

> > >

> > >   

> > >

> > >

> > >

> > >

> > >

> > >

> > >   

> >

   __________________________________________________________________________\

________

> > > See what's on at the movies in your area. Find out

> > now: http://au.movies./session-times/

> > >

> >

> >

> >

> >

> > ------------------------------------

> >

> >

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Thank-you, Dr. Grim! I will look them up. Saw my endo today and they didn't

have the results from the salt loading test yet, but I told him about the urine

output and he seemed to be aware of the salt dumping in PA. He is trying me on

Spiro to see if I tolerate it before doing any more testing. I think I would

like to switch to someone with more experience in PA at this point in time and

it looks like that is one of Dr. Bravo's specialties. He's only 45 minutes from

me - even better!

> > > > > Hi all,

> > > > >

> > > > > I found the following statement regarding Posture

> > > > Test which indicates that there is 20% chance that I can

> > > > skip AVS:

> > > > >

> > > > > In addition, the posture test is used as a

> > > > dynamic test to differentiate between an aldosterone-

> > > > producing adenoma and bilateral adrenal hyperplasia. If

> > > > the  posture test shows decreased aldosterone and

> > > > imaging demonstrates a circumscribed adrenal mass, an

> > > > aldosterone producing adenoma can be assumed. If the

> > > > findings of the function test and diagnostic imaging

> > > > are incongruent†" as is the case in

> > > > over 80% of patients†" the next step

> > > > is adrenal vein catheterization, the gold standard for

> > > > differential diagnosis of the various subtypes (12,

> > > > 14†" 16). [-The Diagnosis and Treatment of

> > > > Primary Hyperaldosteronism in Germany ]

> > > > >

> > > > > Question:

> > > > >

> > > > > What is Posture Test? Details or a link to detailed

> > > > description is very much appreciated. Thanks.

> > > > >

> > > > > Max.

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >Â Â Â Â

> > > > >Â Â Â

> > > > >

> > > > >Â Â Â Â

> > > > >Â Â Â Â

> > > > >

> > > > >

> > > > >Â

> > > > >

> > > > >

> > > > >

> > > > >Â Â Â

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >Â Â

> > > > Â Â Â __________________________________________________________

> > > > > See what's on at the movies in your area. Find out

> > > > now: http://au.movies./session-times/

> > > > >

> > > >

> > > >

> > > >

> > > >

> > > > ------------------------------------

> > > >

> > > >

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If I read this correctly then, very small doses of Spiro in combination with

HCTZ or low sodium diet are more effective than large doses of Spiro alone. My

current orders are to gradually increase Spiro to 400mg per day while cutting

back and then eliminating HCTZ and Verapamil. There is an obvious difference of

philosophy/treatment here between Dr. Bravo and my endo.

> > > > > > > Hi all,

> > > > > > >

> > > > > > > I found the following statement regarding Posture

> > > > > > Test which indicates that there is 20% chance that I c

> > an

> > > > > > skip AVS:

> > > > > > >

> > > > > > > In addition, the posture test is used as a

> > > > > > dynamic test to differentiate between an aldosterone-

> > > > > > producing adenoma and bilateral adrenal hyperplasia. If

> > > > > > the  posture test shows decreased

> > aldosterone and

> > > > > > imaging demonstrates a circumscribed adrenal mass, an

> > > > > > aldosterone producing adenoma can be assumed. If the

> > > > > > findings of the function test and diagnostic

> > imaging

> > > > > > are incongruentÃÆ'¢â‚¬ " as is the case in

> > > > > > over 80% of patientsÃÆ'¢â‚¬ " the

> > next step

> > > > > > is adrenal vein catheterization, the gold standard for

> > > > > > differential diagnosis of the various subtypes (12,

> > > > > > 14ÃÆ'¢â‚¬ " 16). [-The Diagnosis and

> > Treatment of

> > > > > > Primary Hyperaldosteronism in Germany ]

> > > > > > >

> > > > > > > Question:

> > > > > > >

> > > > > > > What is Posture Test? Details or a link to detailed

> > > > > > description is very much appreciated. Thanks.

> > > > > > >

> > > > > > > Max.

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >Â Â Â Â

> > > > > > >Â Â Â

> > > > > > >

> > > > > > >Â Â Â Â

> > > > > > >Â Â Â Â

> > > > > > >

> > > > > > >

> > > > > > >Â

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >Â Â Â

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > >Â Â

> > > > > > Â Â Â

> > __________________________________________________________

> > > > > > > See what's on at the movies in your area. Find out

> > > > > > now: http://au.movies./session-times/

> > > > > > >

> > > > > >

> > > > > >

> > > > > >

> > > > > >

> > > > > > ------------------------------------

> > > > > >

> > > > > >

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