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Re: Depakote?

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this is the drug that is being used along with carnitor in one of hte clinical

drug trails that are going on. My son is on it and has been for 2 years now.

hugs

kenya

Joy <j0yeuxx@...> wrote:

Hi all-

I've never seen a neuro in my adult years, but since lately I feel like sma

has been progressing I thought it might be a good idea. I've contacted the

people to see

the only one in the area. It takes about 3 months to get in. To make a long

story short, I just got on e-mail from him asking me if I would be willing to

start taking Depakote before coming to see him. This kind of took me by surprise

as I have no idea what it is, or why he could suggest it without ever seeing me.

Can any of you share your experiences of this? Do any of you take this?

I will look into what it is more when I get home. (yes I am bad and typing

this from work). I just wanted to know some info from other SMAers who know what

it's all about. Thank you.

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> I will look into what it is more when I get home. (yes I am bad and

> typing this from work). I just wanted to know some info from other

> SMAers who know what it's all about. Thank you.

here...

http://everything2.com/index.pl?node_id=765681

....i say find another doctor

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AOL-IM : BardsDirge

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for two. "

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No experience with this but I think it is irresponsible of him to ask

you to take a medication before seeing you. He has no idea what other

medications you may be on or what other illnesses you may have which may

be contraindicated with Depakote.

From a two second net search I found this:

Most important fact about Depakote

Depakote can cause serious or even fatal liver damage, especially during

the first 6 months of treatment. Children under 2 years of age are the

most vulnerable, especially if they are also taking other anticonvulsant

medicines and have certain other disorders such as mental retardation.

The risk of liver damage decreases with age; but you should always be

alert for the following symptoms: loss of seizure control, weakness,

dizziness, drowsiness, a general feeling of ill health, facial swelling,

loss of appetite, vomiting, and yellowing of the skin and eyes. If you

suspect a liver problem, call your doctor immediately.

Depakote has also been known to cause life-threatening damage to the

pancreas. This problem can surface at any time, even after years of

treatment. Call your doctor immediately if you develop any of the

following warning signs: abdominal pain, loss of appetite, nausea, or

vomiting.

http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dep1125.shtml

L

Joy wrote:

> Hi all-

> I've never seen a neuro in my adult years, but since lately I feel

> like sma has been progressing I thought it might be a good idea. I've

> contacted the people to see

> the only one in the area. It takes about 3 months to get in. To make

> a long story short, I just got on e-mail from him asking me if I would

> be willing to start taking Depakote before coming to see him. This

> kind of took me by surprise as I have no idea what it is, or why he

> could suggest it without ever seeing me.

> Can any of you share your experiences of this? Do any of you take this?

> I will look into what it is more when I get home. (yes I am bad and

> typing this from work). I just wanted to know some info from other

> SMAers who know what it's all about. Thank you.

>

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Joy:

I think the best course is for you to read up on the CARNI-VAL trial

(though the information is a little patchy), read up on Depakote,

consult with your PCP, who presumably knows your medical history well,

and then make an informed decision on what's best for you. I was

surprised that any doctor would suggest taking medication before you

see him for the first time, but his e-mail suggests he is genuinely

trying to help.

It's true that there have been some quite dramatic improvements in

young children participating in the trials, but it's also true that

the researchers suspect timing may be important with this medication

(ie. the sooner the treatment is given, the better). They don't KNOW

that yet, because they haven't done any trials in adults with SMA, but

it is another aspect to consider.

As for side effects, EVERY drug has a list of potential side effects,

and most drugs can cause serious side effects in very rare cases.

Depakote has been approved by the FDA for many years, so I think it's

important to keep the risk of side effects in perspective. Since you

are not a child, the risks should not be that great, but only a doctor

who knows you well can make that judgment. To minimize the risks

further, make sure you get the carnitine supplement, and a regular

blood test to check everything is OK would also be a good idea.

Just my two cents (or yen in my case),

Tokyo, Japan

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Guest guest

I think it is great that you are sharing the side effects. yes there can be very

bad side effects that is why it is so important to not do it on your own. I do

know that the level for the medicine is alot less than what is given for siezure

patients so the risk is lower. However it is very important to take the carnitor

with it.

It is irresponsible of a doc to ask you to take it before he sees you. he

should see you first, get an assessment then go from there.

Kenya

Those Two <those2@...> wrote:

No experience with this but I think it is irresponsible of him to ask

you to take a medication before seeing you. He has no idea what other

medications you may be on or what other illnesses you may have which may

be contraindicated with Depakote.

From a two second net search I found this:

Most important fact about Depakote

Depakote can cause serious or even fatal liver damage, especially during

the first 6 months of treatment. Children under 2 years of age are the

most vulnerable, especially if they are also taking other anticonvulsant

medicines and have certain other disorders such as mental retardation.

The risk of liver damage decreases with age; but you should always be

alert for the following symptoms: loss of seizure control, weakness,

dizziness, drowsiness, a general feeling of ill health, facial swelling,

loss of appetite, vomiting, and yellowing of the skin and eyes. If you

suspect a liver problem, call your doctor immediately.

Depakote has also been known to cause life-threatening damage to the

pancreas. This problem can surface at any time, even after years of

treatment. Call your doctor immediately if you develop any of the

following warning signs: abdominal pain, loss of appetite, nausea, or

vomiting.

http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dep1125.shtml

L

Joy wrote:

> Hi all-

> I've never seen a neuro in my adult years, but since lately I feel

> like sma has been progressing I thought it might be a good idea. I've

> contacted the people to see

> the only one in the area. It takes about 3 months to get in. To make

> a long story short, I just got on e-mail from him asking me if I would

> be willing to start taking Depakote before coming to see him. This

> kind of took me by surprise as I have no idea what it is, or why he

> could suggest it without ever seeing me.

> Can any of you share your experiences of this? Do any of you take this?

> I will look into what it is more when I get home. (yes I am bad and

> typing this from work). I just wanted to know some info from other

> SMAers who know what it's all about. Thank you.

>

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Guest guest

I would like to think he would write an Rx for some blood work before

he writes the script. I would respond and ask what the routine to start

it would be and go from there. I can't see a doctor just start sending

out scripts I think he may have just wanted to see if you are open to

the idea. I am going to see my neurologist and ask about this for

myself. I am 33 type III but would like to give it a shot.

Terry

> It is irresponsible of a doc to ask you to take it before he sees

you. he should see you first, get an assessment then go from there.

>

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Guest guest

I think I mentioned this before on here.

I had a horrible reaction to the

Depakote/Carnitine thingy. After about

a month, I slowly developed severe joint

point. I couldn't move my arms or even

fingers, because it hurt so much. I can

move my legs a little, and the joints in

my legs hurt too. I stopped Depakote

and after 2-3 days, I felt better. My

MD doc started me on 300mg of Depakote.

No improvement in energy or strength,

despite the side effects. I was very

disappointed.

Eternal Blessings,

Meg.

* (My Blog:

<http://360./pink-tulip@amerite

ch.net>

http://360./pink-tulip@ameritec

h.net)

_____

From:

[mailto: ] On

Behalf Of Kenya Birkle

Sent: Wednesday, March 01, 2006 9:43 AM

Subject: Re: Depakote?

I think it is great that you are sharing

the side effects. yes there can be very

bad side effects that is why it is so

important to not do it on your own. I do

know that the level for the medicine is

alot less than what is given for siezure

patients so the risk is lower. However

it is very important to take the

carnitor with it.

It is irresponsible of a doc to ask

you to take it before he sees you. he

should see you first, get an assessment

then go from there.

Kenya

Those Two <those2@...> wrote:

No experience with this but I think it

is irresponsible of him to ask

you to take a medication before seeing

you. He has no idea what other

medications you may be on or what other

illnesses you may have which may

be contraindicated with Depakote.

From a two second net search I found

this:

Most important fact about Depakote

Depakote can cause serious or even fatal

liver damage, especially during

the first 6 months of treatment.

Children under 2 years of age are the

most vulnerable, especially if they are

also taking other anticonvulsant

medicines and have certain other

disorders such as mental retardation.

The risk of liver damage decreases with

age; but you should always be

alert for the following symptoms: loss

of seizure control, weakness,

dizziness, drowsiness, a general feeling

of ill health, facial swelling,

loss of appetite, vomiting, and

yellowing of the skin and eyes. If you

suspect a liver problem, call your

doctor immediately.

Depakote has also been known to cause

life-threatening damage to the

pancreas. This problem can surface at

any time, even after years of

treatment. Call your doctor immediately

if you develop any of the

following warning signs: abdominal pain,

loss of appetite, nausea, or

vomiting.

http://www.pdrhealth.com/drug_info/rxdru

gprofiles/drugs/dep1125.shtml

L

Joy wrote:

> Hi all-

> I've never seen a neuro in my adult

years, but since lately I feel

> like sma has been progressing I

thought it might be a good idea. I've

> contacted the people to see

> the only one in the area. It takes

about 3 months to get in. To make

> a long story short, I just got on

e-mail from him asking me if I would

> be willing to start taking Depakote

before coming to see him. This

> kind of took me by surprise as I have

no idea what it is, or why he

> could suggest it without ever seeing

me.

> Can any of you share your

experiences of this? Do any of you take

this?

> I will look into what it is more

when I get home. (yes I am bad and

> typing this from work). I just wanted

to know some info from other

> SMAers who know what it's all about.

Thank you.

>

A FEW RULES

* The list members come from many

backgrounds, ages and beliefs So all

members most be tolerant and respectful

to all members.

* Some adult language and topics (like

sexual health, swearing..) may

occur occasionally in emails. Over use

of inappropriate language will

not be allowed. If your under 16 ask

your parents/gaurdian before you

join the list.

* No SPAMMING or sending numerous emails

unrelated to the topics of

spinal muscular atrophy, health, and the

daily issues of the disabled.

Post message:

Subscribe:

-subscribe

Unsubscribe:

-unsubscribe

List manager: (Sexy Mature

Artist) Email: Esma1999@...

oogroups.com

List manager: (Sexy Mature

Artist) Email: Esma1999@...

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