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Pregnancy and Heredity

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With CMT 1A, because it is autosomal dominant, you have a 50/50

chance of your child inheriting CMT. As for mildness or severity,

that has been proved to be SO different among members of the same

family, just like symptoms can be.

I personally chose not to have children - this was before all the DNA

testing was done, but I had a good enough clue that even without CMT

in my family, I could pass what I had on to offspring, and I did not

want to give a child the CMT gift. I also questioned my own physical

health in regards to pregnancy, and even though all docs said I was

fine and could do it, I doubted myself, knowing what my body can and

cannot handle.

Now, here is something to consider: There is Pre-Implantation Genetic

Diagnosis available for CMT 1A persons (and a few other types) This

is a type of in-vitro where the CMT gene is taken out, long story

short, this results in a CMT-free child. Go to our Files section,

look under " Research Reports " (in simple terms) there is the research

and article I wrote on this for CMTWORLD. You just might want to look

at this.

~ Gretchen

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