Guest guest Posted September 17, 2005 Report Share Posted September 17, 2005 We tried it about a yr ago, it didn't do anything for at all. Bought it because so many parents reported great improvements inc language, didn't do any harm either though. Vicky Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 17, 2005 Report Share Posted September 17, 2005 In a message dated 17/09/2005 16:56:48 GMT Daylight Time, mark.grabiec@... writes: What does this do? I bought some a while back on someone's recommendation and the bottle is not giving much away. I've lost track of who recommended it now! (That's what you get with access to a world of advice - what would we do without it?)NOt sure what it would add to TOm's regime, not due to chat to Dr Heard until NOvember but must have thought it was a good idea as it cost thirty quid! >>>You make me chuckle Steph LOL - found this on LEF.org. (coz I had forgetten too, I rember something about fat digestion - maybe I should take them?) Mandi x A major cause of aging is the deterioration of the energy-producing components of the cell which results in reduced cellular metabolic activity, the accumulation of cellular debris, and eventual death of the cell.1-7* The amino acid L-carnitine helps to maintain cellular energy metabolism by assisting in the transport of fat through the cell membrane and into the mitochondria within the cell, where these fats are oxidized to produce the cellular energy ATP.8-12* Acetyl-l-carnitine is the acetylated ester of the amino acid L-carnitine. Acetyl-l-carnitine and L-carnitine are absorbed into the bloodstream efficiently and both are very effective at carrying fatty acids across the membrane into the cell where they are burned as energy and is utilized efficiently in the mitochondria of the cell.13-14 References About 95% of cellular energy occurs in the mitochondria.95 Acetyl-l-carnitine is the biologically active amino acid involved in the transport of fatty acids into the cell’s mitochondria for the purpose of producing energy.96-99 Acetyl-l-carnitine easily crosses the blood-brain barrier and may have potential in preserving neurological function.100-103* Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 17, 2005 Report Share Posted September 17, 2005 Aha! Preserving brain function is clearly something I could do with myself! Many thanks Steph x > > In a message dated 17/09/2005 16:56:48 GMT Daylight Time, > mark.grabiec@n... writes: > > What does this do? I bought some a while back on someone's > recommendation and the bottle is not giving much away. I've lost > track of who recommended it now! (That's what you get with access to > a world of advice - what would we do without it?) > > NOt sure what it would add to TOm's regime, not due to chat to Dr > Heard until NOvember but must have thought it was a good idea as it > cost thirty quid! > > > > >>>You make me chuckle Steph LOL - found this on LEF.org. (coz I had > forgetten too, I rember something about fat digestion - maybe I should take them?) > Mandi x > > > A major cause of aging is the deterioration of the energy- producing > components of the cell which results in reduced cellular metabolic activity, the > accumulation of cellular debris, and eventual death of the cell.1- 7* > The amino acid L-carnitine helps to maintain cellular energy metabolism by > assisting in the transport of fat through the cell membrane and into the > mitochondria within the cell, where these fats are oxidized to produce the > cellular energy ATP.8-12* > Acetyl-l-carnitine is the acetylated ester of the amino acid L- carnitine. > Acetyl-l-carnitine and L-carnitine are absorbed into the bloodstream > efficiently and both are very effective at carrying fatty acids across the membrane > into the cell where they are burned as energy and is utilized efficiently in the > mitochondria of the cell.13-14 _References_ > (javascript:itemReferencePopUp ('/newshop/items/references/aminoacids.htm') > About 95% of cellular energy occurs in the mitochondria.95 Acetyl- l-carnitine > is the biologically active amino acid involved in the transport of fatty > acids into the cell’s mitochondria for the purpose of producing energy.96-99 > Acetyl-l-carnitine easily crosses the blood-brain barrier and may have > potential in preserving neurological function.100-103* Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 17, 2005 Report Share Posted September 17, 2005 Hi, It is a fat transporter so if you are supplementing with COL or fatty acids, L cartinine is a nice addition. > Hi Chaps > > What does this do? I bought some a while back on someone's > recommendation and the bottle is not giving much away. I've lost > track of who recommended it now! (That's what you get with access to > a world of advice - what would we do without it?) > > NOt sure what it would add to TOm's regime, not due to chat to Dr > Heard until NOvember but must have thought it was a good idea as it > cost thirty quid! > > ?? > > Steph x Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2005 Report Share Posted October 17, 2005 Jo, Haven't ever seen anything about research on L carnitine and CMT, but read below for something on diabetic neuropathy. You may find some parellels. ~ Gretchen Diabetes Care. 2005 Jan;28(1):89-94. Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials. Sima AA, Calvani M, Mehra M, Amato A; Acetyl-L-Carnitine Study Group. Department of Pathology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. OBJECTIVE: We evaluated frozen databases from two 52-week randomized placebo-controlled clinical diabetic neuropathy trials testing two doses of acetyl-L-carnitine (ALC): 500 and 1,000 mg/day t.i.d. RESEARCH DESIGN AND METHODS: Intention-to-treat patients amounted to 1,257 or 93% of enrolled patients. Efficacy end points were sural nerve morphometry, nerve conduction velocities, vibration perception thresholds, clinical symptom scores, and a visual analogue scale for most bothersome symptom, most notably pain. The two studies were evaluated separately and combined. RESULTS: Data showed significant improvements in sural nerve fiber numbers and regenerating nerve fiber clusters. Nerve conduction velocities and amplitudes did not improve, whereas vibration perception improved in both studies. Pain as the most bothersome symptom showed significant improvement in one study and in the combined cohort taking 1,000 mg ALC. CONCLUSIONS: These studies demonstrate that ALC treatment is efficacious in alleviating symptoms, particularly pain, and improves nerve fiber regeneration and vibration perception in patients with established diabetic neuropathy. Quote Link to comment Share on other sites More sharing options...
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