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Scientists Find a Switch that Renews Sperm-Producing Stem Cells

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Research News from the Medical Institute

Scientists Find a Switch that Renews Sperm-Producing Stem Cells

HHMI researchers have discovered a master genetic switch that regulates

the self-renewal of sperm-producing stem cells. Mice that were

genetically engineered to lack the switch quickly exhausted their sperm-

producing stem cells, rendering them incapable of producing sperm.

Research published in the August 18, 2005, issue of Nature.

HHMI investigator(s):

M. , M.D., Ph.D., Washington University School of

Medicine in St. Louis

For the full story, go to http://www.hhmi.org//news/murphy.html

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