Re: Re: Alzheimer's drugs cause brain damage

[Guest guest]

Hi Shan,

As far as you (or anyone else) know, does magnesium have any protective

action wrt fluoride?

As a side note, I recall reading that if plants do not have access to the

" good " minerals that they're

more apt to absorb bad ones like cadmium. Maybe we humans have something similar

going on.

Peace, D. Mindock

Re: Alzheimer's drugs cause brain damage

I have come across information about Alzheimer's and magnesium in 2 different

books now by different doctors. Magnesium also evidently protects the brain from

toxins including aluminium.

Most drugs deplete magnesium , so it is not surprising to me that drugs worsen

any disorder that is one that particularly needs magnesium.

blessings

Shan

>

> Alzheimer's drugs cause brain damage and actually worsen memory loss

> Wednesday, April 21, 2010 by: S. L. Baker

>

> http://www.naturalnews.com/028622_Alzheimers_brain_damage.html

>

>

[Guest guest]

bummer,  we use a carbon filter for our drinking water, however it leaves

the flouride in which I don't want.  I was thinking I was getting my minerals

including mg, but according to this, the flouride diminishes the mg being

absorbed.  " bummer " I guess we won't be cooking vegetables with it either.  

Too bad the city of Austin, Tx  puts flouride in the drinking water. (some say

this is " forced " medication "

Another solution is to buy spring or mineral water that already has the proper

amounts of minerals. Mountain Valley Spring Water (from Hot Springs National

Park, Arkansas) comes to mind. Expensive, yes, so we limit what we use.  S.J.

From: surpriseshan2@... <surpriseshan2@...>

Subject: Re: Alzheimer's drugs cause brain damage

Longevity

Date: Thursday, April 22, 2010, 2:15 PM

 

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g. in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing to

high chemical affinity of both elements and production of MgF+ and MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme systematics.

Magnesium

is the activator of more than 300 enzymes, while fluorine is known as their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F- interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of Mg

into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs and

molars. This is undoubtedly related to the assimilability of both elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example, magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11, 12)

and prevents its annealing, but this effect diminishes after administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that it

is calcium rather than magnesium that intensifies mineralization processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8) Formation

of

uroliths follows crystallization rules. Mg ion reduces the rate of superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society 76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3) 456-500,

1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

------------ --------- --------- --------- --------- --------- -

----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

> >

> > Alzheimer's drugs cause brain damage and actually worsen memory loss

> > Wednesday, April 21, 2010 by: S. L. Baker

> >

> > _http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html_

(http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html)

> >

>

[Guest guest]

A reverse-osmosis filter will remove flouride.

Re: Alzheimer's drugs cause brain damage

Longevity

Date: Thursday, April 22, 2010, 2:15 PM

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The

toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount

of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g.

in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new

light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with

the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under

the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing

to

high chemical affinity of both elements and production of MgF+ and

MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and

tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants

against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP

levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme

systematics. Magnesium

is the activator of more than 300 enzymes, while fluorine is known as

their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F-

interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of

Mg into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs

and

molars. This is undoubtedly related to the assimilability of both

elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example,

magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances

Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11,

12)

and prevents its annealing, but this effect diminishes after

administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive

enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as

demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that

it

is calcium rather than magnesium that intensifies mineralization

processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8)

Formation of

uroliths follows crystallization rules. Mg ion reduces the rate of

superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and

accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society

76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica

Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3)

456-500, 1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal

layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium

on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

------------ --------- --------- --------- --------- --------- -

----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

> >

> > Alzheimer's drugs cause brain damage and actually worsen memory loss

> > Wednesday, April 21, 2010 by: S. L. Baker

> >

> > _http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html_

(http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html)

> >

>

[Guest guest]

thanks for the info on a reverse osmosis filter to remove flouride. My next

question is: does it remove the good minerals as well?

From: surpriseshan2@ aol.com <surpriseshan2@ aol.com>

Subject: Re: Alzheimer's drugs cause brain damage

Longevity@grou ps.com

Date: Thursday, April 22, 2010, 2:15 PM

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The

toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount

of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g.

in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new

light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with

the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under

the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing

to

high chemical affinity of both elements and production of MgF+ and

MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and

tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants

against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP

levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme

systematics. Magnesium

is the activator of more than 300 enzymes, while fluorine is known as

their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F-

interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of

Mg into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs

and

molars. This is undoubtedly related to the assimilability of both

elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example,

magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances

Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11,

12)

and prevents its annealing, but this effect diminishes after

administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive

enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as

demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that

it

is calcium rather than magnesium that intensifies mineralization

processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8)

Formation of

uroliths follows crystallization rules. Mg ion reduces the rate of

superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and

accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society

76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica

Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3)

456-500, 1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal

layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium

on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

------------ --------- --------- --------- --------- --------- -

----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

> >

> > Alzheimer's drugs cause brain damage and actually worsen memory loss

> > Wednesday, April 21, 2010 by: S. L. Baker

> >

> > _http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html_

(http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html)

> >

>

[Guest guest]

Yes, but you can add them back with a very inexpensive mineral mixture.

Re: Alzheimer's drugs cause brain damage

Longevity@grou ps.com

Date: Thursday, April 22, 2010, 2:15 PM

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The

toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount

of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g.

in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new

light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with

the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under

the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing

to

high chemical affinity of both elements and production of MgF+ and

MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and

tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants

against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP

levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme

systematics. Magnesium

is the activator of more than 300 enzymes, while fluorine is known as

their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F-

interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of

Mg into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs

and

molars. This is undoubtedly related to the assimilability of both

elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example,

magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances

Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11,

12)

and prevents its annealing, but this effect diminishes after

administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive

enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as

demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that

it

is calcium rather than magnesium that intensifies mineralization

processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8)

Formation of

uroliths follows crystallization rules. Mg ion reduces the rate of

superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and

accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society

76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica

Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3)

456-500, 1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal

layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium

on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

------------ --------- --------- --------- --------- --------- -

----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

> >

> > Alzheimer's drugs cause brain damage and actually worsen memory loss

> > Wednesday, April 21, 2010 by: S. L. Baker

> >

> > _http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html_

(http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html)

> >

>

[Guest guest]

I a pretty sure it does remove the minerals. Reverse osmosis is the next best

thing to distilled water.

But you can add the minerals back by adding a couple of drops of a trace mineral

concentrate.

Here is one that I just googled randomly. There are others.

http://www.vitality4life.com/au/trace-minerals-drops-concentrate-trace-minerals.\

html

Rex

________________________________

From: <samjon11@...>

Longevity

Sent: Sat, April 24, 2010 7:25:17 AM

Subject: Re: Re: Alzheimer's drugs cause brain damage

thanks for the info on a reverse osmosis filter to remove flouride. My next

question is: does it remove the good minerals as well?

From: surpriseshan2@ aol.com <surpriseshan2@ aol.com>

Subject: Re: Alzheimer's drugs cause brain damage

Longevity@grou ps.com

Date: Thursday, April 22, 2010, 2:15 PM

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The

toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount

of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g.

in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new

light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with

the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under

the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing

to

high chemical affinity of both elements and production of MgF+ and

MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and

tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants

against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP

levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme

systematics. Magnesium

is the activator of more than 300 enzymes, while fluorine is known as

their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F-

interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of

Mg into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs

and

molars. This is undoubtedly related to the assimilability of both

elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example,

magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances

Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11,

12)

and prevents its annealing, but this effect diminishes after

administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive

enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as

demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that

it

is calcium rather than magnesium that intensifies mineralization

processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8)

Formation of

uroliths follows crystallization rules. Mg ion reduces the rate of

superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and

accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society

76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica

Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3)

456-500, 1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal

layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium

on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

------------ --------- --------- --------- --------- --------- -

----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

> >

> > Alzheimer's drugs cause brain damage and actually worsen memory loss

> > Wednesday, April 21, 2010 by: S. L. Baker

> >

> > _http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html_

(http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html)

> >

>

[Guest guest]

I read somewhere that reverse osmosis is wasteful of water. Two gallons go

down the drain for each

gallon of filtered water produced. True, tap water is cheap, but it is likely

undervalued, even with the

fluoride in it and who knows what else. Distilling water takes a lot of

energy. I believe that the six

stage filter I use by Crystal Quest which removes fluoride might be the

cheapest way to arrive at

clean water. The good minerals like magnesium aren't affected. All the nasty

ones like lead and cadmium

are filtered out. All the POVs, PCBs, etc are filtered out. I used to use the

Crystal Quest and then follow

with the distillation but decided it was overkill. WRT the Crystal Quest, one

stage is totally dedicated to

removing the fluoride. They do have other filters that don't remove the

fluoride, I guess for the peeps that

still believe fluoride is healthful, if they only knew!

Peace, D Mindock

Yes, but you can add them back with a very inexpensive mineral mixture.

Re: Alzheimer's drugs cause brain damage

Longevity@grou ps.com

Date: Thursday, April 22, 2010, 2:15 PM

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The

toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount

of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g.

in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new

light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with

the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under

the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing

to

high chemical affinity of both elements and production of MgF+ and

MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and

tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants

against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP

levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme

systematics. Magnesium

is the activator of more than 300 enzymes, while fluorine is known as

their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F-

interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of

Mg into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs

and

molars. This is undoubtedly related to the assimilability of both

elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example,

magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances

Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11,

12)

and prevents its annealing, but this effect diminishes after

administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive

enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as

demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that

it

is calcium rather than magnesium that intensifies mineralization

processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8)

Formation of

uroliths follows crystallization rules. Mg ion reduces the rate of

superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and

accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society

76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica

Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3)

456-500, 1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal

layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium

on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

------------ --------- --------- --------- --------- --------- -

----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

> >

> > Alzheimer's drugs cause brain damage and actually worsen memory loss

> > Wednesday, April 21, 2010 by: S. L. Baker

> >

> > _http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html_

(http://www.naturaln ews.com/028622_ Alzheimers_ brain_damage. html)

> >

>

[Guest guest]

I have all the waste water sent out via the waste tube to water my non-edible

plants just outside the kitchen instead of sending it down the drain.

Ten years plus and the plants seem to be thiving.

________________________________

From: D. Mindock <oceanpine@...>

Longevity

Sent: Sun, April 25, 2010 8:30:35 AM

Subject: Re: Re: Alzheimer's drugs cause brain damage

 

I read somewhere that reverse osmosis is wasteful of water. Two gallons go down

the drain for each

gallon of filtered water produced. True, tap water is cheap, but it is likely

undervalued, even with the

fluoride in it and who knows what else. Distilling water takes a lot of energy.

I believe that the six

stage filter I use by Crystal Quest which removes fluoride might be the cheapest

way to arrive at

clean water. The good minerals like magnesium aren't affected. All the nasty

ones like lead and cadmium

are filtered out. All the POVs, PCBs, etc are filtered out. I used to use the

Crystal Quest and then follow

with the distillation but decided it was overkill. WRT the Crystal Quest, one

stage is totally dedicated to

removing the fluoride. They do have other filters that don't remove the

fluoride, I guess for the peeps that

still believe fluoride is healthful, if they only knew!

Peace, D Mindock

Yes, but you can add them back with a very inexpensive mineral mixture.

Re: Alzheimer's drugs cause brain damage

Longevity@grou ps.com

Date: Thursday, April 22, 2010, 2:15 PM

Hello.

It would be wonderful if magnesium did protect from fluoride, but from

what I read, fluoride is an magnesium antagonist - the toxic effects of

fluoride ion plays a key role in acute Magnesium deficiency. Here is an

article about fluoride aned magnesium.

FLUORIDE-MAGNESIUM INTERACTION (Guest Editorial)

_http://www.mgwater. com/fl2.shtml_ (http://www.mgwater. com/fl2.shtml)

by A Machoy-Mokrzynska (Institute of Pharmacology and Toxicology,

Pomeranian Medical Academy, Szczecin, Poland)

Fluoride (J. of the International Society for Fluoride Research), Vol. 28

No. 4; November, 1995, pp 175-177

It has now been fifteen years since Marier drew attention to the

significance of magnesium in biological interaction with fluorides.(1) The

toxic

effect of fluoride ion plays a key role in acute Mg deficiency. The amount

of

F- assimilated by living organisms constantly increases, and Mg absorption

diminishes as a consequence of progressively advancing industrialization.

Marier gives examples of such retention of both elements in plants (e.g.

in

pine and tomatoes) and in animals, for instance in bone tissue, blood and

kidneys, with the last being thought as the most probable place of Mg-F-

interaction. (1) Now, further facts have been observed, which throw a new

light

on the effects of Mg-F- interaction.

The significance and distribution of Mg in living organisms are widely

known and described in textbooks.(2) Fluoride ion clearly interferes with

the

biological activity of magnesium ion.(3) Present-day Mg deficiencies in

humans are the result of intensive expulsion of this element (e.g. under

the

influence of extensive drinking of alcoholic beverages) or reduced Mg

content in the diet, caused, for example, by inappropriate agricultural

practices

or effects of ecotoxins.(4)

One of the prime locations of possible F- and Mg interactions is the

intestines. The increased F-supply reduces intestinal Mg resorption, owing

to

high chemical affinity of both elements and production of MgF+ and

MgF2.(1)

However, there are many facts to be considered, since there is a common

mechanism of transportation of both these elements through the intestinal

walls. Distinct F--Mg interaction is also observed in other cells and

tissues.

Mg deficiency in plants may limit synthesis of chlorophyll, on which

photosynthesis depends. Therefore, supplementation of Mg protects plants

against

toxic effects of fluoride compounds.(1) Mg deficiency in animals reduces

production of energy, relevant to the Mg-ATP system. Reduction of ATP

levels

affects in an unfavourable way many metabolic processes connected with the

action of ATP (eg, metabolism of carbohydrates, proteins, nucleic acids,

lipids, and active transport).

The role of Mg and F- ions in enzymology is also well known.

Magnesium-dependant enzymes compose the biggest group in enzyme

systematics. Magnesium

is the activator of more than 300 enzymes, while fluorine is known as

their

inhibitor, although the activity of some enzymes is known to be increased

by fluorine.(5) In general, Mg-F- interactions most frequently decrease

enzymatic activity.(6) The greatest practical significance of Mg-F-

interaction

however, seems to be in processes of bone and tooth mineralization, and in

the formation of uroliths.(7, 8)

In bone tissue magnesium stimulates the transformation of immature

(amorphic) bone into a more crystalic form. Owing to the translocation of

Mg into

mineral tissue, bone elasticity increases to help prevent fractures. Rats

on diet poor in Mg display significantly higher content of F- in femurs

and

molars. This is undoubtedly related to the assimilability of both

elements.

Since bioavailability of Mg and F- depends on their mutual ratio in the

diet,(9) a low-magnesium diet distinctly increases F- absorption in the

intestines.

Taking into account the mineralization of bone tissue, one also cannot

ignore the role of calcium. The basic inorganic compound of bones is

hydroxyapatite, containing calcium phosphate. The far-reaching antagonism

between

magnesium and calcium affects not only their different distribution in

tissues, but also their mutual dislodging from cells. For example,

magnesium

favours blocking of calcium channels, disturbs oxidative phosphorylation,

intensifies bone decalcification and increases muscle-cell diastole, while

calcium intensifies contraction. On the other hand, hypercalcemia enhances

Mg

loss or magnesiuria. (10)

Mg-F- interaction processes relating to enamel and its effect on caries

have also been investigated. Fluoride ion affects enamel hardening (11,

12)

and prevents its annealing, but this effect diminishes after

administration

of Mg. Magnesium alone does not visibly affect tooth plaque, erosive

enamel

damage, or the course of caries, but Mg and F- administered jointly

influence enamel hardening and reduce caries significantly, as

demonstrated in

rats.(13) In interactions of F- with Mg and Ca, it should be stressed that

it

is calcium rather than magnesium that intensifies mineralization

processes.

Urolith formation is considered to be pathological. Mineral content

analysis of uroliths shows that they always contain Mg and F- (besides

phosphates, calcium and other inorganic and organic components). (8)

Formation of

uroliths follows crystallization rules. Mg ion reduces the rate of

superficial

crystal nuclei formation, whereas F- ion accelerates the process. The

former reduces and the latter accelerates growth of calcium phosphate

crystals.(7) In the formation of uroliths, calcium is the promotor, and

magnesium

plays the role of the inhibitor.

It also should be pointed out that uroliths always contain more Ca than

Mg. Fluoride on the other hand, favours formation of uroliths and

accelerates

their production.( 8)

In summary, it can be stated that in intoxication with fluorine compounds,

magnesium plays a protective role by countering and reducing the toxic

effects of F-.

------------ --------- --------- --------- --------- --------- -

----

References:

1 Marier J R. Observations and implications of the (Mg F) interrelations

in bio-systems: a review and comments on magnesium intake and fluoride

intake in the modern-day world. Proceedings of the Finnish Dental Society

76.

82-92, 93-102, 1980. (Abstracted in Fluoride 14, 142 1981).

2 Durlach J. Le magnesium en pratique clinique. Editions Medicales

Internationales. Paris 1991.

3 Guminska M. The effect of magnesium on metabolism in living organisms

and medical consequences of its deficiency in man. Folia Medica

Cracoviensia

26 1-2, 5-28, 1985.

4 Markiewicz J. Environmental factors decreasing magnesium content in

alimentary chain. Folia Medica Cracoviensia 26 1-2, 5-28, 1985.

5 Strochkova L S, Zhavoronkov A A. Fluroide as an activator of enzymatic

systems. Fluoride 16, 181-186 1983.

6 Chlubek D, Machoy Z. Significance of the effect of fluorine dose on

enzymes activity in vivo and in vitro studies. Bromatologia i Chemia

Toksykologiczna 22 3-4, 235-242, 1989.

7 Okazaki M. Mg2+-F- interaction during hydroxyapatite formation.

Magnesium 6 (6) 296-301, 1987.

8 Machoy P, Bober J. Fluorine-constant component of urinary calculi,

Environmental Sciences 2 1 11-15, 1993.

9 Cerklewski F L. Influence of dietary magnesium on fluoride

bioavailability in the rat. American Insitute of Nutrition 117 (3)

456-500, 1987.

10 Machoy Z. Biochemical mechanisms of fluorine compounds action. Folia

Medica Cracoviensia 28 1-2, 61-81, 1987.

11 Collys K, Slop D, Coomans D. Interaction of magnesium and fluoride in

the rehardening and acid resistance of surface-softened bovine enamel in

vitro. Magnesium Trace Element 9 (1) 47- 53, 1990.

12 Luoma A R, Luoma H, Raisanen J, Hausen H. Effect of magnesium and

fluoride on the fermentative dissolution of enamel by a streptococcal

layer as

measured by mircrohardness tester and a proton probe microanalysis. Caries

Research 17 430-438, 1983.

13 Sorvari R, Koskinen-Kainulaine n M, Sorvari T, Luoma H. Effect of a

sports drink mixture with and without addition of fluoride and magnesium

on

plaque formation, dental caries and general health of rats. Scandinavian

Journal of Dental Research 94 483-490, 1986.

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----

FLUORIDE: published by the International Society for Fluoride Research

Editorial Office: 81A Landscape Road, Mt Eden, Auckland 4, NZ Subscription

Rate: $40. U.S. Funds per year (quarterly publication)

blessings

Shan

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