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Is cancer a man-made

disease?_http://ca.news./s/canada/101016/canada/is_cancer_a_man_ma\

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Is the common nature of cancer worldwide purely a man-made phenomenon?

That is what some researchers now suggest.

Still, other specialists in cancer and in human fossils have strong doubts

about this notion.

Cancer is a leading cause of death worldwide, accounting for roughly one

in eight of all deaths in 2004, according to the World Health Organization.

However, scientists have only found one case of the disease in

investigations of hundreds of Egyptian mummies, researcher lie at the

University of Manchester in England said in a statement. (The researchers did

not

reply to repeated queries made via phone and e-mail.)

The rarity of cancer in mummies suggests it was scarce in antiquity, and

**that cancer-causing factors are limited to societies affected by modern

industrialization,** researcher Zimmerman at Villanova University in

Pennsylvania said in a statement. **In an ancient society lacking surgical

intervention, evidence of cancer should remain in all cases.**

Zimmerman was the first to diagnose cancer in an Egyptian mummy by

analyzing its tissues on a microscopic level, identifying rectal cancer in an

unnamed mummy who had lived in the Dakhleh Oasis during the Ptolemaic period

1,600 to 1,800 years ago.

and Zimmerman also analyzed ancient literature from Egypt and Greece

for hints of cancer, as well as medical studies of human and animal

remains going back to the age of dinosaurs. They suggested evidence of cancer in

animal fossils, non-human primates and early humans was scarce, with a few

dozen uncertain examples. As they analyzed ancient literature, they did not

find descriptions of operations for breast and other cancers until the 17th

century, and the first reports in the scientific literature of distinctive

tumors have only occurred in the past 200 years, such as scrotal cancer in

chimney sweepers in 1775, nasal cancer in snuff users in 1761 and

Hodgkin's disease in 1832.

One possible reason cancers might have been comparatively rare in antiquity

is that the short life span of individuals back then precluded the

development of the disease. Still, the researchers did note some people in

ancient

Egypt and Greece did live long enough to develop such diseases as

atherosclerosis, Paget's disease of bone, and osteoporosis.

and Zimmerman therefore argue that cancer nowadays is largely caused

by man-made environmental factors such as pollution and diet. They

detailed their findings in the October issue of the journal Nature Reviews

Cancer.

**In industrialized societies, cancer is second only to cardiovascular

disease as a cause of death, but in ancient times, it was extremely rare,**

said in a statement. **There is nothing in the natural environment that

can cause cancer.**

Despite that statement, dinosaurs did develop cancer well before humans

were on the scene. Also, others argue the short life spans of antiquity could

be a profoundly effective reason as to why cancer might have been rare then.

**Cancer is very rare in modern societies in humans under age 30,**

oncologist Dr. Glaspy at UCLA's Jonsson Comprehensive Cancer Center told

LiveScience. ** In ancient times, people rarely lived to be much older than

that. So cancer was rare. The 'sin' of modern societies is having people live

to be much older.**

Another concern when examining the fossil record is that skeletal remains

might not preserve cancers very well. **To see cancers with the skeletal

record, you really have to have a tumor that's affecting bone,**

paleoanthropologist Hawks at the University of Wisconsin at Madison said

in a phone

interview. " Although there might be few confirmed diagnoses of tumors in

bones, it's because cancer is a difficult diagnosis to make from bone.**

Hawks did note that modern lifestyles could certainly lead to much higher

rates of cancer than in the past, but not necessarily due to pollution.

**When it comes to cancers such as breast cancer, we know the age that a

woman first has children or not makes a lot of difference in whether they get

breast cancer, and back then people had children early, which would have

put them into a lower-risk category,** Hawks said.

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