Good article on mechanism by which mycotoxins may cause depression- Please read

[Guest guest]

There is a good article at

http://molinterv.aspetjournals.org/cgi/content/full/3/8/441

that everyone here should read..

_____cut here_______

*A neurogenic theory of depression gains

momentum.*<http://molinterv.aspetjournals.org/cgi/content/full/3/8/441>

*

RM*<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed & cmd=Search & itool=Pub\

Med_Abstract & term=%22+RM%22%5BAuthor%5D>,

*

DA*<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed & cmd=Search & itool=Pub\

Med_Abstract & term=%22+DA%22%5BAuthor%5D>

..

Department of Neuroscience, The Chicago Medical School North Chicago, IL,

USA.

The rate of adult neurogenesis fluctuates in response to several

environmental factors. Chronic stress, which can lead to neuronal apoptosis

and dendritic atrophy, certainly affects the overall rate of neurogenesis in

the adult brain. Depression, which arises from several causes, including

chronically stressful situations, is known to correlate with altered

hippocampal morphology. But is the link between depression and neuronal

regeneration merely coincidental? Recent studies indicate that ingestion of

antidepressants leads to increased neurogenesis in the hippocampus. However,

the hippocampus is generally thought important for learning and memory-not

for " mood " state-thus, there is much more to the story that requires

clarification. Also, caveats abound in the interpretation of neurogenesis in

the amelioration of depression; nonetheless, these results are quite

intriguing and might point to better design and prediction of new-generation

antidepressants.

PMID: 14993452 [PubMed - indexed for MEDLINE]

____end abstract_____

My logic goes like this:

Mycotoxicosis from stachybotrys and perhaps other mycotoxins can cause an

inability in the body to create new cells by inhibiting protein synthesis.

In addition to preventing other natural repair processes, like those in the

joints, eyes, nose, etc, this inhibition is probably the mechanism by which

mycotoxins prevent long term memories from forming during sleep - the period

during which the body turns a days memories into physical brain

connections..

This inhibits nuts and bolts integration of new learning, ('long term

potentiation') - it also seems to cause depressive illness in many..

The theory described in the article above would explain all this...