Guest guest Posted December 3, 2006 Report Share Posted December 3, 2006 , Your case seems fascinating and has had no responses so I discussed it with some other docs. This is what they said.... let me know if any of it fits. Brad i am really reaching here but estrogen dominance could cause increased ldl and indirectly tsh elevations, the estrogen dominance could have been triggered by the resolution of her lead toxicity. lead inhibits aromatase activity which is needed for production of estrogen and lead may inhibit estrogen receptor activity. just my guess tim Note: forwarded message attached. Have a burning question? Go to Answers and get answers from real people who know. The LDL jump is likely the a direct effect of the thyroid level so the real question is what happened to the thyroid. Possibilities: 1. Increased dietary gluten intake since there appears to be a significant association between gluten sensitivity and Hashimoto's thyroiditis. Does she have an elevated anti-TPO Ab level? 2. Increased soy intake. Much of the soy sold in the U.S. is the highly heat processed dregs of what's left over from pressing vegetable oil and can be quite toxic to the thyroid 3. Change in hormone status as Tim alluded to. Not so sure in a 70 y.o. unless has had a change in HRT therapy. Progesterone deficiency can induce a degree of hypothyroidism 4. Other metal exposure, e.g. Hg. New fillings or dental work? 5. Change in nutritional status. Zn and/or Se deficiencies will affect T4 to T3 conversion 6. New or increased stress. In my practice this is almost always a, if not THE, factor when someone's condition takes a sudden turn. Hope this helps. If nothing shows up, it might be better to just go ahead and start Armour(or increase her dose if she is already on) to get the TSH between 1 and 2. The lipid situation should respond in kind. Klein > " I am treating a 70 year old woman for suspicious looking precancerous > cell in her bladder and high urine lead levels. After several months, > her lead levels returned to normal and examinations of her bladder > revealed no abnormal cells. But now her TSH skyrocketed from 2.5 to 4.7 > and her LDL rose from 135 to 247. Her Cholesterol/ HDL ratio is 7.6. She > has been on 1.0 grain of Armour thyroid for about a year. I have been > monitoring her labs regularly. This spike in values was unexpected and > sudden. > > She also has tachycardia which she has had her whole life (and HTN). > She is taking Niasafe, Gugul-lipid, trace minerals, zinc, Homeopathic > UNDA #'s 8, 33, 203 (on these her tachycardia dropped from 100 bpm to > 80 bpm), magnesium taurate and fish oil. > > Any ideas on why the TSH and LDL jumped so high? " > > > Blessings, > Brad > > > Dr Bradley West (ND) > PO Box 1434 > Felton, CA 95018 > > Do not go where the path may lead, go instead where there is no path > and leave a trail. > - Ralph Waldo Emerson > > > > > > > > > > > > > > > > > --------------------------------- > Everyone is raving about the all-new beta. Quote Link to comment Share on other sites More sharing options...
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