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Modafinil Improves Cognition & response inhibition in ADHD

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Hi:

I do a lot of sustained mental work and it has helped with focus,

energy and endurance. I also notice that I do a bit better at

aerobic exercise, which I didn't expect. Interestingly, I also heard

that one Olympic star was eliminated for its use. There are several

studies that show it works better than SSRIs and other drugs for

depression. It helps with ADHD and unlike the normal stimulants, it

is not addictive and does not have most of their side effects. On

Ritalin, for example, mental performance is reduced, whereas on

Modafinil, it is

improved. <http://www.breggin.com/ritalin.html>Ritalin has many side

effects and can be addictive. In some mental tests that measure time

of response, Modafinil caused response times to increase, but

accuracy improved. It is thought that one is more analytical on

Modafinil, than without it. It is even being tested with

schizophrenia and although it does not affect delusions, it helps

schizophrenics cope in the world, like keeping jobs, because most

schizophrenics have learned to sufficiently ignore their delusions to

cope, but the other effects of the disease keep their abilities to

'think straight' off-track. This information mostly came from a

conference video I saw from Oxford University from research being

carried out at

<http://www.admin.cam.ac.uk/news/press/dpp/2002110501>Cambridge

University the link describes some of that.

Here's a short excerpt:

le , from the Department of Psychiatry at the University

of Cambridge, took a group of 60 healthy young males and tested them

using touch-sensitive computer screens and easy-to-understand

'computer games' after they had received either a dummy tablet

(placebo) or Modafinil.

" In the study, the volunteers given Modafinil performed significantly

better at neuropsychological tests involving short-term memory and

showed less impulsive responding and an increased tendency to reflect

on the tasks they were given, " she said.

" The research suggests that it may at last be possible to help

patients with neuropsychiatric disorders, such as Attention Deficit

Hyperactivity Disorder (ADHD), who suffer from selective impairments

in memory, problem-solving and planning. "

At 12:27 PM 8/14/2006, you wrote:

>:

>

>Well, I guess we could all use a piece of that action.

>

>Did you have any specific problems that you were trying to address?

>If so, what relief did you get?

>

>(I realize that I could be prying into something that you prefer not

>discuss here. If so, do not respond)

>

>Thanks, Jim

>

> Brown wrote:

>

> > Hi:

> >

> > Wakefulness, improved mental focus and cognition.

> >

> >

> >

> > At 09:42 AM 8/14/2006, you wrote:

> >

> > >:

> > >

> > >I guess I missed the earlier post. What do you take it for and what

> > >effects have you

> > >observed ?

> > >

> > >Jim

> > >

> > > Brown wrote:

> > >

> > > > Hi:

> > > >

> > > > I've easily bought Modafinil from international sources. It works

> > > > well. It is not addictive at all. It is probably not very liver

> > > > toxic as I couldn't find much about that beyond warnings. I posted a

> > > > source in my previous post. I've not tried Adrafinil. I've been

> > > > using Modafinil at 100 mg for about 2 weeks with some days off.

> > > >

> > > >

> > > >

> > > > At 09:46 PM 8/13/2006, you wrote:

> > > >

> > > > >On Sunday 13 August 2006 9:37 pm, Apricot85 wrote:

> > > > > > Do you (or anyone) use it only for selected occasions? Or more

> > > > > > regularly? Have you (or anyone) tried both adrafinil and

> > > > monofidil? And

> > > > > > if so have you perceived any difference between the two? I

> > have taken

> > > > > > adrafinil & liked the wakefulness ... but I've cut it out with

> > a fear

> > > > > > for liver.

> > > > >

> > > > >I've tried adrafinil several times and got no response. It is

> > > > available from

> > > > >international sources. Modafinil requires a prescription in the

> > US and is

> > > > >scheduled in such a way that it's more difficult to import and many

> > > > >international sites won't ship to US destinations or won't sell it at

> > > > all.

> > > > >

> > > > >As to liver problems, they are rare and I believe much rarer than for

> > > > example

> > > > >using statin " cholesterol lowering " drugs. One can always get

> > your liver

> > > > >checked. The Life Extension Foundation offers complete

> > > > CBC/CMP+cholesterol

> > > > >test for $35.

> > > > >

> > > > >--

> > > > >

> > > > >Steve -

> > > >

> > >

> >

>

<mailto:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net><mailt\

o:dudescholar2%40basicmail.net>dudescholar2@...

>

> > <mailto:dudescholar2%40basicmail.net>

> > >

> > > > <mailto:dudescholar2%40basicmail.net>

> > > > >

> > > > > " Convictions are more dangerous enemies of truth than lies. "

> > > > >--Friedrich Nietzsche

> > > > >

> > > > >

> > > >

> > > >

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Share on other sites

Hi:

I do a lot of sustained mental work and it has helped with focus,

energy and endurance. I also notice that I do a bit better at

aerobic exercise, which I didn't expect. Interestingly, I also heard

that one Olympic star was eliminated for its use. There are several

studies that show it works better than SSRIs and other drugs for

depression. It helps with ADHD and unlike the normal stimulants, it

is not addictive and does not have most of their side effects. On

Ritalin, for example, mental performance is reduced, whereas on

Modafinil, it is

improved. <http://www.breggin.com/ritalin.html>Ritalin has many side

effects and can be addictive. In some mental tests that measure time

of response, Modafinil caused response times to increase, but

accuracy improved. It is thought that one is more analytical on

Modafinil, than without it. It is even being tested with

schizophrenia and although it does not affect delusions, it helps

schizophrenics cope in the world, like keeping jobs, because most

schizophrenics have learned to sufficiently ignore their delusions to

cope, but the other effects of the disease keep their abilities to

'think straight' off-track. This information mostly came from a

conference video I saw from Oxford University from research being

carried out at

<http://www.admin.cam.ac.uk/news/press/dpp/2002110501>Cambridge

University the link describes some of that.

Here's a short excerpt:

le , from the Department of Psychiatry at the University

of Cambridge, took a group of 60 healthy young males and tested them

using touch-sensitive computer screens and easy-to-understand

'computer games' after they had received either a dummy tablet

(placebo) or Modafinil.

" In the study, the volunteers given Modafinil performed significantly

better at neuropsychological tests involving short-term memory and

showed less impulsive responding and an increased tendency to reflect

on the tasks they were given, " she said.

" The research suggests that it may at last be possible to help

patients with neuropsychiatric disorders, such as Attention Deficit

Hyperactivity Disorder (ADHD), who suffer from selective impairments

in memory, problem-solving and planning. "

At 12:27 PM 8/14/2006, you wrote:

>:

>

>Well, I guess we could all use a piece of that action.

>

>Did you have any specific problems that you were trying to address?

>If so, what relief did you get?

>

>(I realize that I could be prying into something that you prefer not

>discuss here. If so, do not respond)

>

>Thanks, Jim

>

> Brown wrote:

>

> > Hi:

> >

> > Wakefulness, improved mental focus and cognition.

> >

> >

> >

> > At 09:42 AM 8/14/2006, you wrote:

> >

> > >:

> > >

> > >I guess I missed the earlier post. What do you take it for and what

> > >effects have you

> > >observed ?

> > >

> > >Jim

> > >

> > > Brown wrote:

> > >

> > > > Hi:

> > > >

> > > > I've easily bought Modafinil from international sources. It works

> > > > well. It is not addictive at all. It is probably not very liver

> > > > toxic as I couldn't find much about that beyond warnings. I posted a

> > > > source in my previous post. I've not tried Adrafinil. I've been

> > > > using Modafinil at 100 mg for about 2 weeks with some days off.

> > > >

> > > >

> > > >

> > > > At 09:46 PM 8/13/2006, you wrote:

> > > >

> > > > >On Sunday 13 August 2006 9:37 pm, Apricot85 wrote:

> > > > > > Do you (or anyone) use it only for selected occasions? Or more

> > > > > > regularly? Have you (or anyone) tried both adrafinil and

> > > > monofidil? And

> > > > > > if so have you perceived any difference between the two? I

> > have taken

> > > > > > adrafinil & liked the wakefulness ... but I've cut it out with

> > a fear

> > > > > > for liver.

> > > > >

> > > > >I've tried adrafinil several times and got no response. It is

> > > > available from

> > > > >international sources. Modafinil requires a prescription in the

> > US and is

> > > > >scheduled in such a way that it's more difficult to import and many

> > > > >international sites won't ship to US destinations or won't sell it at

> > > > all.

> > > > >

> > > > >As to liver problems, they are rare and I believe much rarer than for

> > > > example

> > > > >using statin " cholesterol lowering " drugs. One can always get

> > your liver

> > > > >checked. The Life Extension Foundation offers complete

> > > > CBC/CMP+cholesterol

> > > > >test for $35.

> > > > >

> > > > >--

> > > > >

> > > > >Steve -

> > > >

> > >

> >

>

<mailto:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net><mailt\

o:dudescholar2%40basicmail.net>dudescholar2@...

>

> > <mailto:dudescholar2%40basicmail.net>

> > >

> > > > <mailto:dudescholar2%40basicmail.net>

> > > > >

> > > > > " Convictions are more dangerous enemies of truth than lies. "

> > > > >--Friedrich Nietzsche

> > > > >

> > > > >

> > > >

> > > >

Link to comment
Share on other sites

I have ADHD and I consider it to be quite

debilitating. I used to be an artist but I just can't

focus anymore. It takes me hours to complete even

routine responsibilities. I was ready to order the

Modafinil after the first post but have a few

questions. I am 58 and am being treated for Bi-Polar 2

disorder (lamictal and zoloft). I mention my age

because my memory is poor, tho that may be a

consequence of the meds that I am taking or the fact

that I am also dissociative.

I started a pretty intensive self proscribed vitamin

program a couple of months ago, including Cognitex

from LEF. I have ordered some deprenyl from IAS and am

also planning to add some of the " smart " nutes from

their site.

Does anyone know if Modafinil would be

contraindicated? No point in my talking to my doctor.

__________________________________________________

Link to comment
Share on other sites

Hi:

In some of the Cambridge studies, and other studies I saw on Medline

carried out by the Veteran's Administration, UCLA (Mark Frye, MD:

Associate Director, UCLA Mood Disorders Research Program, Director,

Bipolar Research Program, Associate Professor of Psychiatry) and

others, people with bipolar disorder have been given Modafinil, often

with great improvement. From my understanding the studies initially

included leaving the patients on their existing meds, which

varied. Although bipolar disorder has not been as extensively

studied as narcolepsy, depression, schizophrenia and post-stroke

depression, it seems to help those with bipolar disorder, especially

if there is hypersomnia. Also, I am certain that there is no

significant interaction with Zoloft to contraindicate Modafinil, and

I could find none on Lamictal. I take Deprenyl and Cognitex with no

adverse reactions. Just in case, I would proceed with some initial

caution. Start with a small dose and work up, perhaps. I find that

more than 100 mg per day, taken in the morning only, is not necessary

for me. Some users take a lot more, but the usual dose is 200mg per

day. It comes in 100mg and 200mg tablets. Nevertheless it is a

very, very safe drug, in terms of toxicity and adverse reaction to

overdose - see below (from rxlist.com).

----------

OVERDOSE

In clinical trials, a total of 151 protocol-specified doses ranging

from 1000 to 1600 mg/day (5 to 8 times the recommended daily dose of

200 mg) have been administered to 32 subjects, including 13 subjects

who received doses of 1000 or 1200 mg/day for 7 to 21 consecutive

days. In addition, several intentional acute overdoses occurred; the

two largest being 4500 mg and 4000 mg taken by two subjects

participating in foreign depression studies. None of these study

subjects experienced any unexpected or life-threatening effects.

Adverse experiences that were reported at these doses included

excitation or agitation, insomnia, and slight or moderate elevations

in hemodynamic parameters. Other observed high-dose effects in

clinical studies have included anxiety, irritability, aggressiveness,

confusion, nervousness, tremor, palpitations, sleep disturbances,

nausea, diarrhea and decreased prothrombin time.

From post-marketing experience, there have been no reports of fatal

overdoses involving modafinil alone (doses up to 12 grams). Overdoses

involving multiple drugs, including modafinil, have resulted in fatal

outcomes. Symptoms most often accompanying modafinil overdose, alone

or in combination with other drugs have included: insomnia; central

nervous system symptoms such as restlessness, disorientation,

confusion, excitation and hallucination; digestive changes such as

nausea and diarrhea; and cardiovascular changes such as tachycardia,

bradycardia, hypertension and chest pain.

Cases of accidental ingestion/overdose have been reported in children

as young as 11 months of age. The highest reported accidental

ingestion on a mg/kg basis occurred in a three-year-old boy who

ingested 800-1000 mg (50-63 mg/kg) of modafinil. The child remained

stable. The symptoms associated with overdose in children were

similar to those observed in adults.

Overdose Management

No specific antidote to the toxic effects of modafinil overdose has

been identified to date. Such overdoses should be managed with

primarily supportive care, including cardiovascular monitoring. If

there are no contraindications, induced emesis or gastric lavage

should be considered. There are no data to suggest the utility of

dialysis or urinary acidification or alkalinization in enhancing drug

elimination. The physician should consider contacting a

poison-control center on the treatment of any overdose.

CONTRAINDICATIONS

PROVIGIL is contraindicated in patients with known hypersensitivity

to modafinil.

----------

I sure hope that this helps. If you decide to take it, please let

all of us know how it went.

At 03:48 PM 8/14/2006, you wrote:

>I have ADHD and I consider it to be quite

>debilitating. I used to be an artist but I just can't

>focus anymore. It takes me hours to complete even

>routine responsibilities. I was ready to order the

>Modafinil after the first post but have a few

>questions. I am 58 and am being treated for Bi-Polar 2

>disorder (lamictal and zoloft). I mention my age

>because my memory is poor, tho that may be a

>consequence of the meds that I am taking or the fact

>that I am also dissociative.

>

>I started a pretty intensive self proscribed vitamin

>program a couple of months ago, including Cognitex

>from LEF. I have ordered some deprenyl from IAS and am

>also planning to add some of the " smart " nutes from

>their site.

>

>Does anyone know if Modafinil would be

>contraindicated? No point in my talking to my doctor.

>

>__________________________________________________

>

Link to comment
Share on other sites

Hi:

In some of the Cambridge studies, and other studies I saw on Medline

carried out by the Veteran's Administration, UCLA (Mark Frye, MD:

Associate Director, UCLA Mood Disorders Research Program, Director,

Bipolar Research Program, Associate Professor of Psychiatry) and

others, people with bipolar disorder have been given Modafinil, often

with great improvement. From my understanding the studies initially

included leaving the patients on their existing meds, which

varied. Although bipolar disorder has not been as extensively

studied as narcolepsy, depression, schizophrenia and post-stroke

depression, it seems to help those with bipolar disorder, especially

if there is hypersomnia. Also, I am certain that there is no

significant interaction with Zoloft to contraindicate Modafinil, and

I could find none on Lamictal. I take Deprenyl and Cognitex with no

adverse reactions. Just in case, I would proceed with some initial

caution. Start with a small dose and work up, perhaps. I find that

more than 100 mg per day, taken in the morning only, is not necessary

for me. Some users take a lot more, but the usual dose is 200mg per

day. It comes in 100mg and 200mg tablets. Nevertheless it is a

very, very safe drug, in terms of toxicity and adverse reaction to

overdose - see below (from rxlist.com).

----------

OVERDOSE

In clinical trials, a total of 151 protocol-specified doses ranging

from 1000 to 1600 mg/day (5 to 8 times the recommended daily dose of

200 mg) have been administered to 32 subjects, including 13 subjects

who received doses of 1000 or 1200 mg/day for 7 to 21 consecutive

days. In addition, several intentional acute overdoses occurred; the

two largest being 4500 mg and 4000 mg taken by two subjects

participating in foreign depression studies. None of these study

subjects experienced any unexpected or life-threatening effects.

Adverse experiences that were reported at these doses included

excitation or agitation, insomnia, and slight or moderate elevations

in hemodynamic parameters. Other observed high-dose effects in

clinical studies have included anxiety, irritability, aggressiveness,

confusion, nervousness, tremor, palpitations, sleep disturbances,

nausea, diarrhea and decreased prothrombin time.

From post-marketing experience, there have been no reports of fatal

overdoses involving modafinil alone (doses up to 12 grams). Overdoses

involving multiple drugs, including modafinil, have resulted in fatal

outcomes. Symptoms most often accompanying modafinil overdose, alone

or in combination with other drugs have included: insomnia; central

nervous system symptoms such as restlessness, disorientation,

confusion, excitation and hallucination; digestive changes such as

nausea and diarrhea; and cardiovascular changes such as tachycardia,

bradycardia, hypertension and chest pain.

Cases of accidental ingestion/overdose have been reported in children

as young as 11 months of age. The highest reported accidental

ingestion on a mg/kg basis occurred in a three-year-old boy who

ingested 800-1000 mg (50-63 mg/kg) of modafinil. The child remained

stable. The symptoms associated with overdose in children were

similar to those observed in adults.

Overdose Management

No specific antidote to the toxic effects of modafinil overdose has

been identified to date. Such overdoses should be managed with

primarily supportive care, including cardiovascular monitoring. If

there are no contraindications, induced emesis or gastric lavage

should be considered. There are no data to suggest the utility of

dialysis or urinary acidification or alkalinization in enhancing drug

elimination. The physician should consider contacting a

poison-control center on the treatment of any overdose.

CONTRAINDICATIONS

PROVIGIL is contraindicated in patients with known hypersensitivity

to modafinil.

----------

I sure hope that this helps. If you decide to take it, please let

all of us know how it went.

At 03:48 PM 8/14/2006, you wrote:

>I have ADHD and I consider it to be quite

>debilitating. I used to be an artist but I just can't

>focus anymore. It takes me hours to complete even

>routine responsibilities. I was ready to order the

>Modafinil after the first post but have a few

>questions. I am 58 and am being treated for Bi-Polar 2

>disorder (lamictal and zoloft). I mention my age

>because my memory is poor, tho that may be a

>consequence of the meds that I am taking or the fact

>that I am also dissociative.

>

>I started a pretty intensive self proscribed vitamin

>program a couple of months ago, including Cognitex

>from LEF. I have ordered some deprenyl from IAS and am

>also planning to add some of the " smart " nutes from

>their site.

>

>Does anyone know if Modafinil would be

>contraindicated? No point in my talking to my doctor.

>

>__________________________________________________

>

Link to comment
Share on other sites

Hi Dave:

Modafinil works well for me. I've tried Piracetam up to 800 mg, but

not with an equal dose of Acetyl-L-Carnitine. It certainly helps,

but it wears off much faster than Modafinil and doesn't provide the

wakefulness. Modafinil also definitely improves both my long-term

and short-term memory. I drink much less coffee on Modafinil, so

that is pretty good too. Coffee is small doses is good for you, but

in larger doses, depletes the minerals in the body and can be bad for

the kidneys. The only thing I don't like about Modafinil is that it

wears off so slowly. On the days I decide to use it, when I need to

work intensely, I take 100 mg (1/2 tablet) when I first get up in the

morning and when I should be going to bed, 16 to 18 hours later, it

is still affecting me, making it more difficult to sleep

initially. But I like the fact that in between, there is no lack of

strongly-focused attention.

I'm going to try the doses you recommend, the next time I get some

Piracetam. I take Acetyl-L-Carnitine all the time. Do you buy

Piracetam in bulk?

Thanks for the information.

At 08:06 PM 8/18/2006, you wrote:

>I've tried Modafinil and personally feel it's a crappy smart drug,

>although it's good if you *need* to stay awake longer than caffeine will

>allow. 1000mg of Acetyl-L-Carnitine with 1000 mg of Piracitam does a

>lot more for me IMO.

>

>Jim wrote:

> >

> >

> > :

> >

> > Well, I guess we could all use a piece of that action.

> >

> > Did you have any specific problems that you were trying to address?

> > If so, what relief did you get?

> >

> > (I realize that I could be prying into something that you prefer not

> > discuss here. If so, do not respond)

> >

> > Thanks, Jim

> >

> > Brown wrote:

> >

> > > Hi:

> > >

> > > Wakefulness, improved mental focus and cognition.

> > >

> > >

> > >

> > > At 09:42 AM 8/14/2006, you wrote:

> > >

> > > >:

> > > >

> > > >I guess I missed the earlier post. What do you take it for and what

> > > >effects have you

> > > >observed ?

> > > >

> > > >Jim

> > > >

> > > > Brown wrote:

> > > >

> > > > > Hi:

> > > > >

> > > > > I've easily bought Modafinil from international sources. It works

> > > > > well. It is not addictive at all. It is probably not very liver

> > > > > toxic as I couldn't find much about that beyond warnings. I posted a

> > > > > source in my previous post. I've not tried Adrafinil. I've been

> > > > > using Modafinil at 100 mg for about 2 weeks with some days off.

> > > > >

> > > > >

> > > > >

> > > > > At 09:46 PM 8/13/2006, you wrote:

> > > > >

> > > > > >On Sunday 13 August 2006 9:37 pm, Apricot85 wrote:

> > > > > > > Do you (or anyone) use it only for selected occasions? Or more

> > > > > > > regularly? Have you (or anyone) tried both adrafinil and

> > > > > monofidil? And

> > > > > > > if so have you perceived any difference between the two? I

> > > have taken

> > > > > > > adrafinil & liked the wakefulness ... but I've cut it out with

> > > a fear

> > > > > > > for liver.

> > > > > >

> > > > > >I've tried adrafinil several times and got no response. It is

> > > > > available from

> > > > > >international sources. Modafinil requires a prescription in the

> > > US and is

> > > > > >scheduled in such a way that it's more difficult to import and many

> > > > > >international sites won't ship to US destinations or won't sell

> > it at

> > > > > all.

> > > > > >

> > > > > >As to liver problems, they are rare and I believe much rarer

> > than for

> > > > > example

> > > > > >using statin " cholesterol lowering " drugs. One can always get

> > > your liver

> > > > > >checked. The Life Extension Foundation offers complete

> > > > > CBC/CMP+cholesterol

> > > > > >test for $35.

> > > > > >

> > > > > >--

> > > > > >

> > > > > >Steve -

> > > > >

> > > >

> > >

> >

>

<mailto:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net><mailt\

o:dudescholar2%40basicmail.net>dudescholar2@...

>

> > <mailto:dudescholar2%40basicmail.net>

> > > <mailto:dudescholar2%40basicmail.net>

> > > >

> > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > >

> > > > > > " Convictions are more dangerous enemies of truth than lies. "

> > > > > >--Friedrich Nietzsche

> > > > > >

> > > > > >

> > > > >

> > > > >

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Share on other sites

The ALC/Priacetam combo is a pretty popular one. I try to buy

everything in bulk, it's the only way to go if you're of normal means

and want to pursue a longevity/nootropic regimen.

I drink a fair amount of coffee and tea and have never had a problem, in

fact I'm pretty robust health and energy-wise. I also enjoy both quite

a bit.. It's entirely possible that we have different physiologies

which naturally cause us to react differently.

Also I believe that 100mg of Modafinil is a fairly substantial dose, I

found 50mg had a notable 'vigilance effect' on me.

Brown wrote:

>

> Hi Dave:

>

> Modafinil works well for me. I've tried Piracetam up to 800 mg, but

> not with an equal dose of Acetyl-L-Carnitine. It certainly helps,

> but it wears off much faster than Modafinil and doesn't provide the

> wakefulness. Modafinil also definitely improves both my long-term

> and short-term memory. I drink much less coffee on Modafinil, so

> that is pretty good too. Coffee is small doses is good for you, but

> in larger doses, depletes the minerals in the body and can be bad for

> the kidneys. The only thing I don't like about Modafinil is that it

> wears off so slowly. On the days I decide to use it, when I need to

> work intensely, I take 100 mg (1/2 tablet) when I first get up in the

> morning and when I should be going to bed, 16 to 18 hours later, it

> is still affecting me, making it more difficult to sleep

> initially. But I like the fact that in between, there is no lack of

> strongly-focused attention.

>

> I'm going to try the doses you recommend, the next time I get some

> Piracetam. I take Acetyl-L-Carnitine all the time. Do you buy

> Piracetam in bulk?

>

> Thanks for the information.

>

>

>

> At 08:06 PM 8/18/2006, you wrote:

>

> >I've tried Modafinil and personally feel it's a crappy smart drug,

> >although it's good if you *need* to stay awake longer than caffeine will

> >allow. 1000mg of Acetyl-L-Carnitine with 1000 mg of Piracitam does a

> >lot more for me IMO.

> >

> >Jim wrote:

> > >

> > >

> > > :

> > >

> > > Well, I guess we could all use a piece of that action.

> > >

> > > Did you have any specific problems that you were trying to address?

> > > If so, what relief did you get?

> > >

> > > (I realize that I could be prying into something that you prefer not

> > > discuss here. If so, do not respond)

> > >

> > > Thanks, Jim

> > >

> > > Brown wrote:

> > >

> > > > Hi:

> > > >

> > > > Wakefulness, improved mental focus and cognition.

> > > >

> > > >

> > > >

> > > > At 09:42 AM 8/14/2006, you wrote:

> > > >

> > > > >:

> > > > >

> > > > >I guess I missed the earlier post. What do you take it for and what

> > > > >effects have you

> > > > >observed ?

> > > > >

> > > > >Jim

> > > > >

> > > > > Brown wrote:

> > > > >

> > > > > > Hi:

> > > > > >

> > > > > > I've easily bought Modafinil from international sources. It

> works

> > > > > > well. It is not addictive at all. It is probably not very liver

> > > > > > toxic as I couldn't find much about that beyond warnings. I

> posted a

> > > > > > source in my previous post. I've not tried Adrafinil. I've been

> > > > > > using Modafinil at 100 mg for about 2 weeks with some days off.

> > > > > >

> > > > > >

> > > > > >

> > > > > > At 09:46 PM 8/13/2006, you wrote:

> > > > > >

> > > > > > >On Sunday 13 August 2006 9:37 pm, Apricot85 wrote:

> > > > > > > > Do you (or anyone) use it only for selected occasions?

> Or more

> > > > > > > > regularly? Have you (or anyone) tried both adrafinil and

> > > > > > monofidil? And

> > > > > > > > if so have you perceived any difference between the two? I

> > > > have taken

> > > > > > > > adrafinil & liked the wakefulness ... but I've cut it

> out with

> > > > a fear

> > > > > > > > for liver.

> > > > > > >

> > > > > > >I've tried adrafinil several times and got no response. It is

> > > > > > available from

> > > > > > >international sources. Modafinil requires a prescription in the

> > > > US and is

> > > > > > >scheduled in such a way that it's more difficult to import

> and many

> > > > > > >international sites won't ship to US destinations or won't sell

> > > it at

> > > > > > all.

> > > > > > >

> > > > > > >As to liver problems, they are rare and I believe much rarer

> > > than for

> > > > > > example

> > > > > > >using statin " cholesterol lowering " drugs. One can always get

> > > > your liver

> > > > > > >checked. The Life Extension Foundation offers complete

> > > > > > CBC/CMP+cholesterol

> > > > > > >test for $35.

> > > > > > >

> > > > > > >--

> > > > > > >

> > > > > > >Steve -

> > > > > >

> > > > >

> > > >

> > >

> >

>

<mailto:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net><mailt\

o:dudescholar2%40basicmail.net>dudescholar2@...

> <mailto:dudescholar2%40basicmail.net>

> >

> > > <mailto:dudescholar2%40basicmail.net>

> > > > <mailto:dudescholar2%40basicmail.net>

> > > > >

> > > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > > >

> > > > > > > " Convictions are more dangerous enemies of truth than lies. "

> > > > > > >--Friedrich Nietzsche

> > > > > > >

> > > > > > >

> > > > > >

> > > > > >

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Hi:

Where do you get those in bulk? Modafinil comes in 100mg or 200mg

tablets only. The most common dose is 200mg and above in clinical

use. I find that 200 is pretty intense and 100 is much better. I'm

sure that 50mg (half of the smaller tablet) would offer significant effect.

At 11:05 PM 8/21/2006, you wrote:

>The ALC/Priacetam combo is a pretty popular one. I try to buy

>everything in bulk, it's the only way to go if you're of normal means

>and want to pursue a longevity/nootropic regimen.

>

>I drink a fair amount of coffee and tea and have never had a problem, in

>fact I'm pretty robust health and energy-wise. I also enjoy both quite

>a bit.. It's entirely possible that we have different physiologies

>which naturally cause us to react differently.

>

>Also I believe that 100mg of Modafinil is a fairly substantial dose, I

>found 50mg had a notable 'vigilance effect' on me.

>

> Brown wrote:

> >

> > Hi Dave:

> >

> > Modafinil works well for me. I've tried Piracetam up to 800 mg, but

> > not with an equal dose of Acetyl-L-Carnitine. It certainly helps,

> > but it wears off much faster than Modafinil and doesn't provide the

> > wakefulness. Modafinil also definitely improves both my long-term

> > and short-term memory. I drink much less coffee on Modafinil, so

> > that is pretty good too. Coffee is small doses is good for you, but

> > in larger doses, depletes the minerals in the body and can be bad for

> > the kidneys. The only thing I don't like about Modafinil is that it

> > wears off so slowly. On the days I decide to use it, when I need to

> > work intensely, I take 100 mg (1/2 tablet) when I first get up in the

> > morning and when I should be going to bed, 16 to 18 hours later, it

> > is still affecting me, making it more difficult to sleep

> > initially. But I like the fact that in between, there is no lack of

> > strongly-focused attention.

> >

> > I'm going to try the doses you recommend, the next time I get some

> > Piracetam. I take Acetyl-L-Carnitine all the time. Do you buy

> > Piracetam in bulk?

> >

> > Thanks for the information.

> >

> >

> >

> > At 08:06 PM 8/18/2006, you wrote:

> >

> > >I've tried Modafinil and personally feel it's a crappy smart drug,

> > >although it's good if you *need* to stay awake longer than caffeine will

> > >allow. 1000mg of Acetyl-L-Carnitine with 1000 mg of Piracitam does a

> > >lot more for me IMO.

> > >

> > >Jim wrote:

> > > >

> > > >

> > > > :

> > > >

> > > > Well, I guess we could all use a piece of that action.

> > > >

> > > > Did you have any specific problems that you were trying to address?

> > > > If so, what relief did you get?

> > > >

> > > > (I realize that I could be prying into something that you prefer not

> > > > discuss here. If so, do not respond)

> > > >

> > > > Thanks, Jim

> > > >

> > > > Brown wrote:

> > > >

> > > > > Hi:

> > > > >

> > > > > Wakefulness, improved mental focus and cognition.

> > > > >

> > > > >

> > > > >

> > > > > At 09:42 AM 8/14/2006, you wrote:

> > > > >

> > > > > >:

> > > > > >

> > > > > >I guess I missed the earlier post. What do you take it for and what

> > > > > >effects have you

> > > > > >observed ?

> > > > > >

> > > > > >Jim

> > > > > >

> > > > > > Brown wrote:

> > > > > >

> > > > > > > Hi:

> > > > > > >

> > > > > > > I've easily bought Modafinil from international sources. It

> > works

> > > > > > > well. It is not addictive at all. It is probably not very liver

> > > > > > > toxic as I couldn't find much about that beyond warnings. I

> > posted a

> > > > > > > source in my previous post. I've not tried Adrafinil. I've been

> > > > > > > using Modafinil at 100 mg for about 2 weeks with some days off.

> > > > > > >

> > > > > > >

> > > > > > >

> > > > > > > At 09:46 PM 8/13/2006, you wrote:

> > > > > > >

> > > > > > > >On Sunday 13 August 2006 9:37 pm, Apricot85 wrote:

> > > > > > > > > Do you (or anyone) use it only for selected occasions?

> > Or more

> > > > > > > > > regularly? Have you (or anyone) tried both adrafinil and

> > > > > > > monofidil? And

> > > > > > > > > if so have you perceived any difference between the two? I

> > > > > have taken

> > > > > > > > > adrafinil & liked the wakefulness ... but I've cut it

> > out with

> > > > > a fear

> > > > > > > > > for liver.

> > > > > > > >

> > > > > > > >I've tried adrafinil several times and got no response. It is

> > > > > > > available from

> > > > > > > >international sources. Modafinil requires a prescription in the

> > > > > US and is

> > > > > > > >scheduled in such a way that it's more difficult to import

> > and many

> > > > > > > >international sites won't ship to US destinations or won't sell

> > > > it at

> > > > > > > all.

> > > > > > > >

> > > > > > > >As to liver problems, they are rare and I believe much rarer

> > > > than for

> > > > > > > example

> > > > > > > >using statin " cholesterol lowering " drugs. One can always get

> > > > > your liver

> > > > > > > >checked. The Life Extension Foundation offers complete

> > > > > > > CBC/CMP+cholesterol

> > > > > > > >test for $35.

> > > > > > > >

> > > > > > > >--

> > > > > > > >

> > > > > > > >Steve -

> > > > > > >

> > > > > >

> > > > >

> > > >

> > >

> >

>

<mailto:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net><mailt\

o:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net>dudescholar2\

@basicmail.net

>

> > <mailto:dudescholar2%40basicmail.net>

> > >

> > > > <mailto:dudescholar2%40basicmail.net>

> > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > >

> > > > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > > > >

> > > > > > > > " Convictions are more dangerous enemies of truth than lies. "

> > > > > > > >--Friedrich Nietzsche

> > > > > > > >

> > > > > > > >

> > > > > > >

> > > > > > >

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Share on other sites

I try to buy everything I like and use in bulk.

Brown wrote:

>

> Hi:

>

> Where do you get those in bulk? Modafinil comes in 100mg or 200mg

> tablets only. The most common dose is 200mg and above in clinical

> use. I find that 200 is pretty intense and 100 is much better. I'm

> sure that 50mg (half of the smaller tablet) would offer significant

> effect.

>

>

>

> At 11:05 PM 8/21/2006, you wrote:

>

> >The ALC/Priacetam combo is a pretty popular one. I try to buy

> >everything in bulk, it's the only way to go if you're of normal means

> >and want to pursue a longevity/nootropic regimen.

> >

> >I drink a fair amount of coffee and tea and have never had a problem, in

> >fact I'm pretty robust health and energy-wise. I also enjoy both quite

> >a bit.. It's entirely possible that we have different physiologies

> >which naturally cause us to react differently.

> >

> >Also I believe that 100mg of Modafinil is a fairly substantial dose, I

> >found 50mg had a notable 'vigilance effect' on me.

> >

> > Brown wrote:

> > >

> > > Hi Dave:

> > >

> > > Modafinil works well for me. I've tried Piracetam up to 800 mg, but

> > > not with an equal dose of Acetyl-L-Carnitine. It certainly helps,

> > > but it wears off much faster than Modafinil and doesn't provide the

> > > wakefulness. Modafinil also definitely improves both my long-term

> > > and short-term memory. I drink much less coffee on Modafinil, so

> > > that is pretty good too. Coffee is small doses is good for you, but

> > > in larger doses, depletes the minerals in the body and can be bad for

> > > the kidneys. The only thing I don't like about Modafinil is that it

> > > wears off so slowly. On the days I decide to use it, when I need to

> > > work intensely, I take 100 mg (1/2 tablet) when I first get up in the

> > > morning and when I should be going to bed, 16 to 18 hours later, it

> > > is still affecting me, making it more difficult to sleep

> > > initially. But I like the fact that in between, there is no lack of

> > > strongly-focused attention.

> > >

> > > I'm going to try the doses you recommend, the next time I get some

> > > Piracetam. I take Acetyl-L-Carnitine all the time. Do you buy

> > > Piracetam in bulk?

> > >

> > > Thanks for the information.

> > >

> > >

> > >

> > > At 08:06 PM 8/18/2006, you wrote:

> > >

> > > >I've tried Modafinil and personally feel it's a crappy smart drug,

> > > >although it's good if you *need* to stay awake longer than

> caffeine will

> > > >allow. 1000mg of Acetyl-L-Carnitine with 1000 mg of Piracitam does a

> > > >lot more for me IMO.

> > > >

> > > >Jim wrote:

> > > > >

> > > > >

> > > > > :

> > > > >

> > > > > Well, I guess we could all use a piece of that action.

> > > > >

> > > > > Did you have any specific problems that you were trying to

> address?

> > > > > If so, what relief did you get?

> > > > >

> > > > > (I realize that I could be prying into something that you

> prefer not

> > > > > discuss here. If so, do not respond)

> > > > >

> > > > > Thanks, Jim

> > > > >

> > > > > Brown wrote:

> > > > >

> > > > > > Hi:

> > > > > >

> > > > > > Wakefulness, improved mental focus and cognition.

> > > > > >

> > > > > >

> > > > > >

> > > > > > At 09:42 AM 8/14/2006, you wrote:

> > > > > >

> > > > > > >:

> > > > > > >

> > > > > > >I guess I missed the earlier post. What do you take it for

> and what

> > > > > > >effects have you

> > > > > > >observed ?

> > > > > > >

> > > > > > >Jim

> > > > > > >

> > > > > > > Brown wrote:

> > > > > > >

> > > > > > > > Hi:

> > > > > > > >

> > > > > > > > I've easily bought Modafinil from international sources. It

> > > works

> > > > > > > > well. It is not addictive at all. It is probably not

> very liver

> > > > > > > > toxic as I couldn't find much about that beyond warnings. I

> > > posted a

> > > > > > > > source in my previous post. I've not tried Adrafinil.

> I've been

> > > > > > > > using Modafinil at 100 mg for about 2 weeks with some

> days off.

> > > > > > > >

> > > > > > > >

> > > > > > > >

> > > > > > > > At 09:46 PM 8/13/2006, you wrote:

> > > > > > > >

> > > > > > > > >On Sunday 13 August 2006 9:37 pm, Apricot85 wrote:

> > > > > > > > > > Do you (or anyone) use it only for selected occasions?

> > > Or more

> > > > > > > > > > regularly? Have you (or anyone) tried both adrafinil and

> > > > > > > > monofidil? And

> > > > > > > > > > if so have you perceived any difference between the

> two? I

> > > > > > have taken

> > > > > > > > > > adrafinil & liked the wakefulness ... but I've cut it

> > > out with

> > > > > > a fear

> > > > > > > > > > for liver.

> > > > > > > > >

> > > > > > > > >I've tried adrafinil several times and got no response.

> It is

> > > > > > > > available from

> > > > > > > > >international sources. Modafinil requires a

> prescription in the

> > > > > > US and is

> > > > > > > > >scheduled in such a way that it's more difficult to import

> > > and many

> > > > > > > > >international sites won't ship to US destinations or

> won't sell

> > > > > it at

> > > > > > > > all.

> > > > > > > > >

> > > > > > > > >As to liver problems, they are rare and I believe much

> rarer

> > > > > than for

> > > > > > > > example

> > > > > > > > >using statin " cholesterol lowering " drugs. One can

> always get

> > > > > > your liver

> > > > > > > > >checked. The Life Extension Foundation offers complete

> > > > > > > > CBC/CMP+cholesterol

> > > > > > > > >test for $35.

> > > > > > > > >

> > > > > > > > >--

> > > > > > > > >

> > > > > > > > >Steve -

> > > > > > > >

> > > > > > >

> > > > > >

> > > > >

> > > >

> > >

> >

>

<mailto:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net><mailt\

o:dudescholar2%40basicmail.net><mailto:dudescholar2%40basicmail.net>dudescholar2\

@basicmail.net

> <mailto:dudescholar2%40basicmail.net>

> >

> > > <mailto:dudescholar2%40basicmail.net>

> > > >

> > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > > >

> > > > > > > > <mailto:dudescholar2%40basicmail.net>

> > > > > > > > >

> > > > > > > > > " Convictions are more dangerous enemies of truth than

> lies. "

> > > > > > > > >--Friedrich Nietzsche

> > > > > > > > >

> > > > > > > > >

> > > > > > > >

> > > > > > > >

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