Re: Life is a Devil's Bargain: Cancer or Aging,,Deterioration of ...

[Guest guest]

This also explains why the best anti-aging option to date is calorie

restriction. I have been following the research for decades and my current

regimen

is calorie restriction though every-other-day fasting. There is a

significant stimulation of the SIR2 pathway, and inhibition of the human

equivalent to

GAF2 pathways. The net effect is turning down this " protective " aging

pathway, and simultaneously reducing cancer risk via another pathway. (also

nearly

eliminating the diabetes risk). The advantage of this method of CR is

several fold: 1) you are not always hungry, 2) >24 hours without food

stimulates

an enzyme pathway the helps eliminate waste, 3) it's great mental discipline,

and 4) coupled with exercise on the fasting day, you can preserve muscle

mass,and selectively stimulate the lipolysis pathway. After doing this for 2

years, I'm in the best shape of my life, and still improving. If you are

looking for a magic pill to accomplish all this, I'm afraid you'll have to wait

several decades. Of course, balancing all your hormones, and a comprehensive

anti-oxidant/supplement regimen are also essential. It's not easy, but most

things worth accomplishing seldom are.

R , MD

[Guest guest]

Hi:

I took a look at this supplement. It seems to be an expensive multi

vitamin (and not that multi either) with a few good chelated

minerals, amino acids and herbs. I'm taking all those things and

paying a lot less per the equivalent. They have perhaps discovered

that many mental disorders are created by or exacerbated by

nutritional deficiencies. Their proprietary blend has several

ingredients that have marked mental effects, like glutamine, choline,

inositol, ginko, DL-phenylalanine and methionine from my own

experience. Methionine is a real energy and endurance booster, not

as promoted as it should be. If they've put together a " perfect

blend " for mental health, then I suppose that they have the right to

charge a reasonable price for it. God knows the drug companies abuse

that right every chance they get, charging unreasonable prices.

Below is a list of the ingredients per serving that they sell for $69

per one-month supply: Also they have Vitamin C and Iron in the same

supplement - a toxic mix.

Nevertheless, some of their research looks interesting with

impressive results. Of course orthomolecular treatment, (also from

Canada) before this also did and of note there is only a tiny bit of

niacin (B3) in this pill, compared to ortho's mega dose for mental illness.

http://www.truehope.com/_research/research1.asp

----------

CNS PROPRIETARY BLEND

444.1 mg

dl-phenylalanine, glutamine, citrus bioflavanoids, grape seed,

choline bitartrate, inositol, ginkgo biloba, methionine, germanium

sesquioxide, boron, vanadium, nickel

Nutrient

Amount Per Serving

Vitamin A

1535 IU

Vitamin C

160 mg

Vitamin D

384 IU

Vitamin E

96 IU

Vitamin B1

4.8 mg

Vitamin B2

3.6 mg

Vitamin B3

24 mg

Vitamin B5

5.8 mg

Vitamin B6

9.6 mg

Vitamin B9

384 mcg

Vitamin B12

240 mcg

Vitamin H

288 mcg

Calcium

352 mg

Phosphorous

224 mg

Magnesium

160 mg

Potassium

64 mg

Iodine

54.4 mcg

Zinc

12.8 mg

Selenium

54.4 mcg

Copper

1.9 mg

Manganese

2.6 mg

Chromium

166.4 mcg

Molybdenum

38.4 mcg

Iron

3.7 mg

At 09:01 AM 9/21/2006, you wrote:

>This also explains why the best anti-aging option to date is calorie

>restriction. I have been following the research for decades and my

>current regimen

>is calorie restriction though every-other-day fasting. There is a

>significant stimulation of the SIR2 pathway, and inhibition of the

>human equivalent to

>GAF2 pathways. The net effect is turning down this " protective " aging

>pathway, and simultaneously reducing cancer risk via another

>pathway. (also nearly

>eliminating the diabetes risk). The advantage of this method of CR is

>several fold: 1) you are not always hungry, 2) >24 hours without

>food stimulates

>an enzyme pathway the helps eliminate waste, 3) it's great mental discipline,

>and 4) coupled with exercise on the fasting day, you can preserve muscle

>mass,and selectively stimulate the lipolysis pathway. After doing this for 2

>years, I'm in the best shape of my life, and still improving. If you are

>looking for a magic pill to accomplish all this, I'm afraid you'll

>have to wait

>several decades. Of course, balancing all your hormones, and a comprehensive

>anti-oxidant/supplement regimen are also essential. It's not easy, but most

>things worth accomplishing seldom are.

> R , MD

>

>

>

[Guest guest]

Hi:

These studies were not a surprise to me and also do not represent a

paradox in my view The fact is that cancer and stem cells are part

of the immortal line of cells that include reproductive cells as well

and this fact is key to this issue. Remember, we are all descendents

of single cells passed on from antiquity, by immortal cell lines that

differentiate into mortal cells making up the rest of our

bodies. Cancer is a aberration that has the immortal genes unlocked

within its cells, even though they are normally differentiated,

unlike normal stem cells.

The fact is that the body has several defences against cancer, from

DNA damage protection to the immune response that kills cancerous

cells. Most of us produce cancer cells all the time, but the immune

system recognizes and destroys them. It is likely the buildup of

toxins in our bodies that defeats the immune system's ability to

recognize and defeat cancer.

I believe that the primary benefit of a calorie restricted diet is

defeating glycosylation. Another important component is reduction in

waste build up. My take on the alternate eating and fasting regimen

that you describe is that it probably gives you superior waste

removal plus the benefits of reduced glycosylation. Periodic body

cleansing is a very important component of life extension and I know

that I need to do more of it.

Thanks for reminding us of that.

At 09:01 AM 9/21/2006, you wrote:

>This also explains why the best anti-aging option to date is calorie

>restriction. I have been following the research for decades and my

>current regimen

>is calorie restriction though every-other-day fasting. There is a

>significant stimulation of the SIR2 pathway, and inhibition of the

>human equivalent to

>GAF2 pathways. The net effect is turning down this " protective " aging

>pathway, and simultaneously reducing cancer risk via another

>pathway. (also nearly

>eliminating the diabetes risk). The advantage of this method of CR is

>several fold: 1) you are not always hungry, 2) >24 hours without

>food stimulates

>an enzyme pathway the helps eliminate waste, 3) it's great mental discipline,

>and 4) coupled with exercise on the fasting day, you can preserve muscle

>mass,and selectively stimulate the lipolysis pathway. After doing this for 2

>years, I'm in the best shape of my life, and still improving. If you are

>looking for a magic pill to accomplish all this, I'm afraid you'll

>have to wait

>several decades. Of course, balancing all your hormones, and a comprehensive

>anti-oxidant/supplement regimen are also essential. It's not easy, but most

>things worth accomplishing seldom are.

> R , MD

>

>

>

[Guest guest]

Those of you interested in breaking up AGE's should look into carnosine

supplementation. Carnosine also extends the Hayfleck limit.

Brown wrote:

>

> Hi:

>

> These studies were not a surprise to me and also do not represent a

> paradox in my view The fact is that cancer and stem cells are part

> of the immortal line of cells that include reproductive cells as well

> and this fact is key to this issue. Remember, we are all descendents

> of single cells passed on from antiquity, by immortal cell lines that

> differentiate into mortal cells making up the rest of our

> bodies. Cancer is a aberration that has the immortal genes unlocked

> within its cells, even though they are normally differentiated,

> unlike normal stem cells.

>

> The fact is that the body has several defences against cancer, from

> DNA damage protection to the immune response that kills cancerous

> cells. Most of us produce cancer cells all the time, but the immune

> system recognizes and destroys them. It is likely the buildup of

> toxins in our bodies that defeats the immune system's ability to

> recognize and defeat cancer.

>

> I believe that the primary benefit of a calorie restricted diet is

> defeating glycosylation. Another important component is reduction in

> waste build up. My take on the alternate eating and fasting regimen

> that you describe is that it probably gives you superior waste

> removal plus the benefits of reduced glycosylation. Periodic body

> cleansing is a very important component of life extension and I know

> that I need to do more of it.

>

> Thanks for reminding us of that.

>

>

>

> At 09:01 AM 9/21/2006, you wrote:

>

> >This also explains why the best anti-aging option to date is calorie

> >restriction. I have been following the research for decades and my

> >current regimen

> >is calorie restriction though every-other-day fasting. There is a

> >significant stimulation of the SIR2 pathway, and inhibition of the

> >human equivalent to

> >GAF2 pathways. The net effect is turning down this " protective " aging

> >pathway, and simultaneously reducing cancer risk via another

> >pathway. (also nearly

> >eliminating the diabetes risk). The advantage of this method of CR is

> >several fold: 1) you are not always hungry, 2) >24 hours without

> >food stimulates

> >an enzyme pathway the helps eliminate waste, 3) it's great mental

> discipline,

> >and 4) coupled with exercise on the fasting day, you can preserve muscle

> >mass,and selectively stimulate the lipolysis pathway. After doing

> this for 2

> >years, I'm in the best shape of my life, and still improving. If you are

> >looking for a magic pill to accomplish all this, I'm afraid you'll

> >have to wait

> >several decades. Of course, balancing all your hormones, and a

> comprehensive

> >anti-oxidant/supplement regimen are also essential. It's not easy,

> but most

> >things worth accomplishing seldom are.

> > R , MD

> >

> >

> >

[Guest guest]

Dave:

Agreed. In fact carnosine is a good preventer of the cross linking

effects of both glycosylation and acetaldehyde (breakdown of alcohol

and present in cigarette smoke - it is the acetaldehyde " high " that

makes people want to smoke and drink simultaneously).

At 12:11 PM 9/21/2006, you wrote:

>Those of you interested in breaking up AGE's should look into carnosine

>supplementation. Carnosine also extends the Hayfleck limit.

>

> Brown wrote:

> >

> > Hi:

> >

> > These studies were not a surprise to me and also do not represent a

> > paradox in my view The fact is that cancer and stem cells are part

> > of the immortal line of cells that include reproductive cells as well

> > and this fact is key to this issue. Remember, we are all descendents

> > of single cells passed on from antiquity, by immortal cell lines that

> > differentiate into mortal cells making up the rest of our

> > bodies. Cancer is a aberration that has the immortal genes unlocked

> > within its cells, even though they are normally differentiated,

> > unlike normal stem cells.

> >

> > The fact is that the body has several defences against cancer, from

> > DNA damage protection to the immune response that kills cancerous

> > cells. Most of us produce cancer cells all the time, but the immune

> > system recognizes and destroys them. It is likely the buildup of

> > toxins in our bodies that defeats the immune system's ability to

> > recognize and defeat cancer.

> >

> > I believe that the primary benefit of a calorie restricted diet is

> > defeating glycosylation. Another important component is reduction in

> > waste build up. My take on the alternate eating and fasting regimen

> > that you describe is that it probably gives you superior waste

> > removal plus the benefits of reduced glycosylation. Periodic body

> > cleansing is a very important component of life extension and I know

> > that I need to do more of it.

> >

> > Thanks for reminding us of that.

> >

> >

> >

> > At 09:01 AM 9/21/2006, you wrote:

> >

> > >This also explains why the best anti-aging option to date is calorie

> > >restriction. I have been following the research for decades and my

> > >current regimen

> > >is calorie restriction though every-other-day fasting. There is a

> > >significant stimulation of the SIR2 pathway, and inhibition of the

> > >human equivalent to

> > >GAF2 pathways. The net effect is turning down this " protective " aging

> > >pathway, and simultaneously reducing cancer risk via another

> > >pathway. (also nearly

> > >eliminating the diabetes risk). The advantage of this method of CR is

> > >several fold: 1) you are not always hungry, 2) >24 hours without

> > >food stimulates

> > >an enzyme pathway the helps eliminate waste, 3) it's great mental

> > discipline,

> > >and 4) coupled with exercise on the fasting day, you can preserve muscle

> > >mass,and selectively stimulate the lipolysis pathway. After doing

> > this for 2

> > >years, I'm in the best shape of my life, and still improving. If you are

> > >looking for a magic pill to accomplish all this, I'm afraid you'll

> > >have to wait

> > >several decades. Of course, balancing all your hormones, and a

> > comprehensive

> > >anti-oxidant/supplement regimen are also essential. It's not easy,

> > but most

> > >things worth accomplishing seldom are.

> > > R , MD

> > >

> > >

> > >

[Guest guest]

Mmm... Acetaldehyde...

Seriously though, I've read that Carnosine can *break up* AGEs.

Brown wrote:

>

> Dave:

>

> Agreed. In fact carnosine is a good preventer of the cross linking

> effects of both glycosylation and acetaldehyde (breakdown of alcohol

> and present in cigarette smoke - it is the acetaldehyde " high " that

> makes people want to smoke and drink simultaneously).

>

>

>

> At 12:11 PM 9/21/2006, you wrote:

>

> >Those of you interested in breaking up AGE's should look into carnosine

> >supplementation. Carnosine also extends the Hayfleck limit.

> >

> > Brown wrote:

> > >

> > > Hi:

> > >

> > > These studies were not a surprise to me and also do not represent a

> > > paradox in my view The fact is that cancer and stem cells are part

> > > of the immortal line of cells that include reproductive cells as well

> > > and this fact is key to this issue. Remember, we are all descendents

> > > of single cells passed on from antiquity, by immortal cell lines that

> > > differentiate into mortal cells making up the rest of our

> > > bodies. Cancer is a aberration that has the immortal genes unlocked

> > > within its cells, even though they are normally differentiated,

> > > unlike normal stem cells.

> > >

> > > The fact is that the body has several defences against cancer, from

> > > DNA damage protection to the immune response that kills cancerous

> > > cells. Most of us produce cancer cells all the time, but the immune

> > > system recognizes and destroys them. It is likely the buildup of

> > > toxins in our bodies that defeats the immune system's ability to

> > > recognize and defeat cancer.

> > >

> > > I believe that the primary benefit of a calorie restricted diet is

> > > defeating glycosylation. Another important component is reduction in

> > > waste build up. My take on the alternate eating and fasting regimen

> > > that you describe is that it probably gives you superior waste

> > > removal plus the benefits of reduced glycosylation. Periodic body

> > > cleansing is a very important component of life extension and I know

> > > that I need to do more of it.

> > >

> > > Thanks for reminding us of that.

> > >

> > >

> > >

> > > At 09:01 AM 9/21/2006, you wrote:

> > >

> > > >This also explains why the best anti-aging option to date is calorie

> > > >restriction. I have been following the research for decades and my

> > > >current regimen

> > > >is calorie restriction though every-other-day fasting. There is a

> > > >significant stimulation of the SIR2 pathway, and inhibition of the

> > > >human equivalent to

> > > >GAF2 pathways. The net effect is turning down this " protective " aging

> > > >pathway, and simultaneously reducing cancer risk via another

> > > >pathway. (also nearly

> > > >eliminating the diabetes risk). The advantage of this method of CR is

> > > >several fold: 1) you are not always hungry, 2) >24 hours without

> > > >food stimulates

> > > >an enzyme pathway the helps eliminate waste, 3) it's great mental

> > > discipline,

> > > >and 4) coupled with exercise on the fasting day, you can preserve

> muscle

> > > >mass,and selectively stimulate the lipolysis pathway. After doing

> > > this for 2

> > > >years, I'm in the best shape of my life, and still improving. If

> you are

> > > >looking for a magic pill to accomplish all this, I'm afraid you'll

> > > >have to wait

> > > >several decades. Of course, balancing all your hormones, and a

> > > comprehensive

> > > >anti-oxidant/supplement regimen are also essential. It's not easy,

> > > but most

> > > >things worth accomplishing seldom are.

> > > > R , MD

> > > >

> > > >

> > > >

[Guest guest]

Hey Dave:

Yes the acetaldehyde is a high in which your brain cells are

dying....oooooohhh. Very addictive. Yeah, give me more! >:-}

Carnosine does break up AGEs, lots of research. The chemical that

Dr. takes, ALT-711 (Phenacyldimethylthiazolium chloride or

4,5-dimethyl-3(2-oxo-phenylethyl)-thiazolium chloride) has shown to

be safe and to break up the cross-linking caused by AGEs,

glycosylation and acetaldehyde. People's blood vessels become

flexible again after hardening and good things happen. Dr.

takes carnosine too, as well as NAC.

At the lecture I went to tonight in Palo Alto, first Dr. Cathcart,

the Dr. famous for using high Vitamin C doses spoke. He has cured

AIDS, cancer and practically every viral disease known to man with

intravenous Vitamin C in the 100+ gram dose range. They're making a

movie showing dramatic cures as with shingles, the patient is often

cured in one IV session lasting 4 hours, ingesting 100 grams or so of

Vitamin C.

The star of the show was Berkeley professor and researcher Dr. Bruce

Ames, author of over 500 scientific papers, the subject was

Mitochondria and Aging. Their research has shown that a combination

of Acetyl-L-Carnitine and Alpha Lipoic Acid along with biotin, zinc

and in the presence of sufficient quantities of b complex and trace

minerals, brings old mitochondria into near operational

specifications of young mitochondria. Thes nutrients prevent AGEs

like carnosine in the mitochondria, the powerhouses of our cells,

each cell containing about 500 each of them. They've done research

showing increases in energy, intelligence and general performance

along with lowering of blood pressure and other beneficial

effects. The UC Reagents have patented the combination of ALC plus

ALA, and the company that licensed it is selling $5M per year of the

supplement. It is quite interesting how they work in tandem.

At 12:02 AM 9/22/2006, you wrote:

>Mmm... Acetaldehyde...

>

>Seriously though, I've read that Carnosine can *break up* AGEs.

>

> Brown wrote:

> >

> > Dave:

> >

> > Agreed. In fact carnosine is a good preventer of the cross linking

> > effects of both glycosylation and acetaldehyde (breakdown of alcohol

> > and present in cigarette smoke - it is the acetaldehyde " high " that

> > makes people want to smoke and drink simultaneously).

> >

> >

> >

> > At 12:11 PM 9/21/2006, you wrote:

> >

> > >Those of you interested in breaking up AGE's should look into carnosine

> > >supplementation. Carnosine also extends the Hayfleck limit.

> > >

> > > Brown wrote:

> > > >

> > > > Hi:

> > > >

> > > > These studies were not a surprise to me and also do not represent a

> > > > paradox in my view The fact is that cancer and stem cells are part

> > > > of the immortal line of cells that include reproductive cells as well

> > > > and this fact is key to this issue. Remember, we are all descendents

> > > > of single cells passed on from antiquity, by immortal cell lines that

> > > > differentiate into mortal cells making up the rest of our

> > > > bodies. Cancer is a aberration that has the immortal genes unlocked

> > > > within its cells, even though they are normally differentiated,

> > > > unlike normal stem cells.

> > > >

> > > > The fact is that the body has several defences against cancer, from

> > > > DNA damage protection to the immune response that kills cancerous

> > > > cells. Most of us produce cancer cells all the time, but the immune

> > > > system recognizes and destroys them. It is likely the buildup of

> > > > toxins in our bodies that defeats the immune system's ability to

> > > > recognize and defeat cancer.

> > > >

> > > > I believe that the primary benefit of a calorie restricted diet is

> > > > defeating glycosylation. Another important component is reduction in

> > > > waste build up. My take on the alternate eating and fasting regimen

> > > > that you describe is that it probably gives you superior waste

> > > > removal plus the benefits of reduced glycosylation. Periodic body

> > > > cleansing is a very important component of life extension and I know

> > > > that I need to do more of it.

> > > >

> > > > Thanks for reminding us of that.

> > > >

> > > >

> > > >

> > > > At 09:01 AM 9/21/2006, you wrote:

> > > >

> > > > >This also explains why the best anti-aging option to date is calorie

> > > > >restriction. I have been following the research for decades and my

> > > > >current regimen

> > > > >is calorie restriction though every-other-day fasting. There is a

> > > > >significant stimulation of the SIR2 pathway, and inhibition of the

> > > > >human equivalent to

> > > > >GAF2 pathways. The net effect is turning down this " protective " aging

> > > > >pathway, and simultaneously reducing cancer risk via another

> > > > >pathway. (also nearly

> > > > >eliminating the diabetes risk). The advantage of this method of CR is

> > > > >several fold: 1) you are not always hungry, 2) >24 hours without

> > > > >food stimulates

> > > > >an enzyme pathway the helps eliminate waste, 3) it's great mental

> > > > discipline,

> > > > >and 4) coupled with exercise on the fasting day, you can preserve

> > muscle

> > > > >mass,and selectively stimulate the lipolysis pathway. After doing

> > > > this for 2

> > > > >years, I'm in the best shape of my life, and still improving. If

> > you are

> > > > >looking for a magic pill to accomplish all this, I'm afraid you'll

> > > > >have to wait

> > > > >several decades. Of course, balancing all your hormones, and a

> > > > comprehensive

> > > > >anti-oxidant/supplement regimen are also essential. It's not easy,

> > > > but most

> > > > >things worth accomplishing seldom are.

> > > > > R , MD

> > > > >

> > > > >

> > > > >

[Guest guest]

Has acetaldehyde, a by product to do with candida, anything to to

with the advice given to candida patients to not have vinegar, do you

suppose?

I'm not clear where the danger lies, as acidity discouarges candida

growth.

Duncan

> > > > >

> > > > > >This also explains why the best anti-aging option to date

is calorie

> > > > > >restriction. I have been following the research for

decades and my

> > > > > >current regimen

> > > > > >is calorie restriction though every-other-day fasting.

There is a

> > > > > >significant stimulation of the SIR2 pathway, and

inhibition of the

> > > > > >human equivalent to

> > > > > >GAF2 pathways. The net effect is turning down

this " protective " aging

> > > > > >pathway, and simultaneously reducing cancer risk via

another

> > > > > >pathway. (also nearly

> > > > > >eliminating the diabetes risk). The advantage of this

method of CR is

> > > > > >several fold: 1) you are not always hungry, 2) >24 hours

without

> > > > > >food stimulates

> > > > > >an enzyme pathway the helps eliminate waste, 3) it's great

mental

> > > > > discipline,

> > > > > >and 4) coupled with exercise on the fasting day, you can

preserve

> > > muscle

> > > > > >mass,and selectively stimulate the lipolysis pathway.

After doing

> > > > > this for 2

> > > > > >years, I'm in the best shape of my life, and still

improving. If

> > > you are

> > > > > >looking for a magic pill to accomplish all this, I'm

afraid you'll

> > > > > >have to wait

> > > > > >several decades. Of course, balancing all your hormones,

and a

> > > > > comprehensive

> > > > > >anti-oxidant/supplement regimen are also essential. It's

not easy,

> > > > > but most

> > > > > >things worth accomplishing seldom are.

> > > > > > R , MD

> > > > > >

> > > > > >

> > > > > >

[Guest guest]

Hi:

I don't agree with that advice with regard to vinegar, but I believe

you're right. Acetaldehyde comes from the breakdown of ethanol, and

yeast can either produce ethanol or directly produce acetaldehyde

depending on the chemical environment, acetaldehyde also comes from

cigarette smoke and auto exhaust. It is one of the most potent

neurotoxins and general toxins we're exposed to. Healthy people

break it down quickly in smaller doses.

When it breaks down, the result is acetate which forms acetic acid or

vinegar. Thus, since vinegar is therefore a byproduct of yeast it is

likely thought that it promotes yeast. Most vinegar, like most

ethanol, kills yeast, which produces both, ironically. There may be

some vinegars that have a carbohydrate or sugar component with them

and of course those vinegars would be ill advised, but any pure

vinegar should help to eliminate, not promote candida. Since vinegar

is often produced by candida, some vinegars actually have some

candida spores in them, and this is the main basis for telling people

to avoid it. I disagree with this because you body will continue to

be full of candida even after you eliminate the problem. You do want

to remove fuel for candida, but not every single source of it. Beer

would still be ill advised, because it has fuel for added

fermentation by candida in its carbohydrates.

Candida infection only comes with a compromised immune system and /

or poor intestinal flora. Cleansing the gut and reinforcing its

flora and getting rid of heavy metals and other toxins is the

answer. Mega doses of vitamin C are one of the best ways to balance

the fight and at the same time stimulate the immune system in the

gut. It supplies the +ions necessary to neutralize the -OH ions from

infections and radicals formed by toxins like acetaldehyde. I've

heard Dr. Cathcart speak several times about curing many, many

patients of candida infections with vitamin C in " bowell titration "

doses (that amount the just starts to cause diarrhea). This is

typically 15 to 50 grams per day taken at 4-5 equal intervals. This

is combined with a probiotic and I'm sure that Inulin, a prebiotic

would also help. Chelation therapy is helpful if the person's immune

system is compromised from heavy metals. I would add Acetyl L

Carnitine and R-Alpha Lipoic Acid as well to further stimulate the

T-cells' energy, working with the vitamin C, as vitamin C is a strong

mediator of cellular (Killer T-Cell) immunity vs. humoral

(B-Cell/antibody) immunity.

At 02:44 PM 9/22/2006, you wrote:

>Has acetaldehyde, a by product to do with candida, anything to to

>with the advice given to candida patients to not have vinegar, do you

>suppose?

>

>I'm not clear where the danger lies, as acidity discouarges candida

>growth.

>

>Duncan

>

>

> > > > > >

> > > > > > >This also explains why the best anti-aging option to date

>is calorie

> > > > > > >restriction. I have been following the research for

>decades and my

> > > > > > >current regimen

> > > > > > >is calorie restriction though every-other-day fasting.

>There is a

> > > > > > >significant stimulation of the SIR2 pathway, and

>inhibition of the

> > > > > > >human equivalent to

> > > > > > >GAF2 pathways. The net effect is turning down

>this " protective " aging

> > > > > > >pathway, and simultaneously reducing cancer risk via

>another

> > > > > > >pathway. (also nearly

> > > > > > >eliminating the diabetes risk). The advantage of this

>method of CR is

> > > > > > >several fold: 1) you are not always hungry, 2) >24 hours

>without

> > > > > > >food stimulates

> > > > > > >an enzyme pathway the helps eliminate waste, 3) it's great

>mental

> > > > > > discipline,

> > > > > > >and 4) coupled with exercise on the fasting day, you can

>preserve

> > > > muscle

> > > > > > >mass,and selectively stimulate the lipolysis pathway.

>After doing

> > > > > > this for 2

> > > > > > >years, I'm in the best shape of my life, and still

>improving. If

> > > > you are

> > > > > > >looking for a magic pill to accomplish all this, I'm

>afraid you'll

> > > > > > >have to wait

> > > > > > >several decades. Of course, balancing all your hormones,

>and a

> > > > > > comprehensive

> > > > > > >anti-oxidant/supplement regimen are also essential. It's

>not easy,

> > > > > > but most

> > > > > > >things worth accomplishing seldom are.

> > > > > > > R , MD

> > > > > > >

> > > > > > >

> > > > > > >

[Guest guest]

,

Great email - I have some comments interspersed:

Brown wrote:

>

> Hey Dave:

>

> Yes the acetaldehyde is a high in which your brain cells are

> dying....oooooohhh. Very addictive. Yeah, give me more! >:-}

>

> Carnosine does break up AGEs, lots of research. The chemical that

> Dr. takes, ALT-711 (Phenacyldimethylthiazolium chloride or

> 4,5-dimethyl-3(2-oxo-phenylethyl)-thiazolium chloride) has shown to

> be safe and to break up the cross-linking caused by AGEs,

> glycosylation and acetaldehyde. People's blood vessels become

> flexible again after hardening and good things happen. Dr.

> takes carnosine too, as well as NAC.

>

NAC = N-Acetly-L-Carnitine?

Also, do you happen to know Dr. Hugh's protocol? I've been using

carnosine successfully to prevent lactic acidosis, but I'd like to know

more about different dosing protocols.

>

> At the lecture I went to tonight in Palo Alto, first Dr. Cathcart,

> the Dr. famous for using high Vitamin C doses spoke. He has cured

> AIDS, cancer and practically every viral disease known to man with

> intravenous Vitamin C in the 100+ gram dose range. They're making a

> movie showing dramatic cures as with shingles, the patient is often

> cured in one IV session lasting 4 hours, ingesting 100 grams or so of

> Vitamin C.

>

For another interesting AIDS cure, check out Malariotherapy (discovered

and promoted by Dr. Hemlich, of the Heimlich maneuver).

>

> The star of the show was Berkeley professor and researcher Dr. Bruce

> Ames, author of over 500 scientific papers, the subject was

> Mitochondria and Aging. Their research has shown that a combination

> of Acetyl-L-Carnitine and Alpha Lipoic Acid along with biotin, zinc

> and in the presence of sufficient quantities of b complex and trace

> minerals, brings old mitochondria into near operational

> specifications of young mitochondria.

>

THAT is some AWESOME INFORMATION. I'm all over keepin' my mitochondria

in fighting trim!

> Thes nutrients prevent AGEs

> like carnosine in the mitochondria, the powerhouses of our cells,

> each cell containing about 500 each of them. They've done research

> showing increases in energy, intelligence and general performance

> along with lowering of blood pressure and other beneficial

> effects. The UC Reagents have patented the combination of ALC plus

> ALA, and the company that licensed it is selling $5M per year of the

> supplement. It is quite interesting how they work in tandem.

>

Patented it, huh? Well, I guess I can't begrudge them making a buck off

it... And some people are liable to take it only if they have to pay an

arm and a leg! Haaa!

[Guest guest]

Hi Dave:

My answers interspersed.

At 04:01 PM 9/24/2006, you wrote:

>,

>

>Great email - I have some comments interspersed:

>

> Brown wrote:

> >

> > Hey Dave:

> >

> > Yes the acetaldehyde is a high in which your brain cells are

> > dying....oooooohhh. Very addictive. Yeah, give me more! >:-}

> >

> > Carnosine does break up AGEs, lots of research. The chemical that

> > Dr. takes, ALT-711 (Phenacyldimethylthiazolium chloride or

> > 4,5-dimethyl-3(2-oxo-phenylethyl)-thiazolium chloride) has shown to

> > be safe and to break up the cross-linking caused by AGEs,

> > glycosylation and acetaldehyde. People's blood vessels become

> > flexible again after hardening and good things happen. Dr.

> > takes carnosine too, as well as NAC.

> >

>

>NAC = N-Acetly-L-Carnitine?

N-Acetyl-L-Cysteine

N-Acetyl-L-Carnosine is generally used in eye drops to prevent

degenerative diseases of the eye, but can be taken internally if you

can find it. It isn't really available as a powder or tablet except

from chemical houses or bulk wholesalers, I believe. If you find it,

other than in eye drops, let me know.

>Also, do you happen to know Dr. Hugh's protocol? I've been using

>carnosine successfully to prevent lactic acidosis, but I'd like to know

>more about different dosing protocols.

Look at his last post, he briefly describes it. I just found him on

an alternative Physician site, he is in South Carolina. I plan to

write him when I get the time because I want to know more about his

use of ALT-711 (see his post and my response).

> >

> > At the lecture I went to tonight in Palo Alto, first Dr. Cathcart,

> > the Dr. famous for using high Vitamin C doses spoke. He has cured

> > AIDS, cancer and practically every viral disease known to man with

> > intravenous Vitamin C in the 100+ gram dose range. They're making a

> > movie showing dramatic cures as with shingles, the patient is often

> > cured in one IV session lasting 4 hours, ingesting 100 grams or so of

> > Vitamin C.

> >

>

>For another interesting AIDS cure, check out Malariotherapy (discovered

>and promoted by Dr. Hemlich, of the Heimlich maneuver).

Thanks, I will check it out...

> >

> > The star of the show was Berkeley professor and researcher Dr. Bruce

> > Ames, author of over 500 scientific papers, the subject was

> > Mitochondria and Aging. Their research has shown that a combination

> > of Acetyl-L-Carnitine and Alpha Lipoic Acid along with biotin, zinc

> > and in the presence of sufficient quantities of b complex and trace

> > minerals, brings old mitochondria into near operational

> > specifications of young mitochondria.

> >

>

>THAT is some AWESOME INFORMATION. I'm all over keepin' my mitochondria

>in fighting trim!

From the lecture with Dr. Ames. Great research. The LEF

Mitochondria formula is really pretty good for that .

> > Thes nutrients prevent AGEs

> > like carnosine in the mitochondria, the powerhouses of our cells,

> > each cell containing about 500 each of them. They've done research

> > showing increases in energy, intelligence and general performance

> > along with lowering of blood pressure and other beneficial

> > effects. The UC Reagents have patented the combination of ALC plus

> > ALA, and the company that licensed it is selling $5M per year of the

> > supplement. It is quite interesting how they work in tandem.

> >

>

>Patented it, huh? Well, I guess I can't begrudge them making a buck off

>it... And some people are liable to take it only if they have to pay an

>arm and a leg! Haaa!

Well, lots of formulas have the two in them, with a bunch of other

stuff. I doubt that UCB is heavy handed about defending such

patents. Also, I doubt that they'd succeed in a " prior art " battle,

as the two no doubt were in formulas prior to their patent.

>

[Guest guest]

Just for clarity, when I use the abbreviation NAC, it is for N-Acetyl Cystiene

(I take 1gm/day), I do also take Carnitine, and my dose is 1500mg/day When I

get some time I'll write down my entire regimen, with the logic used in

establishing it. (it is highly complex and evolving)

Dr H

Re: Life is a Devil's Bargain: Cancer or

Aging,,Deterioration of ...

,

Great email - I have some comments interspersed:

Brown wrote:

>

> Hey Dave:

>

> Yes the acetaldehyde is a high in which your brain cells are

> dying....oooooohhh. Very addictive. Yeah, give me more! >:-}

>

> Carnosine does break up AGEs, lots of research. The chemical that

> Dr. takes, ALT-711 (Phenacyldimethylthiazolium chloride or

> 4,5-dimethyl-3(2-oxo-phenylethyl)-thiazolium chloride) has shown to

> be safe and to break up the cross-linking caused by AGEs,

> glycosylation and acetaldehyde. People's blood vessels become

> flexible again after hardening and good things happen. Dr.

> takes carnosine too, as well as NAC.

>

NAC = N-Acetly-L-Carnitine?

Also, do you happen to know Dr. Hugh's protocol? I've been using

carnosine successfully to prevent lactic acidosis, but I'd like to know

more about different dosing protocols.

>

> At the lecture I went to tonight in Palo Alto, first Dr. Cathcart,

> the Dr. famous for using high Vitamin C doses spoke. He has cured

> AIDS, cancer and practically every viral disease known to man with

> intravenous Vitamin C in the 100+ gram dose range. They're making a

> movie showing dramatic cures as with shingles, the patient is often

> cured in one IV session lasting 4 hours, ingesting 100 grams or so of

> Vitamin C.

>

For another interesting AIDS cure, check out Malariotherapy (discovered

and promoted by Dr. Hemlich, of the Heimlich maneuver).

>

> The star of the show was Berkeley professor and researcher Dr. Bruce

> Ames, author of over 500 scientific papers, the subject was

> Mitochondria and Aging. Their research has shown that a combination

> of Acetyl-L-Carnitine and Alpha Lipoic Acid along with biotin, zinc

> and in the presence of sufficient quantities of b complex and trace

> minerals, brings old mitochondria into near operational

> specifications of young mitochondria.

>

THAT is some AWESOME INFORMATION. I'm all over keepin' my mitochondria

in fighting trim!

> Thes nutrients prevent AGEs

> like carnosine in the mitochondria, the powerhouses of our cells,

> each cell containing about 500 each of them. They've done research

> showing increases in energy, intelligence and general performance

> along with lowering of blood pressure and other beneficial

> effects. The UC Reagents have patented the combination of ALC plus

> ALA, and the company that licensed it is selling $5M per year of the

> supplement. It is quite interesting how they work in tandem.

>

Patented it, huh? Well, I guess I can't begrudge them making a buck off

it... And some people are liable to take it only if they have to pay an

arm and a leg! Haaa!

[Guest guest]

Hi Dr. H!

I weigh 190 lbs and find that 3.5 grams of carnosine gives me what seems

to be 95% effective immunity from soreness due to lactic acidosis for

about 2 hours. It takes about 20 minutes to kick in. I can tell when

the dose will be effective because I experience a mild " carnosine

flush " , a prickling sensation similar to a niacin flush (just much

reduced in intensity, with no capillary dilation effect). 3 grams gives

some protection, and 2.5 grams isn't enough. I don't even notice 2 grams.

I have noticed a similar flush with ALC (acetyl-l-carnitine) with around

2 grams, but ALC doesn't prevent lactic acidosis (but does appear to

increase my physical energy level). However, using ALC for other

purposes than exercising at those levels is usually overstimulating for me.

Best,

Dave

JRHMD53@... wrote:

>

> Just for clarity, when I use the abbreviation NAC, it is for N-Acetyl

> Cystiene (I take 1gm/day), I do also take Carnitine, and my dose is

> 1500mg/day When I get some time I'll write down my entire regimen,

> with the logic used in establishing it. (it is highly complex and

> evolving)

>

> Dr H

>

>

> Re: Life is a Devil's Bargain: Cancer or

> Aging,,Deterioration of ...

>

> ,

>

> Great email - I have some comments interspersed:

>

> Brown wrote:

> >

> > Hey Dave:

> >

> > Yes the acetaldehyde is a high in which your brain cells are

> > dying....oooooohhh. Very addictive. Yeah, give me more! >:-}

> >

> > Carnosine does break up AGEs, lots of research. The chemical that

> > Dr. takes, ALT-711 (Phenacyldimethylthiazolium chloride or

> > 4,5-dimethyl-3(2-oxo-phenylethyl)-thiazolium chloride) has shown to

> > be safe and to break up the cross-linking caused by AGEs,

> > glycosylation and acetaldehyde. People's blood vessels become

> > flexible again after hardening and good things happen. Dr.

> > takes carnosine too, as well as NAC.

> >

>

> NAC = N-Acetly-L-Carnitine?

>

> Also, do you happen to know Dr. Hugh's protocol? I've been using

> carnosine successfully to prevent lactic acidosis, but I'd like to know

> more about different dosing protocols.

>

> >

> > At the lecture I went to tonight in Palo Alto, first Dr. Cathcart,

> > the Dr. famous for using high Vitamin C doses spoke. He has cured

> > AIDS, cancer and practically every viral disease known to man with

> > intravenous Vitamin C in the 100+ gram dose range. They're making a

> > movie showing dramatic cures as with shingles, the patient is often

> > cured in one IV session lasting 4 hours, ingesting 100 grams or so of

> > Vitamin C.

> >

>

> For another interesting AIDS cure, check out Malariotherapy (discovered

> and promoted by Dr. Hemlich, of the Heimlich maneuver).

>

> >

> > The star of the show was Berkeley professor and researcher Dr. Bruce

> > Ames, author of over 500 scientific papers, the subject was

> > Mitochondria and Aging. Their research has shown that a combination

> > of Acetyl-L-Carnitine and Alpha Lipoic Acid along with biotin, zinc

> > and in the presence of sufficient quantities of b complex and trace

> > minerals, brings old mitochondria into near operational

> > specifications of young mitochondria.

> >

>

> THAT is some AWESOME INFORMATION. I'm all over keepin' my mitochondria

> in fighting trim!

>

> > Thes nutrients prevent AGEs

> > like carnosine in the mitochondria, the powerhouses of our cells,

> > each cell containing about 500 each of them. They've done research

> > showing increases in energy, intelligence and general performance

> > along with lowering of blood pressure and other beneficial

> > effects. The UC Reagents have patented the combination of ALC plus

> > ALA, and the company that licensed it is selling $5M per year of the

> > supplement. It is quite interesting how they work in tandem.

> >

>

> Patented it, huh? Well, I guess I can't begrudge them making a buck off

> it... And some people are liable to take it only if they have to pay an

> arm and a leg! Haaa!

>

>