Guest guest Posted March 31, 2008 Report Share Posted March 31, 2008 I need to redo my message about Guyton and Hall written by dog Drs. ;-) Actually Dr. Guyon (one of my heros) was trained as an MD and surgeon (Harvard I think) and was stricken with polio just at the end of his training. He elected to move to physiology and became one of the most gifted investigators of the regulation of the circulation and trying to simulate it on a computer. At last count his flow chart had over 200 differential equations in it. HIs model is called the Guyton model and when we discuss models of the circulation we refer to his as the Guytonian way of thinking about the circulation. Dr. Hall is one of the best research physiologists in the world and took over the book after Dr. Guyton died. Both have won the big HTN prize called the Ciba award-like the Nobel Prize in HTN. Now called the Novartis Award. I think Dr. Guyton also holds the record for having the most children graduating from Harvard. He had 12 as I recall and maybe 10 graduated from Harvard but dont quote me on that. CE Grim MD Begin forwarded message: > From: Clarence Grim <lowerbp2@...> > Date: March 31, 2008 2:31:34 PM CDT > hyperaldosteronism > Subject: Re: Guyton & Hall > Reply-hyperaldosteronism > > > On Mar 31, 2008, at 2:19 PM, Valarie wrote: > > > I have the 2006 copyright - 11th edition. > > > > Conn's (adenoma) is mentioned in relation to > > 1. Tubular reabsorption (p 342) > > 2. Chronic oversecretion of aldosterone and retention of sodium (p > > 379) > > 3. Regulation of renal tubular hydrogen ion secretion (p 395) > > 4. Metabolic alkalosis (p 398) > > 5. Hypokalemia (p 366) > > > > In Chapter 77, Adrenocortical Hormones, there are two paragraphs > about > > Conn's (p 959). It talks about the important effects - hypokalemia, > > slight > > increase in extracellular fluid volume and blood volume, very slight > > increase in plasma sodium concentration (usually not more than a 4 > to > > 6 > > mEq/L increase), and almost always, hypertension. Talks about > periods > > of > > muscle paralysis caused by hypokalemia. Talks about low renin as a > > diagnostic sign. > > > > None of the reference lists in any of those chapters has a reference > > to > > Conn. > > > > It says, " Treatment of primary aldosteronism is usually surgical > > removal of > > the tumor or of most of the adrenal tissue when hyperplasia is the > > cause. " > > Is that done? > > Recall that this is written by dog doctors-well now today rat doctors. > We rarely take out both adrenals now- before good meds have done this. > > > > > In the Cushing's section, there is a picture of a woman with > Cushing's > > before and after subtotal adrenalectomy. I look Cushinoid, > especially > > after > > two or three hours if early morning sweats. > > Classic Cushing's looks don't change. > > > > And they call economics the " dismal science. " > > > > Val > > > > From: hyperaldosteronism > > [mailto:hyperaldosteronism ] On Behalf Of Clarence > Grim > > > > IMHO this is one of the best medical books written. Most medical > > schools have used this for years. > > > > If you have the latest edition what does it say about Conn's? > > > > The regulation of the circulation and volume chapters are the most > > important for understanding BP control. > > > > Quote Link to comment Share on other sites More sharing options...
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