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Re: Creatine Serum

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If it's real creatine you will retain some water. The ONLY real creatine is

creatine monohydrate. That " serum " you use is not doing you any good...hence

no water retention either. Just remember that your MD is a physician and

probably doesn't study sport's medicine nor keeps up on sports medicine

research. If you call EAS and ask for a copy of the Supplement Review, it is

a very thorough literature review of the current studies.,...especially on

creatine. Noted and footnoted are specific clinical studies of what works and

what doesn't. Creatine serum is sited as being a rip-off because creatine is

not stable in a liquid form.

I also go with what the pro's use....like football players and world class

athletes. MOST college teams, and ALL pro teams use CREATINE MONOHYDRATE.

That's good for me.

-

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I've been researching the creatine serum. My MD does not approve of Betagen

because of water retention. Here's the website for creatine serum:

http://www.creatine.com/

You can also read the FDA medwatch reports about adverse affects of powdered

creatine. http://vm.cfsan.fda.gov/~dms/aems.html#search

In the October 20, 1998 SN/AEMS Web Report there are a total of 2621 adverse

events.

In the October 20, 1998 SN/AEMS Web Report there are a total of 3451 products.

I read an article in a medical journal last week that said some of the NFL teams

have banned the use of powdered creatine because of adverse affects like muscle

cramping, nausea, and cardiac arrhythmia's.

Remember: each company will bad mouth the other and say their products are

superior over the competition. It's the nature of the beast.

Glenda

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Hi Glenda!

In your messages, you've mentioned a number of points that people would do

well to keep in mind, and I'm grateful that you have. It's certainly wise to

follow the advice of a sports-knowledgeable physician, to read and compare

research from different sources, and to educate oneself and to make up one's

own mind about which supplements to take. It's also exactly right to keep

one's health and well-being at the forefront of one's decision making.

You've also said the following though in your last two posts, and I want to

comment on this:

<<Of course each company is going to bad mouth each other's products. It's

just the nature of business.>>

You are right that some people can - and do - fall prey to the temptation to

say whatever they think will best promote the sales of their company. You are

also right that, given this possibility, it's wise to seek out independent

review of a company's claims.

That said, one of the greatest assets any company has is its reputation.

Those who give into the temptation to " say anything " to boost sales run a

huge risk. They may boost sales in the short run. But to the extent that such

unscrupulous vendors are proven to have made misleading claims, wise

customers will soon flock to more reputable sources for their products. It's

often impossible for a company to recover from such a damaged reputation -

and justly so. Wise business people therefore regard truth in advertising as

one of the most critical assets they possess with which to boost sales and

profits.

Furthermore, people have free will and are responsible for their own actions.

I don't consider it a valid excuse to say, " I said this, not because I

believe that it's true, but because I wanted to promote my company's

product. " This is a serious matter of personal and professional ethics, and I

regard it as critical that people be truthful and take responsibility for

what they say.

Consequently, although you are wise to caution people to look for second

opinions and independent information, I disagree that people are destined by

" the nature of business " to be untruthful. On the contrary, people are free

to say and do whatever they want. There certainly do exist countless, utterly

honest business people with laudable integrity who value their reputations,

not merely because of the competitive edge it gives them, but because they

pride themselves on being good people. Such people couldn't look themselves

in the mirror if they lived any way other than truthfully.

Regarding another element of the creatine serum vs. powder issue: it's a fact

that even highly educated experts will disagree sometimes about the safest,

most advisable supplementation strategy. Even assuming that a given company

is composed of honest individuals who treasure the truth and strive to behave

professionally and honorably in every aspect of their work - people are still

capable of honest error and honest difference of opinion. And people have a

right to make honest mistakes.

Again, all this underscores the wisdom of your advice that each person

examine the facts and make up one's own mind.

You strike me as a person who is doing the right things insofar as consulting

your physician, educating yourself and pursuing your fitness and

supplementation strategy wisely. And for that, I applaud you, both for the

good that you are doing for yourself, and for the good example that you are

setting.

Energetically,

Axel

Fitness and the Mind-Body Connection

an unofficial support site for Body-for-LIFErs

by and Cherita Axel

http://fitmind.home.mindspring.com/fmbconnection.html

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I trust my doc. He's the one who introduced me to BFL. Yes, he's certified in

sports medicine. He's also the medical director for a very large pro sports

franchise. I've read the literature and I have

the supplement review. My copy is copyrighted 1997 and a lot has changed since

that date.It's easy to pick out what literature you want to reference. I'm

guilty of that. I wrote the education module for

latex allergy for Abbott Laboratories and I only chose to use supportive

literature, not the " bashing " literature. Today's MedLine search with limits of

01-01-1997 to 10-03-2000 shows 911 articles. These

are not all peer reviewed literature but still a respected number of articles on

creatine monohydrate.

Of course each company is going to bad mouth each other's products. It's just

the nature of business. Just because EAS says that creatine serum is unstable

doesn't make that the truth. I just bought a new

Ford Taurus and guess what, when I went shopping for cars, I test drove a Chevy

Impala also and the Chevy dealer told me that Ford Taurus's were terrible cars.

Buyer beware. Only an educated consumer can decide what is best for them. If

Darra can use creatine serum, so can I. What a comeback for an over 30

woman.

Glenda

>

> Subject: Re: creatine serum

>

> If it's real creatine you will retain some water. The ONLY real creatine is

> creatine monohydrate. That " serum " you use is not doing you any good...hence

> no water retention either. Just remember that your MD is a physician and

> probably doesn't study sport's medicine nor keeps up on sports medicine

> research. If you call EAS and ask for a copy of the Supplement Review, it is

> a very thorough literature review of the current studies.,...especially on

> creatine. Noted and footnoted are specific clinical studies of what works and

> what doesn't. Creatine serum is sited as being a rip-off because creatine is

> not stable in a liquid form.

>

> I also go with what the pro's use....like football players and world class

> athletes. MOST college teams, and ALL pro teams use CREATINE MONOHYDRATE.

> That's good for me.

>

> -

>

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I won't use Betagen because of the possibility of water retention. I have high

blood pressure. Granted, it's much less severe than it was, but I am taking no

risks. I am NOT saying that Betagen is bad, it's just not for me. If there is

an alternative product with less side effects, I want to know about it. I also

won't use creatine monohydrate because of the MedWatch reports. I know it may

sound dumb to a lot of people, but I've spent my fair share of reading those

reports (especially latex related) and I automatically check these reports about

anything I decide to use, including medications or nutritionals. Sports

nutritionals

are not regulated by the FDA like medications are. It just makes sense to

investigate what you put into your body.

I am glad you've had no symptoms that have been reported to the FDA. I hope no

one ever has these type of problems. HMB is sold by itself and my husband and I

both use it.

Why are we bashing creatine serum? You don't need a glucose transport and you

don't need to increase your water intake.

As always, two sides to every issue.

glenda

> Glenda,

>

> Did your doctor recommend against because of the reports or because you took

> it and reacted in that manner? Part of the perceived problem is quality

> control, part is inadequate water consumption and part is taking higher

> doses than recommended. Without knowing the specifics of each case

> reported, it is difficult to draw a conclusion.

>

> I don't know anything about creatine serum, but I've taken over the last 9

> months, Phosphagen HP in loading and maintenance quantities per the

> directions, Betagen per the directions and stacked on top of a maintenance

> dosage of Phosphagen HP, a cheap off brand of Creatine Monohydrate powder at

> maintenance dosage, Labrada's Creatine Cooler at maintenance dosages, and

> now BetaGen at maintenance doses with Ribose stacked on top on weight

> training days. So far I have had none of the symptoms you describe.

>

> I understand that everyone is different and you need to listen to your body,

> but there have been a lot of tests on the safety and efficacy of creatine.

> Much like food, if you have a sensitivity you should cut the dosage or avoid

> it depending on the severity of your reaction. Several in this group have

> had negative reactions to the dosage recommended on the label. Some have

> discontinued, others have reduced the dosage. I have not heard of a severe

> allergic reaction, which I would attribute to the fact that creatine is

> present in everyone's body. Yet I do not discount that some individuals may

> not tolerate BetaGen. They should avoid its use since it is not required to

> have excellent results. In the test group over a 12 week period, I believe

> I recall that the group that took BetaGen experienced a 35-40% increase in

> lean gains vs. the control group. If you tolerate BetaGen and are looking

> to accelerate results, it can be a positive addition to your supplementation

> program.

>

> Also note that BetaGen is a stack of Creatine and HMB. Don't forget the HMB

> if you are choosing to not take BetaGen as HMB has been proven to be

> effective at preventing loss of lean muscle and enhance gains when taken as

> directed on the container as well as promote fat loss if taken in 6-12 doses

> spread over the day.

>

> Personally I would go with a vendor you trust that is committed to quality

> control and research. There are probably a half dozen or more that are very

> trustworthy, but some products have been tested and do not contain what is

> represented on the label.

>

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>

>

> Do you know of studies

> regarding serum creatine that establish its effectiveness and safety?

>

> -

Creatine serum is still creatine monohydrate and searching for relevant

articles: powder vs. serum doesn't exist. I even searched the data base at the

NIH to find out if there is such a study, but nutritionals are not listed. I

did find a review of literature from Belgium and I'll see if our MedLibrary

subscribes to

that Journal.

Best I can do without spending hours here at the keyboard.

Glenda

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Kit:

You can access the documents from that web site listed at this URL:

http://vm.cfsan.fda.gov/~dms/aems.html#search

Scroll down to the bottom of the page and search for creatine or you

can search by the ARMS numbers listed on that web site. You'll be

transferred to another page listing the ARMS number ( adverse event).

You can't access the complete file unless you file a Freedom of Information

Act. Once you do that, you have to pay for the copies and the shipping

to your home. Once you get copies of the documents you've requested,

there will be more information than what's on the web. ( You don't have

any shortcomings.......they just don't make it easy for anyone to obtain

the info!)

Seemed like the creatine serum folks were doing the bashing as they

put some

report of deaths from EAS products only on the net, without any details

allowing the public to reach a conclusion that those products caused the

deaths.

The FDA info is a voluntary reports unless people die and that's

mandatory and they (FDA) don't allow too many details to be on the

net. That's why you have to file a Freedom of Information Act.

Deaths are reported from other companies, not just EAS.

IMHO, that company should take out references to EAS off their website.

Reminds me of how a certain glove company plastered my name and phone number

all over their website and made reference to all of us who had filed suites

and said they were allotting $75 Million to fight us. Us against

the monolith. FDA documents are not protected by copyright,

so I guess they can do anything they wish.

Give me a couple of days to see if I can dig anything up about research.

I have some friends at NIH, I'll make a few inquiries. My elementary

kids are out today and tomorrow for parent/teacher conference. I

don't like to spend too much time on the computer while they are home.

I'm really curious about the research end also, especially when it comes

to women.

Glenda

Seemed like the creatine serum folks were doing the bashing as they

put some

report of deaths from EAS products only on the net, without any details

allowing the public to reach a conclusion that those products caused the

deaths. EAS invests heavily in research to ensure it is a responsible

manufacturer of sports supplements. I was not able to get to the

details of

what was reported and that may be due to my shortcomings in using the

internet. I welcome information about new products and old.

I'm an

information nut and pour through the studies myself and welcome the contrary

viewpoint. These views help to push innovation and make products

that are

safer and more effective. I object however to the tactics used by

the

makers of the serum creatine to gain market share. Just one view

point.

On the information side if you know of a source of studies related to serum

creatine and its effectiveness I'd love any guidance in how to get access

to

them.

Kit :=)

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  • 4 weeks later...

The problems these runners are having is not due to the creatine in the

creatine serum, especially if they had no problems with the powder. It is

very likely that the serum creatine has no creatine in it at all. Creatine

is very unstable in solution and will degrade to creatinine when left in

solution for a long period of time. No one has found a way to stabilize

creatine in solution. It is highly likely that these runners were not even

getting any creatine when they took the serum. I just got an email today

from Greenwalt, owner of the PowerStore, a discount internet

supplement store. He sent in the creatine serum for HPLC analysis and the

serum practically contained no creatine at all. The claim on the label says

2.5 g/5 ml but HPLC analysis revealed 0.0029 g/5 ml. Also, 0.005 g/5 ml of

creatinine was found in the product, and there should be no creatinine at

all.

It was also found that the product was 44% water and contained a large

amount of glycerol. Maybe the glycerol is having some effect on these

runners, if this is the same serum (from Muscle Marketing USA). Increased

plasma concentrations of glycerol may draw water from the interstital space

into the plasma and possible affect electrolyte balance in muscle tissue.

JK

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