[OEM] Reuters, OEM-J: Prenatal Pesticides Incr. Ped. Leukemia Risk (fwd)

[Guest guest]

Pesticides Raise Child Risk of Leukaemia - Study

UK: January 17, 2006

http://www.planetark.com/dailynewsstory.cfm/newsid/34510/story.htm

[Please visit the original website to view the whole article. - Mod.]

LONDON - Exposure to pesticides in the womb or as a child can double

the risk of developing acute leukaemia, French scientists said on

Tuesday.

They discovered that children born to women who used insecticides in

the home while pregnant and after the birth were nearly twice as

likely as other youngsters to develop leukaemia.

Even insecticidal shampoos to kill head lice raised the odds of the disease.

....

They found that youngsters exposed to fungicides and garden

insecticides had more than double the risk of the illness than other

children.

....

REUTERS NEWS SERVICE

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February 2006 OEM Preview Issue

No citation or abstract is available at the publisher's websire or at PubMed.

http://oem.bmjjournals.com/future/preview.shtml (obviously, not for long!)

likely soon (inferred):

http://oem.bmjjournals.com/content/vol63/issue2/

Household exposure to pesticides and risk of childhood acute leukaemia

Florence Menegaux, André Baruchel, Yves Bertrand, Brigitte Lescoeur,

Guy Leverger, Brigitte Nelken, Danièle Sommelet, Denis Hémon, and

Clavel

For review of their likely sources and data management:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=16289502 & query_hl=1 & itool=pubmed_docsum

Cancer Detect Prev. 2005;29(6):487-93. Epub 2005 Nov 9.

Maternal coffee and alcohol consumption during pregnancy, parental

smoking and risk of childhood acute leukaemia.

Menegaux F, Steffen C, Bellec S, Baruchel A, Lescoeur B, Leverger G,

Nelken B, Philippe N, Sommelet D, Hemon D, Clavel J.

INSERM, U170-IFR69 16, av. Vaillant-Couturier, F-94807 VILLEJUIF

Cedex, France.

Introduction: We investigated the role of maternal alcohol and coffee

drinking and parental smoking on the risk of childhood acute leukemia

in a multicenter case-control study. Methods: The study included 280

incident cases and 288 hospitalized controls, frequency matched with

the cases by age, gender and center. Data collection was completed by

face-to-face standardized interviews of the case and control mothers.

Results: An association with maternal alcohol consumption during

pregnancy was observed with acute lymphoid leukemia (ALL) (OR=2.0

[1.4-3.0]) and acute non-lymphoid leukemia (ANLL) (OR=2.6 [1.2-5.8]).

Maternal coffee consumption during pregnancy was associated with

childhood acute leukemia, ORs increasing in ALL with coffee

consumption (OR=1.1 [0.7-1.8], OR=2.4 [1.3-4.7] and OR=3.1 [1.0-9.5],

respectively, for </=3, 4-8 and >8cups/day). No association with

maternal smoking during pregnancy or parental smoking before or after

the index child's birth was observed. Discussion: Our results suggest

an association with maternal alcohol and coffee drinking during

pregnancy and call for further investigations. Besides, the present

study does not support the hypothesis of an increase in the risk of

childhood leukemia related to parental smoking.