Am I taking the correct dose of Inspra (epelerenone) ?

[Guest guest]

When I took Aldactone (spironolactone) (75 mg) I developed painful

gynocomastia. I switched to Midamor (amiloride) with inadequate

blood pressure control, and then I switched to Inspra (eplerenone.)

I have not had gynocomastia from the Inspra but I have had low sex

drive, difficulty with penile erection and ejaculation like I did on

Aldactone (spironolactone.)

Dr. Grim asked me for more information so here is a history of my

blood tests for 2007.

Here are my potassium, renin, aldosterone, blood pressure readings

and body weight for 2007:

2/09 4/30 7/26 7/30 8/16 8/28 9/28

Potassium 4.3 3.8 3.2 3.7 4.5 4.5 4.1

Renin 0.3 0.2 <0.2 0.2 n/a 0.2 n/a

Aldostero 42 24 n/a 20 n/a n/a n/a

Blood Pre 118/77 129/86 129/89 130/90 130/90 130/81 131/84

Weight 171 177 184 181 178 180 187

HGBA1c 5.6 5.8 n/a 6.0 n/a n/a 5.4

Glucose 89 83 105 84 95 117 112

LDL Chol 95 98 87 85 103 n/a 101

HDL Chol 37 42 40 41 42 n/a 45

Triglycer 83 107 149 94 146 n/a 195

Cholester 149 161 170 145 174 n/a 191

Current medications:

Inspra 100 mg twice a day

multi-vitamin

co-enzyme Q10 50 mg every other day

Omacor 1 gram in AM

Lipitor 10 mg in PM

Tricor 145 mg in PM

Cardura 1 mg in PM

Cymbalta 30 mg in PM

On 8/1/07 I increased Inspra from 75 mg twice a day to 100 mg twice

a day. Do you think I am on the correct dose of Inspra or should I

cut back to 75 mg twice a day?