Jump to content
RemedySpot.com

Re: Re: Spiro vs Aldactone - insulin & cholesterol, cinnamon & vinegar

Rate this topic


Guest guest

Recommended Posts

/For your mom, and others w/insulin, carb problems, Type II diabetes

(and bad cholesterol), look :/

http://diabetes.about.com/gi/dynamic/offsite.htm?zi=1/XJ & sdn=diabetes & cdn=health\

& tm=29 & f=

10 & su=p726.2.152.ip_p674.2.400.ip_p284.8.150.ip_ & tt=13 & bt=0 & bts=0 & zu=http%3A//ww\

w.ars.usda.gov/

Research/docs.htm%3Fdocid%3D8877

http://care.diabetesjournals.org/cgi/content/full/26/12/3215

http://diabetes.about.com/od/whatsonthehorizon/qt/cinnamon.htm

/and Basalmic (strong version of cider) vinegar was stumbled upon too -

back in the 1980's :/

http://www.diabetesincontrol.com/modules.php?name=News & file=article & sid=2475

http://www.apple-cider-vinegar-benefits.com/vinegar-and-diabetes.html

/and recently at AZ State Univ., study found it was same effects as

medications :/

http://researchmag.asu.edu/stories/vinegar.html

Dave

Farah Rahbar wrote:

> Thanks for remembering my mom. She is doing well. Her heart stopped last

> year suddenly but not before being able to dial 911. Thankfully she was

> revived and they put a pace maker on her. She had a pace maker put in few

> months earlier but her doctor said she needed a better device. Her diabetes

> has been out of control with all medications they tried so she is now

> on 1.5units insuline once a day and her sugar level is still a little

> high between

> 150-200 which she is not happy about.

>

> Best Wishes to you,

> Farah

>

> On Dec 31, 2007 12:44 PM, airlinerg <airlinerg@...> wrote:

>

>

>> Hi Farah,

>>

>> Nice to hear from you and Happy New Year!

>>

>> Since you did not do well with Inspra, it seems like Aldactone is

>> your only choice (or the generic Spironolactone.)

>>

>> How is your mom doing with her diabetes?

>>

>> Be well,

>>

>> Airlinerg

>>

>>

>>

>>> Dear all & Dr. Grim:

>>> Here is my two cents worth; I sent an email over a month ago

>>>

>> asking if

>>

>>> anyone on the group knows differences between Aldactone and its

>>>

>> generic

>>

>>> drug Spironolactone. I have been taking spiro for two yrs now

>>>

>> following my

>>

>>> diagnosis with PA. I took 100 mgs for the most of the 1st year and

>>>

>> reduced

>>

>>> to 75mgs thereafter. Just to give a little background about

>>>

>> myself, thats

>>

>>> all I take plus I DASH. My BP is well controlled with the two to

>>>

>> be under

>>

>>> 120/80 most of the time at home and always under 100/60+ at the

>>>

>> doctors

>>

>>> office.

>>> Last month, I decided to ask for Aldactone when I was up to renew

>>>

>> my

>>

>>> prescription so after taking Aldactone for about a month now, here

>>>

>> it goes,

>>

>>> a summery of the differences I have so far experienced:

>>>

>>>

>>> *Spironolactone, 75mgs, 25am, 50 pm + DASH*

>>>

>>> *Aldactone, 75mgs, 25 am, 50 pm + DASH*

>>>

>>> costs $5.00 for the bottle of pills to last a month

>>>

>>> additonal $65.00 that my insurance did not cover.

>>>

>>> Severe flushing and sweating during the days and at nights

>>>

>>> Initially didn't notice much difference-by 2nd week sweating was

>>>

>> gone 80-90%

>>

>>> Occasional heart palpitations

>>>

>>> Initially didn't notice much difference - Much less after the 2nd

>>>

>> week and

>>

>>> after a month its almost gone

>>>

>>> Severe muscle aches specially in my calves during nights and

>>>

>> mornings

>>

>>> muscle aches appear to be reduced-definitely no more in my calves

>>>

>>> - didn't experience this on spiro

>>>

>>> Wake up in mornings with numb little finger in my right hand - I

>>>

>> mean its

>>

>>> really numb with no feeling what so ever for a while

>>>

>>> -

>>>

>>> My right toes and foot go numb when I walk fast- should I be

>>>

>> concerned or

>>

>>> is this a K thing?

>>>

>>> Chest feeling like its being ripped apart into shreds before a

>>>

>> sweating

>>

>>> episode

>>>

>>> I no longer have this feeling - hooray

>>>

>>> Occasional feeling of mild nausea(I would say a 1-2 on a scale of

>>>

>> 0 to

>>

>>> 10)

>>>

>>> no more nausea :-)

>>>

>>> BP well controlled under 120/80 or lower

>>>

>>> BP is well controlled under 120/80 or lower

>>>

>>> occasional bouts of low salt episodes and have to do quick salt

>>>

>> loading to

>>

>>> feel better otherwise can not function or think mentally -- every

>>>

>> few days

>>

>>> Have not experienced any low salt episodes(days) in the past month

>>>

>> and have

>>

>>> maintained a low salt diet

>>>

>>>

>>>

>>> Feeling tired often

>>>

>>> pain in breasts and increased size

>>>

>>> certainly the pain is gone and I have lost a little though not

>>>

>> measurably on

>>

>>> the scale- my tops feel slightly looser

>>>

>>> My rings fit in my fingers tighter

>>>

>>> My rings are rather loose and come right off my fingers, so

>>>

>> obviously some

>>

>>> kind of less swelling

>>>

>>>

>>>

>>>

>>>

>>> Whats interesting is that last week I was traveling and forgot to

>>>

>> take the

>>

>>> Aldactone with me. But no worries, because I had a bottle of extra

>>>

>> Spiro

>>

>>> with me which I took. After the 2nd day all the side effects, in

>>>

>> particular

>>

>>> the weired feeling in my chest and the flushing came back.

>>>

>> Thankfully I

>>

>>> only took it for 4 days and am now back on Aldactone. Now the

>>>

>> challenge

>>

>>> remains to convince my doctor to write a prescription for

>>>

>> Aldactone instead

>>

>>> of spiro so the insurance can cover it. Otherwise I think I have

>>>

>> to invest

>>

>>> in Aldactone by paying $65 each month. The other challenge that

>>>

>> remains is

>>

>>> to do a blood test and get a measurement of the Aldosterone, Renin

>>>

>> and my K.

>>

>>> Once I do that I will keep you all posted but it will be a while

>>>

>> before I am

>>

>>> up for my next blood work.

>>>

>>> By the way, I have checked the chemical compounds of the two on-

>>>

>> line and

>>

>>> they both appear to be the same with minor differences in

>>>

>> ingredients.(I am

>>

>>> not a chemistry kind of a person so I leave this to some of you

>>>

>> experts in

>>

>>> analyzing the chemical compounds of the two :)

>>>

>>> Happy New Year to all of you,

>>>

>>> Farah

>>>

Link to comment
Share on other sites

Thanks Dave. I will let her know. I use balsamic vinegar and honey instead

of using salt in most foods I cook specially in stirfrys.

Farah

On Dec 31, 2007 1:05 PM, Dave <riothamus2@...> wrote:

> /For your mom, and others w/insulin, carb problems, Type II diabetes

> (and bad cholesterol), look :/

>

>

>

http://diabetes.about.com/gi/dynamic/offsite.htm?zi=1/XJ & sdn=diabetes & cdn=health\

& tm=29 & f=

> 10 & su=

>

p726.2.152.ip_p674.2.400.ip_p284.8.150.ip_ & tt=13 & bt=0 & bts=0 & zu=http%3A//www.ars.\

usda.gov/

> Research/docs.htm%3Fdocid%3D8877

>

> http://care.diabetesjournals.org/cgi/content/full/26/12/3215

>

> http://diabetes.about.com/od/whatsonthehorizon/qt/cinnamon.htm

>

> /and Basalmic (strong version of cider) vinegar was stumbled upon too -

> back in the 1980's :/

>

>

> http://www.diabetesincontrol.com/modules.php?name=News & file=article & sid=2475

>

> http://www.apple-cider-vinegar-benefits.com/vinegar-and-diabetes.html

>

> /and recently at AZ State Univ., study found it was same effects as

> medications :/

>

> http://researchmag.asu.edu/stories/vinegar.html

>

> Dave

>

> Farah Rahbar wrote:

> > Thanks for remembering my mom. She is doing well. Her heart stopped last

> > year suddenly but not before being able to dial 911. Thankfully she was

> > revived and they put a pace maker on her. She had a pace maker put in

> few

> > months earlier but her doctor said she needed a better device. Her

> diabetes

> > has been out of control with all medications they tried so she is now

> > on 1.5units insuline once a day and her sugar level is still a little

> > high between

> > 150-200 which she is not happy about.

> >

> > Best Wishes to you,

> > Farah

> >

> > On Dec 31, 2007 12:44 PM, airlinerg

<airlinerg@...<airlinerg%40grad.com>>

> wrote:

> >

> >

> >> Hi Farah,

> >>

> >> Nice to hear from you and Happy New Year!

> >>

> >> Since you did not do well with Inspra, it seems like Aldactone is

> >> your only choice (or the generic Spironolactone.)

> >>

> >> How is your mom doing with her diabetes?

> >>

> >> Be well,

> >>

> >> Airlinerg

> >>

> >>

> >>

> >>> Dear all & Dr. Grim:

> >>> Here is my two cents worth; I sent an email over a month ago

> >>>

> >> asking if

> >>

> >>> anyone on the group knows differences between Aldactone and its

> >>>

> >> generic

> >>

> >>> drug Spironolactone. I have been taking spiro for two yrs now

> >>>

> >> following my

> >>

> >>> diagnosis with PA. I took 100 mgs for the most of the 1st year and

> >>>

> >> reduced

> >>

> >>> to 75mgs thereafter. Just to give a little background about

> >>>

> >> myself, thats

> >>

> >>> all I take plus I DASH. My BP is well controlled with the two to

> >>>

> >> be under

> >>

> >>> 120/80 most of the time at home and always under 100/60+ at the

> >>>

> >> doctors

> >>

> >>> office.

> >>> Last month, I decided to ask for Aldactone when I was up to renew

> >>>

> >> my

> >>

> >>> prescription so after taking Aldactone for about a month now, here

> >>>

> >> it goes,

> >>

> >>> a summery of the differences I have so far experienced:

> >>>

> >>>

> >>> *Spironolactone, 75mgs, 25am, 50 pm + DASH*

> >>>

> >>> *Aldactone, 75mgs, 25 am, 50 pm + DASH*

> >>>

> >>> costs $5.00 for the bottle of pills to last a month

> >>>

> >>> additonal $65.00 that my insurance did not cover.

> >>>

> >>> Severe flushing and sweating during the days and at nights

> >>>

> >>> Initially didn't notice much difference-by 2nd week sweating was

> >>>

> >> gone 80-90%

> >>

> >>> Occasional heart palpitations

> >>>

> >>> Initially didn't notice much difference - Much less after the 2nd

> >>>

> >> week and

> >>

> >>> after a month its almost gone

> >>>

> >>> Severe muscle aches specially in my calves during nights and

> >>>

> >> mornings

> >>

> >>> muscle aches appear to be reduced-definitely no more in my calves

> >>>

> >>> - didn't experience this on spiro

> >>>

> >>> Wake up in mornings with numb little finger in my right hand - I

> >>>

> >> mean its

> >>

> >>> really numb with no feeling what so ever for a while

> >>>

> >>> -

> >>>

> >>> My right toes and foot go numb when I walk fast- should I be

> >>>

> >> concerned or

> >>

> >>> is this a K thing?

> >>>

> >>> Chest feeling like its being ripped apart into shreds before a

> >>>

> >> sweating

> >>

> >>> episode

> >>>

> >>> I no longer have this feeling - hooray

> >>>

> >>> Occasional feeling of mild nausea(I would say a 1-2 on a scale of

> >>>

> >> 0 to

> >>

> >>> 10)

> >>>

> >>> no more nausea :-)

> >>>

> >>> BP well controlled under 120/80 or lower

> >>>

> >>> BP is well controlled under 120/80 or lower

> >>>

> >>> occasional bouts of low salt episodes and have to do quick salt

> >>>

> >> loading to

> >>

> >>> feel better otherwise can not function or think mentally -- every

> >>>

> >> few days

> >>

> >>> Have not experienced any low salt episodes(days) in the past month

> >>>

> >> and have

> >>

> >>> maintained a low salt diet

> >>>

> >>>

> >>>

> >>> Feeling tired often

> >>>

> >>> pain in breasts and increased size

> >>>

> >>> certainly the pain is gone and I have lost a little though not

> >>>

> >> measurably on

> >>

> >>> the scale- my tops feel slightly looser

> >>>

> >>> My rings fit in my fingers tighter

> >>>

> >>> My rings are rather loose and come right off my fingers, so

> >>>

> >> obviously some

> >>

> >>> kind of less swelling

> >>>

> >>>

> >>>

> >>>

> >>>

> >>> Whats interesting is that last week I was traveling and forgot to

> >>>

> >> take the

> >>

> >>> Aldactone with me. But no worries, because I had a bottle of extra

> >>>

> >> Spiro

> >>

> >>> with me which I took. After the 2nd day all the side effects, in

> >>>

> >> particular

> >>

> >>> the weired feeling in my chest and the flushing came back.

> >>>

> >> Thankfully I

> >>

> >>> only took it for 4 days and am now back on Aldactone. Now the

> >>>

> >> challenge

> >>

> >>> remains to convince my doctor to write a prescription for

> >>>

> >> Aldactone instead

> >>

> >>> of spiro so the insurance can cover it. Otherwise I think I have

> >>>

> >> to invest

> >>

> >>> in Aldactone by paying $65 each month. The other challenge that

> >>>

> >> remains is

> >>

> >>> to do a blood test and get a measurement of the Aldosterone, Renin

> >>>

> >> and my K.

> >>

> >>> Once I do that I will keep you all posted but it will be a while

> >>>

> >> before I am

> >>

> >>> up for my next blood work.

> >>>

> >>> By the way, I have checked the chemical compounds of the two on-

> >>>

> >> line and

> >>

> >>> they both appear to be the same with minor differences in

> >>>

> >> ingredients.(I am

> >>

> >>> not a chemistry kind of a person so I leave this to some of you

> >>>

> >> experts in

> >>

> >>> analyzing the chemical compounds of the two :)

> >>>

> >>> Happy New Year to all of you,

> >>>

> >>> Farah

> >>>

>

>

Link to comment
Share on other sites

If you mother can DASH she will help her DM.

Are you of Indian (Asian) heritage. I have just advanced a Ho that the

major health problems in Indians is a result of their history or starvation and

salt deficiency. I think I sent a copy to everyone about a year ago. I just

gave a talk in Hyderabad and Agra and Delhi on it.

May your pressure be low!

Clarence E. Grim, BS, MS, MD

Senior Consultant to Shared Care Research and Consulting, Inc.

(sharedcareinc.com)

Clinical Professor of Internal Medicine and Epidemiology Med. Col. WI

Clinical Professor of Nursing, Univ. of WI, Milwaukee

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

**************************************

See AOL's top rated recipes

(http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004)

Link to comment
Share on other sites

Please always do a pubmed search on topic like this first. eg. most recent

article on cinnamon.

Med Oral Patol Oral Cir Bucal.

May your pressure be low!

Clarence E. Grim, BS, MS, MD

Senior Consultant to Shared Care Research and Consulting, Inc.

(sharedcareinc.com)

Clinical Professor of Internal Medicine and Epidemiology Med. Col. WI

Clinical Professor of Nursing, Univ. of WI, Milwaukee

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

2007 Oct 1;12(6):E440-4. Links

Cinnamon products as a possible etiologic factor in orofacial granulomatosis.

Endo H, Rees TD.

Department of Periodontology, Nihon University, School of Dentistry at

Matsudo, Chiba, Japan. endo.hiroyasu@....

OBJECTIVES: It has been reported that clinical changes due to

hypersensitivity reactions to various foods, preservatives, and oral hygiene

products may be

consistent with the characteristic signs of orofacial granulomatosis (OFG).

The objective of this study was to examine 37 well-documented cases of

cinnamon-induced contact stomatitis for clinical and histological features

consistent

with a diagnosis of OFG. STUDY DESIGN: We reviewed the records of the 37 cases

to screen them for the clinical and histopathologic features of OFG. RESULTS:

Twelve patients showed clinical characteristics of OFG. The most commonly

affected site was the gingiva. Focal non-caseating, epitheloid granulomas were

observed in four histologic specimens. Multinucleated giant cells were observed

in an additional four cases. CONCLUSIONS: Although OFG may have multiple

etiologies, it is clear that, in some instances, a hypersensitivity reaction to

cinnamon products can elicit lesions consistent with OFG.

J Med Assoc Thai. 2006 Sep;89 Suppl 3:S200-5.

Related Articles, Links

The effect of cinnamon cassia powder in type 2 diabetes mellitus.

Suppapitiporn S, Kanpaksi N, Suppapitiporn S.

Department of Outpatients, King Chulalongkorn Memorial Hospital, Bangkok

10330, Thailand.

BACKGROUND: Type 2 diabetes is a chronic metabolic disorder and the incidence

of cardiovascular is increased two- to fourfold in its complications.

Cinnamon is expected to have some degree of anti-diabetic efficacy without

troublesome side effects. The objective of the present study was to investigate

the

anti-diabetic effect of cinnamon cassia powder in type 2 diabetic patients

MATERIAL AND METHOD: Sixty type 2 diabetic patients were randomized either 1.5

g/d of

cinnamon cassia powder or placebo. Both groups were in combination with their

current treatment (metformin or sulfonylurea) according to single blind

randomized, placebo-control trial in a 12-week period. Efficacy was evaluated by

HbA1c fasting plasma glucose, Lipid profile, BUN, creatinine, liver function

test and adverse effects were recorded. RESULTS: After a 12-week period, HbA1c

was decreased similarly in both groups from 8.14% to 7.76% in the cinnamon group

and from 8.06% to 7.87% in the placebo group. This was not found

statistically significantly different. However the proportion of patients

achieving HbA1c <

or = 7% was also greater in patients receiving cinnamon compared with

patients receiving placebo, nevertheless, it was not found statistically

significantly different (35% vs 15%, x2 = 3.14, p > 0.05). No significant

intergroup

differences were observed in lipid profile, fasting plasma glucose except in

SGOT

27.1 (8.75) to 22.1 (5) in cinnamon group and 24.08 (8.5) to 23.63 (8.88) in

the placebo group (p = 0.001). CONCLUSION: The cinnamon cassia powder 1.5 g/d

did not have any significant difference in reducing fasting plasma glucose,

HbA1c and serum lipid profile in type 2 diabetes patients who had mean fasting

plasma glucose 154.40 +/- 24.72 mg/dl.

Am J Clin Nutr. 2007 Jun;85(6):1552-6.

Related Articles, Links

Effect of cinnamon on postprandial blood glucose, gastric emptying, and

satiety in healthy subjects.

Hlebowicz J, Darwiche G, Björgell O, Almér LO.

Department of Medicine, Malmö University Hospital, University of Lund, Lund,

Sweden. joanna.hlebowicz@...

BACKGROUND: Previous studies of patients with type 2 diabetes showed that

cinnamon lowers fasting serum glucose, triacylglycerol, and LDL- and total

cholesterol concentrations. OBJECTIVE: We aimed to study the effect of cinnamon

on

the rate of gastric emptying, the postprandial blood glucose response, and

satiety in healthy subjects. DESIGN: The gastric emptying rate (GER) was

measured

by using standardized real-time ultrasonography. Fourteen healthy subjects

were assessed by using a crossover trial. The subjects were examined after an

8-h

fast if they had normal fasting blood glucose concentrations. GER was

calculated as the percentage change in the antral cross-sectional area 15-90 min

after ingestion of 300 g rice pudding (GER1) or 300 g rice pudding and 6 g

cinnamon (GER2). RESULTS: The median value of GER1 was 37%, and that of GER2 was

34.5%. The addition of cinnamon to the rice pudding significantly delayed

gastric

emptying and lowered the postprandial glucose response (P < 0.05 for both).

The reduction in the postprandial blood glucose concentration was much more

noticeable and pronounced than was the lowering of the GER. The effect of

cinnamon

on satiety was not significant. CONCLUSIONS: The intake of 6 g cinnamon with

rice pudding reduces postprandial blood glucose and delays gastric emptying

without affecting satiety. Inclusion of cinnamon in the diet lowers the

postprandial glucose response, a change that is at least partially explained by

a

delayed GER.

Diabetes Care. 2007 Apr;30(4):813-6.

Related Articles, Links

The effect of cinnamon on A1C among adolescents with type 1 diabetes.

Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM.

Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire,

USA.

OBJECTIVE: The purpose of this study was to determine the effect of cinnamon

on glycemic control in adolescents with type 1 diabetes. RESEARCH DESIGN AND

METHODS: Using a prospective, double-blind, placebo-controlled design, 72

adolescent type 1 diabetic subjects were treated in an outpatient setting with

cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. A1C, total

daily insulin intake, and adverse events were recorded and compared between

groups. RESULTS: There were no significant differences in final A1C (8.8 vs.

8.7, P

= 0.88), change in A1C (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or

number of hypoglycemic episodes between the cinnamon and placebo arms.

CONCLUSIONS: Cinnamon is not effective for improving glycemic control in

adolescents

with type 1 diabetes.

Also another 100 + articles. Note that even cinnamon is not without side

effects.

**************************************

See AOL's top rated recipes

(http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004)

Link to comment
Share on other sites

In a message dated 1/2/08 3:45:23 AM, riothamus2@... writes:

> Farah Rahbar wrote:

> >

> > Actually I am of Persian background, we are not considered South Asian.

> >

> > Are you familiar with the South Asian Heart Center? El Camino Hospital in

> > Los Altos, CA, started this program after noticing that many of their

> > patients with sudden heart attacks and strokes were younger generation of

> > Indian backgrounds in their 40's or younger. Way too young to develop

> > heart

> > disease. Since a large population of people from India live in this area,

> > they funded this program to encourage South Asians to undergo advance

> > tests

> > not normally done in regular blood tests to identify early Coronary

> > disease.

>

My hypothesis suggests they need to DASH and that would take care of most of

the problem. Lo sodium is almost never recommended for Indian pts as their

Drs dont believe it is relavent.

As an example of this less than 5% of BP Rx for Indians are for diuretics.

Pharms seem to own Indian Drs at least over there.

May your pressure be low!

Clarence E. Grim, BS, MS, MD

Senior Consultant to Shared Care Research and Consulting, Inc.

(sharedcareinc.com)

Clinical Professor of Internal Medicine and Epidemiology Med. Col. WI

Clinical Professor of Nursing, Univ. of WI, Milwaukee

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

**************************************

See AOL's top rated recipes

(http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004)

Link to comment
Share on other sites

Join the conversation

You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...