Domino Effect

[Guest guest]

Greetings

Having a gluclose reading that was rock steady 111 - 115 until

sometime in the past 6 months it has risen to 192.

Can or does the PA start to affect other systems when the PA itself

has gone awry.

My annual MRI was DEC05 and showed no change.

I'm having the oral gluclose test and thyroid panel on Tues.

There has been no change in my living conditions other than cutting

back on salt.

And the weight gain started when I was switched from Spiro to Inspra.

Not to say that that was a trigger but just a observation in timing.

One other note is that a 24hr BP monitor in FEB06 showed that my BP

was all over the place when I was awake and then fell sharply when I

went to sleep.

A MAY06 monitoring showed that my PB was fairly level but failed to

go down when I slept.

Comments?

Gordon

[Guest guest]

Gordon,

I've developed the same problem, in the past year my

glucose levels have risen. My 2 HR GTT from 8 months

ago was:

Fasting - 120 (normal 65-110)

1 HR - 222 (normal <200)

2 HR - 179 (normal 100-140)

Not too bad but still in the range to officially

classify me as diabetic. Since this time I've

managed, with great difficulty, to lose 22 pounds and

it has dramatically helped my blood sugar. I haven't

repeated the GTT but fasting BS and 2 HR PPBS have all

been in normal range and Hgb A1C was 5. I have all

the classic symptoms of Metabolic Syndrome:

*Increased waist circumference (>=102 cm in men and

>=88 cm in women), indicating central obesity

*Elevated triglycerides (>=150 mg/dL or 1.7 mmol/l)

*Decreased HDL cholesterol (<40 mg/dL or 1.03 mmol/l

for men, <50 mg/dL or 1.29 mmol/l for women)

*Blood pressure above 130/85 or active treatment for

hypertension

*Glucose levels above 100 mg/dL (5.6 mmol/l) or active

treatment for hyperglycemia

I need to lose another 30 pounds but it's an ongoing

daily battle. It's very easy for me to gain weight but

very hard to lose it. I've discovered that if I

consume more than 1500 calories/day I will gain.

Since my father and his mother were diabetic I may

just be developing the late-onset type that runs in my

family. But there's nobody in my family, diabetic or

not, who has the central, abdominal obesity that I

have. There are studies that link high levels of

aldosterone and PA to Metabolic Syndrome. There are

several on pubmed, here's just a few below. It would

be interesting to see how many of us here have

symptoms of Metabolic Syndrome.

a

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ct & list_uids=16291704 & query_hl=2 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ct & list_uids=12875476 & query_hl=2 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ct & list_uids=12642008 & query_hl=2 & itool=pubmed_docsum

--- gnenjnj <syracuse46567@...> wrote:

> Greetings

>

> Having a gluclose reading that was rock steady 111 -

> 115 until

> sometime in the past 6 months it has risen to 192.

>

> Can or does the PA start to affect other systems

> when the PA itself

> has gone awry.

>

> My annual MRI was DEC05 and showed no change.

>

> I'm having the oral gluclose test and thyroid panel

> on Tues.

>

> There has been no change in my living conditions

> other than cutting

> back on salt.

>

> And the weight gain started when I was switched from

> Spiro to Inspra.

>

> Not to say that that was a trigger but just a

> observation in timing.

>

> One other note is that a 24hr BP monitor in FEB06

> showed that my BP

> was all over the place when I was awake and then

> fell sharply when I

> went to sleep.

>

> A MAY06 monitoring showed that my PB was fairly

> level but failed to

> go down when I slept.

>

> Comments?

> Gordon

>

>

>

>

>

>

>