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Re: Non-suppressible Aldosterone

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Most have early primary aldo from a tumor or hyperplasia that does not show up on scan. see my article for a review. Is spiro is helping a lot then his confirms it.

May your pressure be low!

C.E. Grim, B.S., M.S., M.D.

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

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Yes, Spiro is a lot of help for a year now. If this is early primary

aldo, how should I address this concern? If no tumor nor hyperplasia

is noted on a scan, is surgery still one of my options? I would rather

prefer drugs to an operation.

>

> Most have early primary aldo from a tumor or hyperplasia that does

not show

> up on scan. see my article for a review. Is spiro is helping a

lot then his

> confirms it.

>

>

>

> May your pressure be low!

>

> C.E. Grim, B.S., M.S., M.D.

> Specializing in Difficult to Control High Blood Pressure

> and the Physiology and History of Survival During

> Hard Times and Heart Disease today.

>

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In a message dated 7/25/06 8:41:15 PM, bayabas76@... writes:

Yes, Spiro is a lot of help for a year now. If this is early primary

aldo, how should I address this concern? If no tumor nor hyperplasia

is noted on a scan, is surgery still one of my options? I would rather

prefer drugs to an operation.

I only recommend surgery if drugs fail and spiro has been around for nearly 45 years. DASHing will help a lot.

Remember-aldo must have excess salt to do its damage. Not excess salt no HTN, No DM no fibrosis etc.

As we dont know what causes the hyperplasia-->ademoa(s) we dont yet know how to specifically treat or prevent it. Likely some genes at work-badly.

May your pressure be low!

C.E. Grim, B.S., M.S., M.D.

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

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Surgery would be an option if your AVS pointed to only one side being involved. But if DASHing and spriro(or Inspra) controls BP and K. I do not recommmend surgery. Many men will get painful breasts on sprio and this seems not to be a problem with Inspra.

So DASH as hard as you can and use as little Spiro as you can or switch to Inspra. Work closely with your Dr. and I am happy to consult with him or her by email if there are questions.

May your pressure be low!

C.E. Grim, B.S., M.S., M.D.

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

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>

> Surgery would be an option if your AVS pointed to only one side being

> involved.

I have no idea which side has early aldo. I have not met a doc here in

my country with reliable record on AVS.

But if DASHing and spriro(or Inspra) controls BP and K. I do not

> recommmend surgery. Many men will get painful breasts on sprio and

this seems not

> to be a problem with Inspra.

Yes, both my breasts are painful to touch especially the nipples area.

I also noticed slight enlargement. Inspra is not available here in the

Philippines.

>

>

> So DASH as hard as you can and use as little Spiro as you can or

switch to

> Inspra. Work closely with your Dr. and I am happy to consult with

him or her

> by email if there are questions.

>

Spiro 100mg bid in combination with a ccb is working for the time

being. No health team is attending my case now. I have tried all here

in my city, they all failed to recognize PA.

>

> May your pressure be low!

>

> C.E. Grim, B.S., M.S., M.D.

> Specializing in Difficult to Control High Blood Pressure

> and the Physiology and History of Survival During

> Hard Times and Heart Disease today.

>

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You might see if you can order Inspra over the internet. Talk to a Pharmacist there to see if they can buy it for you-with a prescription of course. Is there a medical school in you area? This would be a good place to try to find someone who knows PA.

Painful nipples likely due to Spiro. You can try to back down the spiro slowly and see if DASHing (no fish sauce) helps as well.

May your pressure be low!

C.E. Grim, B.S., M.S., M.D.

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

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> Painful nipples likely due to Spiro.

When I had gout, I took Colchicine. An overdose was indicated by

severe diarrhea. Are painful breasts and nipples in me caused by

overdose of Spiro? If I back down on Spiro, I am afraid my bp might

shoot up.

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In a message dated 7/30/06 5:58:18 AM, bayabas76@... writes:

> Painful nipples likely due to Spiro.

When I had gout, I took Colchicine. An overdose was indicated by

severe diarrhea.

This means you got up to a good dose and should stop.

Are painful breasts and nipples in me caused by

overdose of Spiro?

Not an overdose, just a side effect. In my experience once this develops it is not possible to find a dose low enough to not have it. However it is always worth a slow step down to see if you can find a dose that controls BP but does not cause mastodynia-medical name for painful breasts.

If I back down on Spiro, I am afraid my bp might

shoot up.

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In a message dated 8/3/06 11:52:20 AM, bayabas76@... writes:

It took me a while to learn to accept that my non-suppressible

aldosterone is most likely caused by a genetic glitch. Since science

has not found a cure yet, it felt like a death sentence. Nothing left

but wait, is it?

Don't forget that life is a sexually transmitted uniformly fatal disease.

May your pressure be low!

C.E. Grim, B.S., M.S., M.D.

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

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It took me a while to learn to accept that my non-suppressible

aldosterone is most likely caused by a genetic glitch. Since science

has not found a cure yet, it felt like a death sentence. Nothing left

but wait, is it?

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In a message dated 8/4/06 9:56:31 PM, bayabas76@... writes:

amexperimenting with reducing Spiro to 100mg in the morning and 50mg

in the evening for three days now. Less pain in the breasts, but bp

seems to get out of control.

Might try going down slower and work diligently on the lower sodium intake (DASH)

May your pressure be low!

C.E. Grim, B.S., M.S., M.D.

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

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> Don't forget that life is a sexually transmitted uniformly fatal

disease.

>

I amexperimenting with reducing Spiro to 100mg in the morning and 50mg

in the evening for three days now. Less pain in the breasts, but bp

seems to get out of control.

Wow, it must be a great title of a bestseller...Life is a Death

Sentence...by me, if only I knew how to write a book.

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