Re: Can Inspra Raise Triglycerides?

[Guest guest]

Hi Mike:

I was on Spiro for a month, then on Inspra for a month, then

switched back to one month of spiro before testing my lipids. My

triglycerides skyrocketed, actually my trig. quadrupled from what it

was 3 months prior to taking the meds. Until now I was blaming spiro

for it. Or perhaps they both raise the trig.

Farah

>

> The literature definatley says it can. I haven't had mine checked

in

> a long time. the reason I ask is that I have orthostatic

hypertension-

> -my blood pressure can skyrocket from sitting to standing, and one

of

> the causes listed in the literature is high triglycerides. I have

> prickling and tingling in my legs, but no neuropathy that a doctor

can

> find and sugars have been quite good (including a 103 only 1 hour

> after eating mac and cheese!). I asked my doc to do a lipid

panel, he

> dismissed me (I'm a young guy and have always had low cholesterol,

but

> triglycerides just above the upper limit of normal).

>

> So, am I looking for a zebra, or could inspra have made my

> triglycerides shoot up to seriously high, pre-diabetic levels? In

> other words, is it liely that inspra could cause a rise in

> triglycerides that would be worth noting? The literature says

yes,

> what does the real world say, though.

>

> Thanks,

>

> Mike

>

[Guest guest]

I was on Sprironolactone(100mg):

trig was border line, 170

choles was 200,

My doctor told me I had to take statins drugs.

On Niaspan and Spiro for 1 month, then Inspra one month, then spiro

1 month:

Choles 189

Trig 520

On Lipitor and Spiro:

Could not telerate Lipitor after 3 weeks of not being consistent

and feeling very sick and tired added fish oil(2spoons/day) stopped

Lipitor

Trig =150

With spiro I was walking minimum 3 miles everyday, 4-5 days/wk

trying to get back in shape.

On Lipitor could not even walk half a block my muscles were so weak

and I felt sick all the time so I stopped.

Diet: Dashing with low glycemic carbs very rarely red meat and

mainly white chicken and fish

Weight: 115 lbs, bmi=20, height: 5.2,

I definitely put the blame on spiro and Inspra.

Farah

>

> Could you all send us your triglycerides and all meds you were

taking when

> they were measured ---and your weight and what type of diet you

were on? We

> can pool the results and see what turns up.

>

>

>

> May your pressure be low!

>

> CE Grim, BS(Chem/Math), MS(Biochem), MD.

> Board Certified in Internal Medicine, Geriatrics and Hypertension

> Former Epidemiologic Intelligence Services Officer (Lt. Comdr.),

CDC

> Specializing in Difficult to Manage High Blood Pressure

> Clinical Professor of Medicine, Medical College of Wisconsin

>

[Guest guest]

>

> Could you all send us your triglycerides and all meds you were

taking when

> they were measured ---and your weight and what type of diet you

were on? We

> can pool the results and see what turns up.

>

Here is mine:

Medicines taken at the time:

Spironolactone 50mg bid, Lacidipine, Furosemides since August 2005.

Triglycerides 1.16mmol/L (105.45 mg/dL)

Cholesterol 250mg/dL

LDL Cholesterol 183.08 mg/dL

Weight (naked): 84 kilos. Height: 5ft 9in. Male. 46 years old.

Diet is lo salt fish. rice, some fastfood type fried chicken. Lo-fat

milk for breakfast.

Two weeks ago, a new doctor has taken me off Furosemides. Replaced

lacidipine with felodipine. Increased my spiro to 100mg bid. He added

allopurinol and crestor(statin)

[Guest guest]

> Have you had gout? (that is what allopurinol is for)

>

Yes, I am having recurrent gout attacks which is less frequent now

after having been pulled off Furosemides. My BUN and creatinine has

also improved in two weeks. Here are my recent readings: BUN 6.00

mmol/L, CREA 152umol/L, Sodium 138mmol/L, Potassium 4.00 mmol/L. My

readings two weeks ago for comparison: BUN 7.60mmol/L, CREA 169 umol/L,

Na 137 mmol/L, K 3.80mmol/L.

Spiro is now at 100mg bid, Metoprolol is also taken off.My only other

antihypertensive is felodipine 10mg once a day.

Regards.

[Guest guest]

> Should be feeling a bit better off these meds? Hope the BP holds.

DASHing

> is really important.

>

Is the Spiro100mg bid safe as a long-term therapeutic regimen if my bp

stays good? Is there a possibility of tapering down the dosage

eventually? My doctor says no to lowering it.

[Guest guest]

My triglycerides were a little high about 235 during my annual

physical about 3 months after my bp first started going up. They

weren't checked for another couple of years and by then it was up to

500. At the time, I wasn't on either Inspra or Spiro. My

cholesterol has always been good and last year when I was taking 20

mg Lipitor a day, I had my lipids checked and the bad cholesterol was

19 which my dr said was too low. I was also having swelling and

numbness in my hands especially at night. She put me back on 10 mg

and the swelling went away. The numbness comes back at times. I

can't take any of the drugs for triglycerides because they cause more

pain in my feet. After I found out that I had hyperaldosterone, I

thought it was connected to the triglycerides since they jumped up so

suddenly. I had been walking before my bp jumped up and then quit

but surely that wouldn't have caused my triglyceride level to double.

Fran

> >

> > The literature definatley says it can. I haven't had mine

checked

> in

> > a long time. the reason I ask is that I have orthostatic

> hypertension-

> > -my blood pressure can skyrocket from sitting to standing, and

one

> of

> > the causes listed in the literature is high triglycerides. I

have

> > prickling and tingling in my legs, but no neuropathy that a

doctor

> can

> > find and sugars have been quite good (including a 103 only 1 hour

> > after eating mac and cheese!). I asked my doc to do a lipid

> panel, he

> > dismissed me (I'm a young guy and have always had low

cholesterol,

> but

> > triglycerides just above the upper limit of normal).

> >

> > So, am I looking for a zebra, or could inspra have made my

> > triglycerides shoot up to seriously high, pre-diabetic levels?

In

> > other words, is it liely that inspra could cause a rise in

> > triglycerides that would be worth noting? The literature says

> yes,

> > what does the real world say, though.

> >

> > Thanks,

> >

> > Mike

> >

>

[Guest guest]

Both my father and brother have high cholesterol. I didn't have low

HDL before my doctor increased my Lipitor to 20 mg. I tried lowering

tri by diet and exercise and the best I could get was 375. I don't

eat a lot of fat, I cannot tolerate fat on meat, it makes me want to

throw up. I think it is the consistancy or something. I rarely eat

fried food and when I cook with oil, I use canola oil. I don't do

the DASH diet, I don't believe in it. Do you have any statistics on

how many people in this group have tried it and had lower bp as a

result? My NA is at the bottom of the range and CL is below the

range. My K is 4.3 and was higher before I kept going off of Spiro

for testing.

Fran

>

>

> In a message dated 5/17/06 3:51:27 PM, frand.2@... writes:

>

>

> > After I found out that I had hyperaldosterone, I

> > thought it was connected to the triglycerides since they jumped

up so

> > suddenly.  I had been walking before my bp jumped up and then quit

> > but surely that wouldn't have caused my triglyceride level to

double.

> >

> >

>

> Tris are most sensitive to diet and with your drug reaction problem

Hx I

> would really work on that first. Your HDL is very low and I would

repeat it just

> to see. Have others in your family been checked for very low

HDL.

>

>

>

> May your pressure be low!

>

> CE Grim, BS(Chem/Math), MS(Biochem), MD.

> Board Certified in Internal Medicine, Geriatrics and Hypertension

> Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

> Specializing in Difficult to Manage High Blood Pressure

> Clinical Professor of Medicine, Medical College of Wisconsin

>

[Guest guest]

Triglycerides can be lowered by reducing your carbohydrates such as

breads and sugary stuff rather than fat & increasing your protein

such as fish and chicken. Increasing your omega 3 & 6( fish oil and

oils from the nuts) can actually reduce your trig.

> >

> >

> > In a message dated 5/17/06 3:51:27 PM, frand.2@ writes:

> >

> >

> > > After I found out that I had hyperaldosterone, I

> > > thought it was connected to the triglycerides since they

jumped

> up so

> > > suddenly.  I had been walking before my bp jumped up and then

quit

> > > but surely that wouldn't have caused my triglyceride level to

> double.

> > >

> > >

> >

> > Tris are most sensitive to diet and with your drug reaction

problem

> Hx I

> > would really work on that first. Your HDL is very low and I

would

> repeat it just

> > to see. Have others in your family been checked for very low

> HDL.

> >

> >

> >

> > May your pressure be low!

> >

> > CE Grim, BS(Chem/Math), MS(Biochem), MD.

> > Board Certified in Internal Medicine, Geriatrics and Hypertension

> > Former Epidemiologic Intelligence Services Officer (Lt. Comdr.),

CDC

> > Specializing in Difficult to Manage High Blood Pressure

> > Clinical Professor of Medicine, Medical College of Wisconsin

> >

>

[Guest guest]

One doctor told me to take fish oil instead of Lipitor so I tried it

for a while. My triglycerides went back up to 500.

> > >

> > >

> > > In a message dated 5/17/06 3:51:27 PM, frand.2@ writes:

> > >

> > >

> > > > After I found out that I had hyperaldosterone, I

> > > > thought it was connected to the triglycerides since they

> jumped

> > up so

> > > > suddenly.  I had been walking before my bp jumped up and then

> quit

> > > > but surely that wouldn't have caused my triglyceride level to

> > double.

> > > >

> > > >

> > >

> > > Tris are most sensitive to diet and with your drug reaction

> problem

> > Hx I

> > > would really work on that first. Your HDL is very low and I

> would

> > repeat it just

> > > to see. Have others in your family been checked for very low

> > HDL.

> > >

> > >

> > >

> > > May your pressure be low!

> > >

> > > CE Grim, BS(Chem/Math), MS(Biochem), MD.

> > > Board Certified in Internal Medicine, Geriatrics and

Hypertension

> > > Former Epidemiologic Intelligence Services Officer (Lt.

Comdr.),

> CDC

> > > Specializing in Difficult to Manage High Blood Pressure

> > > Clinical Professor of Medicine, Medical College of Wisconsin

> > >

> >

>

[Guest guest]

At Mayo clinic every floor was supplied with samples of Dash

booklets they were giving free and in their library available to

public.

Last time when my mom was hospitalized in norht. Cal. I noticed that

the educational channel of the hospital was heavily promoting the

dash diet and giving sample cooking instructions.

You go to your doctor and tell him/her you are on the Dash diet,

he'll give you a strange look as if he/she has no idea what you are

talking about. Then give you a lecture on how you need to cut your

salt intake.(Dah..!)

Farah

>

> > im one of them!!!

> > thanks mark

> >> Re: Re: Can Inspra Raise

Triglycerides?

> >>

> >>

> >> In a message dated 5/19/06 1:13:56 AM, farahbar@... writes:

> >>

> >>

> >>> I don't do

> >>> > the DASH diet, I don't believe in it.  Do you have any

statistics

> >>> on

> >>> > how many people in this group have tried it and had lower bp

as a

> >>> > result? 

> >>

> >>

> >> Get the book and read it and decide for your self.

> >>

> >> You can always play the game You bet your life!

> >>

> >>

> >>

> >> May your pressure be low!

> >>

> >> CE Grim, BS(Chem/Math), MS(Biochem), MD.

> >> Board Certified in Internal Medicine, Geriatrics and

Hypertension

> >> Former Epidemiologic Intelligence Services Officer (Lt.

Comdr.), CDC

> >> Specializing in Difficult to Manage High Blood Pressure

> >> Clinical Professor of Medicine, Medical College of Wisconsin

> >>

>