Re: Re: Can Inspra Raise Triglycerides?

May 13, 2006

Could you all send us your triglycerides and all meds you were taking when they were measured ---and your weight and what type of diet you were on? We can pool the results and see what turns up.

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 13, 2006

I pub meded sprironolactone and triglycerides and it would appear the effect is neutral to a tendency to lower tris.

Might depend on how volume expanded you were before the sprio--which would lower tri and then aldo antagon would lower the volume and increase tris.

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 14, 2006

In a message dated 5/13/06 2:43:03 PM, farahbar@... writes:

With spiro I was walking minimum 3 miles everyday, 4-5 days/wk

trying to get back in shape.

On Lipitor could not even walk half a block my muscles were so weak

and I felt sick all the time so I stopped.

Diet: Dashing with low glycemic carbs very rarely red meat and

mainly white chicken and fish

Weight: 115 lbs, bmi=20, height: 5.2,

What was you baseline complete lipid profile? and why were statins recommended?

Your BMIl, gender and age would suggest that you are not at high risk and some would not use statins.

Have you and your Dr assessed your Framingham risk score to see if you fit lipid ATP guidelines.

What is your family Hx of early heart disease (men before 55 women before 65).

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 14, 2006

In a message dated 5/13/06 2:43:03 PM, farahbar@... writes:

Trig =150

With spiro I was walking minimum 3 miles everyday, 4-5 days/wk

trying to get back in shape.

On Lipitor could not even walk half a block my muscles were so weak

and I felt sick all the time so I stopped.

Diet: Dashing with low glycemic carbs very rarely red meat and

mainly white chicken and fish

Weight: 115 lbs, bmi=20, height: 5.2,

I definitely put the blame on spiro and Inspra.

PS I assume all . were measured with 12 hr fast

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 14, 2006

In a message dated 5/13/06 2:43:03 PM, farahbar@... writes:

Trig =150

With spiro I was walking minimum 3 miles everyday, 4-5 days/wk

trying to get back in shape.

On Lipitor could not even walk half a block my muscles were so weak

and I felt sick all the time so I stopped.

Diet: Dashing with low glycemic carbs very rarely red meat and

mainly white chicken and fish

Weight: 115 lbs, bmi=20, height: 5.2,

I definitely put the blame on spiro and Inspra.

Tri of 150 on spiro would suggest it is not the culprit.

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 14, 2006

In a message dated 5/14/06 7:07:28 PM, bayabas76@... writes:

He added

allopurinol and crestor(statin)

Have you had gout? (that is what allopurinol is for)

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 15, 2006

In a message dated 5/15/06 2:57:04 AM, bayabas76@... writes:

> Have you had gout? (that is what allopurinol is for)

>

Yes, I am having recurrent gout attacks which is less frequent now

after having been pulled off Furosemides. My BUN and creatinine has

also improved in two weeks. Here are my recent readings: BUN 6.00

mmol/L, CREA 152umol/L, Sodium 138mmol/L, Potassium 4.00 mmol/L. My

readings two weeks ago for comparison: BUN 7.60mmol/L, CREA 169 umol/L,

Na 137 mmol/L, K 3.80mmol/L.

Spiro is now at 100mg bid, Metoprolol is also taken off.My only other

antihypertensive is felodipine 10mg once a day.

Regards.

May 15, 2006

In a message dated 5/15/06 6:02:41 PM, bayabas76@... writes:

Is the Spiro100mg bid safe as a long-term therapeutic regimen if my bp

stays good? Is there a possibility of tapering down the dosage

eventually? My doctor says no to lowering it.

Seems to be, no good trials for years. If BP does well for a year and you are DASHing it would be reasonable to step down slowly with your Drs. following you.

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 17, 2006

In a message dated 5/17/06 3:51:27 PM, frand.2@... writes:

After I found out that I had hyperaldosterone, I

thought it was connected to the triglycerides since they jumped up so

suddenly. I had been walking before my bp jumped up and then quit

but surely that wouldn't have caused my triglyceride level to double.

Tris are most sensitive to diet and with your drug reaction problem Hx I would really work on that first. Your HDL is very low and I would repeat it just to see. Have others in your family been checked for very low HDL.

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure

Clinical Professor of Medicine, Medical College of Wisconsin

May 19, 2006

The oil without the fish has more mixed results. I know a study

proceeding now on 1500 pts. A 10 year trial, following 1500 for ten

years. It looks like people who don't like fish do, however, get used

to the taste and start liking it fast. Like the removal of salt,

tastes seem malleable in a hurry. Several who hated fish now relish

sardines, halibut, salmon and herring. The Omega-rich species that can

readily be gotten in wild versions.

Go figure.

Dave

On May 19, 2006, at 8:46 AM, pagirl1946 wrote:

> One doctor told me to take fish oil instead of Lipitor so I tried it

> for a while. My triglycerides went back up to 500.

>

>>

>> Triglycerides can be lowered by reducing your carbohydrates such as

>> breads and sugary stuff rather than fat & increasing your protein

>> such as fish and chicken. Increasing your omega 3 & 6( fish oil and

>> oils from the nuts) can actually reduce your trig.

>>

May 19, 2006

In a message dated 5/19/06 1:13:56 AM, farahbar@... writes:

I don't do

> the DASH diet, I don't believe in it. Do you have any statistics

on

> how many people in this group have tried it and had lower bp as a

> result?

Get the book and read it and decide for your self.

You can always play the game You bet your life!

May your pressure be low!

CE Grim, BS(Chem/Math), MS(Biochem), MD.

Board Certified in Internal Medicine, Geriatrics and Hypertension

Former Epidemiologic Intelligence Services Officer (Lt. Comdr.), CDC

Specializing in Difficult to Manage High Blood Pressure