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In a message dated 5/24/05 7:41:00 PM, leslie@... writes:

Aldosterone: 61(with an H and NOTE next to it)

Renin: 4.6(with a NOTE) marking next to it

This tells us that the aldo effect is being blocked and renin has risen. This is good.

ACTH 9.6 (with an L and NOTE next to it)

Have no idea why this was measured or how to interpret it.

Sodium 133 (low marked, normal indicated as 135-145)

Again this indicates that the aldo and DASH are working. ONe way to increase it is to lower the sprio come more and drink less.

I would not increase sodium intake as this will tend to increase BP and lower K.

Potassium ser/plas 4.1

Excellent-the sprio is working.

 

My doctor told me to add more salt to my food intake.

I would recommend lowering the spiro.

Question: Why my aldosterone is much higher than it was 3 months ago? Is it because I am taking spironolactone now?

Aldo is driven by renin and as renin (and AII) increases aldo increases. I would decresae the spiro rather than eat more salt.

 

It has been about  40 days since I've been on medication. I started with 100 mg spiro and last two weeks cut to 50 mg/day. I still dash, was under 1200 sodium or under as of yesterday I have increased it. I dont know how much I just added salt to my food. My breathing and gasping for air is much better today.my bp is averaging 120/80.

 

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

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Greetings Dr. Grim and all:

My doctor wanted me to repeat my blood tests following taking spiro a few weeks:

Before spiro my last lab results were as follows(which let to a cat scan and AVS) + spiro + dash:(just to refresh your mind, cat scan showed a 5mm adenoma on left side, AVS appears not to have been done right)

Aldosterone: 43

Renin: < .2

Potassium: 3

my new results are as follows:

Aldosterone: 61(with an H and NOTE next to it)

Renin: 4.6(with a NOTE) marking next to it

ACTH 9.6 (with an L and NOTE next to it)

Sodium 133 (low marked, normal indicated as 135-145)

Potassium ser/plas 4.1

My doctor told me to add more salt to my food intake.

Question: Why my aldosterone is much higher than it was 3 months ago? Is it because I am taking spironolactone now?

It has been about 40 days since I've been on medication. I started with 100 mg spiro and last two weeks cut to 50 mg/day. I still dash, was under 1200 sodium or under as of yesterday I have increased it. I dont know how much I just added salt to my food. My breathing and gasping for air is much better today.my bp is averaging 120/80.

I appreciate your comments Dr. Grim and everyone. Thank you.

Farah

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In a message dated 5/25/05 6:39:21 AM, dave@... writes:

Yes, my primary is an association president, and says most docs believe

that if you add salt you'll reduce the risk of K going too high.  I

tried upping from my DASH of 1500mg / day to 2500, and immediately got

a liquid retention episode.  Back down, OK again.

>>

What Association? How much exp does he have with sprio and HTN and K? Based on your Hx you are not likely to get too high a K.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

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On May 24, 2005, at 6:57 PM, lowerbp2@... wrote:

>

> In a message dated 5/24/05 7:41:00 PM, leslie@... writes:

>

>

>> Aldosterone: 61(with an H and NOTE next to it)

>> Renin: 4.6(with a NOTE) marking next to it

>

> This tells us that the aldo effect is being blocked and renin has

> risen.  This is good.

>

>> Sodium 133 (low marked, normal indicated as 135-145)

>

> Again this indicates that the aldo and DASH are working. ONe way to

> increase it is to lower the sprio come more and drink less.

>

> I would not increase sodium intake as this will tend to increase BP

> and lower K.

>

>> Potassium ser/plas 4.1

>

> Excellent-the sprio is working.

>

>>  

>> My doctor told me to add more salt to my food intake.

>

> I would recommend lowering the spiro.

Yes, my primary is an association president, and says most docs believe

that if you add salt you'll reduce the risk of K going too high. I

tried upping from my DASH of 1500mg / day to 2500, and immediately got

a liquid retention episode. Back down, OK again.

>>

>> Question: Why my aldosterone is much higher than it was 3 months

>> ago? Is it because I am taking spironolactone now?

>

> Aldo is driven by renin and as renin (and AII) increases aldo

> increases.  I      would decresae the spiro rather than eat more salt.

>

>>  

>> It has been about  40 days since I've been on medication. I started

>> with 100 mg spiro and last two weeks cut to 50 mg/day. I still dash,

>> was under 1200 sodium or under as of yesterday I have increased it. I

>> dont know how much I just added salt to my food. My breathing and

>> gasping for air is much better today.my bp is averaging 120/80.

>>  

>>

>

>

> Congratulations! This must find you very happy!

Dave

>

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Spiro to the rescue! I took BP meds for 5 years, and was awarded with

140-150 / 90-95, and LVH as a result. Once I got spiro going, my A/R

became normal and my BP stays at 125/76.

Congrats!

Dave

On May 24, 2005, at 4:03 PM, Farah Rahbar wrote:

> Greetings Dr. Grim and all:

>  My doctor wanted me to repeat my blood tests following taking spiro a

> few weeks:

>  

> Before spiro my last lab results were as follows(which let to a cat

> scan and AVS) + spiro + dash:(just to refresh your mind, cat scan

> showed a 5mm adenoma on left side, AVS appears not to have been done

> right)

>  

> Aldosterone:  43

> Renin:   < .2

> Potassium: 3

>  

> my new results are as follows:

>  

> Aldosterone: 61(with an H and NOTE next to it)

> Renin: 4.6(with a NOTE) marking next to it

> ACTH 9.6 (with an L and NOTE next to it)

> Sodium 133 (low marked, normal indicated as 135-145)

> Potassium ser/plas 4.1

>  

> My doctor told me to add more salt to my food intake.

>

> Question: Why my aldosterone is much higher than it was 3 months ago?

> Is it because I am taking spironolactone now?

>  

> It has been about  40 days since I've been on medication. I started

> with 100 mg spiro and last two weeks cut to 50 mg/day. I still dash,

> was under 1200 sodium or under as of yesterday I have increased it. I

> dont know how much I just added salt to my food. My breathing and

> gasping for air is much better today.my bp is averaging 120/80.

>  

> I appreciate your comments Dr. Grim and everyone. Thank you.

>  

> Farah

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That is becoming clear. He is president of the East Bay Cardiologists.

This, he said, " is common opinon among doctors, and told to hundred of

patients. " He did not insist it was always right, as individual

patients vary. But when I confronted him, he said " that is what we

were taught in the early 60's. " Where? Harvard.

He was just trying to spare me more suffering from taking too extreme

an action. But I told him the 1500mg sodium has been dramatically

better, at least in my liquid retention. But he also is the only guy

in my city who reads up on PA, or tries to. Everyone else seems

afraid. I discovered this via the medical staff, and then execs at

Washington Hospital, where most do some practice or study. They are

ready for a talk at their Monday Rounds weekly lecture series.

Footnotes welcome. That TIME article is in all the offices.

The thing you both have agreed upon is to do one change (med, diet,

exercise) at a time to see what my reaction is without confusion.

And, to gradually add to my pulmonary rehab exercise, tracking with a

step meter. That seems a good generality, as too much too fast can be

damaging to any organism. This is what I think inspired the salt

opinion. And early 60's Harvard med school. Unfortunately it was

incorrect in my case. Now we know.

Dave

On May 25, 2005, at 7:21 AM, lowerbp2@... wrote:

>

> In a message dated 5/25/05 6:39:21 AM, dave@... writes:

>

>

>> Yes, my primary is an association president, and says most docs

>> believe

>> that if you add salt you'll reduce the risk of K going too high.  I

>> tried upping from my DASH of 1500mg / day to 2500, and immediately

>> got

>> a liquid retention episode.  Back down, OK again.

>> >>

>

>

> What Association?  How much exp does he have with sprio and HTN and

> K?  Based on your Hx you are not likely to get too high a K. 

>

>

>

> May your pressure be low!

>

> Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

> Clinical Professor of Medicine and Epidemiology

> Director, Hypertension Diagnosis and Treatment Center

> Board Certified in Internal Medicine, Geriatrics and Hypertension

>

> Published over 220 scientific papers, book chapters and 220 abstracts

> in the area of high blood pressure epidemiology, physiology,

> endocrinology measurement, treatment and how to detect curable causes.

> Listed in Best Doctors in America

> Specializing in Difficult to Control High Blood Pressure and the

> History and Physiology of High Blood pressure in the African Diaspora

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This sounds like a good plan. I also trained in the later 60s at Duke where the rice diet was king. So lets keep working together and do things slowly.

May your pressure be low!CE Grim MDClinical Professor of Internal MedicineProfessor of EpidemiologyBoard Certified in Internal Medicine, Geriatrics and Hypertension

Re: my new test results

That is becoming clear. He is president of the East Bay Cardiologists. This, he said, "is common opinon among doctors, and told to hundred of patients." He did not insist it was always right, as individual patients vary. But when I confronted him, he said "that is what we were taught in the early 60's." Where? Harvard. He was just trying to spare me more suffering from taking too extreme an action. But I told him the 1500mg sodium has been dramatically better, at least in my liquid retention. But he also is the only guy in my city who reads up on PA, or tries to. Everyone else seems afraid. I discovered this via the medical staff, and then execs at Washington Hospital, where most do some practice or study. They are ready for a talk at their Monday Rounds weekly lecture series. Footnotes welcome. That TIME article is in all the offices. The thing you both have agreed upon is to do one change (med, diet, exercise) at a time to see what my reaction is without confusion. And, to gradually add to my pulmonary rehab exercise, tracking with a step meter. That seems a good generality, as too much too fast can be damaging to any organism. This is what I think inspired the salt opinion. And early 60's Harvard med school. Unfortunately it was incorrect in my case. Now we know. Dave On May 25, 2005, at 7:21 AM, lowerbp2@... wrote: > > In a message dated 5/25/05 6:39:21 AM, dave@... writes: > > >> Yes, my primary is an association president, and says most docs >> believe >> that if you add salt you'll reduce the risk of K going too high. I >> tried upping from my DASH of 1500mg / day to 2500, and immediately >> got >> a liquid retention episode. Back down, OK again. >> >> > > > What Association? How much exp does he have with sprio and HTN and > K? Based on your Hx you are not likely to get too high a K. > > > > May your pressure be low! > > Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS > Clinical Professor of Medicine and Epidemiology > Director, Hypertension Diagnosis and Treatment Center > Board Certified in Internal Medicine, Geriatrics and Hypertension > > Published over 220 scientific papers, book chapters and 220 abstracts > in the area of high blood pressure epidemiology, physiology, > endocrinology measurement, treatment and how to detect curable causes. > Listed in Best Doctors in America > Specializing in Difficult to Control High Blood Pressure and the > History and Physiology of High Blood pressure in the African Diaspora

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