Guest guest Posted March 29, 2005 Report Share Posted March 29, 2005 Hi, Dr. Grim and All: I wonder if any theory has been put forward to explain why intolerance of prescription drugs for blood pressure has been so common with PA. I wonder if this effect might be caused by a problem with the kidneys, like PA itself is. For example, is it possible that the medications are being retained by the kidneys, like salt is in PA? Or that medications remain in higer levels in the body because of the ineffectiveness of the kidneys in concentrating urine? Or is it simply that we end up with higher doses of medication because our doctors rapidly titrate us to higher levels of the meds than we can tolerate, because they don't work for us? For PAers with difficulty tolerating prescription medications on the list, is this problem limited to blood pressure meds, or does it apply to other medications, too? Does this intolerance seem to improve on Inspra or Spironolactone? In my experience, I get side effects from virtually any medications I take. I have not added any new medications since going on Spironolactone, so I can't add any information there. It would be useful to know if I were likely to become more tolerant of prescription meds during treatment with Spironolactone. I know my doctors would probably be delighted (although I doubt I would jump up and start demanding prescription medications, knowing me--I've become " drug-resistant " in more ways than one)! Warmly, Pam " I'd rather learn from one bird how to sing, than to teach ten thousand stars how not to dance. " __________________________________________________ Quote Link to comment Share on other sites More sharing options...
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