Re: Conns syndrome post operative

[Guest guest]

In a message dated 12/30/04 15:11:29, hopelesslyob@... writes:

Has anyone out there experience a fast weight gain after having

their adrenal tumor and gland removed

would be unusual. What meds are you on post op? What meds were you on before?

Did you quit smoking?

Are you eating more and exercising less after the surgery-most likely cause.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

In a message dated 1/1/05 8:04:49, bev2454@... writes:

I believe I have lost muscle mass since starting

Spironolactone. 

This has not been reported but many lose some weight due to getting rid of excess body sodium.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

In a message dated 12/31/04 23:15:54, bev2454@... writes:

Hi beth,

I had been on a losing spree(wasn't really trying) for about a year

prior to starting Spiro. I had lost about 20 lbs. Everything that I

had lost is now back, plus a pound or two..... =P This means that my

losing spree has stopped, and now I'm gaining. Something I really did

not need to do.  Shortly after starting the Spiro though, my primary

care dr. put me on Avandia, as well as the metformin I was already

on. Now he has me on a combination of the two, avandamet. Can't say

which medicine it is, but I'm certainly not a happy camper about it.....

This is the most likely to cause weight gain. If spiro is controlling your K you shoulf need less DM meds. What is your HB A1C. This is whast should be used as a guide to how your DM is doing. What goal have they given you?

On the other hand, my New Year's resolution is to attain better

health, meaning better control of my diabetes, more exercise, and a

better mental(and spiritual) attitude about life in general. It's been

a tough year at my house. I lost my mom to cancer in February, and it

was not long after that that I started showing signs of the low K.....

I'm assuming that traumatic events can trigger the onset of such

things. Dr. Grim, any comments on that?

Dont know about data on stress and K but if ACTH goes up and cortisol goes up DM and K can worsen in theory.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

In a message dated 12/31/04 22:21:48, leslie@... writes:

I gained weight after switching from Spiro to Inspra, but I don't attribute it directly to the Inspra.  I have noticed that I have more PMS symptoms and blemishes on Inspra than I did on Spiro, both of which will cause me to eat more because I am a stress eater.  For what it's worth, with some effort, I did lose a significant amount of weight last year while on 50 mg of Spiro (around 60 pounds).

 

Good work the secret is to eat less and exercise more. DASH would be my recommendation if you cook for yourself.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

> > Has anyone out there experience a fast weight gain after having

> > their adrenal tumor and gland removed

I have to admit I saw the same problem. I have always been

thin, and never had problems gaining weight, just the opposite. On

radiation therapy for prostate cancer, had a great deal of tissue

damage and pain. Weight dropped from 168 to 159. To cope with

tissue inflamation, it was decided to try spiro. Went to Inspra when

it became available. Current weight is 180, on a 5' 9 " frame.

Agree that increase muscle mass is important to maintain

weight. I work out in the weight room three times a week. Off for 2

weeks, due to holidays, and up a couple of pounds. Wayne

[Guest guest]

Thanks to all who answered my inquiry. It looks to me that Spiro can cause you to gain weight in the beginning, but that it is possible to lose it. Dr. Grimm, can I get the DASH book on Amazon?

For those that switched from Spiro to Inspra, what caused you to switch. I'm curious, if you'd like to share.

-----Original Message-----From: lowerbp2@... [mailto:lowerbp2@...] Sent: Saturday, January 01, 2005 1:53 PMhyperaldosteronism Subject: Re: Conns syndrome post operativeIn a message dated 12/31/04 22:21:48, leslie@... writes:

I gained weight after switching from Spiro to Inspra, but I don't attribute it directly to the Inspra. I have noticed that I have more PMS symptoms and blemishes on Inspra than I did on Spiro, both of which will cause me to eat more because I am a stress eater. For what it's worth, with some effort, I did lose a significant amount of weight last year while on 50 mg of Spiro (around 60 pounds). Good work the secret is to eat less and exercise more. DASH would be my recommendation if you cook for yourself. May your pressure be low!Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHSClinical Professor of Medicine and EpidemiologyDirector, Hypertension Diagnosis and Treatment CenterBoard Certified in Internal Medicine, Geriatrics and HypertensionPublished over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.Listed in Best Doctors in AmericaSpecializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

I ordered the DASH book from Amazon, here's the link: http://www.amazon.com/exec/obidos/tg/detail/-/0743410076/qid=1104696372/sr=8-2/ref=pd_csp_2/104-7243196-2129534?v=glance & s=books & n=507846

Watching the sodium can help with weight, I have fluctuated by as much as 10 pounds or 1 dress size in a day just in water weight when not eating properly. I started out at a higher dose of Spiro and was able to lower it as my weight dropped (real weight, not just water... I kept a close eye on body fat percentage). I was on a very restrictive diet and consumed very little sodium. I found losing weight to be difficult whether on Spiro or Inspra, I averaged a loss of 2 - 2.5 pounds per week over a 6 month period during which I consumed 500 - 600 calories a day in the form of protein supplements (under very close medical supervision). I've gained 20 pounds back after a month long course of steriods which I've had difficulty losing.

For me exercise is the critical missing component. My muscles fatigue and cramp easily although I used to be very strong. I originally attributed this to low K, but I take supplements to correct this. I worked out moderately last Tuesday and my legs are still sore today and cramp up on stairs, etc. I've got a Dr. appt. tomorrow and will probably ask to have my K checked again. (I also think I did something to my rotator cuff, too. I fell down the stairs about two months ago, grabbed the railing and felt something pop. Its a little better, but still hurts when I reach in certain directions or carry something heavy. I just chalked it up to age, though, not meds. Going to be a ripe old 35 next month!)

As for Spiro vs. Inspra - I changed to see if it would get rid of a small amount of galactorrhea (never completely dried up after nursing my son). It did seem to help, not 100% but things have improved. I wrote a longer summary a few weeks back, but here is the latest and greatest - menses regularity has greatly improved on Inspra, but along with this came PMS and break-outs which I didn't have on Spiro (although on Spiro, periods varied between 2 weeks to 3 months apart). Poor libido - no change (although, it's hard to get in the mood when you're cranky, 20 lbs overweight and look like a pizza-faced teenager!). Actually, I was thinking about sending Dr. Grim a note for his thoughts on switching back to Spiro.

I hope this helps!

RE: Conns syndrome post operative

Thanks to all who answered my inquiry. It looks to me that Spiro can cause you to gain weight in the beginning, but that it is possible to lose it. Dr. Grimm, can I get the DASH book on Amazon?

For those that switched from Spiro to Inspra, what caused you to switch. I'm curious, if you'd like to share.

-----Original Message-----From: lowerbp2@... [mailto:lowerbp2@...] Sent: Saturday, January 01, 2005 1:53 PMhyperaldosteronism Subject: Re: Conns syndrome post operativeIn a message dated 12/31/04 22:21:48, leslie@... writes:

I gained weight after switching from Spiro to Inspra, but I don't attribute it directly to the Inspra. I have noticed that I have more PMS symptoms and blemishes on Inspra than I did on Spiro, both of which will cause me to eat more because I am a stress eater. For what it's worth, with some effort, I did lose a significant amount of weight last year while on 50 mg of Spiro (around 60 pounds). Good work the secret is to eat less and exercise more. DASH would be my recommendation if you cook for yourself. May your pressure be low!Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHSClinical Professor of Medicine and EpidemiologyDirector, Hypertension Diagnosis and Treatment CenterBoard Certified in Internal Medicine, Geriatrics and HypertensionPublished over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.Listed in Best Doctors in AmericaSpecializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

Hi Everyone and Happy New Year!!

I found my copy of the DASH book at Waldenbooks. I think any of the major Book

outlets would have it or can order it. I'd be very surprised if Amazon didn't

have it.

I switched from Spiro to Inspra 10-13-04 after 8 months on Spiro. I was getting

(gynemastis)mispelled, but resulting in sore and enlarging nipples and breasts,

not cool on a male. I gained a little weight on Spiro, but I blame that on

feeling so lousy and not being as active. Spiro was a lot more unsetting to my

stomach than Inspra. I was on 150 mg a day of Spiro and am now on 200mg daily

of Inspra and nothing else. I have tried lot of ways to reduce the dosage but

it seems to be the magic amount for me. Just reducing 25 mg a day returns a

lousy feeling and headaches.

Another big factor for me is the sodium intake, you are on the right track going

for the DASH diet. I maintain a diet of 700 to 900 mg daily of sodium. If I

mess up I have a headache in about 2 hours and it takes about 2 days to return

to normal. I can't fast from sodium for say two meals and then eat a full days

sodium amount in one meal or I get the same result. I can handle 200 to 300 mg

in a meal if I go over, I start with the headache again.

?????On a side note, if I screw up and overdose myself with sodium, for about 2

days my urine has a very distinct and extra horrible odor????????????

Thanx for being in this forum for me, I hope this helps.

Sincerely, Randy

<>< May we all be DASHing! ><>

Thanks to all who answered my inquiry. It looks to me that Spiro can cause you

to gain weight in the beginning, but that it is possible to lose it. Dr. Grimm,

can I get the DASH book on Amazon?

For those that switched from Spiro to Inspra, what caused you to switch. I'm

curious, if you'd like to share.

[Guest guest]

In a message dated 1/2/05 23:30:00, sheltonlayne@... writes:

?????On a side note, if I screw up and overdose myself with sodium, for about 2 days my urine has a very distinct and extra horrible odor???????????? 

Most likely something you ate. Classic would be asparagus.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

In a message dated 1/3/05 1:44:18, lord_mike_the_great@... writes:

You will most definitely lose muscle mass with spiro, since it

blocks testosterone.

Thanks,

Mike

Dont know any hard data on loss of muscle mass with Sprio. I have never had a pt complain of it but I haven't asked either.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

They need to market it for HTN for which it is approved.

May your pressure be low!

Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHS

Clinical Professor of Medicine and Epidemiology

Director, Hypertension Diagnosis and Treatment Center

Board Certified in Internal Medicine, Geriatrics and Hypertension

Published over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.

Listed in Best Doctors in America

Specializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

ok im complaining lost it

Re: Re: Conns syndrome post operative

In a message dated 1/3/05 1:44:18, lord_mike_the_great@... writes:

You will most definitely lose muscle mass with spiro, since itblocks testosterone.Thanks,MikeDont know any hard data on loss of muscle mass with Sprio. I have never had a pt complain of it but I haven't asked either.May your pressure be low!Clarence E. Grim, BS (Chem/Math), MS (Biochem), MD, FACP, FACC, FAHSClinical Professor of Medicine and EpidemiologyDirector, Hypertension Diagnosis and Treatment CenterBoard Certified in Internal Medicine, Geriatrics and HypertensionPublished over 220 scientific papers, book chapters and 220 abstracts in the area of high blood pressure epidemiology, physiology, endocrinology measurement, treatment and how to detect curable causes.Listed in Best Doctors in AmericaSpecializing in Difficult to Control High Blood Pressure and the History and Physiology of High Blood pressure in the African Diaspora

[Guest guest]

Hi

I'm not complaining, but I lost it.

It looked kinda odd on me. I look more feminine now,

although no one would ever have taken me for a man.

Warmly,

Pam

--- THE HOUSE <thewhiningpplz@...> wrote:

> ok im complaining lost it

> Re: Re: Conns

> syndrome post operative

>

>

>

> In a message dated 1/3/05 1:44:18,

> lord_mike_the_great@... writes:

>

>

>

>

> You will most definitely lose muscle mass with

> spiro, since it

> blocks testosterone.

>

> Thanks,

>

> Mike

>

>

>

> Dont know any hard data on loss of muscle mass

> with Sprio. I have never had a pt complain of it

> but I haven't asked either.

>

>

>

> May your pressure be low!

>

> Clarence E. Grim, BS (Chem/Math), MS (Biochem),

> MD, FACP, FACC, FAHS

> Clinical Professor of Medicine and Epidemiology

> Director, Hypertension Diagnosis and Treatment

> Center

> Board Certified in Internal Medicine, Geriatrics

> and Hypertension

>

> Published over 220 scientific papers, book

> chapters and 220 abstracts in the area of high blood

> pressure epidemiology, physiology, endocrinology

> measurement, treatment and how to detect curable

> causes.

> Listed in Best Doctors in America

> Specializing in Difficult to Control High Blood

> Pressure and the History and Physiology of High

> Blood pressure in the African Diaspora

>

>

>

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