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Re: Inspra Side Effects (spliting tablets 1/2 AM and 1/2 PM)

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Regarding my blood pressure, it seems to be 130/83 in the morning at

9:30 AM and then 137/92 in the evening at 9:30 PM.

Is that common?

I have been taking 12.5 mg (1/2 tablet of Inspra in the morning with

5 mg. of Norvasc.

I will try taking 12.5 mg of Inspra in the morning and 12.5 mg at

night to see if I can tolerate it and hopefully get a better blood

pressure reading at night.

Is it advisable to split the Norvasc 5 mg. into 2.5 mg in the

morning and 2.5 mg at night or does it not really matter?

Any suggestions would be appreciated.

> > > I would be surprised if these were due to Inspra this fast, but

> > then as this

> > > is a drug few of us have used yet will need to keep tabs on

this

> > site I think.

> > >

> > >

> > > Has your weight gone up or down?

> > >

> > > Are you getting up at night

> >

> >

> >

> > > In a message dated 1/6/04 14:32:58, airlinerg@r... writes:

> > >

> > >

> > > > I have taken Inspra (eplerenone) 25 mg instead of Midamor

> > (amiloride

> > > > HBr) 5 mg for 3 days now.

> > > >

> > > > My side effects from Inspra (eplerenone) at 25 mg:

> > > >

> > > > 1. strong metallic taste

> > > > 2. very thirsty

> > > > 3. bad headache

> > > > 4. feeling very dried out

> > > > 5. increased urination

> > > > 6. feeling fatigued

> > > > 7. feeling nervous

> > > >

> > > > The worst side effect for me is this bad headache because I

> > already

> > > > have fibromyalgia as well.

> > > >

> > > > My blood pressure is 130/85 to 135/90.

> > > >

> > > >

> > > >

> > > > Here is the medication I am currently taking:

> > > >

> > > > ________

> > > >

> > > > Morning:

> > > > ________

> > > >

> > > > Inspra (eplernone) 25 mg   [replaced Midamor (amiloride

> > > > hydrochloride) 5 mg with Inspra 25 mg on January 3, 2004]

> > > > Norvasc (amlodipine besylate) 5 mg

> > > > Vitamin C 500 mg

> > > > Vitamin E 400 iu

> > > > Multivitamin

> > > >

> > > >

> > > > ________

> > > >

> > > > Evening:

> > > > ________

> > > >

> > > > Cardura (doxazosin mesylate) 1 mg

> > > > Celexa (citalopram HBr) 10 mg [increased from 5 mg to 10 mg

on

> > > > January 2, 2004]

> > > > Lipitor (atorvastatin calcium) 10 mg

> > > > Vitamin C 500 mg

> > > >

> > > >

> > > >

> > > > My test results as of November 4, 2003 when I was on the

Midimor

> > > > were:

> > > >

> > > > Potassium             3.9 mmol/l

> > > > Renin                 0.25 ng/ml/hr

> > > > Aldosterone          18  ng/dl

> > > > Triglycerides       167

> > > > Cholesterol         149

> > > > HDL Cholesterol      31

> > > > LDL Cholesterol      85

> > >

> > > > CHOL/HDL Ratio        4.8

> > > >

> > > > As you can see I doubled my Celexa (still a small dose 5 mg

to 10

> > > > mg) a day before starting the Inspra.

> > > >

> > > > I do not know if I should continue the Inspra or if I should

go

> > back

> > > > to the Midamor.  It is difficult to ascertain when you

change 2

> > > > medications at the same time.

> > > >

> > > > I am pretty sure the side effects are from the Inspra though.

> > > >

> > > > Any feedback would be appreciated.

> > > >

> > > >

> > > >

> > > >

> > > >

> > > >

> > > >

> > > >

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I got ANOTHER bad headache and terrible thirstiness from just 12.5

mg Inspra. I am giving up 12.5 mg Inspra and going back to 5 mg

Midamor (amiloride) instead of Inspra 12.5 mg for the time being.

I will be taking again:

Morning:

--------

5 mg Midamor (amiloride)

5 mg Norvasc (amlodipine)

multi-vitamin

500 mg vitamin C

400 IU vitamin E

Evening:

--------

500 mg vitamin C

10 mg Lipitor (atorvastatin)

1 mg Cardura (doxazosin)

Also as low salt diet as possible, and as much exercise as possible.

If anyone has any suggestions, please let me know.

Thanks.

> > > > I would be surprised if these were due to Inspra this fast,

but

> > > then as this

> > > > is a drug few of us have used yet will need to keep tabs on

> this

> > > site I think.

> > > >

> > > >

> > > > Has your weight gone up or down?

> > > >

> > > > Are you getting up at night

> > >

> > >

> > >

> > > > In a message dated 1/6/04 14:32:58, airlinerg@r... writes:

> > > >

> > > >

> > > > > I have taken Inspra (eplerenone) 25 mg instead of Midamor

> > > (amiloride

> > > > > HBr) 5 mg for 3 days now.

> > > > >

> > > > > My side effects from Inspra (eplerenone) at 25 mg:

> > > > >

> > > > > 1. strong metallic taste

> > > > > 2. very thirsty

> > > > > 3. bad headache

> > > > > 4. feeling very dried out

> > > > > 5. increased urination

> > > > > 6. feeling fatigued

> > > > > 7. feeling nervous

> > > > >

> > > > > The worst side effect for me is this bad headache because I

> > > already

> > > > > have fibromyalgia as well.

> > > > >

> > > > > My blood pressure is 130/85 to 135/90.

> > > > >

> > > > >

> > > > >

> > > > > Here is the medication I am currently taking:

> > > > >

> > > > > ________

> > > > >

> > > > > Morning:

> > > > > ________

> > > > >

> > > > > Inspra (eplernone) 25 mg   [replaced Midamor (amiloride

> > > > > hydrochloride) 5 mg with Inspra 25 mg on January 3, 2004]

> > > > > Norvasc (amlodipine besylate) 5 mg

> > > > > Vitamin C 500 mg

> > > > > Vitamin E 400 iu

> > > > > Multivitamin

> > > > >

> > > > >

> > > > > ________

> > > > >

> > > > > Evening:

> > > > > ________

> > > > >

> > > > > Cardura (doxazosin mesylate) 1 mg

> > > > > Celexa (citalopram HBr) 10 mg [increased from 5 mg to 10

mg

> on

> > > > > January 2, 2004]

> > > > > Lipitor (atorvastatin calcium) 10 mg

> > > > > Vitamin C 500 mg

> > > > >

> > > > >

> > > > >

> > > > > My test results as of November 4, 2003 when I was on the

> Midimor

> > > > > were:

> > > > >

> > > > > Potassium             3.9 mmol/l

> > > > > Renin                 0.25 ng/ml/hr

> > > > > Aldosterone          18  ng/dl

> > > > > Triglycerides       167

> > > > > Cholesterol         149

> > > > > HDL Cholesterol      31

> > > > > LDL Cholesterol      85

> > > >

> > > > > CHOL/HDL Ratio        4.8

> > > > >

> > > > > As you can see I doubled my Celexa (still a small dose 5

mg

> to 10

> > > > > mg) a day before starting the Inspra.

> > > > >

> > > > > I do not know if I should continue the Inspra or if I

should

> go

> > > back

> > > > > to the Midamor.  It is difficult to ascertain when you

> change 2

> > > > > medications at the same time.

> > > > >

> > > > > I am pretty sure the side effects are from the Inspra

though.

> > > > >

> > > > > Any feedback would be appreciated.

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

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