Re: onion cures osteoporosis?

[Guest guest]

Thanks, Rodney! This is exactly what I was looking for. Any ideas on how to find people who have increased their onion intake in an effort to improve bone density? Anecdotal evidence would be great. I can't believe no one has followed up on this in 7 years! It sounds so promising and so simple... Thanks again for your help. Rodney <perspect1111@...> wrote: Hi Ad:Try

this:"Some vegetables (commonly consumed by humans) efficiently modulate bone metabolism.Muhlbauer RC, Li F, Lozano A, Reinli A, Tschudi I.Bone Biology Group, Department Clinical Research, University of Bern, Switzerland. roman.muhlbauerdkf5 (DOT) unibe.chWe have hypothesized that some vegetables which are part of the regular human diet may contain modulators of bone metabolism. To mimic a typical Western diet with large proportions of refined components, rats were pair-fed a semi-purified diet to which, in the treated animals, the dried material under investigation was added. Effects are expressed as % of untreated control. Bone parameters in rats were assessed in the proximal tibia by pQCT. Bone resorption (BR) was assessed by the urinary excretion of [3H]-tetracycline from prelabeled rats. Daily administration of 1 g of onion during 4 weeks

increased total bone mineral content by 17.4% (p<0.05), trabecular bone mineral density by 13.6% (p<0.05). One g of onion/day administered to male rats blunted BR by 23-/+5% (p<0.05). Daily administration of onion to ovariectomized rats inhibited BR in a dose-dependent manner. At the highest dose (1.5 g of onion) BR was inhibited by 26-/+4% (p<0.01) as compared to 24-/+3% (p<0.001) for estradiol (27microg/kg/day). An additional 13 vegetables displayed significant effects on BR at the dose of 1g/day. Interestingly, 1g/day of soy did not inhibit BR in this model. Also, skimmed milk, meat and egg (all 1 g/day) were ineffective. Thus, common vegetables consumed by humans potently modulate bone metabolism in the rat. This opens the possibility to develop the basis for a low-cost, safe and effective nutritional approach to osteoporosis."PMID: 15758507Rodney.>> Can anyone point me to the research that this web site references?> > All comments and/or experiences welcome.> > Thanks.> > http://biomedx.com/bones/page6.html> > Late in 1999, researchers reported that, when dried onion was fed to animals, it could reverse the same type of bone loss seen in individuals suffering from osteoporosis.> > When male rats were fed 1 gram of onion powder per day for a period of only four weeks, the mineral content of their bones increased by over 17 percent, thickness increased by almost 15 percent and the mineral density increased by over 13 percent, which is higher than any pharmaceutical treatment. (This effect was greater than that

available using the osteoporosis prescription drug Calcitonin.)> > Even when the ovaries were removed from female rats, the addition of 30 to 1500 mg of dried onion daily prevented the bone loss that would normally have occurred due to the decrease in estrogen levels.> > While similar results to those above have yet to be verified in human tests, it is obvious that the simple onion is very beneficial to health. And its effect on bone health are only the tip of the iceberg. > > > > ---------------------------------> Ring'em or ping'em. Make PC-to-phone calls as low as 1¢/min with Messenger with Voice.>

How low will we go? Check out Messenger’s low PC-to-Phone call rates.

[Guest guest]

Hi Ad:

The following is worth noting. It appears they were using one gram

of onion POWDER daily for the rats.

If I have my arithmetic approximately right, converted to human terms

that means eating 4.5 kg of onion powder in a month. Quite a lot.

Rodney.

> >

> > Can anyone point me to the research that this web site references?

> >

> > All comments and/or experiences welcome.

> >

> > Thanks.

> >

> > http://biomedx.com/bones/page6.html

> >

> > Late in 1999, researchers reported that, when dried onion was fed

> to animals, it could reverse the same type of bone loss seen in

> individuals suffering from osteoporosis.

> >

> > When male rats were fed 1 gram of onion powder per day for a

period

> of only four weeks, the mineral content of their bones increased by

> over 17 percent, thickness increased by almost 15 percent and the

> mineral density increased by over 13 percent, which is higher than

> any pharmaceutical treatment. (This effect was greater than that

> available using the osteoporosis prescription drug Calcitonin.)

> >

> > Even when the ovaries were removed from female rats, the addition

> of 30 to 1500 mg of dried onion daily prevented the bone loss that

> would normally have occurred due to the decrease in estrogen levels.

> >

> > While similar results to those above have yet to be verified in

> human tests, it is obvious that the simple onion is very beneficial

> to health. And its effect on bone health are only the tip of the

> iceberg.

> >

> >

> >

> > ---------------------------------

> > Ring'em or ping'em. Make PC-to-phone calls as low as 1¢/min with

> Messenger with Voice.

> >

>

>

>

>

>

>

> ---------------------------------

> How low will we go? Check out Messenger's low PC-to-Phone

call rates.

>

[Guest guest]

Hi Ad:

Here is another later study by some of the same authors:

PMID: 14608079

It found that other foods had even better bone-building

characteristics than onion powder:

Here the foods are ranked, based on the bone resorption inhibition

effect of an equivalent weight of each in rats, highest (best) listed

at the top:

Garlic

Rosemary

Italian parsley

Sage

Thyme

Regular parsley

Dill

Onion powder

Arugula

Prune

Fennel

Orange

Leek

..................

Perhaps one could make up a mixture containing many of these. Then

it wouldn't all have to be onion powder!

And worth repeating .......... skim milk and soy products showed no

apparent benefit in this study. (LOL. Nothing like doing a few

empirical experiments to, apparently, expose the problem of trying to

draw rational conclusions without taking the trouble to see whether

it actually happens in the real world! Of course it may turn out,

though, that there are problems of some kind with this study also.)

Rodney.

> > Hi Ad:

> >

> > Try this:

> >

> > " Some vegetables (commonly consumed by humans) efficiently

modulate

> > bone metabolism.

> >

> > Muhlbauer RC, Li F, Lozano A, Reinli A, Tschudi I.

> >

> > Bone Biology Group, Department Clinical Research, University of

> Bern,

> > Switzerland. roman.muhlbauer@

> >

> > We have hypothesized that some vegetables which are part of the

> > regular human diet may contain modulators of bone metabolism. To

> > mimic a typical Western diet with large proportions of refined

> > components, rats were pair-fed a semi-purified diet to which, in

> the

> > treated animals, the dried material under investigation was

added.

> > Effects are expressed as % of untreated control. Bone parameters

in

> > rats were assessed in the proximal tibia by pQCT. Bone resorption

> > (BR) was assessed by the urinary excretion of [3H]-tetracycline

> from

> > prelabeled rats. Daily administration of 1 g of onion during 4

> weeks

> > increased total bone mineral content by 17.4% (p<0.05),

trabecular

> > bone mineral density by 13.6% (p<0.05). One g of onion/day

> > administered to male rats blunted BR by 23-/+5% (p<0.05). Daily

> > administration of onion to ovariectomized rats inhibited BR in a

> dose-

> > dependent manner. At the highest dose (1.5 g of onion) BR was

> > inhibited by 26-/+4% (p<0.01) as compared to 24-/+3% (p<0.001)

for

> > estradiol (27microg/kg/day). An additional 13 vegetables

displayed

> > significant effects on BR at the dose of 1g/day. Interestingly,

> > 1g/day of soy did not inhibit BR in this model. Also, skimmed

milk,

> > meat and egg (all 1 g/day) were ineffective. Thus, common

> vegetables

> > consumed by humans potently modulate bone metabolism in the rat.

> This

> > opens the possibility to develop the basis for a low-cost, safe

and

> > effective nutritional approach to osteoporosis. "

> >

> > PMID: 15758507

> >

> > Rodney.

> >

> > --- In , ad min <academy_one@>

wrote:

> > >

> > > Can anyone point me to the research that this web site

references?

> > >

> > > All comments and/or experiences welcome.

> > >

> > > Thanks.

> > >

> > > http://biomedx.com/bones/page6.html

> > >

> > > Late in 1999, researchers reported that, when dried onion was

fed

> > to animals, it could reverse the same type of bone loss seen in

> > individuals suffering from osteoporosis.

> > >

> > > When male rats were fed 1 gram of onion powder per day for a

> period

> > of only four weeks, the mineral content of their bones increased

by

> > over 17 percent, thickness increased by almost 15 percent and the

> > mineral density increased by over 13 percent, which is higher

than

> > any pharmaceutical treatment. (This effect was greater than that

> > available using the osteoporosis prescription drug Calcitonin.)

> > >

> > > Even when the ovaries were removed from female rats, the

addition

> > of 30 to 1500 mg of dried onion daily prevented the bone loss

that

> > would normally have occurred due to the decrease in estrogen

levels.

> > >

> > > While similar results to those above have yet to be verified in

> > human tests, it is obvious that the simple onion is very

beneficial

> > to health. And its effect on bone health are only the tip of the

> > iceberg.

> > >

> > >

> > >

> > > ---------------------------------

> > > Ring'em or ping'em. Make PC-to-phone calls as low as 1¢/min

with

> > Messenger with Voice.

> > >

> >

> >

> >

> >

> >

> >

> > ---------------------------------

> > How low will we go? Check out Messenger's low PC-to-Phone

> call rates.

> >

>